List of works by Nelson O Gekara

Biochemical and microscopic analysis of inflammasome complex formation

scientific article published on 10 June 2019

Chromatin-bound cGAS is an inhibitor of DNA repair and hence accelerates genome destabilization and cell death

scientific article published on 23 September 2019

Comet and micronucleus assays for analyzing DNA damage and genome integrity

scientific article published on 18 June 2019

DNA damage primes the type I interferon system via the cytosolic DNA sensor STING to promote anti-microbial innate immunity

scientific article

DNA damage-induced immune response: Micronuclei provide key platform.

scientific article

Detection of a microbial metabolite by STING regulates inflammasome activation in response to Chlamydia trachomatis infection.

scientific article

Deubiquitinase MYSM1 Regulates Innate Immunity through Inactivation of TRAF3 and TRAF6 Complexes

scientific article published on 12 October 2015

Fast type I interferon response protects astrocytes from flavivirus infection and virus-induced cytopathic effects

scientific article (publication date: 24 October 2016)

Hydrogen peroxide release by bacteria suppresses inflammasome-dependent innate immunity

scientific article published on 02 August 2019

Loss of the DNA Damage Repair Kinase ATM Impairs Inflammasome-Dependent Anti-Bacterial Innate Immunity.

scientific article published on 9 July 2016

Loss of the DNA Damage Repair Kinase ATM Impairs Inflammasome-Dependent Anti-Bacterial Innate Immunity.

scientific article

Quantitative proteomics analysis of macrophage-derived lipid rafts reveals induction of autophagy pathway at the early time of Francisella tularensis LVS infection

scientific article published on 7 January 2014

Subversion of innate immune responses by Francisella involves the disruption of TRAF3 and TRAF6 signaling complexes.

scientific article

TUBE and UbiCRest assays for elucidating polyubiquitin modifications in protein complexes

scientific article published on 11 June 2019

The deubiquitinase MYSM1 dampens NOD2-mediated inflammation and tissue damage by inactivating the RIP2 complex

scientific article published in Nature Communications

The innate immune DNA sensor cGAS: A membrane, cytosolic, or nuclear protein?

scientific article published on 14 May 2019

Type I interferon protects mice from fatal neurotropic infection with Langat virus by systemic and local antiviral responses.

scientific article published on 13 August 2014

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