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List of works by Isidro Ferrer

"Lipid raft aging" in the human frontal cortex during nonpathological aging: gender influences and potential implications in Alzheimer's disease

scientific article

"Preclinical" MSA in definite Creutzfeldt-Jakob disease.

scientific article published on 21 June 2011

(Patho-)physiological relevance of PINK1-dependent ubiquitin phosphorylation

scientific article

A DNA methylation fingerprint of 1628 human samples

scientific article

A highly expressed miR-101 isomiR is a functional silencing small RNA

scientific article

A myriad of miRNA variants in control and Huntington's disease brain regions detected by massively parallel sequencing

scientific article

A new tetra-plex fluorimetric assay for the quantification of cerebrospinal fluid β-amyloid42, total-tau, phospho-tau and α-synuclein in the differential diagnosis of neurodegenerative dementia

scientific article published on 05 May 2020

A novel PRNP Y218N mutation in Gerstmann-Sträussler-Scheinker disease with neurofibrillary degeneration.

scientific article published on August 2010

A pathogenic mechanism in Huntington's disease involves small CAG-repeated RNAs with neurotoxic activity.

scientific article

A preliminary study of the whole-genome expression profile of sporadic and monogenic early-onset Alzheimer's disease

scientific article published on 28 January 2013

A1 Adenosine Receptors Accumulate in Neurodegenerative Structures in Alzheimer's Disease and Mediate Both Amyloid Precursor Protein Processing and Tau Phosphorylation and Translocation

scholarly article by Ester Angulo et al published 5 April 2006 in Brain Pathology

A1 adenosine receptors accumulate in neurodegenerative structures in Alzheimer disease and mediate both amyloid precursor protein processing and tau phosphorylation and translocation

scientific article published on October 2003

Aberrant regulation of the GSK-3β/NRF2 axis unveils a novel therapy for adrenoleukodystrophy

scientific article published on 01 August 2018

Abnormal alpha-synuclein solubility, aggregation and nitration in the frontal cortex in Pick's disease

scientific article published on 3 March 2006

Activation of ataxia telangiectasia muted under experimental models and human Parkinson's disease

scientific journal article

Activation of the calpain/cdk5/p25 pathway in the girus cinguli in Parkinson's disease.

scientific article published on 31 October 2007

Active stress kinase p38 enhances and perpetuates abnormal tau phosphorylation and deposition in Pick's disease

scientific article published on 20 December 2003

Acute clinical onset chronic inflammatory demyelinating polyneuropathy in a dog

Adenosine A1 receptor protein levels and activity is increased in the cerebral cortex in Creutzfeldt-Jakob disease and in bovine spongiform encephalopathy-infected bovine-PrP mice

scientific article published in October 2006

Adenosine A2A-Cannabinoid CB1 Receptor Heteromers in the Hippocampus: Cannabidiol Blunts Δ9-Tetrahydrocannabinol-Induced Cognitive Impairment

scientific article published on 04 January 2019

Age- and disease-dependent increase of the mitophagy marker phospho-ubiquitin in normal aging and Lewy body disease

scientific article published on 28 July 2018

Age-Related Changes in Lipidome of Rat Frontal Cortex and Cerebellum Are Partially Reversed by Methionine Restriction Applied in Old Age

scientific article published in 2021

Aging dependent effect of nuclear tau.

scientific article published on 30 September 2017

Aging-related tau astrogliopathy (ARTAG): Not only tau phosphorylation in astrocytes.

scientific article

Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy

scientific article published on 10 December 2015

Altered CSNK1E, FABP4 and NEFH protein levels in the dorsolateral prefrontal cortex in schizophrenia

scientific article published on 25 May 2016

Altered Ca2+ homeostasis induces Calpain-Cathepsin axis activation in sporadic Creutzfeldt-Jakob disease

scientific article

Altered Machinery of Protein Synthesis in Alzheimer's: From the Nucleolus to the Ribosome.

scientific article published on 29 October 2015

Altered Mitochondrial DNA Methylation Pattern in Alzheimer Disease-Related Pathology and in Parkinson Disease

scientific article published in February 2016

Altered distribution of RhoA in Alzheimer's disease and AbetaPP overexpressing mice.

scientific article published in January 2010

Altered gene transcription linked to astrocytes and oligodendrocytes in frontal cortex in Creutzfeldt-Jakob disease

scientific article published on 27 July 2018

Altered lipid composition in cortical lipid rafts occurs at early stages of sporadic Alzheimer's disease and facilitates APP/BACE1 interactions.

scientific article published on 11 February 2014

Altered machinery of protein synthesis is region- and stage-dependent and is associated with α-synuclein oligomers in Parkinson's disease.

scientific article

Altered mitochondria, energy metabolism, voltage-dependent anion channel, and lipid rafts converge to exhaust neurons in Alzheimer's disease

scientific article published on October 2009

Amyloid generation and dysfunctional immunoproteasome activation with disease progression in animal model of familial Alzheimer's disease

scientific article published on 13 January 2012

Amyloid-targeted therapeutics in Alzheimer's disease: use of human albumin in plasma exchange as a novel approach for Abeta mobilization.

