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List of works by Prem P Chapagain

A Conserved Tryptophan in the Ebola Virus Matrix Protein C-Terminal Domain Is Required for Efficient Virus-Like Particle Formation

scientific article published on 22 May 2020

A cationic, C-terminal patch and structural rearrangements in Ebola virus matrix VP40 protein control its interactions with phosphatidylserine.

scientific article published on 18 January 2018

A cylindrical assembly model and dynamics of the Ebola virus VP40 structural matrix.

scientific article

A dominant variant in the PDE1C gene is associated with nonsyndromic hearing loss

scientific article published on 02 June 2018

Amino acid 118 in the Deafness Causing (DFNA20/26) ACTG1 gene is a Mutational Hot Spot

scientific article published on 28 April 2018

Building climate change resilience by using a versatile toolkit for local governments and communities in rural Himalaya

scientific article published on 12 May 2020

Ca2+ and Mg2+ modulate conformational dynamics and stability of downstream regulatory element antagonist modulator.

scientific article published on 10 March 2015

Characterization of ATPase Activity of P2RX2 Cation Channel

scientific article

Characterization of molecular interactions between Escherichia coli RNA polymerase and topoisomerase I by molecular simulations

scientific article published on 22 July 2016

Computational simulations of protein folding to engineer amino acid sequences to encourage desired supersecondary structure formation

scientific article published in January 2013

Conformational Flexibility of the Protein-Protein Interfaces of the Ebola Virus VP40 Structural Matrix Filament

scientific article published on 16 October 2019

Cooperative structural transitions in amyloid-like aggregation

scientific article

Covalent Complex of DNA and Bacterial Topoisomerase: Implications in Antibacterial Drug Development

scientific article published on 18 March 2020

DNA supercoiling, a critical signal regulating the basal expression of the lac operon in Escherichia coli

scientific article

Detection of lipid-induced structural changes of the Marburg virus matrix protein VP40 using hydrogen/deuterium exchange-mass spectrometry

scientific article

Differentiating Parallel and Antiparallel DNA Duplexes in the Gas Phase Using Trapped Ion Mobility Spectrometry

scientific article published on 27 June 2018

Direct observation of a 91 bp LacI-mediated, negatively supercoiled DNA loop by atomic force microscope

scientific article published on 15 February 2016

Discovery of novel bacterial topoisomerase I inhibitors by use of in silico docking and in vitro assays.

scientific article

EF-hands in Neuronal Calcium Sensor Downstream Regulatory Element Antagonist Modulator Demonstrate Submillimolar Affinity for Li+: a new prospect for Li+ therapy

scientific article published on 11 August 2020

ELMOD3, a novel causative gene, associated with human autosomal dominant nonsyndromic and progressive hearing loss

scientific article published on 30 April 2018

Excluded volume entropic effects on protein unfolding times and intermediary stability

scientific article

Exploring Structural and Optical Properties of Fluorescent Proteins by Squeezing: Modeling High-Pressure Effects on the mStrawberry and mCherry Red Fluorescent Proteins ⬇️

scientific article published on October 5, 2012

Exploring the diffusion of molecular oxygen in the red fluorescent protein mCherry using explicit oxygen molecular dynamics simulations

scientific article published on 14 February 2013

Fluorescence from Multiple Chromophore Hydrogen-Bonding States in the Far-Red Protein TagRFP675.

scientific article published on 22 July 2016

Fluorescent protein barrel fluctuations and oxygen diffusion pathways in mCherry

scientific article published on December 2011

Free-energy landscapes and thermodynamic parameters of complex molecules from nonequilibrium simulation trajectories

scientific article published on 7 June 2011

Genetic basis of hearing loss in Spanish, Hispanic and Latino populations.

scientific article published on 10 January 2018

Graphene-VP40 interactions and potential disruption of the Ebola virus matrix filaments.

