Search filters

List of works by Terrence M Tumpey

2009 H1N1 swine flu: the 2010 perspective

scientific article published in September 2010

2009 pandemic H1N1 influenza virus elicits similar clinical course but differential host transcriptional response in mouse, macaque, and swine infection models

scientific article

5'PPP-RNA induced RIG-I activation inhibits drug-resistant avian H5N1 as well as 1918 and 2009 pandemic influenza virus replication

scientific article

A Single Base-Pair Change in 2009 H1N1 Hemagglutinin Increases Human Receptor Affinity and Leads to Efficient Airborne Viral Transmission in Ferrets

scientific article published on March 2, 2011

A broadly neutralizing human monoclonal antibody that recognizes a conserved, novel epitope on the globular head of the influenza H1N1 virus hemagglutinin

scientific article

A cationic liposome-DNA complexes adjuvant (JVRS-100) enhances the immunogenicity and cross-protective efficacy of pre-pandemic influenza A (H5N1) vaccine in ferrets.

scientific article

A live attenuated H1N1 M1 mutant provides broad cross-protection against influenza A viruses, including highly pathogenic A/Vietnam/1203/2004, in mice.

scientific article

A non-VH1-69 heterosubtypic neutralizing human monoclonal antibody protects mice against H1N1 and H5N1 viruses

scientific article

A novel A(H7N2) influenza virus isolated from a veterinarian caring for cats in a New York City animal shelter causes mild disease and transmits poorly in the ferret model

scientific article

A novel eight amino acid insertion contributes to the hemagglutinin cleavability and the virulence of a highly pathogenic avian influenza A (H7N3) virus in mice

scientific article published on 26 November 2015

A plant-produced H1N1 trimeric hemagglutinin protects mice from a lethal influenza virus challenge

scientific article published on January 7, 2013

A single amino acid substitution in 1918 influenza virus hemagglutinin changes receptor binding specificity.

scientific article

A single mutation in the PB1-F2 of H5N1 (HK/97) and 1918 influenza A viruses contributes to increased virulence

scientific article published on 5 October 2007

A two-amino acid change in the hemagglutinin of the 1918 influenza virus abolishes transmission

scientific article

A(H7N9) virus results in early induction of proinflammatory cytokine responses in both human lung epithelial and endothelial cells and shows increased human adaptation compared with avian H5N1 virus

scientific article published on 11 February 2015

An Insertion Mutation That Distorts Antibody Binding Site Architecture Enhances Function of a Human Antibody

scientific article

An avian influenza H7 DNA priming vaccine is safe and immunogenic in a randomized phase I clinical trial

scientific article published in June 2017

An early 'classical' swine H1N1 influenza virus shows similar pathogenicity to the 1918 pandemic virus in ferrets and mice.

scientific article

An influenza A virus (H7N9) anti-neuraminidase monoclonal antibody protects mice from morbidity without interfering with the development of protective immunity to subsequent homologous challenge

scientific article published on 6 September 2017

Antigenically Diverse Swine Origin H1N1 Variant Influenza Viruses Exhibit Differential Ferret Pathogenesis and Transmission Phenotypes

scientific article

Asparagine substitution at PB2 residue 701 enhances the replication, pathogenicity, and transmission of the 2009 pandemic H1N1 influenza A virus

scientific article

Assessment of Molecular, Antigenic, and Pathological Features of Canine Influenza A(H3N2) Viruses That Emerged in the United States

scientific article published on September 2017

Assessment of transmission, pathogenesis and adaptation of H2 subtype influenza viruses in ferrets

scientific article

Attaching zanamivir to a polymer markedly enhances its activity against drug-resistant strains of influenza a virus

scientific article

Avian influenza (H5N1) viruses isolated from humans in Asia in 2004 exhibit increased virulence in mammals

scientific article

Bifunctional polymeric inhibitors of human influenza A viruses.

scientific article

Cellular transcriptional profiling in influenza A virus-infected lung epithelial cells: the role of the nonstructural NS1 protein in the evasion of the host innate defense and its potential contribution to pandemic influenza

scientific article

Characterization of a highly pathogenic H5N1 avian influenza A virus isolated from duck meat.

