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List of works by Rakez Kayed

A native interactor scaffolds and stabilizes toxic ATAXIN-1 oligomers in SCA1.

scientific article published on 19 May 2015

A specific amyloid-beta protein assembly in the brain impairs memory

scientific journal article published in 2006. 14 July 2022 Editor’s Note: readers are advised to use caution when using results reported therein.

Amyloid Beta Annular Protofibrils in Cell Processes and Synapses Accumulate with Aging and Alzheimer-Associated Genetic Modification ⬇️

scientific article published on July 14, 2009

Amyloid-beta peptide and oligomers in the brain and cerebrospinal fluid of aged canines

scientific article

Amyloid-β Annular Protofibrils Evade Fibrillar Fate in Alzheimer Disease Brain ⬇️

scientific article published on April 20, 2011

Amyloid-β oligomers as a template for secondary amyloidosis in Alzheimer's disease

scientific article published on 15 August 2014

Annular protofibrils are a structurally and functionally distinct type of amyloid oligomer

scientific article

Ataxin-1 oligomers induce local spread of pathology and decreasing them by passive immunization slows Spinocerebellar ataxia type 1 phenotypes.

scientific article published on 17 December 2015

Azure C Targets and Modulates Toxic Tau Oligomers.

scientific article published on 29 January 2018

Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers

scientific article

Characterization of tau oligomeric seeds in progressive supranuclear palsy

scientific article

Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo

scientific article (publication date: 18 February 2005)

Differential Activation of the ER Stress Factor XBP1 by Oligomeric Assemblies ⬇️

scientific article published on April 21, 2012

Drusen deposits associated with aging and age-related macular degeneration contain nonfibrillar amyloid oligomers

scientific article

Dual role of p53 amyloid formation in cancer; loss of function and gain of toxicity.

scientific article

Exercise reverses preamyloid oligomer and prolongs survival in alphaB-crystallin-based desmin-related cardiomyopathy

scholarly article

Formation of soluble amyloid oligomers and amyloid fibrils by the multifunctional protein vitronectin

scientific article published in 2008

Immunotherapy for the treatment of Alzheimer's disease: amyloid-β or tau, which is the right target?

scientific article

Modulating Disease-Relevant Tau Oligomeric Strains by Small Molecules

scientific article published on 31 July 2020

Novel Abeta peptide immunogens modulate plaque pathology and inflammation in a murine model of Alzheimer's disease

scientific article

Preparation and Characterization of Neurotoxic Tau Oligomers ⬇️

scientific article published on November 8, 2010

RNA-binding proteins Musashi and tau soluble aggregates initiate nuclear dysfunction

scientific article published on 27 August 2020

Reversal of amyloid-induced heart disease in desmin-related cardiomyopathy

scientific article

Soluble Abeta oligomers ultrastructurally localize to cell processes and might be related to synaptic dysfunction in Alzheimer's disease brain

scientific article

Soluble and mature amyloid fibrils in drusen deposits

scientific article

Tau Interacts with the C-Terminal Region of α-Synuclein, Promoting Formation of Toxic Aggregates with Distinct Molecular Conformations

scientific article published on 07 June 2019

The formation of tau pore-like structures is prevalent and cell specific: possible implications for the disease phenotypes

scientific article

Therapeutic approaches against common structural features of toxic oligomers shared by multiple amyloidogenic proteins.

scientific article published on 07 January 2014

Toxic human islet amyloid polypeptide (h-IAPP) oligomers are intracellular, and vaccination to induce anti-toxic oligomer antibodies does not prevent h-IAPP-induced beta-cell apoptosis in h-IAPP transgenic mice

scientific article

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