List of works - Kwangsik Nho

18F-florbetapir Positron Emission Tomography-determined Cerebral β-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery

scientific article published in February 2018

A Graph-Based Integration of Multimodal Brain Imaging Data for the Detection of Early Mild Cognitive Impairment (E-MCI)

APOE Promoter Polymorphism-219T/G is an Effect Modifier of the Influence of APOE ε4 on Alzheimer's Disease Risk in a Multiracial Sample

scientific article published on 16 August 2019

APOE effect on Alzheimer's disease biomarkers in older adults with significant memory concern

scientific article

Adult neurogenesis and neurodegenerative diseases: A systems biology perspective

scientific article published on 16 February 2016

Alpha-synuclein (SNCA) polymorphisms exert protective effects on memory after mild traumatic brain injury

scientific article published on 28 July 2016

Altered bile acid profile associates with cognitive impairment in Alzheimer's disease-An emerging role for gut microbiome

Altered bile acid profile associates with cognitive impairment in Alzheimer's disease—An emerging role for gut microbiome

Altered bile acid profile in mild cognitive impairment and Alzheimer's disease: Relationship to neuroimaging and CSF biomarkers

scientific article published on 15 October 2018

Alzheimer's Disease Neuroimaging Initiative biomarkers as quantitative phenotypes: Genetics core aims, progress, and plans

scientific article

Alzheimer's disease genetic risk variants beyond APOE ε4 predict mortality

scientific article published on 14 August 2017

Amyloid pathway-based candidate gene analysis of [(11)C]PiB-PET in the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort

scientific article published on March 2012

Association analysis of rare variants near the APOE region with CSF and neuroimaging biomarkers of Alzheimer's disease

scientific article

Association of Altered Liver Enzymes With Alzheimer Disease Diagnosis, Cognition, Neuroimaging Measures, and Cerebrospinal Fluid Biomarkers

scientific article published on 03 July 2019

Association of blood-based transcriptional risk scores with biomarkers for Alzheimer disease

scientific article published on 30 September 2020

Associations of the Top 20 Alzheimer Disease Risk Variants With Brain Amyloidosis

scientific article published on 16 January 2018

Automatic Prediction of Conversion from Mild Cognitive Impairment to Probable Alzheimer's Disease using Structural Magnetic Resonance Imaging ⬇️

scientific article published on November 13, 2010

Bile acids targeted metabolomics and medication classification data in the ADNI1 and ADNIGO/2 cohorts

scientific article published on 17 October 2019

Brain and blood metabolite signatures of pathology and progression in Alzheimer disease: A targeted metabolomics study.

scientific article published on 25 January 2018

Brain-wide structural connectivity alterations under the control of Alzheimer risk genes

scientific article published on 07 February 2020

Broad phenotype of cysteine altering NOTCH3 variants in UK Biobank: CADASIL to non-penetrance

scientific article published on 30 July 2020

Circulating ethanolamine plasmalogen indices in Alzheimer's disease: Relation to diagnosis, cognition, and CSF tau

scientific article published on 27 July 2020

Codon bias among synonymous rare variants is associated with Alzheimer's disease imaging biomarker

scientific article published in January 2018

Common genetic variants influence human subcortical brain structures

scientific article

Comparing Variability, Severity, and Persistence of Depressive Symptoms as Predictors of Future Stroke Risk

scientific article published on 24 October 2016

Comparison of Multi-Sample Variant Calling Methods for Whole Genome Sequencing

scientific article published in October 2014

Comprehensive gene- and pathway-based analysis of depressive symptoms in older adults

scientific article

Concordant peripheral lipidome signatures in two large clinical studies of Alzheimer's disease

scientific article published on 10 November 2020

Correction: Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation

scientific article published on 21 October 2019

Cortical surface biomarkers for predicting cognitive outcomes using group l2,1 norm

scientific article

Deep Learning in Alzheimer's Disease: Diagnostic Classification and Prognostic Prediction Using Neuroimaging Data

scientific article published on 20 August 2019

Differential co-expression analysis reveals early stage transcriptomic decoupling in alzheimer's disease

scientific article published on 03 April 2020

Dysregulated Fc gamma receptor-mediated phagocytosis pathway in Alzheimer's disease: network-based gene expression analysis

scientific article published on 10 December 2019

Exome Chip Analysis Identifies Low-Frequency a on Brain Magnetic Imaging

From phenotype to genotype: an association study of longitudinal phenotypic markers to Alzheimer's disease relevant SNPs

scientific article

GWAS of longitudinal amyloid accumulation on 18F-florbetapir PET in Alzheimer's disease implicates microglial activation gene IL1RAP.