scientific article

Characterization of highly pathogenic H5N1 avian influenza A viruses isolated from South Korea.

scientific article

Characterization of the murine Th2 response to immunization with liposomal M2e influenza vaccine

scientific article published on May 3, 2011

Characterization of the reconstructed 1918 Spanish influenza pandemic virus

scientific article

Comparative and analysis of H1N1 and H1N2 variant influenza viruses isolated from humans between 2011 and 2016

scientific article published on 29 October 2018

Comparative efficacy of hemagglutinin, nucleoprotein, and matrix 2 protein gene-based vaccination against H5N1 influenza in mouse and ferret

scientific article

Comparative immunogenicity and cross-clade protective efficacy of mammalian cell-grown inactivated and live attenuated H5N1 reassortant vaccines in ferrets

scientific article

Comparative susceptibility of chickens and turkeys to avian influenza A H7N2 virus infection and protective efficacy of a commercial avian influenza H7N2 virus vaccine

scientific article published in January 2004

Comparison of the Levels of Infectious Virus in Respirable Aerosols Exhaled by Ferrets Infected with Influenza Viruses Exhibiting Diverse Transmissibility Phenotypes

scientific article published on May 8, 2013

Comparison of traditional intranasal and aerosol inhalation inoculation of mice with influenza A viruses.

scientific article

Comparison of vaccines for induction of heterosubtypic immunity to influenza A virus: cold-adapted vaccine versus DNA prime-adenovirus boost strategies

scientific article published on 13 March 2008

Complexities in Ferret Influenza Virus Pathogenesis and Transmission Models

scientific article

Considerations Regarding Appropriate Sample Size for Conducting Ferret Transmission Experiments

scientific article published on August 1, 2013

Constitutively Expressed IFITM3 Protein in Human Endothelial Cells Poses an Early Infection Block to Human Influenza Viruses

scientific article

Contemporary North American influenza H7 viruses possess human receptor specificity: Implications for virus transmissibility.

scholarly article

Corrigendum: Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors

scientific article published in Nature

Cross-Reactive Antibody Responses to Novel H5Nx Influenza Viruses Following Homologous and Heterologous Prime-Boost Vaccination with a Prepandemic Stockpiled A(H5N1) Vaccine in Humans

scientific article published on September 2017

Cross-clade protective immune responses to influenza viruses with H5N1 HA and NA elicited by an influenza virus-like particle

scientific article

Cross-neutralization of 1918 and 2009 influenza viruses: role of glycans in viral evolution and vaccine design

scientific article published on March 2010

Cross-reactive antibody responses to the 2009 pandemic H1N1 influenza virus.

scientific article

Cytokine and chemokine profiles in lung tissues from fatal cases of 2009 pandemic influenza A (H1N1): role of the host immune response in pathogenesis.

scientific article

DNA priming and influenza vaccine immunogenicity: two phase 1 open label randomised clinical trials

scientific article published on 03 October 2011

DNA vaccine expressing conserved influenza virus proteins protective against H5N1 challenge infection in mice.

scientific article

Detection and Characterization of Clade 1 Reassortant H5N1 Viruses Isolated from Human Cases in Vietnam during 2013

scientific article

Determinants of glycan receptor specificity of H2N2 influenza A virus hemagglutinin

scientific article

Development of a Virosome Vaccine for Newcastle Disease Virus

scientific article published on July 1, 2003

Development of a high-throughput assay to detect antibody inhibition of low pH induced conformational changes of influenza virus hemagglutinin.

scientific article published on 27 June 2018

Diagnostic approach for differentiating infected from vaccinated poultry on the basis of antibodies to NS1, the nonstructural protein of influenza A virus.

scientific article

Differential microRNA expression and virulence of avian, 1918 reassortant, and reconstructed 1918 influenza A viruses

scientific article

Domestic poultry and SARS coronavirus, southern China

scientific article published on May 2004

Early and sustained innate immune response defines pathology and death in nonhuman primates infected by highly pathogenic influenza virus

scientific article

Early control of H5N1 influenza virus replication by the type I interferon response in mice.