scientific article published on July 2009

Amyloid-β Precursor Protein Modulates the Sorting of Testican-1 and Contributes to Its Accumulation in Brain Tissue and Cerebrospinal Fluid from Patients with Alzheimer Disease

scientific article published on 02 August 2016

Amyotrophic Lateral Sclerosis Is Accompanied by Protein Derangements in the Olfactory Bulb-Tract Axis

scientific article published on 05 November 2020

Analysis of Sp transcription factors in the postmortem brain of chronic schizophrenia: a pilot study of relationship to negative symptoms.

scientific article published on 27 March 2013

Anatomical distribution of lipids in human brain cortex by imaging mass spectrometry.

scientific article

Anatomical location of LPA1 activation and LPA phospholipid precursors in rodent and human brain.

scientific article published on 27 April 2015

Annexin A5 prevents amyloid-β-induced toxicity in choroid plexus: implication for Alzheimer's disease

scientific article published on 10 June 2020

Anomalies occurring in lipid profiles and protein distribution in frontal cortex lipid rafts in dementia with Lewy bodies disclose neurochemical traits partially shared by Alzheimer's and Parkinson's diseases.

scientific article published on 6 September 2016

Antioxidants halt axonal degeneration in a mouse model of X-adrenoleukodystrophy.

scientific article

Aprosodic speech with insular hyperintensities and 4R Tau pathology on autopsy ⬇️

scientific article published on September 20, 2012

Aquaporin 1 and aquaporin 4 overexpression in bovine spongiform encephalopathy in a transgenic murine model and in cattle field cases

scientific article published on 27 July 2007

Aquaporin expression in the cerebral cortex is increased at early stages of Alzheimer disease

scientific article published on 22 November 2006

Assessment of Glial Activation Response in the Progress of Natural Scrapie after Chronic Dexamethasone Treatment

scientific article published on 02 May 2020

Atypical neuropathological sCJD-MM phenotype with abundant white matter Kuru-type plaques sparing the cerebellar cortex

scientific article published on 6 August 2012

Autophagy induction halts axonal degeneration in a mouse model of X-adrenoleukodystrophy.

scientific article

Biophysical alterations in lipid rafts from human cerebral cortex associate with increased BACE1/AβPP interaction in early stages of Alzheimer's disease.

scientific article published in January 2015

Brain banks: benefits, limitations and cautions concerning the use of post-mortem brain tissue for molecular studies

scientific article published on 10 June 2008

Brain protein preservation largely depends on the postmortem storage temperature: implications for study of proteins in human neurologic diseases and management of brain banks: a BrainNet Europe Study

scientific article published in January 2007

Brainstem dysgenesis: report of five patients with congenital hypotonia, multiple cranial nerve involvement, and ocular motor apraxia.

scientific article

Calcium-binding proteins are altered in the cerebellum in schizophrenia

scientific article published on 08 July 2020

Cannabidiol-Enriched Extract Reduced the Cognitive Impairment but Not the Epileptic Seizures in a Lafora Disease Animal Model

scientific article published on 05 June 2020

Cannabinoid Receptor 2 Participates in Amyloid-β Processing in a Mouse Model of Alzheimer's Disease but Plays a Minor Role in the Therapeutic Properties of a Cannabis-Based Medicine.

scientific article published on 6 February 2016

Cannabinoid pharmacology/therapeutics in chronic degenerative disorders affecting the central nervous system

scientific article published on 17 August 2018

Cannabinoids for treatment of Alzheimer's disease: moving toward the clinic.

scientific article published on 05 March 2014

Cell cycle activation in striatal neurons from Huntington's disease patients and rats treated with 3-nitropropionic acid

scientific article published on 12 August 2008

Central apnea in a sporadic case of Creutzfeldt-Jakob disease with brainstem involvement.

scientific article

Central nervous system extracellular matrix changes in a transgenic mouse model of bovine spongiform encephalopathy

scientific article published on 12 September 2008

Centrally Active Multitarget Anti-Alzheimer Agents Derived from the Antioxidant Lead CR-6

scientific article published on 24 July 2020

Cerebrospinal Fluid Total Prion Protein in the Spectrum of Prion Diseases

scientific article published on 30 July 2018

Cerebrospinal fluid lipocalin 2 as a novel biomarker for the differential diagnosis of vascular dementia

scientific article published on 30 January 2020

Cerebrospinal fluid neurofilament light levels in neurodegenerative dementia: Evaluation of diagnostic accuracy in the differential diagnosis of prion diseases

scientific article

Characterization of Thorn‐Shaped Astrocytes in White Matter of Temporal Lobe in Alzheimer's Disease Brains ⬇️

scientific article published on September 13, 2012

Choline acetyltransferase expression does not identify early pathogenic events in fetal SMA spinal cord

scientific article published on 28 January 2005

Chorea-ballism associated with familial amyotrophic lateral sclerosis. A clinical, genetic, and neuropathological study

scientific article

Clinical and Pathological Heterogeneity of Neuronal Intermediate Filament Inclusion Disease

