List of works - Grace K. Pavlath

A combinatorial role for NFAT5 in both myoblast migration and differentiation during skeletal muscle myogenesis

scientific article published on 12 December 2006

A gene-trap strategy identifies quiescence-induced genes in synchronized myoblasts

scientific article

A muscle stem cell for every muscle: variability of satellite cell biology among different muscle groups

scientific article

A new function for odorant receptors: MOR23 is necessary for normal tissue repair in skeletal muscle

scientific article

A senescence accelerated mouse model to study aging in the larynx.

scientific article published in June 2010

A tale of two niches: differential functions for VCAM-1 in satellite cells under basal and injured conditions

scientific article

Activation and cellular localization of the cyclosporine A-sensitive transcription factor NF-AT in skeletal muscle cells

scientific article

Ageing and muscular dystrophy differentially affect murine pharyngeal muscles in a region-dependent manner

scientific article published on 17 October 2014

Altered primary myogenesis in NFATC3(-/-) mice leads to decreased muscle size in the adult

scientific journal article

An Antibody to Detect Alanine-Expanded PABPN1: A New Tool to Study Oculopharyngeal Muscular Dystrophy

scientific article published on October 2015

Biochemical Isolation of Myonuclei from Mouse Skeletal Muscle Tissue.

scientific article published in December 2017

Biochemical isolation of myonuclei employed to define changes to the myonuclear proteome that occur with aging

scientific article published on 23 May 2017

CD44 regulates myoblast migration and differentiation

scientific article published on 01 November 2006

Calcineurin activity is required for the initiation of skeletal muscle differentiation

scientific article

Calcineurin differentially regulates maintenance and growth of phenotypically distinct muscles

scientific article

Calcineurin initiates skeletal muscle differentiation by activating MEF2 and MyoD.

scientific article

Cell fusion in skeletal muscle--central role of NFATC2 in regulating muscle cell size

scientific article

Cell-type-dependent up-regulation of in vitro mineralization after overexpression of the osteoblast-specific transcription factor Runx2/Cbfal

scientific article published on November 2002

Chemokine expression and control of muscle cell migration during myogenesis ⬇️

scientific article published on August 24, 2010

Control of mRNA stability contributes to low levels of nuclear poly(A) binding protein 1 (PABPN1) in skeletal muscle

scientific article published on October 2013

Corrigendum to “Sca-1 negatively regulates proliferation and differentiation of muscle cells” [Dev. Biol. 283 (2005) 240–252]

scholarly article published in Developmental Biology

Creatine kinase B is necessary to limit myoblast fusion during myogenesis

scientific article published on 25 March 2015

Decrease of myofiber branching via muscle-specific expression of the olfactory receptor mOR23 in dystrophic muscle leads to protection against mechanical stress

scientific article

Defective myoblasts identified in Duchenne muscular dystrophy

scientific article

Differentially activated macrophages orchestrate myogenic precursor cell fate during human skeletal muscle regeneration

scientific article published in February 2013

Distinct roles for classical nuclear import receptors in the growth of multinucleated muscle cells

scientific article

Forming a multinucleated cell: molecules that regulate myoblast fusion

scientific article published on January 2004

Hepatocyte growth factor affects satellite cell activation and differentiation in regenerating skeletal muscle

scientific article published on 01 January 2000

Human myoblasts and muscle-derived SP cells

article by Grace K Pavlath et al published 2005 in Methods in Molecular Medicine

IL-4 acts as a myoblast recruitment factor during mammalian muscle growth

scientific journal article

Incidence and severity of myofiber branching with regeneration and aging

scientific article

Inhibition of myoblast migration by prostacyclin is associated with enhanced cell fusion

scientific article published on 08 May 2007

Karyopherin Alpha 1 Regulates Satellite Cell Proliferation and Survival by Modulating Nuclear Import

scientific article published on 19 July 2016

Last Word on Point:Counterpoint: Satellite cell addition is/is not obligatory for skeletal muscle hypertrophy

scientific article published on 01 September 2007

Localization of muscle gene products in nuclear domains

scientific article

Loss of nuclear poly(A)-binding protein 1 causes defects in myogenesis and mRNA biogenesis.