scientific article

Gene-based GWAS and biological pathway analysis of the resilience of executive functioning

scientific article published on March 2014

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

scholarly article published 28 August 2017

Genetic Influences on Plasma Homocysteine Levels in African Americans and Yoruba Nigerians

scientific article published on 30 October 2015

Genetic analysis of quantitative phenotypes in AD and MCI: imaging, cognition and biomarkers

scientific article (publication date: June 2014)

Genetic architecture of resilience of executive functioning

scientific article published on December 2012

Genetic architecture of subcortical brain structures in 38,851 individuals

scientific article published on 21 October 2019

Genetic studies of quantitative MCI and AD phenotypes in ADNI: Progress, opportunities, and plans

scientific article (publication date: July 2015)

Genetic variants and functional pathways associated with resilience to Alzheimer's disease

scientific article published on 01 August 2020

Genetic variation affecting exon skipping contributes to brain structural atrophy in Alzheimer's disease.

scientific article published on 18 May 2018

Genome-wide association analysis of hippocampal volume identifies enrichment of neurogenesis-related pathways

scientific article published on 10 October 2019

Genome-wide association study of brain amyloid deposition as measured by Pittsburgh Compound-B (PiB)-PET imaging

scientific article published on 25 October 2018

Genome-wide association study of language performance in Alzheimer's disease

scientific article published on 31 May 2017

Genome-wide pathway analysis of memory impairment in the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort implicates gene candidates, canonical pathways, and networks

scientific article published on December 2012

Genome-wide transcriptome analysis identifies novel dysregulated genes implicated in Alzheimer's pathology

scientific article published on 05 August 2020

Genomics and CSF analyses implicate thyroid hormone in hippocampal sclerosis of aging

scientific article published on 4 November 2016

Harnessing peripheral DNA methylation differences in the Alzheimer's Disease Neuroimaging Initiative (ADNI) to reveal novel biomarkers of disease

scientific article published on 15 June 2020

Hippocampal Sclerosis of Aging, a Common Alzheimer's Disease 'Mimic': Risk Genotypes are Associated with Brain Atrophy Outside the Temporal Lobe

scientific article published on 15 March 2016

Hippocampal Surface Mapping of Genetic Risk Factors in AD via Sparse Learning Models

scientific article published on 01 January 2011

Hippocampal transcriptome-guided genetic analysis of correlated episodic memory phenotypes in Alzheimer's disease

scientific article

IDENTIFICATION OF DISCRIMINATIVE IMAGING PROTEOMICS ASSOCIATIONS IN ALZHEIMER'S DISEASE VIA A NOVEL SPARSE CORRELATION MODEL.

scientific article published on January 2016

Identification of Novel Genes Associated with Cortical Thickness in Alzheimer's Disease: Systems Biology Approach to Neuroimaging Endophenotype

scientific article published on 09 April 2020

Identification of common variants associated with human hippocampal and intracranial volumes

scientific article published on 15 April 2012

Identification of exon skipping events associated with Alzheimer's disease in the human hippocampus

scholarly article by Seonggyun Han et al published 31 January 2019 in BMC Medical Genomics

Identification of functionally connected multi-omic biomarkers for Alzheimer's disease using modularity-constrained Lasso

scientific article published on 17 June 2020

Identifying Neuroimaging and Proteomic Biomarkers for MCI and AD via the Elastic Net

article

Identifying quantitative trait loci via group-sparse multitask regression and feature selection: an imaging genetics study of the ADNI cohort

scientific article published on 6 December 2011

Influence of TSPO genotype on 11C-PBR28 standardized uptake values

scientific article published on 19 June 2013

Influence of genetic variation on plasma protein levels in older adults using a multi-analyte panel

scientific article

Initiation of antidepressant medication and risk of incident stroke: using the Adult Changes in Thought cohort to address time-varying confounding

scientific article published on 11 May 2019

Integration of bioinformatics and imaging informatics for identifying rare PSEN1 variants in Alzheimer's disease

scientific article

Knowledge-driven binning approach for rare variant association analysis: application to neuroimaging biomarkers in Alzheimer's disease

scientific article

Late-onset Alzheimer's disease, heating up and foxed by several proteins: pathomolecular effects of the aging process.