scientific article published on 13 September 2017

Hydrogen bond flexibility correlates with Stokes shift in mPlum variants

scientific article

Identification of HMGA2 inhibitors by AlphaScreen-based ultra-high-throughput screening assays

scientific article published on 02 November 2020

In Silico Investigations of Calcium Phosphate Mineralization in Extracellular Vesicles

scientific article published on 22 March 2018

In-silico identification of the vaccine candidate epitopes against the Lassa virus hemorrhagic fever

scientific article published on 06 May 2020

Indispensable Role of Ion Channels and Transporters in the Auditory System.

scientific article

Interdomain salt-bridges in the Ebola virus protein VP40 and their role in domain association and plasma membrane localization

scientific article

Intricate Functions of Matrix Metalloproteinases in Physiological and Pathological Conditions.

scientific article published on 17 May 2016

Investigating molecular interactions between oxidized neuroglobin and cytochrome c.

scientific article published on 12 July 2018

Kinetics of peptide secondary structure conversion during amyloid β-protein fibrillogenesis.

scientific article published in May 2012

Lattice model simulation of interchain protein interactions and the folding dynamics and dimerization of the GCN4 Leucine zipper.

scientific article

Lattice model simulations of the effects of the position of a peptide trigger segment on helix folding and dimerization

scientific article

Lipid II Binding and Transmembrane Properties of Various Antimicrobial Lanthipeptides

scientific article published on 07 December 2021

Measles and Nipah virus assembly: Specific lipid binding drives matrix polymerization

scientific article published on 20 July 2022

Membrane association and localization dynamics of the Ebola virus matrix protein VP40.

scientific article published on 12 July 2017

Membrane pore formation and ion selectivity of the Ebola virus delta peptide

scientific article published on 01 March 2019

Microfluidics-based selection of red-fluorescent proteins with decreased rates of photobleaching

scientific article

Molecular Dynamics Simulations of Conformational Conversions in Transformer Proteins

scientific article published on 01 January 2019

Molecular Structure and Regulation of P2X Receptors With a Special Emphasis on the Role of P2X2 in the Auditory System.

scientific article

Molecular dynamics investigations of the α-helix to β-barrel conformational transformation in the RfaH transcription factor

scientific article

Molecular mechanisms of pore formation and membrane disruption by the antimicrobial lantibiotic peptide Mutacin 1140

scientific article published on 31 May 2019

Mutation of Hydrophobic Residues in the C-Terminal Domain of the Marburg Virus Matrix Protein VP40 Disrupts Trafficking to the Plasma Membrane

scientific article published on 24 April 2020

Pairwise amino acid secondary structural propensities

scientific article published on 15 April 2015

Plasma membrane association facilitates conformational changes in the Marburg virus protein VP40 dimer.

scientific article published on April 2017

Potential RNA-dependent RNA polymerase inhibitors as prospective therapeutics against SARS-CoV-2

scientific article published on 29 May 2020

Removal of kinetic traps and enhanced protein folding by strategic substitution of amino acids in a model alpha-helical hairpin peptide

scientific article published in February 2006

Sampling of states for estimating the folding funnel entropy and energy landscape of a model alpha-helical hairpin peptide

scientific article published in August 2007

Self-organization in protein folding and the hydrophobic interaction

scientific article published in August 2005

Self-organizing dynamics in protein folding

scientific article published on January 2008

Single-stranded DNA structural diversity: TAGGGT from monomers to dimers to tetramer formation

scientific article published on 18 February 2019

Stabilization of native and non-native structures by salt bridges in a lattice model of the GCN4 leucine dimer.

scientific article published in January 2010

Structural propensities and entropy effects in peptide helix-coil transitions

scientific article published on 17 September 2012

Structures of the kinetically trapped i-motif DNA intermediates.

scientific article published on September 2016

The Ebola virus protein VP40 hexamer enhances the clustering of PI(4,5)P2 lipids in the plasma membrane.

scientific article

The Integrin Binding Peptide, ATN-161, as a Novel Therapy for SARS-CoV-2 Infection

scientific article published on 16 October 2020

The Role of the Interdomain Interactions on RfaH Dynamics and Conformational Transformation

scientific article

The trigger sequence in the GCN4 leucine zipper: alpha-helical propensity and multistate dynamics of folding and dimerization

scientific article published in November 2008

Zika Virus: An Emerging Global Health Threat

scientific article published on 8 December 2017

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