scientific article

MLL5, a trithorax homolog, indirectly regulates H3K4 methylation, represses cyclin A2 expression, and promotes myogenic differentiation

scholarly article

MOR23 promotes muscle regeneration and regulates cell adhesion and migration

scientific article

Mannose receptor regulates myoblast motility and muscle growth

scientific article

Molecular control of mammalian myoblast fusion

scientific article published on January 2008

Molecular mechanisms of myoblast fusion across species

scientific article published on January 2011

Multiple roles of calcineurin in skeletal muscle growth.

scientific article

Myoblast fusion: lessons from flies and mice

scientific article published on February 2012

NFAT: ubiquitous regulator of cell differentiation and adaptation

scientific article

Non-equivalence of nuclear import among nuclei in multinucleated skeletal muscle cells.

scientific article published on 28 December 2017

Normal dystrophin transcripts detected in Duchenne muscular dystrophy patients after myoblast transplantation

scientific article

Novel mouse models of oculopharyngeal muscular dystrophy (OPMD) reveal early onset mitochondrial defects and suggest loss of PABPN1 may contribute to pathology.

scientific article published on 29 May 2017

Nuclear poly(A) binding protein 1 (PABPN1) and Matrin3 interact in muscle cells and regulate RNA processing

scientific article published on 7 September 2017

PABPN1: molecular function and muscle disease

scientific article published on 24 May 2013

Pharyngeal Satellite Cells Undergo Myogenesis Under Basal Conditions and Are Required for Pharyngeal Muscle Maintenance

scientific article

Phosphocreatine as an energy source for actin cytoskeletal rearrangements during myoblast fusion

scientific article published on 17 April 2008

Plasticity of the differentiated state

scientific article

Point:Counterpoint: Satellite cell addition is/is not obligatory for skeletal muscle hypertrophy

scientific article published on 08 February 2007

Post-transcriptional regulation of Pabpn1 by the RNA binding protein HuR

Prostaglandin F2α stimulates growth of skeletal muscle cells via an NFATC2-dependent pathway ⬇️

scientific article published on April 14, 2003

Proteomic analysis reveals that wildtype and alanine-expanded nuclear poly(A)-binding protein exhibit differential interactions in skeletal muscle

scientific article published on 05 March 2019

RNA-binding proteins and gene regulation in myogenesis

scientific article

Regeneration of transgenic skeletal muscles with altered timing of expression of the basic helix-loop-helix muscle regulatory factor MRF4

scientific journal article

Regulation of class I MHC expression in skeletal muscle: deleterious effect of aberrant expression on myogenesis

scientific article published on 01 April 2002

Regulation of the growth of multinucleated muscle cells by an NFATC2-dependent pathway

scientific article

Retroviral vectors applied to gene regulation studies

scientific article published in January 2002

Rhabdomyosarcoma: current challenges and their implications for developing therapies.

scientific article

Runx2/Cbfa1 stimulates transdifferentiation of primary skeletal myoblasts into a mineralizing osteoblastic phenotype.

scientific article published in November 2004

Runx2/Cbfa1-genetically engineered skeletal myoblasts mineralize collagen scaffolds in vitro

scientific article published in November 2004

Sca-1 expression is required for efficient remodeling of the extracellular matrix during skeletal muscle regeneration.

scientific article

Sca-1 influences the innate immune response during skeletal muscle regeneration

scientific article

Sca-1 is negatively regulated by TGF-beta1 in myogenic cells

scientific article

Sca-1 negatively regulates proliferation and differentiation of muscle cells.

scientific article

Skeletal muscle atrophy leads to loss and dysfunction of muscle precursor cells

scientific article published on 25 August 2004

Skeletal muscle is a vital tissue. Preface.

