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List of works by Feilim Mac Gabhann

A compartment model of VEGF distribution in blood, healthy and diseased tissues.

scientific article

A compartment model of VEGF distribution in humans in the presence of soluble VEGF receptor-1 acting as a ligand trap

scientific article

A computational analysis of in vivo VEGFR activation by multiple co-expressed ligands.

scientific article

A systems biology perspective on sVEGFR1: its biological function, pathogenic role and therapeutic use.

scientific article published on 16 October 2009

A systems biology view of blood vessel growth and remodelling

scientific article

APOBEC3G-Augmented Stem Cell Therapy to Modulate HIV Replication: A Computational Study ⬇️

scientific article published on May 22, 2013

Advancing code sharing in the computational biology community

scientific article published on 02 June 2022

Agent-based computational model of retinal angiogenesis simulates microvascular network morphology as a function of pericyte coverage.

scientific article published on 8 August 2017

Agent-based model of angiogenesis simulates capillary sprout initiation in multicellular networks

scientific article

Applications of computational models to better understand microvascular remodelling: a focus on biomechanical integration across scales.

scientific article

Arterialized collateral capillaries progress from non-reactive to capable of increasing perfusion in an ischemic tree

scientific article published on 28 December 2017

Brain Macrophages in Simian Immunodeficiency Virus-Infected, Antiretroviral-Suppressed Macaques: a Functional Latent Reservoir

scientific article published on 15 August 2017

Collateral capillary arterialization following arteriolar ligation in murine skeletal muscle

scientific article

Computational Model of Gab1/2-Dependent VEGFR2 Pathway to Akt Activation.

scientific article

Computational Systems Biochemistry: Beyond the Static Interactome.

scientific article published on 8 December 2017

Computational kinetic model of VEGF trapping by soluble VEGF receptor-1: effects of transendothelial and lymphatic macromolecular transport

scientific article

Computational model of VEGFR2 pathway to ERK activation and modulation through receptor trafficking.

scientific article published on 29 August 2013

Computational model of vascular endothelial growth factor spatial distribution in muscle and pro-angiogenic cell therapy

scientific article published on 3 August 2006

Computational modeling of interacting VEGF and soluble VEGF receptor concentration gradients.

scientific article

Computational models of VEGF-associated angiogenic processes in cancer

scientific article published on 25 January 2011

Context-dependent regulation of receptor tyrosine kinases: Insights from systems biology approaches

scientific article published on 26 September 2018

Differential binding of VEGF isoforms to VEGF receptor 2 in the presence of neuropilin-1: a computational model

scientific article

Dimerization of VEGF receptors and implications for signal transduction: a computational study

scientific article

Divide and conquer, faster: speeding up molecular simulations

scientific article published on February 2015

Dysregulation of the vascular endothelial growth factor and semaphorin ligand-receptor families in prostate cancer metastasis

scientific article published on 4 September 2015

Effects of Fiber Type and Size on the Heterogeneity of Oxygen Distribution in Exercising Skeletal Muscle ⬇️

scientific article published on September 18, 2012

Endothelial cell-dependent regulation of arteriogenesis

scientific article

Expression of VEGF and Semaphorin Genes Define Subgroups of Triple Negative Breast Cancer ⬇️

scientific article published on May 8, 2013

Extracellular regulation of VEGF: isoforms, proteolysis, and vascular patterning.

scientific article

Flt-1 (VEGFR-1) coordinates discrete stages of blood vessel formation

scientific article

Formation of VEGF isoform-specific spatial distributions governing angiogenesis: computational analysis ⬇️

scientific article

Further Support for ECM Control of Receptor Trafficking and Signaling.

scientific article published on 20 June 2016

Gene therapy from the perspective of systems biology ⬇️

scientific article published on October 1, 2010

Improving reproducibility in computational biology research

scientific article published on 19 May 2020

Increase of plasma VEGF after intravenous administration of bevacizumab is predicted by a pharmacokinetic model

scientific article published on 30 November 2010

Integration of experimental and computational approaches to sprouting angiogenesis.

