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List of works by Crispin R Dass

A Method for Intratumoral Continuous Infusion of Antisense Oligodeoxynucleotides ⬇️

scientific article published on 01 March 1998

A chitosan hydrogel delivery system for osteosarcoma gene therapy with pigment epithelium-derived factor combined with chemotherapy.

scientific article

A chitosan-dipotassium orthophosphate hydrogel for the delivery of Doxorubicin in the treatment of osteosarcoma.

scientific article published on 5 April 2009

A nanoparticulate system that enhances the efficacy of the tumoricide Dz13 when administered proximal to the lesion site

scientific article published on 15 January 2010

A novel orthotopic murine model provides insights into cellular and molecular characteristics contributing to human osteosarcoma.

scientific article published on 23 December 2006

Anti-chondrosarcoma effects of PEDF mediated via molecules important to apoptosis, cell cycling, adhesion and invasion.

scientific article

Bim-targeted cancer therapy: a link between drug action and underlying molecular changes.

scientific article published on December 2009

Biocompatible chitosan-DNAzyme nanoparticle exhibits enhanced biological activity

scientific article published on 01 September 2008

C2C12 cell model: its role in understanding of insulin resistance at the molecular level and pharmaceutical development at the preclinical stage

scientific article published on 18 August 2020

Cancer cell apoptotic pathways mediated by PEDF: prospects for therapy.

scientific article published on 25 September 2009

Cancer, chitosan nanoparticles and catalytic nucleic acids.

scientific article published on January 2009

Carrier-mediated delivery of peptidic drugs for cancer therapy.

scientific article published on 21 June 2006

Cell and Molecular Biology Underpinning the Effects of PEDF on Cancers in General and Osteosarcoma in Particular ⬇️

scientific article published on May 28, 2012

Cellular assays and applied technologies for characterisation of orally administered protein nanoparticles: a systematic review

scientific article published on 12 February 2020

Chitosan microparticles encapsulating PEDF plasmid demonstrate efficacy in an orthotopic metastatic model of osteosarcoma.

scientific article published on 18 March 2007

Chitosan-mediated orally delivered nucleic acids: a gutful of gene therapy.

scientific article published on May 2008

Commonly used mouse models of osteosarcoma.

scientific article published on 11 July 2006

Current status and applications of animal models in pre-clinical development of orally administered insulin-loaded nanoparticles

scientific article published on 20 April 2020

DNAzyme delivery systems: getting past first base

scientific article published on 01 February 2009

DNAzyme technology and cancer therapy: cleave and let die.

scientific article published on February 2008

Delivery of therapeutics for deep-seated ocular conditions - status quo.

scientific article published on 19 April 2018

Development of orally administered insulin-loaded polymeric-oligonucleotide nanoparticles: statistical optimization and physicochemical characterization

scientific article published on 28 June 2020

Direct anti-metastatic efficacy by the DNA enzyme Dz13 and downregulated MMP-2, MMP-9 and MT1-MMP in tumours.

scientific article

Downregulation of c-jun results in apoptosis-mediated anti-osteosarcoma activity in an orthotopic model.

scientific article

Downregulation of uPAR confirms link in growth and metastasis of osteosarcoma

scientific article published on 01 January 2005

Doxorubicin, mesenchymal stem cell toxicity and antitumour activity: implications for clinical use.

scientific article

Dz13 induces a cytotoxic stress response with upregulation of E2F1 in tumor cells metastasizing to or from bone.

scientific article published on April 2010

Dz13, a c-jun DNAzyme, is a potent inducer of caspase-2 activation.

scientific article published on June 2010

Dz13: c‐Jun Downregulation and Tumour Cell Death ⬇️

scientific article published on October 31, 2011

Enhanced Anticancer Therapy Mediated by Specialized Liposomes ⬇️

scientific article published on October 1, 1997

Fabrication techniques for the preparation of orally administered insulin nanoparticles

scientific article published on 02 September 2020

GFP expression alters osteosarcoma cell biology.

scientific article published on August 2007

Gene therapy for osteosarcoma: steps towards clinical studies.

