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List of works by Ahcène Boumendjel

1-Azaaurones derived from the naturally occurring aurones as potential antimalarial drugs

scientific article published on 9 June 2010

2-Arylidenedihydroindole-3-ones: design, synthesis, and biological activity on bladder carcinoma cell lines.

scientific article published on 16 October 2006

2-Indolylmethylenebenzofuranones as first effective inhibitors of ABCC2.

scientific article

3-Aryl-4-methyl-2-quinolones targeting multiresistant Staphylococcus aureus bacteria.

scientific article published on 21 February 2013

6-halogenochromones bearing tryptamine: one-step access to potent and highly selective inhibitors of breast cancer resistance protein

scientific article published on 21 May 2012

A Novel Platinum-Maurocalcine Conjugate Induces Apoptosis of Human Glioblastoma Cells by Acting through the ROS-ERK/AKT-p53 Pathway.

scientific article published on 14 October 2015

A novel chalcone derivative which acts as a microtubule depolymerising agent and an inhibitor of P-gp and BCRP in in-vitro and in-vivo glioblastoma models

scientific article

A retro-biosynthetic approach to the prediction of biosynthetic pathways from position-specific isotope analysis as shown for tramadol

scientific article published on 23 June 2015

A synthetic chalcone as a potent inducer of glutathione biosynthesis

scientific article

A template model for studying anticancer drug efflux transporter inhibitors in vitro

scientific article published on 08 August 2012

ABCG2: recent discovery of potent and highly selective inhibitors

scientific article published on June 2013

AG11, a novel dichloroflavanone derivative with anti-mitotic activity towards human bladder cancer cells

scientific article published on October 2013

Acridone derivatives: design, synthesis, and inhibition of breast cancer resistance protein ABCG2.

scientific article published on 13 February 2007

Anticancer multidrug resistance mediated by MRP1: recent advances in the discovery of reversal agents

scientific article

Antimitotic activity of 5-hydroxy-7-methoxy-2-phenyl-4-quinolones.

scientific article published on September 2004

Antimitotic and antiproliferative activities of chalcones: forward structure-activity relationship.

scientific article

Are Human Tyrosinase and Related Proteins Suitable Targets for Melanoma Therapy?

scientific article published on 16 February 2016

Arylthiosemicarbazones as antileishmanial agents

scientific article published on 14 July 2016

Aurone derivatives as promising antibacterial agents against resistant Gram-positive pathogens

scientific article published on 11 January 2019

B-ring modified aurones as promising allosteric inhibitors of hepatitis C virus RNA-dependent RNA polymerase

scientific article published on 4 April 2014

Biomimetic synthesis of Tramadol

scientific article published in 2015

Breast cancer resistance protein (BCRP/ABCG2): new inhibitors and QSAR studies by a 3D linear solvation energy approach.

scientific article

Cellular and molecular mechanisms activating the cell death processes by chalcones: Critical structural effects

scientific article published on 14 October 2013

Chalcone JAI-51 improves efficacy of synchrotron microbeam radiation therapy of brain tumors.

scientific article published on 4 May 2012

Chalcones derivatives acting as cell cycle blockers: potential anti cancer drugs?

scientific article published on April 2009

Chemical composition of the pods of Albizia polyphylla

scientific article published on 16 November 2015

Chromones bearing amino acid residues: Easily accessible and potent inhibitors of the breast cancer resistance protein ABCG2

scientific article published on 05 July 2020

Collateral sensitivity of resistant MRP1-overexpressing cells to flavonoids and derivatives through GSH efflux

scientific article

Design, synthesis and biological evaluation of novel ring-opened cromakalim analogues with relaxant effects on vascular and respiratory smooth muscles and as stimulators of elastin synthesis

scientific article

Dicarboxylate-Oside Detergents for Extraction, Overstabilization and Crystallization of Membrane Proteins.

scientific article published on 29 January 2018

Dicer-mediated upregulation of BCRP confers tamoxifen resistance in human breast cancer cells

scientific article published on 30 August 2011

Discovery of naturally occurring aurones that are potent allosteric inhibitors of hepatitis C virus RNA-dependent RNA polymerase

scientific article published on 6 July 2011

Disruption of Fibers from the Tau Model AcPHF6 by Naturally Occurring Aurones and Synthetic Analogues.

