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List of works by Oscar Della Pasqua

Adaptive trials in paediatric development: dealing with heterogeneity and uncertainty in pharmacokinetic differences in children ⬇️

scientific article published on August 1, 2012

Analysis of responses in migraine modelling using hidden Markov models

scientific article

Assessing the Probability of Drug-Induced QTc-Interval Prolongation During Clinical Drug Development

scientific article published on November 2, 2011

Can phenotypic data complement our understanding of antimycobacterial effects for drug combinations?

scientific article published on 01 December 2019

Correction to: Effect of Age-Related Factors on the Pharmacokinetics of Lamotrigine and Potential Implications for Maintenance Dose Optimisation in Future Clinical Trials

scientific article published on 01 August 2018

Development of Paediatric Medicines: Concepts and Principles ⬇️

scientific article published on January 1, 2011

Do pharmacokinetic polymorphisms explain treatment failure in high-risk patients with neuroblastoma? ⬇️

scientific article published on 02 February 2011

Double-blind, randomized, placebo-controlled study of trofinetide in pediatric Rett syndrome

scientific article published on 27 March 2019

Drug repurposing in neurological diseases: an integrated approach to reduce trial and error

scientific article published on 06 June 2019

Effect of Age-Related Factors on the Pharmacokinetics of Lamotrigine and Potential Implications for Dose Optimisation in Epilepsy Patients.

scientific article

Evaluation of pharmacokinetic-pharmacodynamic relationships and selection of drug combinations for tuberculosis

scientific article published on 15 May 2020

Feasibility of a Fixed-Dose Regimen of Pyrazinamide and Its Impact on Systemic Drug Exposure and Liver Safety in Patients with Tuberculosis ⬇️

scientific article published on July 9, 2012

Impact of disease progression on individual IPSS trajectories and consequences of immediate versus delayed start of treatment in patients with moderate or severe LUTS associated with BPH

scientific article published on 11 May 2019

Lack of compliance of European Public Assessment Reports to guidelines for paediatric drug development before the introduction of paediatric investigation plans ⬇️

scientific article published on January 18, 2013

Mimicking in-vivo exposures to drug combinations in-vitro: anti-tuberculosis drugs in lung lesions and the hollow fiber model of infection

scientific article published on 13 September 2019

Model antibiotic use to improve outcomes

scientific article published on 19 October 2020

Model-based meta-analysis of individual IPSS trajectories in patients with benign prostatic hyperplasia with moderate or severe symptoms

scientific article published on 06 March 2020

Model-based meta-analysis of the time to first acute urinary retention or BPH-related surgery in patients with moderate or severe symptoms

scientific article published on 28 November 2020

Modelling of the outcome of non-inferiority trials by integration of historical data ⬇️

scientific article published on August 21, 2011

Optimised protocol design for the screening of analgesic compounds in neuropathic pain ⬇️

scientific article published on November 30, 2012

Pharmacokinetic interactions and dosing rationale for antiepileptic drugs in adults and children.

scientific article

Population pharmacokinetics of abacavir in infants, toddlers and children ⬇️

scientific article published on June 1, 2013

Scaling of pharmacokinetics across paediatric populations: the lack of interpolative power of allometric models ⬇️

scientific article published on September 1, 2012

Translation of drug effects from experimental models of neuropathic pain and analgesia to humans ⬇️

scientific article published on 03 March 2012

Use of prior knowledge and extrapolation in paediatric drug development: A case study with deferasirox

article

What is the right dose for children? ⬇️

scientific article published on October 1, 2010

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