scientific article published on 18 March 2009

Effect of D222G mutation in the hemagglutinin protein on receptor binding, pathogenesis and transmissibility of the 2009 pandemic H1N1 influenza virus

scientific article published on 22 September 2011

Effect of Priming With Seasonal Influenza A(H3N2) Virus on the Prevalence of Cross-Reactive Hemagglutination-Inhibition Antibodies to Swine-Origin A(H3N2) Variants

scientific article published on September 2017

Effect of receptor binding domain mutations on receptor binding and transmissibility of avian influenza H5N1 viruses

scientific article published on March 23, 2011

Effect of receptor binding specificity on the immunogenicity and protective efficacy of influenza virus A H1 vaccines

scientific article published on 30 July 2014

Efficacy of seasonal live attenuated influenza vaccine against virus replication and transmission of a pandemic 2009 H1N1 virus in ferrets

scientific article published on February 21, 2011

Elicitation of Anti-1918 Influenza Virus Immunity Early in Life Prevents Morbidity and Lower Levels of Lung Infection by 2009 Pandemic H1N1 Influenza Virus in Aged Mice

scientific article published on November 30, 2011

Enhanced virulence of clade 2.3.2.1 highly pathogenic avian influenza A H5N1 viruses in ferrets

scientific article

Environmental Conditions Affect Exhalation of H3N2 Seasonal and Variant Influenza Viruses and Respiratory Droplet Transmission in Ferrets

scientific article

Epitope-specific human influenza antibody repertoires diversify by B cell intraclonal sequence divergence and interclonal convergence

scientific article

Evaluation of influenza virus-like particles and Novasome adjuvant as candidate vaccine for avian influenza

scientific article

Evaluation of the antigenic relatedness and cross-protective immunity of the neuraminidase between human influenza A (H1N1) virus and highly pathogenic avian influenza A (H5N1) virus

scientific article published on 5 March 2014

Existing antivirals are effective against influenza viruses with genes from the 1918 pandemic virus.

scientific article

Experimental infection of pigs with the human 1918 pandemic influenza virus

scientific article

Generation and Characterization of Live Attenuated Influenza A(H7N9) Candidate Vaccine Virus Based on Russian Donor of Attenuation

scientific article published on 25 September 2015

Genetic analysis of avian influenza A viruses isolated from domestic waterfowl in live-bird markets of Hanoi, Vietnam, preceding fatal H5N1 human infections in 2004.

scientific article published on 4 July 2009

Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus

scientific article

Genomic analysis reveals age-dependent innate immune responses to severe acute respiratory syndrome coronavirus

scientific article published on 16 July 2008

Genomic profiling of tumor necrosis factor alpha (TNF-alpha) receptor and interleukin-1 receptor knockout mice reveals a link between TNF-alpha signaling and increased severity of 1918 pandemic influenza virus infection

scientific article

Global host immune response: pathogenesis and transcriptional profiling of type A influenza viruses expressing the hemagglutinin and neuraminidase genes from the 1918 pandemic virus.

scientific article

Glycan topology determines human adaptation of avian H5N1 virus hemagglutinin

scientific article published on 6 January 2008

Glycosylations in the globular head of the hemagglutinin protein modulate the virulence and antigenic properties of the H1N1 influenza viruses

scientific article

H5N1 VLP vaccine induced protection in ferrets against lethal challenge with highly pathogenic H5N1 influenza viruses.

scientific article

H5N1 and 1918 pandemic influenza virus infection results in early and excessive infiltration of macrophages and neutrophils in the lungs of mice.

scientific article

H5N1 pathogenesis studies in mammalian models

scientific article

H7N9 and other pathogenic avian influenza viruses elicit a three-pronged transcriptomic signature that is reminiscent of 1918 influenza virus and is associated with lethal outcome in mice

scientific article

Highly pathogenic avian influenza H5N1 viruses elicit an attenuated type i interferon response in polarized human bronchial epithelial cells

scientific article

Historical and clinical aspects of the 1918 H1N1 pandemic in the United States

scientific article published on 16 November 2018

Human HA and polymerase subunit PB2 proteins confer transmission of an avian influenza virus through the air.