Clinical and myopathological evaluation of early- and late-onset subtypes of myofibrillar myopathy

scientific article published on 14 June 2011

Clinical correlations with Lewy body pathology in LRRK2-related Parkinson disease

scientific article

Clinical, neuropathologic, and biochemical profile of the amyloid precursor protein I716F mutation

scientific article published in January 2010

Cognitive impairment of vascular origin: Neuropathology of cognitive impairment of vascular origin ⬇️

scientific article published on September 16, 2010

Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions

scientific article

Complex Inflammation mRNA-Related Response in ALS Is Region Dependent

scientific article

Complex deregulation and expression of cytokines and mediators of the immune response in Parkinson's disease brain is region dependent

scientific article

Consensus classification of human prion disease histotypes allows reliable identification of molecular subtypes: an inter-rater study among surveillance centres in Europe and USA

scientific article published on 30 June 2012

CpG and non-CpG Presenilin1 methylation pattern in course of neurodevelopment and neurodegeneration is associated with gene expression in human and murine brain

scientific article published on 05 February 2020

Creutzfeldt-Jakob Disease Subtype-Specific Regional and Temporal Regulation of ADP Ribosylation Factor-1-Dependent Rho/MLC Pathway at Pre-Clinical Stage.

scientific article published on 21 April 2015

Cryptic exon splicing function of TARDBP interacts with autophagy in nervous tissue

scientific article published on 28 July 2018

Cyclophilin D as a potential target for antioxidants in neurodegeneration: the X-ALD case.

scientific article published on May 2013

Cytoskeleton-Associated Risk Modifiers Involved in Early and Rapid Progression of Sporadic Creutzfeldt-Jakob Disease

scientific article published in June 2017

DNA Methylation Profiles of Selected Pro-Inflammatory Cytokines in Alzheimer Disease

scientific article published on 4 January 2017

DNA methylation and Yin Yang‐1 repress adenosine A2A receptor levels in human brain ⬇️

scientific article published on August 19, 2010

DNA methylation map of mouse and human brain identifies target genes in Alzheimer's disease.

scientific article published on 11 September 2013

DNA methylation of Alzheimer disease and tauopathy-related genes in postmortem brain

scientific article published in August 2009

DNA methylation regulates adenosine A(2A) receptor cell surface expression levels.

scientific article

DYRK1A-mediated phosphorylation of GluN2A at Ser(1048) regulates the surface expression and channel activity of GluN1/GluN2A receptors

scientific article

Decrease in olfactory and taste receptor expression in the dorsolateral prefrontal cortex in chronic schizophrenia.

scientific article published on 2 October 2014

Delineation of Early Changes in Cases with Progressive Supranuclear Palsy-Like Pathology. Astrocytes in Striatum are Primary Targets of Tau Phosphorylation and GFAP Oxidation

scientific article published on 06 May 2008

Dense core vesicle markers in CSF and cortical tissues of patients with Alzheimer's disease

scientific article published on 26 September 2021

Depletion of oxidative and endoplasmic reticulum stress regulators in Pick disease

scientific article

Deposition of hyperphosphorylated tau in cerebellum of PS1 E280A Alzheimer's disease

scientific article published on 27 January 2011

Deregulation of purine metabolism in Alzheimer's disease

scientific article published on 8 August 2014

Diagnostic Accuracy of Prion Disease Biomarkers in Iatrogenic Creutzfeldt-Jakob Disease

scientific article published on 12 February 2020

Dietary Lipid Unsaturation Influences Survival and Oxidative Modifications of an Amyotrophic Lateral Sclerosis Model in a Gender-Specific Manner

scientific article published on 01 July 2014

Differences in structure and function between human and murine tau

scientific article published on 12 August 2018

Disclosing bias in bisulfite assay: MethPrimers underestimate high DNA methylation

scientific article

Disrupted functional connectivity of the locus coeruleus in healthy adults with parental history of Alzheimer's disease

scientific article published on 30 January 2020

Disrupting MLC1 and GlialCAM and ClC-2 interactions in leukodystrophy entails glial chloride channel dysfunction

scientific article published on 19 March 2014

Distinct patterns of APP processing in the CNS in autosomal-dominant and sporadic Alzheimer disease

scientific article published on 6 December 2012

Dopamine induces autophagic cell death and alpha-synuclein increase in human neuroblastoma SH-SY5Y cells

scientific article published in August 2003

Dysregulated protein phosphorylation: A determining condition in the continuum of brain aging and Alzheimer's disease

scientific article published on 04 July 2021

Dystrophic neurites of senile plaques in Alzheimer's disease are deficient in cytochrome c oxidase

scientific article published on 16 July 2008

Early alpha-synuclein lipoxidation in neocortex in Lewy body diseases

scientific article published on 12 December 2006

Early and gender-specific differences in spinal cord mitochondrial function and oxidative stress markers in a mouse model of ALS

scientific article published on 13 January 2016

Early involvement of the cerebral cortex in Parkinson's disease: convergence of multiple metabolic defects

scientific article published on 09 March 2009

Early oxidative damage underlying neurodegeneration in X-adrenoleukodystrophy

scientific article

Early-onset familial lewy body dementia with extensive tauopathy: a clinical, genetic, and neuropathological study.

scientific article

Effects of formalin fixation, paraffin embedding, and time of storage on DNA preservation in brain tissue: a BrainNet Europe study

scientific article published on 23 April 2007

Efficacy and Safety of Plasma Exchange with 5% Albumin to Modify Cerebrospinal Fluid and Plasma Amyloid-β Concentrations and Cognition Outcomes in Alzheimer's Disease Patients: A Multicenter, Randomized, Controlled Clinical Trial

scientific article

Estudio de la vulnerabilidad neuronal selectiva en el sistema nervioso central humano

scientific article published on 05 September 2013

Evidence of oxidative stress in the neocortex in incidental Lewy body disease

scientific article

Excitotoxic inactivation of constitutive oxidative stress detoxification pathway in neurons can be rescued by PKD1.