scientific article published in January 2011

Spatial and functional restriction of regulatory molecules during mammalian myoblast fusion

scientific article

Splice variants of the human ZC3H14 gene generate multiple isoforms of a zinc finger polyadenosine RNA binding protein

scientific article

Stretch-induced myoblast proliferation is dependent on the COX2 pathway

scientific article published on 15 September 2005

The COX-2 pathway is essential during early stages of skeletal muscle regeneration

scientific article

The COX-2 pathway regulates growth of atrophied muscle via multiple mechanisms

scientific article published on 8 February 2006

The N-BAR domain protein, Bin3, regulates Rac1- and Cdc42-dependent processes in myogenesis

scientific journal article

The small chromatin-binding protein p8 coordinates the association of anti-proliferative and pro-myogenic proteins at the myogenin promoter

scientific journal article

Use of a Grant Writing Class in Training PhD Students

scientific article published on 6 April 2016

List of works by Grace K. Pavlath

A combinatorial role for NFAT5 in both myoblast migration and differentiation during skeletal muscle myogenesis

A gene-trap strategy identifies quiescence-induced genes in synchronized myoblasts

A muscle stem cell for every muscle: variability of satellite cell biology among different muscle groups

A new function for odorant receptors: MOR23 is necessary for normal tissue repair in skeletal muscle

A senescence accelerated mouse model to study aging in the larynx.

A tale of two niches: differential functions for VCAM-1 in satellite cells under basal and injured conditions

Activation and cellular localization of the cyclosporine A-sensitive transcription factor NF-AT in skeletal muscle cells

Ageing and muscular dystrophy differentially affect murine pharyngeal muscles in a region-dependent manner

Altered primary myogenesis in NFATC3(-/-) mice leads to decreased muscle size in the adult

An Antibody to Detect Alanine-Expanded PABPN1: A New Tool to Study Oculopharyngeal Muscular Dystrophy

Biochemical Isolation of Myonuclei from Mouse Skeletal Muscle Tissue.

Biochemical isolation of myonuclei employed to define changes to the myonuclear proteome that occur with aging

CD44 regulates myoblast migration and differentiation

Calcineurin activity is required for the initiation of skeletal muscle differentiation

Calcineurin differentially regulates maintenance and growth of phenotypically distinct muscles

Calcineurin initiates skeletal muscle differentiation by activating MEF2 and MyoD.

Cell fusion in skeletal muscle--central role of NFATC2 in regulating muscle cell size

Cell-type-dependent up-regulation of in vitro mineralization after overexpression of the osteoblast-specific transcription factor Runx2/Cbfal

Chemokine expression and control of muscle cell migration during myogenesis ⬇️

Control of mRNA stability contributes to low levels of nuclear poly(A) binding protein 1 (PABPN1) in skeletal muscle

Corrigendum to “Sca-1 negatively regulates proliferation and differentiation of muscle cells” [Dev. Biol. 283 (2005) 240–252]

Creatine kinase B is necessary to limit myoblast fusion during myogenesis

Decrease of myofiber branching via muscle-specific expression of the olfactory receptor mOR23 in dystrophic muscle leads to protection against mechanical stress

Defective myoblasts identified in Duchenne muscular dystrophy

Differentially activated macrophages orchestrate myogenic precursor cell fate during human skeletal muscle regeneration

Distinct roles for classical nuclear import receptors in the growth of multinucleated muscle cells

Forming a multinucleated cell: molecules that regulate myoblast fusion

Hepatocyte growth factor affects satellite cell activation and differentiation in regenerating skeletal muscle

Human myoblasts and muscle-derived SP cells

IL-4 acts as a myoblast recruitment factor during mammalian muscle growth

Incidence and severity of myofiber branching with regeneration and aging

Inhibition of myoblast migration by prostacyclin is associated with enhanced cell fusion

Karyopherin Alpha 1 Regulates Satellite Cell Proliferation and Survival by Modulating Nuclear Import

Last Word on Point:Counterpoint: Satellite cell addition is/is not obligatory for skeletal muscle hypertrophy

Localization of muscle gene products in nuclear domains

Loss of nuclear poly(A)-binding protein 1 causes defects in myogenesis and mRNA biogenesis.