scientific article

Longitudinal Genotype-Phenotype Association Study through Temporal Structure Auto-Learning Predictive Model

scientific article published on 01 July 2018

Longitudinal Genotype-Phenotype Association Study via Temporal Structure Auto-Learning Predictive Model

Metabolic network failures in Alzheimer's disease: A biochemical road map.

scientific article published on 21 March 2017

MicroRNA-298 reduces levels of human amyloid-β precursor protein (APP), β-site APP-converting enzyme 1 (BACE1) and specific tau protein moieties

scientific article published on 15 January 2020

MildInt: Deep Learning-Based Multimodal Longitudinal Data Integration Framework

scientific article published on 28 June 2019

Neuropathological correlates and genetic architecture of microglial activation in elderly human brain

scientific article published in Nature Communications

Novel genetic loci associated with hippocampal volume

scientific article published on 18 January 2017

Novel genetic loci underlying human intracranial volume identified through genome-wide association

scientific article (publication date: 3 October 2016)

Plasma Tau Association with Brain Atrophy in Mild Cognitive Impairment and Alzheimer's Disease

scientific article published on 25 May 2017

Predicting Alzheimer's disease progression using multi-modal deep learning approach

scientific article published in Scientific Reports

Progress in Polygenic Composite Scores in Alzheimer's and Other Complex Diseases

scientific article published on 25 March 2019

Protective variant for hippocampal atrophy identified by whole exome sequencing

scientific article

Quantitative trait loci identification for brain endophenotypes via new additive model with random networks

scientific article published on 01 September 2018

Rare variants in the splicing regulatory elements of EXOC3L4 are associated with brain glucose metabolism in Alzheimer's disease

scholarly article by Jason E Miller et al published 14 September 2018 in BMC Medical Genomics

Relationship between baseline brain metabolism measured using [¹⁸F]FDG PET and memory and executive function in prodromal and early Alzheimer's disease

scientific article

Reply

Reply: To PMID 25559091.

scientific article published on 15 July 2015

Reply: To PMID 25559091.

scientific article published on 20 April 2015

Reply: To PMID 25559091.

scientific article published on 18 August 2015

Serum triglycerides in Alzheimer disease: Relation to neuroimaging and CSF biomarkers

scientific article published on 01 May 2020

Sets of coregulated serum lipids are associated with Alzheimer's disease pathophysiology

scientific article published on 05 September 2019

Sex and APOE ε4 genotype modify the Alzheimer's disease serum metabolome

scientific article published on 02 March 2020

Sparse Bayesian Learning for Identifying Imaging Biomarkers in AD Prediction

article published in 2010

Systems modeling of white matter microstructural abnormalities in Alzheimer's disease

scientific article published on 04 February 2020

Targeted genetic analysis of cerebral blood flow imaging phenotypes implicates the INPP5D gene

scientific article published on 18 June 2019

Targeted neurogenesis pathway-based gene analysis identifies ADORA2A associated with hippocampal volume in mild cognitive impairment and Alzheimer's disease

scientific article published on 18 August 2017

Telomere Shortening in the Alzheimer's Disease Neuroimaging Initiative Cohort

scientific article published on 01 January 2019

The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data

scientific article

The effect of reference panels and software tools on genotype imputation ⬇️

scientific article published on October 22, 2011

The effect of the top 20 Alzheimer disease risk genes on gray-matter density and FDG PET brain metabolism

scientific article published on 19 December 2016

The genetic architecture of the human cerebral cortex

scientific article

The interleukin 3 gene (IL3) contributes to human brain volume variation by regulating proliferation and survival of neural progenitors

scientific article

The role of apolipoprotein E (APOE) genotype in early mild cognitive impairment (E-MCI).

scientific article published on April 2013

Tissue-specific network-based genome wide study of amygdala imaging phenotypes to identify functional interaction modules.

scientific article published on 29 May 2017

Transcriptome-Guided Imaging Genetic Analysis via a Novel Sparse CCA Algorithm

scientific article

Two-dimensional Enrichment Analysis for Mining High-level Imaging Genetic Associations