scientific article published on 22 December 2017

Expression of transcription factors c-Fos, c-Jun, CREB-1 and ATF-2, and caspase-3 in relation with abnormal tau deposits in Pick's disease

scientific article published on 23 February 2006

FUS immunogold labeling TEM analysis of the neuronal cytoplasmic inclusions of neuronal intermediate filament inclusion disease: a frontotemporal lobar degeneration with FUS proteinopathy

scientific article

Familial behavioral variant frontotemporal dementia associated with astrocyte-predominant tauopathy

scientific article

Familial globular glial tauopathy linked to MAPT mutations: molecular neuropathology and seeding capacity of a prototypical mixed neuronal and glial tauopathy

scientific article published on 06 January 2020

Functional genomics reveals dysregulation of cortical olfactory receptors in Parkinson disease: novel putative chemoreceptors in the human brain

scientific article

Functional overlap between ABCD1 (ALD) and ABCD2 (ALDR) transporters: a therapeutic target for X-adrenoleukodystrophy

scientific article published on 15 October 2004

GSK3β 5'-flanking DNA Methylation and Expression in Alzheimer's Disease Patients.

scientific article

Gender-Specific Beneficial Effects of Docosahexaenoic Acid Dietary Supplementation in G93A-SOD1 Amyotrophic Lateral Sclerosis Mice

scientific article published on 01 January 2020

Gene expression profile in JNK3 null mice: a novel specific activation of the PI3K/AKT pathway.

scientific article published on 24 February 2011

Gene expression resulting from PrPC ablation and PrPC overexpression in murine and cellular models

scientific article published on 16 August 2013

Genealogy of the neurodegenerative diseases based on a meta-analysis of age-stratified incidence data

scientific article published on 03 November 2020

Generalized muscle pseudo-hypertrophy and stiffness associated with the myotilin Ser55Phe mutation: a novel myotilinopathy phenotype?

scientific article

Genetic and Transcriptomic Profiles of Inflammation in Neurodegenerative Diseases: Alzheimer, Parkinson, Creutzfeldt-Jakob and Tauopathies

scientific article

Genetic deletion of CB1 cannabinoid receptors exacerbates the Alzheimer-like symptoms in a transgenic animal model

scientific article published on 07 August 2018

Glial and neuronal tau pathology in tauopathies: characterization of disease-specific phenotypes and tau pathology progression

scientific article published in January 2014

Group I mGluR signaling in BSE-infected bovine-PrP transgenic mice

scientific article published on 7 November 2006

Hemoglobin mRNA Changes in the Frontal Cortex of Patients with Neurodegenerative Diseases

scientific article published on 22 January 2018

Hereditary Human Prion Diseases: an Update

scientific article published on 20 June 2016

High-dose biotin restores redox balance, energy and lipid homeostasis, and axonal health in a model of adrenoleukodystrophy

scientific article published on 08 June 2020

Hippocampal Damage During Mechanical Ventilation in Trendelenburg Position: A Secondary Analysis of an Experimental Study on the Prevention of Ventilator-Associated Pneumonia

scientific article published on 01 July 2019

Hippocampal Radial Glial Subtypes and Their Neurogenic Potential in Human Fetuses and Healthy and Alzheimer's Disease Adults

scientific article published on 2 May 2018

Histone tail acetylation in brain occurs in an unpredictable fashion after death

scientific article published on 16 September 2011

Historical setting and neuropathology of lathyrism: Insights from the neglected 1944 report by Oliveras de la Riva

scientific article published on 03 July 2019

Huntington's disease is a four-repeat tauopathy with tau nuclear rods.

scientific article published on 20 July 2014

Hypothesis review: Alzheimer's overture guidelines

scientific article published in 2022

Impaired PLP-dependent metabolism in brain samples from Huntington disease patients and transgenic R6/1 mice

scientific article published on 14 December 2015

Inactivation of the peroxisomal ABCD2 transporter in the mouse leads to late-onset ataxia involving mitochondria, Golgi and endoplasmic reticulum damage

scientific article

Increased 5-Methylcytosine and Decreased 5-Hydroxymethylcytosine Levels are Associated with Reduced Striatal A2AR Levels in Huntington’s Disease ⬇️

scientific article published on February 6, 2013

Increased C-X-C Motif Chemokine Ligand 12 Levels in Cerebrospinal Fluid as a Candidate Biomarker in Sporadic Amyotrophic Lateral Sclerosis

scientific article published on 17 November 2020

Increased SP4 and SP1 transcription factor expression in the postmortem hippocampus of chronic schizophrenia

scientific article published on 19 August 2014

Increased expression of water channel aquaporin 1 and aquaporin 4 in Creutzfeldt-Jakob disease and in bovine spongiform encephalopathy-infected bovine-PrP transgenic mice

scientific article published on 27 July 2006

Increased oxidation of certain glycolysis and energy metabolism enzymes in the frontal cortex in Lewy body diseases

scientific article

Increased oxidation, glycoxidation, and lipoxidation of brain proteins in prion disease

scientific article published on 23 July 2008

Increased striatal adenosine A2A receptor levels is an early event in Parkinson's disease-related pathology and it is potentially regulated by miR-34b.

