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List of works by Toru Komatsu

A Fluorescent Probe for Rapid, High-Contrast Visualization of Folate-Receptor-Expressing Tumors In Vivo

scientific article published on 26 February 2020

A cytosolically localized far-red to near-infrared rhodamine-based fluorescent probe for calcium ions

scientific article published on 01 October 2020

A design strategy for small molecule-based targeted MRI contrast agents: their application for detection of atherosclerotic plaques

scientific article published in November 2014

A method to rapidly induce organelle-specific molecular activities and membrane tethering

scientific article

An Activatable Photosensitizer Targeted to γ-Glutamyltranspeptidase.

scientific article published on 21 June 2017

Antibody Clicking as a Strategy to Modify Antibody Functionalities on the Surface of Targeted Cells

scientific article published on 08 September 2020

Artificial Ligands of Streptavidin (ALiS): Discovery, Characterization, and Application for Reversible Control of Intracellular Protein Transport

scientific article

Boron dipyrromethene as a fluorescent caging group for single-photon uncaging with long-wavelength visible light.

scientific article published on 27 August 2014

Chemical toolbox for 'live' biochemistry to understand enzymatic functions in living systems

scientific article published on 01 February 2020

Design and Synthesis of an Activatable Photoacoustic Probe for Hypochlorous Acid

scientific article published on 02 July 2019

Design of spontaneously blinking fluorophores for live-cell super-resolution imaging based on quantum-chemical calculations

scientific article published on 06 October 2020

Detection of NAD(P)H-dependent enzyme activity by time-domain ratiometry of terbium luminescence.

scientific article published on 11 March 2016

Development and validation of an improved diced electrophoresis gel assay cutter-plate system for enzymomics studies

scientific article published on 19 June 2018

Development of Chemical Tools to Monitor and Control Isoaspartyl Peptide Methyltransferase Activity.

scientific article

Development of a Novel Intraocular-Pressure-Lowering Therapy Targeting ATX

scientific article published on 01 January 2019

Development of a Sensitive Bioluminogenic Probe for Imaging Highly Reactive Oxygen Species in Living Rats

scientific article published on 16 October 2015

Development of a Series of Practical Fluorescent Chemical Tools To Measure pH Values in Living Samples

scientific article published on 24 April 2018

Development of a platform for activatable fluorescent substrates of glucose transporters (GLUTs)

scientific article published on 01 March 2019

Development of a reversible fluorescent probe for reactive sulfur species, sulfane sulfur, and its biological application.

scientific article published on 3 January 2017

Development of an Azo-Based Photosensitizer Activated under Mild Hypoxia for Photodynamic Therapy

scientific article published on 5 September 2017

Development of an Azoreductase-based Reporter System with Synthetic Fluorogenic Substrates.

scientific article

Development of practical red fluorescent probe for cytoplasmic calcium ions with greatly improved cell-membrane permeability.

scientific article published on 8 June 2016

Development of ratiometric carbohydrate sensor based on boron dipyrromethene (BODIPY) scaffold

scientific article published on 13 September 2019

Discovery and Mechanistic Characterization of Selective Inhibitors of H2S-producing Enzyme: 3-Mercaptopyruvate Sulfurtransferase (3MST) Targeting Active-site Cysteine Persulfide

scientific article (publication date: 12 January 2017)

Discovery of Cell-Type-Specific and Disease-Related Enzymatic Activity Changes via Global Evaluation of Peptide Metabolism.

scientific article published on 13 February 2017

Enzyme-Loaded Polyion Complex Vesicles as in Vivo Nanoreactors Working Sustainably under the Blood Circulation: Characterization and Functional Evaluation

scientific article

Establishment of Molecular Design Strategy To Obtain Activatable Fluorescent Probes for Carboxypeptidases.

scientific article

Fluorescence detection of serum albumin with a turnover-based sensor utilizing Kemp elimination reaction.

scientific article published on 26 May 2017

Gliotoxin suppresses NF-κB activation by selectively inhibiting linear ubiquitin chain assembly complex (LUBAC).

scientific article published on 17 December 2014

High-throughput single-molecule bioassay using micro-reactor arrays with a concentration gradient of target molecules

scientific article published on 01 September 2018

ICBS and ECBS Chemical Biology Meeting 2015 - Let Them Come to Berlin!

scientific article published on 01 May 2016

Identification of Lung Inflammation-Related Elevation of Acylamino Acid Releasing Enzyme (APEH) Activity Using an Enzymomics Approach.

scientific article

Metabolic-Pathway-Oriented Screening Targeting S-Adenosyl-l-methionine Reveals the Epigenetic Remodeling Activities of Naturally Occurring Catechols

scientific article published on 23 December 2019

Multiplexed single-molecule enzyme activity analysis for counting disease-related proteins in biological samples

scientific article published on 11 March 2020

New class of bioluminogenic probe based on bioluminescent enzyme-induced electron transfer: BioLeT.

scientific article published on 19 March 2015

Potential of Enzymomics Methodologies to Characterize Disease-Related Protein Functions.

scientific article

Rapid and sensitive detection of early esophageal squamous cell carcinoma with fluorescence probe targeting dipeptidylpeptidase IV

scientific article

Rapid detection of metastatic lymph nodes of colorectal cancer with a gamma-glutamyl transpeptidase-activatable fluorescence probe

scientific article published in Scientific Reports

Rapidly rendering cells phagocytic through a cell surface display technique and concurrent Rac activation

scientific article

Rational Design of a Near-infrared Fluorescence Probe for Ca2+ Based on Phosphorus-substituted Rhodamines Utilizing Photoinduced Electron Transfer

scientific article published on 28 January 2020

Rational design of boron dipyrromethene (BODIPY)-based photobleaching-resistant fluorophores applicable to a protein dynamics study ⬇️

scientific article published on August 5, 2011

Red Fluorescence Probe Targeted to Dipeptidylpeptidase-IV for Highly Sensitive Detection of Esophageal Cancer

scientific article published on 03 April 2019

Red Fluorescent Probe for Monitoring the Dynamics of Cytoplasmic Calcium Ions ⬇️

scientific article published on February 25, 2013

Red-Shifted Fluorogenic Substrate for Detection of lacZ-Positive Cells in Living Tissue with Single-Cell Resolution

scientific article published on 02 November 2018

Reversible Off–On Fluorescence Probe for Hypoxia and Imaging of Hypoxia–Normoxia Cycles in Live Cells ⬇️

scientific article published on November 26, 2012

Selective ablation of β-galactosidase-expressing cells with a rationally designed activatable photosensitizer.

scientific article

Separation-Based Enzymomics Assay for the Discovery of Altered Peptide-Metabolizing Enzymatic Activities in Biosamples

scientific article published on 23 August 2019

Synthesis of practical red fluorescent probe for cytoplasmic calcium ions with greatly improved cell-membrane permeability

scientific article published on 13 April 2017

Synthesis of unsymmetrical Si-rhodamine fluorophores and application to a far-red to near-infrared fluorescence probe for hypoxia

scientific article published on 01 June 2018

Thermal or mechanical stimuli-induced photoluminescence color change of a molecular assembly composed of an amphiphilic anthracene derivative in water

scientific article published on 9 July 2014

Unexpected Photo-instability of 2,6-Sulfonamide-Substituted BODIPYs and Its Application to Caged GABA.

scientific article published on 2 April 2016

[Challenges of Young Chemists to Be Global]

scientific article published on 01 January 2019

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