scientific article published on 25 May 2016

Ferrocene-embedded flavonoids targeting the Achilles heel of multidrug-resistant cancer cells through collateral sensitivity

scientific article published on March 2017

Flavonoids as RTK inhibitors and potential anticancer agents

scientific article published on September 2008

General Articles Aurones: A Subclass of Flavones with Promising Biological Potential ⬇️

scientific article published on December 1, 2003

IPP51, a chalcone acting as a microtubule inhibitor with in vivo antitumor activity against bladder carcinoma

scientific article

Identification of specific reversal agents for Leishmania ABCI4-mediated antimony resistance by flavonoid and trolox derivative screening

scientific article published on 14 October 2013

Identification of xanthones as selective killers of cancer cells overexpressing the ABC transporter MRP1.

scientific article published on June 2011

Investigation of a new 1,3-diarylpropenone as a potential antimitotic agent targeting bladder carcinoma.

scientific article

Investigation of chalcones as selective inhibitors of the breast cancer resistance protein: critical role of methoxylation in both inhibition potency and cytotoxicity

scientific article published on 02 April 2012

MBL-II-141, a chromone derivative, enhances irinotecan (CPT-11) anticancer efficiency in ABCG2-positive xenografts

scientific article

MRP1-dependent Collateral Sensitivity of Multidrug-resistant Cancer Cells: Identifying Selective Modulators Inducing Cellular Glutathione Depletion.

scientific article published on 18 November 2016

Make azoles active again: chalcones as potent reversal agents of transporters-mediated resistance in Candida albicans

scientific article published on 25 July 2018

Modulation of P-glycoprotein-mediated multidrug resistance by flavonoid derivatives and analogues

scientific article published in May 2003

Modulation of paclitaxel transport by flavonoid derivatives in human breast cancer cells. Is there a correlation between binding affinity to NBD of P-gp and modulation of transport?

scientific article published on 3 March 2006

Molecular analysis of the massive GSH transport mechanism mediated by the human Multidrug Resistant Protein 1/ABCC1

scientific article published on 06 May 2020

Nauclea latifolia: biological activity and alkaloid phytochemistry of a West African tree

scientific article published on 27 June 2016

New pseudodimeric aurones as palm pocket inhibitors of Hepatitis C virus RNA-dependent RNA polymerase

scientific article

New, highly potent and non-toxic, chromone inhibitors of the human breast cancer resistance protein ABCG2.

scientific article published on 27 June 2016

Occurrence of the synthetic analgesic tramadol in an African medicinal plant

scientific article

Occurrences, biosynthesis and properties of aurones as high-end evolutionary products.

scientific article published on 10 July 2017

Optimization of the chromone scaffold through QSAR and docking studies: Identification of potent inhibitors of ABCG2

scientific article published on 10 October 2019

Ovarian cancer cells cisplatin sensitization agents selected by mass cytometry target ABCC2 inhibition

scientific article published on 31 May 2018

Phytochemical and Biological Investigation of Helianthemum nummularium, a High-Altitude Growing Alpine Plant Overrepresented in Ungulates Diets

scientific article published on 09 July 2020

Piperazinobenzopyranones and phenalkylaminobenzopyranones: potent inhibitors of breast cancer resistance protein (ABCG2).

scientific article published on November 2005

Piperidinyl-embeded chalcones possessing anti PI3Kδ inhibitory properties exhibit anti-atopic properties in preclinical models

scientific article published on 12 September 2018

Quantitative evaluation of the combination between cytotoxic drug and efflux transporter inhibitors based on a tumour growth inhibition model.

scientific article published on 6 February 2013

Recent advances in the discovery of flavonoids and analogs with high-affinity binding to P-glycoprotein responsible for cancer cell multidrug resistance.

scientific article

Structural requirement of arylindolylpropenones as anti-bladder carcinoma cells agents

scientific article published on 16 August 2011

Structure-activity relationships in the development of allosteric hepatitis C virus RNA-dependent RNA polymerase inhibitors: ten years of research

scientific article published on 14 August 2012

Structure-activity relationships of chromone derivatives toward the mechanism of interaction with and inhibition of breast cancer resistance protein ABCG2.

scientific article published on 13 December 2013

Substituted chromones as highly potent nontoxic inhibitors, specific for the breast cancer resistance protein

scientific article published on 06 January 2012

Targeting the Achilles heel of multidrug-resistant cancer by exploiting the fitness cost of resistance

scientific article

The effect of flavonoid derivatives on doxorubicin transport and metabolism.

scientific article published on 4 November 2007

Traditional uses, phytochemistry and pharmacological properties of African Nauclea species: A review ⬇️

scientific article published on 15 October 2017

Two in one: bifonctional derivatives of trolox acting as antimalarial and antioxidant agents

scientific article published on 09 October 2020

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