scientific article

Individual and regional variations of phospho-tau species in progressive supranuclear palsy

scientific article published on 23 June 2005

Induction of C/EBP beta and GADD153 expression by dopamine in human neuroblastoma cells. Relationship with alpha-synuclein increase and cell damage.

scientific article published on February 2005

Inflammation in Lafora Disease: Evolution with Disease Progression in Laforin and Malin Knock-out Mouse Models

scientific article published on 4 April 2016

Inter-laboratory assessment of PrPSc typing in creutzfeldt-jakob disease: a Western blot study within the NeuroPrion Consortium

scientific article published on 2 July 2008

Inter-laboratory comparison of neuropathological assessments of β-amyloid protein: a study of the BrainNet Europe consortium

scientific article published on 15 March 2008

Interplay between TDP-43 and docosahexaenoic acid-related processes in amyotrophic lateral sclerosis

scientific article published on 12 January 2016

Intranigral dopamine toxicity and alpha-synuclein response in rats

scientific article published on 28 June 2006

Involvement of PrP(C) in kainate-induced excitotoxicity in several mouse strains

scientific article

Involvement of the cerebral cortex in Parkinson disease linked with G2019S LRRK2 mutation without cognitive impairment

scientific article published on 16 March 2010

Isolated cerebral vasculitis associated with rheumatoid arthritis.

scientific article published on 15 May 2010

It may be possible to delay the onset of neurodegenerative diseases with an immunosuppressive drug (rapamycin)

scientific article published on 14 May 2013

Ki-67 proliferative index predicts clinical outcome in patients with atypical or anaplastic meningioma

scientific article

LRRK2 and neurodegeneration

scientific article published on 14 January 2009

Limited Unfolded Protein Response and Inflammation in Neuroserpinopathy

scientific article published on 4 January 2016

Lipid alterations in human frontal cortex in ALS-FTLD-TDP43 proteinopathy spectrum are partly related to peroxisome impairment

scientific article published on 17 December 2020

Lipid alterations in lipid rafts from Alzheimer's disease human brain cortex

scientific article published in January 2010

Lipid raft ER signalosome malfunctions in menopause and Alzheimer's disease

scientific article

Lipidomics of human brain aging and Alzheimer's disease pathology.

scientific article published on 19 June 2015

Lithium treatment decreases activities of tau kinases in a murine model of senescence.

scientific article published in June 2008

Locus coeruleus connectivity alterations in late-life major depressive disorder during a visual oddball task

scientific article published on 27 October 2020

Long non-coding antisense RNA controls Uchl1 translation through an embedded SINEB2 repeat.

scientific article

Loss of SIRT2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance

scientific article published on 5 October 2017

Low molecular weight species of tau in Alzheimer's disease are dependent on tau phosphorylation sites but not on delayed post-mortem delay in tissue processing

scientific article published on 20 February 2006

MPP+ increases alpha-synuclein expression and ERK/MAP-kinase phosphorylation in human neuroblastoma SH-SY5Y cells

scientific article

Maillard reaction versus other nonenzymatic modifications in neurodegenerative processes

scientific article published on 13 December 2007

Memory Improvement in the AβPP/PS1 Mouse Model of Familial Alzheimer’s Disease Induced by Carbamylated-Erythropoietin is Accompanied by Modulation of Synaptic Genes

scientific article published in January 2015

Metabolomics of human brain aging and age-related neurodegenerative diseases

scientific article

MicroRNA Alterations in the Brain and Body Fluids of Humans and Animal Prion Disease Models: Current Status and Perspectives

scientific article published on 23 July 2018

MicroRNA profiling of Parkinson's disease brains identifies early downregulation of miR-34b/c which modulate mitochondrial function

scientific article published on 10 May 2011

Microspectroscopy (μFTIR) reveals co-localization of lipid oxidation and amyloid plaques in human Alzheimer disease brains.

scientific article published on 4 December 2014

Mitochondrial dysfunction and oxidative and endoplasmic reticulum stress in argyrophilic grain disease

scientific article published in April 2011

Mitochondrial dysfunction and oxidative damage cooperatively fuel axonal degeneration in X-linked adrenoleukodystrophy.

scientific article published on 24 September 2013

Mitochondrial dysfunction in central nervous system white matter disorders

scientific article published on 28 May 2014

Modification of brain lipids but not phenotype in alpha-synucleinopathy transgenic mice by long-term dietary n-3 fatty acids

scientific article published on 12 November 2009

Molecular Alterations in the Cerebellum of Sporadic Creutzfeldt-Jakob Disease Subtypes with DJ-1 as a Key Regulator of Oxidative Stress

scientific article published on 14 December 2016

Molecular mechanisms of MLC1 and GLIALCAM mutations in megalencephalic leukoencephalopathy with subcortical cysts

scientific article published on 30 May 2011

Molecular pathology of myofibrillar myopathies.

