List of works - Charles S Craik

A Preclinical Assessment of 89Zr-atezolizumab Identifies a Requirement for Carrier Added Formulations Not Observed with 89Zr-C4

scientific article published on 24 September 2018

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

scientific article published on 30 April 2020

A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing ⬇️

journal article from 'bioRxiv' published in 2020

A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells

scientific article published in 2021

Bivalent binding of a fully human IgG to the SARS-CoV-2 spike proteins reveals mechanisms of potent neutralization

scientific article published on 15 July 2020

Discovery and characterization of a thioesterase-specific monoclonal antibody that recognizes the 6-deoxyerythronolide B synthase

scientific article published on 17 October 2018

Discovery of Selective Matriptase and Hepsin Serine Protease Inhibitors: Useful Chemical Tools for Cancer Cell Biology

scientific article published on 04 January 2019

End-Binding E3 Ubiquitin Ligases Enable Protease Signaling

scientific article published on 20 November 2019

Fab-based inhibitors reveal ubiquitin independent functions for HIV Vif neutralization of APOBEC3 restriction factors

scientific article published on 5 January 2018

Identifying a potential biomarker for primary focal segmental glomerulosclerosis and its association with recurrence after transplantation

scientific article published on 21 February 2019

Imaging PD-L1 Expression with ImmunoPET.

scientific article published on 10 November 2017

Immunoproteasome functions explained by divergence in cleavage specificity and regulation.

scientific article published on 28 November 2017

Platform to Discover Protease-Activated Antibiotics and Application to Siderophore-Antibiotic Conjugates

scientific article published on 10 December 2020

Re-emerging Aspartic Protease Targets: Examining <i>Cryptococcus neoformans</i> Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery

scientific article published on 18 May 2021

Specificity for latent C termini links the E3 ubiquitin ligase CHIP to caspases

scientific article published on 18 July 2019

Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients

scientific article published on 25 November 2020

Structure-Function Analysis of the Extended Conformation of a Polyketide Synthase Module

scientific article published on 18 May 2018

Substrate Profiling and High Resolution Co-complex Crystal Structure of a Secreted C11 Protease Conserved across Commensal Bacteria.

scientific article published on 17 April 2017

List of works by Charles S Craik