List of works - Lin Shen

A multicenter, randomized trial comparing efficacy and safety of paclitaxel/capecitabine and cisplatin/capecitabine in advanced gastric cancer.

scientific article published on 27 February 2018

A prospective multicenter phase II study on the efficacy and safety of dasatinib in the treatment of metastatic gastrointestinal stromal tumors failed by imatinib and sunitinib and analysis of NGS in peripheral blood

scientific article published on 17 July 2020

Clinical and Prognostic Value of PET/CT Imaging with Combination of 68Ga-DOTATATE and 18F-FDG in Gastroenteropancreatic Neuroendocrine Neoplasms

scientific article published on 26 February 2018

Clinical implications of plasma ctDNA features and dynamics in gastric cancer treated with HER2-targeted therapies

scientific article published on 01 December 2020

Clinicopathological features and prognostic validity of the European Neuroendocrine Tumor Society (ENETS) and American Joint Committee on Cancer (AJCC) 8th staging systems in colonic neuroendocrine neoplasms

scientific article published on 10 July 2019

EPHA2 blockade reverses acquired resistance to afatinib induced by EPHA2-mediated MAPK pathway activation in gastric cancer cells and avatar mice

scientific article published on 17 April 2019

Establishment and genomic characterizations of patient-derived esophageal squamous cell carcinoma xenograft models using biopsies for treatment optimization.

scientific article

Etoposide and cisplatin versus irinotecan and cisplatin as the first-line therapy for patients with advanced, poorly differentiated gastroenteropancreatic neuroendocrine carcinoma: A randomized phase 2 study

scientific article published on 01 May 2020

Expert consensus on multidisciplinary therapy of colorectal cancer with lung metastases (2019 edition)

scientific article published on 14 February 2019

Genetic variants involved in the cGAS-STING pathway predict outcome in patients with metastatic colorectal cancer: Data from FIRE-3 and TRIBE trials

scientific article published in 2022

Gimatecan exerts potent antitumor activity against gastric cancer in vitro and in vivo via AKT and MAPK signaling pathways.

scientific article published on 13 December 2017

Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells

scientific article published on 16 April 2020

Hepatoid adenocarcinoma of the stomach: a unique subgroup with distinct clinicopathological and molecular features

scientific article published on 15 April 2019

Hyperprogression after immunotherapy in patients with malignant tumors of digestive system

scientific article published on 17 July 2019

Multimodality Treatment Including Triplet Regimen as First-Line Chemotherapy May Improve Prognosis of Serum AFP-Elevated Gastric Cancer with Liver Metastasis.

scientific article published on 24 December 2017

Pharmacokinetics, Safety, and Preliminary Efficacy of Oral Trifluridine/Tipiracil in Chinese Patients with Solid Tumors: A Phase 1b, Open-Label Study

scientific article published on 09 April 2020

Randomized Phase III KEYNOTE-181 Study of Pembrolizumab Versus Chemotherapy in Advanced Esophageal Cancer

scientific article published on 07 October 2020

The current status of and prospects in research regarding gastrointestinal stromal tumors in China