MLL5, a trithorax homolog, indirectly regulates H3K4 methylation, represses cyclin A2 expression, and promotes myogenic differentiation

MOR23 promotes muscle regeneration and regulates cell adhesion and migration

Mannose receptor regulates myoblast motility and muscle growth

Molecular control of mammalian myoblast fusion

Molecular mechanisms of myoblast fusion across species

Multiple roles of calcineurin in skeletal muscle growth.

Myoblast fusion: lessons from flies and mice

NFAT: ubiquitous regulator of cell differentiation and adaptation

Non-equivalence of nuclear import among nuclei in multinucleated skeletal muscle cells.

Normal dystrophin transcripts detected in Duchenne muscular dystrophy patients after myoblast transplantation

Novel mouse models of oculopharyngeal muscular dystrophy (OPMD) reveal early onset mitochondrial defects and suggest loss of PABPN1 may contribute to pathology.

Nuclear poly(A) binding protein 1 (PABPN1) and Matrin3 interact in muscle cells and regulate RNA processing

PABPN1: molecular function and muscle disease

Pharyngeal Satellite Cells Undergo Myogenesis Under Basal Conditions and Are Required for Pharyngeal Muscle Maintenance

Phosphocreatine as an energy source for actin cytoskeletal rearrangements during myoblast fusion

Plasticity of the differentiated state

Point:Counterpoint: Satellite cell addition is/is not obligatory for skeletal muscle hypertrophy

Post-transcriptional regulation of Pabpn1 by the RNA binding protein HuR

Prostaglandin F2α stimulates growth of skeletal muscle cells via an NFATC2-dependent pathway ⬇️

Proteomic analysis reveals that wildtype and alanine-expanded nuclear poly(A)-binding protein exhibit differential interactions in skeletal muscle

RNA-binding proteins and gene regulation in myogenesis

Regeneration of transgenic skeletal muscles with altered timing of expression of the basic helix-loop-helix muscle regulatory factor MRF4

Regulation of class I MHC expression in skeletal muscle: deleterious effect of aberrant expression on myogenesis

Regulation of the growth of multinucleated muscle cells by an NFATC2-dependent pathway

Retroviral vectors applied to gene regulation studies

Rhabdomyosarcoma: current challenges and their implications for developing therapies.

Runx2/Cbfa1 stimulates transdifferentiation of primary skeletal myoblasts into a mineralizing osteoblastic phenotype.

Runx2/Cbfa1-genetically engineered skeletal myoblasts mineralize collagen scaffolds in vitro

Sca-1 expression is required for efficient remodeling of the extracellular matrix during skeletal muscle regeneration.

Sca-1 influences the innate immune response during skeletal muscle regeneration

Sca-1 is negatively regulated by TGF-beta1 in myogenic cells

Sca-1 negatively regulates proliferation and differentiation of muscle cells.

Skeletal muscle atrophy leads to loss and dysfunction of muscle precursor cells

Skeletal muscle is a vital tissue. Preface.

Spatial and functional restriction of regulatory molecules during mammalian myoblast fusion

Splice variants of the human ZC3H14 gene generate multiple isoforms of a zinc finger polyadenosine RNA binding protein

Stretch-induced myoblast proliferation is dependent on the COX2 pathway

The COX-2 pathway is essential during early stages of skeletal muscle regeneration

The COX-2 pathway regulates growth of atrophied muscle via multiple mechanisms

The N-BAR domain protein, Bin3, regulates Rac1- and Cdc42-dependent processes in myogenesis

The small chromatin-binding protein p8 coordinates the association of anti-proliferative and pro-myogenic proteins at the myogenin promoter

Use of a Grant Writing Class in Training PhD Students