List of works - Philip L Lorenzi

A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily

scientific article published on 26 September 2018

A murine preclinical syngeneic transplantation model for breast cancer precision medicine.

scientific article

Adipose tissue-specific ablation of Ces1d causes metabolic dysregulation in mice

scientific article published on 22 April 2022

Amino acid metabolism in hematologic malignancies and the era of targeted therapy

scientific article published on 15 August 2019

CD38-Mediated Immunosuppression as a Mechanism of Tumor Cell Escape from PD-1/PD-L1 Blockade

scientific article published on 16 July 2018

Enteral Activation of WR-2721 Mediates Radioprotection and Improved Survival from Lethal Fractionated Radiation

scientific article published in Scientific Reports

GPR1 and CMKLR1 control lipid metabolism to support development of clear cell renal cell carcinoma

scientific article published on 19 April 2024

Glutaminase Activity of L-Asparaginase Contributes to Durable Preclinical Activity against Acute Lymphoblastic Leukemia

scientific article published on 17 June 2019

Inhibition of mitochondrial complex I reverses NOTCH1-driven metabolic reprogramming in T-cell acute lymphoblastic leukemia

scientific article published on 19 May 2022

Interfering with lipid metabolism through targeting CES1 sensitizes hepatocellular carcinoma for chemotherapy

scientific article published on 24 January 2023

Mechanism of Catalysis by l-Asparaginase

scientific article published on 04 May 2020

Medium-Chain Acyl-CoA Dehydrogenase Protects Mitochondria from Lipid Peroxidation in Glioblastoma

scientific article published on 26 May 2021

Metabolic reprogramming toward oxidative phosphorylation identifies a therapeutic target for mantle cell lymphoma

scientific article published on 01 May 2019

The glutaminase activity of L-asparaginase is not required for anticancer activity against ASNS-negative cells.