scientific article published on 03 September 2008

Motor neuron preservation and decrease of in vivo TDP-43 phosphorylation by protein CK-1δ kinase inhibitor treatment

scientific article published on 10 March 2020

Muscle Fiber Atrophy and Regeneration Coexist in Collagen VI-Deficient Human Muscle: Role of Calpain-3 and Nuclear Factor-κB Signaling

scientific article published on 01 October 2012

Mutation loads in different tissues from six pathogenic mtDNA point mutations.

scientific article published on 10 March 2015

Mutations in TIMM50 cause severe mitochondrial dysfunction by targeting key aspects of mitochondrial physiology

scientific article published on 17 May 2019

Myoglobinopathy is an adult-onset autosomal dominant myopathy with characteristic sarcoplasmic inclusions

scientific article published on 27 March 2019

Neuroinflammation in the dorsolateral prefrontal cortex in elderly chronic schizophrenia

scientific article published on 07 January 2019

Neuroinflammatory Gene Regulation, Mitochondrial Function, Oxidative Stress, and Brain Lipid Modifications With Disease Progression in Tau P301S Transgenic Mice as a Model of Frontotemporal Lobar Degeneration-Tau

scientific article published on 10 September 2015

Neuroinflammatory signals in Alzheimer disease and APP/PS1 transgenic mice: correlations with plaques, tangles, and oligomeric species

scientific article published in April 2015

Neuronal death is enhanced and begins during foetal development in type I spinal muscular atrophy spinal cord

scientific article

Neuronal pentraxin 1 contributes to the neuronal damage evoked by amyloid-beta and is overexpressed in dystrophic neurites in Alzheimer's brain.

scientific article

Neuropathology and pathogenesis of encephalitis following amyloid-beta immunization in Alzheimer's disease

scientific article published in January 2004

Neuropathology of Parkinson's disease with the R1441G mutation in LRRK2.

scientific article published in October 2009

Neuropathology of sporadic Parkinson disease before the appearance of parkinsonism: preclinical Parkinson disease ⬇️

scientific article published on September 23, 2010

Neuroprotective role of trans-resveratrol in a murine model of familial Alzheimer's disease

scientific article published in January 2014

New mitochondrial DNA mutations in tRNA associated with three severe encephalopamyopathic phenotypes: neonatal, infantile, and childhood onset ⬇️

scientific article published on May 26, 2012

Nuclear localization and phosphorylation modulate pathological effects of Alpha-Synuclein

scientific article published on 01 January 2019

Nuclear phosphorylated Y142 β-catenin accumulates in astrocytomas and glioblastomas and regulates cell invasion

scientific article published on November 2015

Oxidative Stress in Desminopathies and Myotilinopathies: A Link between Oxidative Damage and Abnormal Protein Aggregation

scientific article published on 04 September 2007

Oxidative and endoplasmic reticulum stress interplay in sporadic amyotrophic lateral sclerosis

scientific article published on 23 August 2007

Oxidative damage compromises energy metabolism in the axonal degeneration mouse model of X-adrenoleukodystrophy

scientific article

Oxidative stress modulates mitochondrial failure and cyclophilin D function in X-linked adrenoleukodystrophy

scientific article

Oxidative stress regulates the ubiquitin-proteasome system and immunoproteasome functioning in a mouse model of X-adrenoleukodystrophy.

scientific article published in March 2013

Oxidative stress underlying axonal degeneration in adrenoleukodystrophy: a paradigm for multifactorial neurodegenerative diseases?

scientific article published on 12 February 2012

Oxidative stress, mitochondrial and proteostasis malfunction in adrenoleukodystrophy: A paradigm for axonal degeneration

scientific article

PINK1-linked parkinsonism is associated with Lewy body pathology

scientific article published on 30 March 2010

PM20D1 is a quantitative trait locus associated with Alzheimer’s disease

scientific article published on 07 May 2018

PPARγ agonist-loaded PLGA-PEG nanocarriers as a potential treatment for Alzheimer's disease: in vitro and in vivo studies

scientific article published on 20 September 2018

PURINE-RELATED METABOLITES AND THEIR CONVERTING ENZYMES ARE ALTERED IN FRONTAL, PARIETAL, AND TEMPORAL CORTEX AT EARLY STAGES OF ALZHEIMER'S DISEASE PATHOLOGY.

scientific article

Phenotypic patterns of desminopathy associated with three novel mutations in the desmin gene.

scientific article published on 05 April 2007

Phenotypic variability within the inclusion body spectrum of basophilic inclusion body disease and neuronal intermediate filament inclusion disease in frontotemporal lobar degenerations with FUS-positive inclusions

scientific article published on 01 September 2012

Phosphorylated tau in neuritic plaques of APP(sw)/Tau (vlw) transgenic mice and Alzheimer disease

scientific article

Pioglitazone halts axonal degeneration in a mouse model of X-linked adrenoleukodystrophy

scientific article

Plasma YKL-40 in the spectrum of neurodegenerative dementia

scientific article published on 12 July 2019

Plasma phosphorylated TDP-43 levels are elevated in patients with frontotemporal dementia carrying a C9orf72 repeat expansion or a GRN mutation

scientific article published on 4 December 2013

Poly(propylene imine) dendrimers with histidine-maltose shell as novel type of nanoparticles for synapse and memory protection

scientific article from 2019

Potential of Microfluidics and Lab-on-Chip Platforms to Improve Understanding of "prion-like" Protein Assembly and Behavior

scientific article published on 08 September 2020

PrP mRNA and protein expression in brain and PrP(c) in CSF in Creutzfeldt-Jakob disease MM1 and VV2.