scientific article

Human antibodies that neutralize respiratory droplet transmissible H5N1 influenza viruses

scientific article

Human monoclonal antibodies to pandemic 1957 H2N2 and pandemic 1968 H3N2 influenza viruses

scientific article

Human pulmonary microvascular endothelial cells support productive replication of highly pathogenic avian influenza viruses: possible involvement in the pathogenesis of human H5N1 virus infection

scientific article

Hydrophobic polycationic coatings inactivate wild-type and zanamivir- and/or oseltamivir-resistant human and avian influenza viruses

scientific article published on 31 October 2007

Immunity to influenza: the challenges of protecting an aging population.

scientific article

Impact of prior seasonal H3N2 influenza vaccination or infection on protection and transmission of emerging variants of influenza A(H3N2)v virus in ferrets.

scientific article

Implication of Inflammatory Macrophages, Nuclear Receptors, and Interferon Regulatory Factors in Increased Virulence of Pandemic 2009 H1N1 Influenza A Virus after Host Adaptation

scientific article published on April 24, 2012

Importance of 1918 virus reconstruction to current assessments of pandemic risk

scientific article published on 22 August 2018

Inducible nitric oxide contributes to viral pathogenesis following highly pathogenic influenza virus infection in mice

scientific article

Induction of broadly neutralizing H1N1 influenza antibodies by vaccination

scientific article

Infection With Highly Pathogenic H7 Influenza Viruses Results in an Attenuated Proinflammatory Cytokine and Chemokine Response Early After Infection

scientific article published on January 1, 2011

Infection and replication of influenza virus at the ocular surface

scientific article published on 10 January 2018

Infection of Cultured Mammalian Cells with Aerosolized Influenza Virus

scientific article published on 01 January 2018

Infection of lung epithelial cells with pandemic 2009 A(H1N1) influenza viruses reveals isolate-specific differences in infectivity and host cellular responses

scientific article

Influence of Immune Priming and Egg Adaptation in the Vaccine on Antibody Responses to Circulating A(H1N1)pdm09 Viruses After Influenza Vaccination in Adults

article

Influenza A virus transmission: contributing factors and clinical implications

scientific article published on December 9, 2010

Influenza Virus H5 DNA Vaccination Is Immunogenic by Intramuscular and Intradermal Routes in Humans

scientific article published on September 5, 2012

Influenza virus aerosol exposure and analytical system for ferrets

scientific article

Influenza virus infection causes global RNAPII termination defects

Influenza virus infection increases p53 activity: role of p53 in cell death and viral replication

scientific article

Influenza virus infectivity and virulence following ocular-only aerosol inoculation of ferrets

scientific article

Influenza virus respiratory infection and transmission following ocular inoculation in ferrets

scientific article

Influenza virus-like particle can accommodate multiple subtypes of hemagglutinin and protect from multiple influenza types and subtypes

scientific article

Influenza virus-like particles comprised of the HA, NA, and M1 proteins of H9N2 influenza virus induce protective immune responses in BALB/c mice.

scientific article

Innovations in modeling influenza virus infections in the laboratory

scientific article published on April 19, 2012

Integration of clinical data, pathology, and cDNA microarrays in influenza virus-infected pigtailed macaques (Macaca nemestrina)

scientific article published in October 2004

Integrative deep sequencing of the mouse lung transcriptome reveals differential expression of diverse classes of small RNAs in response to respiratory virus infection

scientific article published on 15 November 2011

Intranasal vaccination with 1918 influenza virus-like particles protects mice and ferrets from lethal 1918 and H5N1 influenza virus challenge.

scientific article

Intranasal vaccination with H5, H7 and H9 hemagglutinins co-localized in a virus-like particle protects ferrets from multiple avian influenza viruses

scientific article published on April 22, 2013

Isolation and characterization of avian influenza viruses, including highly pathogenic H5N1, from poultry in live bird markets in Hanoi, Vietnam, in 2001.