Two-dimensional enrichment analysis for mining high-level imaging genetic associations

scientific article published on 13 May 2016

Volumetric GWAS of medial temporal lobe structures identifies an ERC1 locus using ADNI high-resolution T2-weighted MRI data

scientific article published on 14 July 2020

Voxel and surface-based topography of memory and executive deficits in mild cognitive impairment and Alzheimer's disease

scientific article

Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation

article

Whole genome association study of brain-wide imaging phenotypes for identifying quantitative trait loci in MCI and AD: A study of the ADNI cohort

scientific article

gene variation and microglial activity on [C]PBR28 PET in older adults at risk for Alzheimer's disease

article

List of works by Kwangsik Nho

18F-florbetapir Positron Emission Tomography-determined Cerebral β-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery

A Graph-Based Integration of Multimodal Brain Imaging Data for the Detection of Early Mild Cognitive Impairment (E-MCI)

APOE Promoter Polymorphism-219T/G is an Effect Modifier of the Influence of APOE ε4 on Alzheimer's Disease Risk in a Multiracial Sample

APOE effect on Alzheimer's disease biomarkers in older adults with significant memory concern

Adult neurogenesis and neurodegenerative diseases: A systems biology perspective

Alpha-synuclein (SNCA) polymorphisms exert protective effects on memory after mild traumatic brain injury

Altered bile acid profile associates with cognitive impairment in Alzheimer's disease-An emerging role for gut microbiome

Altered bile acid profile associates with cognitive impairment in Alzheimer's disease—An emerging role for gut microbiome

Altered bile acid profile in mild cognitive impairment and Alzheimer's disease: Relationship to neuroimaging and CSF biomarkers

Alzheimer's Disease Neuroimaging Initiative biomarkers as quantitative phenotypes: Genetics core aims, progress, and plans

Alzheimer's disease genetic risk variants beyond APOE ε4 predict mortality

Amyloid pathway-based candidate gene analysis of [(11)C]PiB-PET in the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort

Association analysis of rare variants near the APOE region with CSF and neuroimaging biomarkers of Alzheimer's disease

Association of Altered Liver Enzymes With Alzheimer Disease Diagnosis, Cognition, Neuroimaging Measures, and Cerebrospinal Fluid Biomarkers

Association of blood-based transcriptional risk scores with biomarkers for Alzheimer disease

Associations of the Top 20 Alzheimer Disease Risk Variants With Brain Amyloidosis

Automatic Prediction of Conversion from Mild Cognitive Impairment to Probable Alzheimer's Disease using Structural Magnetic Resonance Imaging ⬇️

Bile acids targeted metabolomics and medication classification data in the ADNI1 and ADNIGO/2 cohorts

Brain and blood metabolite signatures of pathology and progression in Alzheimer disease: A targeted metabolomics study.

Brain-wide structural connectivity alterations under the control of Alzheimer risk genes

Broad phenotype of cysteine altering NOTCH3 variants in UK Biobank: CADASIL to non-penetrance

Circulating ethanolamine plasmalogen indices in Alzheimer's disease: Relation to diagnosis, cognition, and CSF tau

Codon bias among synonymous rare variants is associated with Alzheimer's disease imaging biomarker

Common genetic variants influence human subcortical brain structures

Comparing Variability, Severity, and Persistence of Depressive Symptoms as Predictors of Future Stroke Risk

Comparison of Multi-Sample Variant Calling Methods for Whole Genome Sequencing

Comprehensive gene- and pathway-based analysis of depressive symptoms in older adults

Concordant peripheral lipidome signatures in two large clinical studies of Alzheimer's disease

Correction: Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation

Cortical surface biomarkers for predicting cognitive outcomes using group l2,1 norm

Deep Learning in Alzheimer's Disease: Diagnostic Classification and Prognostic Prediction Using Neuroimaging Data

Differential co-expression analysis reveals early stage transcriptomic decoupling in alzheimer's disease

Dysregulated Fc gamma receptor-mediated phagocytosis pathway in Alzheimer's disease: network-based gene expression analysis

Exome Chip Analysis Identifies Low-Frequency a on Brain Magnetic Imaging

From phenotype to genotype: an association study of longitudinal phenotypic markers to Alzheimer's disease relevant SNPs

GWAS of longitudinal amyloid accumulation on 18F-florbetapir PET in Alzheimer's disease implicates microglial activation gene IL1RAP.