scientific article

Interactions of VEGF isoforms with VEGFR-1, VEGFR-2, and neuropilin in vivo: a computational model of human skeletal muscle

scientific article published on 15 September 2006

Mechanistic Models Predict Efficacy of CCR5-Deficient Stem Cell Transplants in HIV Patient Populations

scientific article published on 16 February 2016

Model of competitive binding of vascular endothelial growth factor and placental growth factor to VEGF receptors on endothelial cells ⬇️

scientific article published on April 24, 2003

Modeling of growth factor-receptor systems from molecular-level protein interaction networks to whole-body compartment models

scientific article published on January 2009

Module-based multiscale simulation of angiogenesis in skeletal muscle

scientific article

Molecular mechanism matters: Benefits of mechanistic computational models for drug development.

scientific article

Monte Carlo simulations of VEGF binding to cell surface receptors in vitro

scientific article published on 5 October 2005

Multi-scale computational models of pro-angiogenic treatments in peripheral arterial disease

scientific article published on 10 April 2007

Multi-scale modeling of HIV infection in vitro and APOBEC3G-based anti-retroviral therapy

scientific article

Multiplexed Component Analysis to Identify Genes Contributing to the Immune Response during Acute SIV Infection

scientific article published on 18 May 2015

Multiscale models of angiogenesis

scientific article

Murine spinotrapezius model to assess the impact of arteriolar ligation on microvascular function and remodeling.

scientific article

Myeloid and CD4 T Cells Comprise the Latent Reservoir in Antiretroviral Therapy-Suppressed SIVmac251-Infected Macaques

scientific article published on 20 August 2019

Protein transport to choroid and retina following periocular injection: theoretical and experimental study

scientific article published on 3 February 2007

Quantifying the proteolytic release of extracellular matrix-sequestered VEGF with a computational model

scientific article

Selective Activation of Sphingosine 1-Phosphate Receptors 1 and 3 Promotes Local Microvascular Network Growth ⬇️

scientific article published on November 9, 2010

Signaling Network Map of Endothelial TEK Tyrosine Kinase.

scientific article

Site-Specific Phosphorylation of VEGFR2 Is Mediated by Receptor Trafficking: Insights from a Computational Model

scientific article published on 12 June 2015

Skeletal muscle VEGF gradients in peripheral arterial disease: simulations of rest and exercise

scientific article published on 21 September 2007

Systems Pharmacology of VEGF165b in Peripheral Artery Disease

scientific article published on 28 November 2017

Systems analysis of small signaling modules relevant to eight human diseases

scientific article

Systems biology of pro-angiogenic therapies targeting the VEGF system

scientific article

Systems biology of the microvasculature

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Systems biology of vascular endothelial growth factors

scientific article

TILRR Steers Interleukin-1 Signaling: Co-Receptor Provides Context and a Therapeutic Target

scientific article published on 28 August 2017

Targeting neuropilin-1 to inhibit VEGF signaling in cancer: Comparison of therapeutic approaches

scientific article

The blossoming of methods and software in computational biology

scientific article published on 17 August 2023

The presence of VEGF receptors on the luminal surface of endothelial cells affects VEGF distribution and VEGF signaling

scientific article

Trans-scleral delivery of antiangiogenic proteins

scientific article published in February 2008

Tumor and endothelial cells collaborate via transcellular receptor complexes

scientific article published on 29 November 2018

VEGF and soluble VEGF receptor-1 (sFlt-1) distributions in peripheral arterial disease: an in silico model

scientific article

VEGF gradients, receptor activation, and sprout guidance in resting and exercising skeletal muscle

scientific article published on 12 October 2006

VEGF-A121a binding to Neuropilins - A concept revisited.

scientific article published on 2 November 2017

Vascular morphogenesis of adipose-derived stem cells is mediated by heterotypic cell-cell interactions

scientific article

Where is VEGF in the body? A meta-analysis of VEGF distribution in cancer.

scientific article published on 2 October 2007

Wisdom of crowds in computational biology.

scientific article published on 23 May 2019

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