scientific article

Kinetics of viral replication and induction of host responses in ferrets differs between ocular and intranasal routes of inoculation

scientific article published on February 13, 2013

Lack of transmission of H5N1 avian-human reassortant influenza viruses in a ferret model

scientific article

Lethal dissemination of H5N1 influenza virus is associated with dysregulation of inflammation and lipoxin signaling in a mouse model of infection

scientific article

Local innate immune responses and influenza virus transmission and virulence in ferrets

scientific article published on 9 December 2011

Macaque proteome response to highly pathogenic avian influenza and 1918 reassortant influenza virus infections

scientific article

Mammalian Pathogenesis and Transmission of Avian Influenza A(H7N9) Viruses, Tennessee, USA, 2017.

scientific article published in January 2018

Mammalian Pathogenesis and Transmission of H7N9 Influenza Viruses from Three Waves, 2013-2015

scientific article

Mammalian models for the study of H7 virus pathogenesis and transmission.

scientific article

Matrix protein 2 vaccination and protection against influenza viruses, including subtype H5N1

scientific article published on March 2007

Mice lacking both TNF and IL-1 receptors exhibit reduced lung inflammation and delay in onset of death following infection with a highly virulent H5N1 virus

scientific article

MicroRNA expression and virulence in pandemic influenza virus-infected mice.

scientific article

Molecular signatures associated with Mx1-mediated resistance to highly pathogenic influenza virus infection: mechanisms of survival

scientific article

Mono- and quadri-subtype virus-like particles (VLPs) containing H10 subtype elicit protective immunity to H10 influenza in a ferret challenge model

scientific article published on 20 September 2016

Multi-clade H5N1 virus-like particles: Immunogenicity and protection against H5N1 virus and effects of beta-propiolactone

scholarly article by Peter Pushko et al published 5 July 2018 in Vaccine

Multiple genes contribute to the virulent phenotype observed in ferrets of an H5N1 influenza virus isolated from Thailand in 2004

scientific article published on March 8, 2011

N-Linked Glycosylation of the Hemagglutinin Protein Influences Virulence and Antigenicity of the 1918 Pandemic and Seasonal H1N1 Influenza A Viruses

scientific article published on June 5, 2013

NS-based live attenuated H1N1 pandemic vaccines protect mice and ferrets

scientific article

Naturally occurring human monoclonal antibodies neutralize both 1918 and 2009 pandemic influenza A (H1N1) viruses.

scientific article

Neuraminidase-based recombinant virus-like particles protect against lethal avian influenza A(H5N1) virus infection in ferrets

scientific article

Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors.

scientific article

Novel pandemic influenza A(H1N1) viruses are potently inhibited by DAS181, a sialidase fusion protein.

scientific article

Ocular Tropism of Respiratory Viruses

scientific article published on March 1, 2013

Ocular infection of mice with influenza A (H7) viruses: a site of primary replication and spread to the respiratory tract

scientific article published on 20 May 2009

Ocular tropism of influenza A viruses: identification of H7 subtype-specific host responses in human respiratory and ocular cells

scientific article

Oseltamivir inhibits H7 influenza virus replication in mice inoculated by the ocular route

scientific article published on 12 December 2011

Oseltamivir inhibits influenza virus replication and transmission following ocular-only aerosol inoculation of ferrets

scientific article published on 2 July 2015

P58(IPK): a novel "CIHD" member of the host innate defense response against pathogenic virus infection.

scientific article

PB1-F2 expression by the 2009 pandemic H1N1 influenza virus has minimal impact on virulence in animal models

scientific article

Past, present, and possible future human infection with influenza virus A subtype H7.

scientific article published on June 2009

Pathogenesis and Transmission Assessments of Two H7N8 Influenza A Viruses Recently Isolated from Turkey Farms in Indiana Using Mouse and Ferret Models

scientific article published on 28 September 2016

Pathogenesis and Transmission of Genetically Diverse Swine-Origin H3N2 Variant Influenza A Viruses from Multiple Lineages Isolated in the United States, 2011-2016

article

Pathogenesis and Transmission of Novel Highly Pathogenic Avian Influenza H5N2 and H5N8 Viruses in Ferrets and Mice

scientific article

Pathogenesis and Transmission of Triple-Reassortant Swine H1N1 Influenza Viruses Isolated before the 2009 H1N1 Pandemic

scientific article published on December 1, 2010

Pathogenesis and transmission of avian influenza A (H7N9) virus in ferrets and mice

scientific article published on July 10, 2013

Pathogenesis and transmission of swine origin A(H3N2)v influenza viruses in ferrets

scientific article published on February 21, 2012

Pathogenesis of 1918 pandemic and H5N1 influenza virus infections in a guinea pig model: antiviral potential of exogenous alpha interferon to reduce virus shedding

scientific article

Pathogenesis of avian influenza (H7) virus infection in mice and ferrets: enhanced virulence of Eurasian H7N7 viruses isolated from humans

scientific article

Pathogenesis of emerging avian influenza viruses in mammals and the host innate immune response.