scientific article published on 18 September 2013

PrP(C) regulates epidermal growth factor receptor function and cell shape dynamics in Neuro2a cells.

scientific article published on 28 May 2013

Presynaptic parkinsonism in multiple system atrophy mimicking Parkinson's disease: a clinicopathological case study

scientific article published in July 2002

Prion Protein Interactome: Identifying Novel Targets in Slowly and Rapidly Progressive Forms of Alzheimer's Disease.

scientific article

Pro-NGF from Alzheimer's disease and normal human brain displays distinctive abilities to induce processing and nuclear translocation of intracellular domain of p75NTR and apoptosis

scientific article

Pro-NGF isolated from the human brain affected by Alzheimer's disease induces neuronal apoptosis mediated by p75NTR.

scientific article

Prognostic implication of clinical, radiologic, and pathologic features in patients with anaplastic gliomas.

scientific article published in February 2003

Progressive supranuclear palsy and corticobasal degeneration: lumping versus splitting

scientific article published in August 2005

Promoter hypermethylation of the phosphatase DUSP22 mediates PKA-dependent TAU phosphorylation and CREB activation in Alzheimer's disease

scientific article

Protein oxidation in Huntington disease affects energy production and vitamin B6 metabolism

scientific article published on August 2010

Protein targets of oxidative damage in human neurodegenerative diseases with abnormal protein aggregates

scientific article published on 06 August 2009

Proteins in human brain cortex are modified by oxidation, glycoxidation, and lipoxidation. Effects of Alzheimer disease and identification of lipoxidation targets.

scientific article published on 29 March 2005

Proteomic and oxidative stress analysis in human brain samples of Huntington disease.

scientific article

Purine metabolism gene deregulation in Parkinson's disease

scientific article published on 18 January 2015

RETRACTED ARTICLE: In situ structural characterization of early amyloid aggregates in Alzheimer’s disease transgenic mice and Octodon degus

retracted scholarly article

RNA editing alterations define manifestation of prion diseases

scientific article published on 06 September 2019

Redox lipidomics to better understand brain aging and function

scientific article published on 18 March 2019

Reduced expression of NO-sensitive guanylyl cyclase in reactive astrocytes of Alzheimer disease, Creutzfeldt-Jakob disease, and multiple sclerosis brains.

scientific article published on December 2004

Reduced striatal adenosine A2A receptor levels define a molecular subgroup in schizophrenia.

scientific article published on 7 January 2014

Reduced striatal ecto-nucleotidase activity in schizophrenia patients supports the "adenosine hypothesis".

scientific article published on 16 June 2013

Reelin Expression in Creutzfeldt-Jakob Disease and Experimental Models of Transmissible Spongiform Encephalopathies.

scientific article published on 10 October 2016

Region-specific vulnerability to lipid peroxidation and evidence of neuronal mechanisms for polyunsaturated fatty acid biosynthesis in the healthy adult human central nervous system.

scientific article published on 6 February 2017

Regional and subtype-dependent miRNA signatures in sporadic Creutzfeldt-Jakob disease are accompanied by alterations in miRNA silencing machinery and biogenesis.

scientific article published on 22 January 2018

Regulation of human cerebrospinal fluid malate dehydrogenase 1 in sporadic Creutzfeldt-Jakob disease patients

scientific article

Relevance of host tau in tau seeding and spreading in tauopathies

scientific article published on 27 August 2019

Retraction Note: In situ structural characterization of early amyloid aggregates in Alzheimer's disease transgenic mice and Octodon degus

scientific article published on 10 November 2020

Revealing Adenosine A2A-Dopamine D2 Receptor Heteromers in Parkinson's Disease Post-Mortem Brain through a New AlphaScreen-Based Assay

scientific article published on 23 July 2019

Risk of transmission of systemic transthyretin amyloidosis after domino liver transplantation

scientific article published in December 2010

Role of cellular prion protein in interneuronal amyloid transmission

scientific article published on 9 March 2018

SFPQ and Tau: critical factors contributing to rapid progression of Alzheimer's disease

scientific article published on 23 June 2020

Severe Alterations in Lipid Composition of Frontal Cortex Lipid Rafts from Parkinson’s Disease and Incidental Parkinson’s Disease ⬇️

scientific article published on June 22, 2011

Severe cerebral white matter involvement in a case of dentatorubropallidoluysian atrophy studied at autopsy

scientific article published on 01 June 2004

Sixty years old is the breakpoint of human frontal cortex aging

scientific article published on 12 December 2016

Smelling the Dark Proteome: Functional Characterization of PITH Domain-Containing Protein 1 (C1orf128) in Olfactory Metabolism

scientific article published on 13 November 2020

Specific Metabolomics Adaptations Define a Differential Regional Vulnerability in the Adult Human Cerebral Cortex

scientific article published on 08 December 2016

Specific small-RNA signatures in the amygdala at premotor and motor stages of Parkinson's disease revealed by deep sequencing analysis.

scientific article published on 2 November 2015

Spontaneous generation of infectious prion disease in transgenic mice

scientific article published on December 2013

Sporadic Creutzfeldt-Jakob disease with glial PrPRes nuclear and perinuclear immunoreactivity

scientific article published on 19 August 2018

Sporadic MM2-thalamic + cortical Creutzfeldt-Jakob disease: Utility of diffusion tensor imaging in the detection of cortical involvement in vivo.