scientific article published on April 2008

Human xenograft osteosarcoma models with spontaneous metastasis in mice: clinical relevance and applicability for drug testing.

scientific article published on 10 October 2006

In vitro and in vivo biological activity of PEDF against a range of tumors.

scientific article published on December 2009

Induction of Caspase-2 Activation by a DNA Enzyme Evokes Tumor Cell Apoptosis ⬇️

scientific article published on November 11, 2011

Methods for co-culturing tumour and endothelial cells: systems and their applications ⬇️

scientific article published on September 19, 2011

Microarray: an instrument for cancer surgeons of the future?

scientific article published on July 2010

Netrin-1 in the developing enteric nervous system and colorectal cancer ⬇️

scientific article published on August 21, 2012

New clinically relevant, orthotopic mouse models of human chondrosarcoma with spontaneous metastasis

scientific article

Novel therapeutic strategy for osteosarcoma targeting osteoclast differentiation, bone-resorbing activity, and apoptosis pathway.

scientific article

Oral insulin delivery: existing barriers and current counter-strategies

scientific article published on 28 November 2017

Osteosarcoma treatment: state of the art.

scientific article published on June 2009

PEDF as an emerging therapeutic candidate for osteosarcoma.

scientific article published on December 2008

PEDF regulates osteoclasts via osteoprotegerin and RANKL

scientific article published on 27 November 2009

PEDF-derived synthetic peptides exhibit antitumor activity in an orthotopic model of human osteosarcoma.

scientific article

PEDF: a potential molecular therapeutic target with multiple anti-cancer activities.

scientific article published on 7 September 2006

Pigment Epithelium-Derived Factor: Chemistry, Structure, Biology, and Applications ⬇️

scientific article published on September 5, 2012

Pigment epithelium-derived factor as an anticancer drug and new treatment methods following the discovery of its receptors: a patent perspective ⬇️

scientific article published on January 5, 2011

Pigment epithelium-derived factor as an impending therapeutic agent against vascular epithelial growth factor-driven tumor-angiogenesis.

scientific article published on 10 December 2010

Pigment epithelium-derived factor: a key mediator in bone homeostasis and potential for bone regenerative therapy

scientific article published on 05 July 2018

RECK in osteosarcoma: a novel role in tumour vasculature and inhibition of tumorigenesis in an orthotopic model

scientific article published on 01 February 2011

Review: doxorubicin delivery systems based on chitosan for cancer therapy.

scientific article published on February 2009

Selective gene delivery for cancer therapy using cationic liposomes: in vivo proof of applicability.

scientific article published on 9 May 2006

Systemically administered PEDF against primary and secondary tumours in a clinically relevant osteosarcoma model ⬇️

scientific article published on October 6, 2011

Targeting of small molecule anticancer drugs to the tumour and its vasculature using cationic liposomes: lessons from gene therapy.

scientific article published on 23 June 2006

The Emerging Role of PEDF in Stem Cell Biology ⬇️

scientific article published on May 17, 2012

The Reciprocal Interaction: Chemotherapy and Tumor Microenvironment ⬇️

scientific article published on June 1, 2011

The molecular pathogenesis of osteosarcoma: a review

scientific article

The role of chitosan on oral delivery of peptide-loaded nanoparticle formulation

scientific article published on 2 November 2017

The role of pigment epithelium-derived factor in protecting against cellular stress

scientific article published on 06 December 2019

The use of chitosan formulations in cancer therapy

scientific article published on 01 June 2008

Therapeutic targeting of osteoclast function and pathways.

scientific article published on 05 January 2011

Transdifferentiation of adipocytes to osteoblasts: potential for orthopaedic treatment.

scientific article

Transdifferentiation of myoblasts into osteoblasts - possible use for bone therapy

scientific article published on 15 August 2017

Weak bones in diabetes mellitus - an update on pharmaceutical treatment options

scientific article published on 5 September 2017

c-Jun Is critical for the progression of osteosarcoma: proof in an orthotopic spontaneously metastasizing model.

scientific article

c-Jun knockdown sensitizes osteosarcoma to doxorubicin.

scientific article published in July 2008

uPAR mediates anticancer activity of PEDF.

scientific article

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