scientific article

Pathogenesis of pandemic influenza A (H1N1) and triple-reassortant swine influenza A (H1) viruses in mice.

scientific article

Pathogenesis, Transmissibility, and Ocular Tropism of a Highly Pathogenic Avian Influenza A (H7N3) Virus Associated with Human Conjunctivitis

scientific article published on March 13, 2013

Pathogenesis, Transmissibility, and Tropism of a Highly Pathogenic Avian Influenza A(H7N7) Virus Associated With Human Conjunctivitis in Italy, 2013.

scientific article published on September 2017

Pathogenicity and immunogenicity of influenza viruses with genes from the 1918 pandemic virus.

scientific article

Pathogenicity of influenza viruses with genes from the 1918 pandemic virus: functional roles of alveolar macrophages and neutrophils in limiting virus replication and mortality in mice

scientific article

Pathogenicity testing of influenza candidate vaccine viruses in the ferret model

scientific article

Pause on avian flu transmission research

scientific article published on January 2012

Phase 1 study of pandemic H1 DNA vaccine in healthy adults

scientific article

Preexisting Immunity, Not Frailty Phenotype, Predicts Influenza Postvaccination Titers among Older Veterans

scientific article published on 18 January 2017

Preparation of genetically engineered A/H5N1 and A/H7N1 pandemic vaccine viruses by reverse genetics in a mixture of Vero and chicken embryo cells.

scientific article

Preparation of quadri-subtype influenza virus-like particles using bovine immunodeficiency virus gag protein

scientific article published on 31 October 2015

Prophylactic and therapeutic efficacy of avian antibodies against influenza virus H5N1 and H1N1 in mice

scientific article

Protection against H1, H5, H6 and H9 influenza A infection with liposomal matrix 2 epitope vaccines.

scientific article

Protection against lethal influenza virus challenge by RNA interference in vivo.

scholarly article

Protection against multiple influenza A subtypes by vaccination with highly conserved nucleoprotein.

scientific article

Protective immunity to lethal challenge of the 1918 pandemic influenza virus by vaccination.

scientific article

Quantitative biochemical rationale for differences in transmissibility of 1918 pandemic influenza A viruses.

scientific article

Receptor specificity and transmission of H2N2 subtype viruses isolated from the pandemic of 1957.

scientific article

Recombinant H1N1 virus-like particle vaccine elicits protective immunity in ferrets against the 2009 pandemic H1N1 influenza virus

scientific article

Recombinant H7 hemagglutinin forms subviral particles that protect mice and ferrets from challenge with H7N9 influenza virus

scientific article

Recombinant virus-like particles elicit protective immunity against avian influenza A(H7N9) virus infection in ferrets.

scientific article

Reconstruction of the 1918 pandemic influenza virus: how revealing the molecular secrets of the virus responsible for the worst pandemic in recorded history can guide our response to future influenza pandemics.

scientific article

Resurrected pandemic influenza viruses.

scientific article

Risk Assessment of Fifth-Wave H7N9 Influenza A Viruses in Mammalian Models.