scientific article published on 6 November 2015

Staging of neurofibrillary pathology in Alzheimer's disease: a study of the BrainNet Europe Consortium

scientific article published on 26 March 2008

Stereotaxic administration of 1-methyl-4-phenylpyridinium ion (MPP+) decreases striatal fructose 2,6-bisphosphate in rats

scientific article published in May 1994

Strain-Specific Altered Regulatory Response of Rab7a and Tau in Creutzfeldt-Jakob Disease and Alzheimer's Disease

scientific article published on 14 January 2016

Stress response in the central nervous system of a transgenic mouse model of bovine spongiform encephalopathy

scientific article published on 09 August 2007

Striatal adenosine A2A receptor expression is controlled by S-adenosyl-L-methionine-mediated methylation

scientific article

Subtype and regional regulation of prion biomarkers in sporadic Creutzfeldt-Jakob disease

scientific article published on 30 April 2015

Subtype and regional-specific neuroinflammation in sporadic creutzfeldt-jakob disease

scientific article

Succination of Protein Thiols in Human Brain Aging

scientific article published on 06 March 2020

TAR DNA-Binding protein 43 accumulation in protein aggregate myopathies

scientific article published in March 2009

TGF-beta1 increases tyrosine hydroxylase expression by a mechanism blocked by BMP-2 in human neuroblastoma SH-SY5Y cells

scientific article published on December 2002

Target genes of neuron-restrictive silencer factor are abnormally up-regulated in human myotilinopathy

scientific article

Tau hyperphosphorylation induces oligomeric insulin accumulation and insulin resistance in neurons.

scientific article

Tau-positive nuclear indentations in P301S tauopathy mice.

scientific article published on 24 June 2016

Tauroursodeoxycholic bile acid arrests axonal degeneration by inhibiting the unfolded protein response in X-linked adrenoleukodystrophy

scientific article published on 21 December 2016

The Presence of Human Herpesvirus 6 in the Brain in Health and Disease

scientific article published on 06 November 2020

The Quest for Cellular Prion Protein Functions in the Aged and Neurodegenerating Brain

scientific article published on 02 March 2020

The Structure of the Spinal Cord Ependymal Region in Adult Humans Is a Distinctive Trait among Mammals

scientific article published in 2021

The glial phosphorylase of glycogen isoform is reduced in the dorsolateral prefrontal cortex in chronic schizophrenia

scientific article published on 4 May 2016

The human brainome: network analysis identifies HSPA2 as a novel Alzheimer’s disease target

The loss of c-Jun N-terminal protein kinase activity prevents the amyloidogenic cleavage of amyloid precursor protein and the formation of amyloid plaques in vivo.

scientific article published in November 2011

The serine protease inhibitor neuroserpin is required for normal synaptic plasticity and regulates learning and social behavior

scientific article published on 15 November 2017

Transcriptional network analysis in frontal cortex in Lewy body diseases with focus on dementia with Lewy bodies

scientific article published on 21 March 2017

Transcriptomic profiling of TK2 deficient human skeletal muscle suggests a role for the p53 signalling pathway and identifies growth and differentiation factor-15 as a potential novel biomarker for mitochondrial myopathies

scientific article published on February 2014

Transgenic mice overexpressing the full-length neurotrophin receptor TrkC exhibit increased catecholaminergic neuron density in specific brain areas and increased anxiety-like behavior and panic reaction

scientific article published on 11 September 2006

Tubers from patients with tuberous sclerosis complex are characterized by changes in microtubule biology through ROCK2 signalling.

scientific article published on 29 April 2014

Type-1 cannabinoid receptor activity during Alzheimer's disease progression.

scientific article published in January 2014

Type-dependent oxidative damage in frontotemporal lobar degeneration: cortical astrocytes are targets of oxidative damage

scientific article published in December 2008

Unexpected expression of alpha- and beta-globin in mesencephalic dopaminergic neurons and glial cells

scientific article

Unveiling the olfactory proteostatic disarrangement in Parkinson's disease by proteome-wide profiling

scientific article published on 25 September 2018

Up-regulation of the Kv3.4 potassium channel subunit in early stages of Alzheimer's disease.

scientific article

Upregulation of a small vault RNA (svtRNA2-1a) is an early event in Parkinson disease and induces neuronal dysfunction.

scientific article published on May 2013

VDAC and ERalpha interaction in caveolae from human cortex is altered in Alzheimer's disease.

scientific article published on 10 July 2009

Variably protease-sensitive prionopathy presenting within ALS/FTD spectrum

scientific article published on 21 September 2018

Whole genome grey and white matter DNA methylation profiles in dorsolateral prefrontal cortex.

scientific article published on 20 January 2017

YKL40 in sporadic amyotrophic lateral sclerosis: cerebrospinal fluid levels as a prognosis marker of disease progression

scientific article published on 01 September 2018

α-Synuclein accumulates in huntingtin inclusions but forms independent filaments and its deficiency attenuates early phenotype in a mouse model of Huntington's disease.

scientific article

αB-crystallin and HSP27 in glial cells in tauopathies

scientific article published on 2 July 2014

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