Gene-based GWAS and biological pathway analysis of the resilience of executive functioning

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

Genetic Influences on Plasma Homocysteine Levels in African Americans and Yoruba Nigerians

Genetic analysis of quantitative phenotypes in AD and MCI: imaging, cognition and biomarkers

Genetic architecture of resilience of executive functioning

Genetic architecture of subcortical brain structures in 38,851 individuals

Genetic studies of quantitative MCI and AD phenotypes in ADNI: Progress, opportunities, and plans

Genetic variants and functional pathways associated with resilience to Alzheimer's disease

Genetic variation affecting exon skipping contributes to brain structural atrophy in Alzheimer's disease.

Genome-wide association analysis of hippocampal volume identifies enrichment of neurogenesis-related pathways

Genome-wide association study of brain amyloid deposition as measured by Pittsburgh Compound-B (PiB)-PET imaging

Genome-wide association study of language performance in Alzheimer's disease

Genome-wide pathway analysis of memory impairment in the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort implicates gene candidates, canonical pathways, and networks

Genome-wide transcriptome analysis identifies novel dysregulated genes implicated in Alzheimer's pathology

Genomics and CSF analyses implicate thyroid hormone in hippocampal sclerosis of aging

Harnessing peripheral DNA methylation differences in the Alzheimer's Disease Neuroimaging Initiative (ADNI) to reveal novel biomarkers of disease

Hippocampal Sclerosis of Aging, a Common Alzheimer's Disease 'Mimic': Risk Genotypes are Associated with Brain Atrophy Outside the Temporal Lobe

Hippocampal Surface Mapping of Genetic Risk Factors in AD via Sparse Learning Models

Hippocampal transcriptome-guided genetic analysis of correlated episodic memory phenotypes in Alzheimer's disease

IDENTIFICATION OF DISCRIMINATIVE IMAGING PROTEOMICS ASSOCIATIONS IN ALZHEIMER'S DISEASE VIA A NOVEL SPARSE CORRELATION MODEL.

Identification of Novel Genes Associated with Cortical Thickness in Alzheimer's Disease: Systems Biology Approach to Neuroimaging Endophenotype

Identification of common variants associated with human hippocampal and intracranial volumes

Identification of exon skipping events associated with Alzheimer's disease in the human hippocampus

Identification of functionally connected multi-omic biomarkers for Alzheimer's disease using modularity-constrained Lasso

Identifying Neuroimaging and Proteomic Biomarkers for MCI and AD via the Elastic Net

Identifying quantitative trait loci via group-sparse multitask regression and feature selection: an imaging genetics study of the ADNI cohort

Influence of TSPO genotype on 11C-PBR28 standardized uptake values

Influence of genetic variation on plasma protein levels in older adults using a multi-analyte panel

Initiation of antidepressant medication and risk of incident stroke: using the Adult Changes in Thought cohort to address time-varying confounding

Integration of bioinformatics and imaging informatics for identifying rare PSEN1 variants in Alzheimer's disease

Knowledge-driven binning approach for rare variant association analysis: application to neuroimaging biomarkers in Alzheimer's disease

Late-onset Alzheimer's disease, heating up and foxed by several proteins: pathomolecular effects of the aging process.

Longitudinal Genotype-Phenotype Association Study through Temporal Structure Auto-Learning Predictive Model

Longitudinal Genotype-Phenotype Association Study via Temporal Structure Auto-Learning Predictive Model

Metabolic network failures in Alzheimer's disease: A biochemical road map.

MicroRNA-298 reduces levels of human amyloid-β precursor protein (APP), β-site APP-converting enzyme 1 (BACE1) and specific tau protein moieties

MildInt: Deep Learning-Based Multimodal Longitudinal Data Integration Framework

Neuropathological correlates and genetic architecture of microglial activation in elderly human brain

Novel genetic loci associated with hippocampal volume

Novel genetic loci underlying human intracranial volume identified through genome-wide association

Plasma Tau Association with Brain Atrophy in Mild Cognitive Impairment and Alzheimer's Disease

Predicting Alzheimer's disease progression using multi-modal deep learning approach

Progress in Polygenic Composite Scores in Alzheimer's and Other Complex Diseases