scientific article published on 10 December 2018

Role for macrophage inflammatory protein 2 (MIP-2), MIP-1alpha, and interleukin-1alpha in the delayed-type hypersensitivity response to viral antigen

scientific article

Role of H7 hemagglutinin in murine infectivity of influenza viruses following ocular inoculation

scientific article published on 10 December 2016

Role of host cytokine responses in the pathogenesis of avian H5N1 influenza viruses in mice

scientific article published on 20 December 2006

Seasonal Trivalent Inactivated Influenza Vaccine Does Not Protect against Newly Emerging Variants of Influenza A (H3N2v) Virus in Ferrets

scientific article published on October 31, 2012

Seasonal trivalent inactivated influenza vaccine protects against 1918 Spanish influenza virus infection in ferrets

scientific article

Simvastatin and oseltamivir combination therapy does not improve the effectiveness of oseltamivir alone following highly pathogenic avian H5N1 influenza virus infection in mice

scientific article published in March 2013

Single gene reassortants identify a critical role for PB1, HA, and NA in the high virulence of the 1918 pandemic influenza virus

scientific article

Single-Dose Mucosal Immunization with a Candidate Universal Influenza Vaccine Provides Rapid Protection from Virulent H5N1, H3N2 and H1N1 Viruses

scientific article published on October 4, 2010

Sowing the Seeds of a Pandemic? Mammalian Pathogenicity and Transmissibility of H1 Variant Influenza Viruses from the Swine Reservoir

Stockpiled pre-pandemic H5N1 influenza virus vaccines with AS03 adjuvant provide cross-protection from H5N2 clade 2.3.4.4 virus challenge in ferrets

scientific article

Swine-Origin H1 Influenza Viruses Isolated from Humans Exhibit Sustained Infectivity in an Aerosol State

scientific article published in 2019

Synthetic viruses: a new opportunity to understand and prevent viral disease

scientific article

The 1918 flu, 100 years later

scientific article

The 2009 Pandemic H1N1 and Triple-Reassortant Swine H1N1 Influenza Viruses Replicate Efficiently but Elicit an Attenuated Inflammatory Response in Polarized Human Bronchial Epithelial Cells

scientific article published on November 3, 2010

The Mx1 gene protects mice against the pandemic 1918 and highly lethal human H5N1 influenza viruses.

scientific article

The NS1 protein of the 1918 pandemic influenza virus blocks host interferon and lipid metabolism pathways

scientific article

The alpha/beta interferon receptor provides protection against influenza virus replication but is dispensable for inflammatory response signaling

scientific article

The development of vaccine viruses against pandemic A(H1N1) influenza

scientific article published on February 17, 2011

The draft genome sequence of the ferret (Mustela putorius furo) facilitates study of human respiratory disease

scientific article (publication date: December 2014)

The eyes have it: influenza virus infection beyond the respiratory tract

scientific article published on 21 February 2018

The ferret as a model organism to study influenza A virus infection

scientific article published on 02 August 2011

The guinea pig as a transmission model for human influenza viruses

scientific article

Transcriptomic characterization of the novel avian-origin influenza A (H7N9) virus: specific host response and responses intermediate between avian (H5N1 and H7N7) and human (H3N2) viruses and implications for treatment options

scientific article

Transforming growth factor-β: activation by neuraminidase and role in highly pathogenic H5N1 influenza pathogenesis

scientific article

Transmission studies resume for avian flu.

scientific article

Tropism and Infectivity of Influenza Virus, Including Highly Pathogenic Avian H5N1 Virus, in Ferret Tracheal Differentiated Primary Epithelial Cell Cultures

scientific article published on December 19, 2012

Tropism of H7N9 influenza viruses in the human respiratory tract

scientific article published on 25 July 2013

Use of animal models to understand the pandemic potential of highly pathogenic avian influenza viruses.

scientific article

Use of highly pathogenic avian influenza A(H5N1) gain-of-function studies for molecular-based surveillance and pandemic preparedness

scientific article

Vaccination focusing immunity on conserved antigens protects mice and ferrets against virulent H1N1 and H5N1 influenza A viruses

scientific article published in September 2009

Vaccination with virus-like particles containing H5 antigens from three H5N1 clades protects chickens from H5N1 and H5N8 influenza viruses

scientific article published on 8 February 2016

Virus-like particles displaying H5, H7, H9 hemagglutinins and N1 neuraminidase elicit protective immunity to heterologous avian influenza viruses in chickens

scientific article

What can we learn from reconstructing the extinct 1918 pandemic influenza virus?

scientific article

Zanamivir conjugated to poly-L-glutamine is much more active against influenza viruses in mice and ferrets than the drug itself

scientific article published on 25 September 2013