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List of works by Annette Oxenius

A controlled trial of granulocyte macrophage-colony stimulating factor during interruption of HAART.

scientific article published on July 2003

A novel Th cell epitope of Candida albicans mediates protection from fungal infection

scientific article published on 23 April 2012

A novel role for neutrophils as critical activators of NK cells

scientific article published on 01 November 2008

A prospective trial of structured treatment interruptions in human immunodeficiency virus infection

scientific article published in May 2003

A simple method for evaluating the rejection of grafted spleen cells by flow cytometry and tracing adoptively transferred cells by light microscopy ⬇️

scientific article published on August 22, 1997

AIDS: the evolving story

scientific article published on 01 April 2000

Absence of Cross-Presenting Cells in the Salivary Gland and Viral Immune Evasion Confine Cytomegalovirus Immune Control to Effector CD4 T Cells ⬇️

scientific article published on August 25, 2011

Adenovirus vector vaccination reprograms pulmonary fibroblastic niches to support protective inflating memory CD8 T cells

Adoptive transfer of cytomegalovirus‐specific effector CD4+T cells provides antiviral protection from murine CMV infection ⬇️

scientific article published on August 26, 2013

Advances in cytomegalovirus (CMV) biology and its relationship to health, diseases, and aging

scientific article published on 11 March 2020

Antagonism of interferon signaling by fibroblast growth factors promotes viral replication

scientific article published on 27 July 2020

Antibodies protect against intracellular bacteria by Fc receptor-mediated lysosomal targeting.

scientific article

Antibody-Fc receptor interactions in protection against intracellular pathogens.

scientific article published on 17 March 2011

Antigen amount dictates CD8+ T-cell exhaustion during chronic viral infection irrespective of the type of antigen presenting cell

scientific article published on 06 August 2012

Antigen-Dependent and -Independent Mechanisms of T and B Cell Hyperactivation during Chronic HIV-1 Infection ⬇️

scientific article published on August 17, 2011

Antiviral B cell memory in the absence of mature follicular dendritic cell networks and classical germinal centers in TNFR1-/- mice

scientific article

Assessment of legionella-specific immunity in mice

scientific article

Batf3 transcription factor‐dependent DC subsets in murine CMV infection: Differential impact on T‐cell priming and memory inflation ⬇️

scientific article published on August 4, 2011

Brain-resident memory CD8+ T cells induced by congenital CMV infection prevent brain pathology and virus reactivation.

scientific article published on 3 March 2018

CD4 T Cell Responses in Latent and Chronic Viral Infections ⬇️

scientific article published on May 13, 2013

CD4 T Cell-Mediated Immune Control of Cytomegalovirus Infection in Murine Salivary Glands

CD4(+) T cell subsets during virus infection. Protective capacity depends on effector cytokine secretion and on migratory capability

scientific article

CD4+ T cell responses in mice lacking MHC class II molecules specifically on B cells

scientific article published on 01 November 1998

CD4+ T-Cell Induction and Effector Functions: A Comparison of Immunity against Soluble Antigens and Viral Infections

scientific article published on 01 January 1998

CD4+ T-cell help is required for effective CD8+ T cell-mediated resolution of acute viral hepatitis in mice

scientific article published on 21 January 2014

CD4+ T-cell-epitope escape mutant virus selected in vivo

scientific article published in July 2001

CD40-CD40 ligand interactions are critical in T-B cooperation but not for other anti-viral CD4+ T cell functions

scientific article

CD8 T‐cell diversification: Asymmetric cell division and its functional implications

CD8+ T cells are activated in an antigen-independent manner in HIV-infected individuals

scientific article published on 20 January 2014

CD85k Contributes to Regulatory T Cell Function in Chronic Viral Infections

scientific article published on 22 December 2020

Chronic viral infections impinge on naive bystander CD8 T cells

scientific article published on 26 March 2020

Chronic virus infection compromises memory bystander T cell function in an IL-6/STAT1-dependent manner

scientific article published on 11 February 2019

Clonally Expanded Virus-Specific CD8 T Cells Acquire Diverse Transcriptional Phenotypes During Acute, Chronic, and Latent Infections

scientific article published on 02 February 2022

Comparing the kinetics of NK cells, CD4, and CD8 T cells in murine cytomegalovirus infection

scientific article published on 22 June 2011

Comparison of activation versus induction of unresponsiveness of virus-specific CD4+ and CD8+ T cells upon acute versus persistent viral infection

scientific article

Comparison of cytotoxic T lymphocyte efficacy in acute and persistent lymphocytic choriomeningitis virus infection ⬇️

scientific article published on March 30, 2011

Comparison of methods for phylogenetic B-cell lineage inference using time-resolved antibody repertoire simulations (AbSim).

scientific article published on 31 August 2017

Complete mapping of a novel HLA A*6801-restricted HIV-1 Tat epitope directly with a rapid modified enzyme-linked immunospot assay

scientific article published on 01 June 2002

CpG-containing oligonucleotides are efficient adjuvants for induction of protective antiviral immune responses with T-cell peptide vaccines.

scientific article

Cross-staining of cytotoxic T lymphocyte populations with peptide-MHC class I multimers of natural HIV-1 variant antigens

article

Cutting edge: distinct roles for T help and CD40/CD40 ligand in regulating differentiation of proliferation-competent memory CD8+ T cells

scientific article published on 01 August 2004

Cytopath: Simulation-based inference of differentiation trajectories from RNA velocity fields

Cytotoxic T lymphocyte responses to human immunodeficiency virus: control and escape.

scientific article

Defective T helper response of hepatocyte-stimulated CD4 T cells impairs antiviral CD8 response and viral clearance

scientific article published on 14 September 2007

Delay of HIV-1 rebound after cessation of antiretroviral therapy through passive transfer of human neutralizing antibodies

article

Dendritic cells primed with a chimeric plasmid containing HIV-1-gag associated with lysosomal-associated protein-1 (LAMP/gag) is a potential therapeutic vaccine against HIV.

scientific article published on 19 May 2016

Differential role of IL-2R signaling for CD8+ T cell responses in acute and chronic viral infections

scientific article published in June 2007

Differential survival of cytotoxic T cells and memory cell precursors

scientific article published in March 2007

Direct activation of antigen-presenting cells is required for CD8+ T-cell priming and tumor vaccination

scientific article

Direct ex vivo analysis reveals distinct phenotypic patterns of HIV-specific CD8(+) T lymphocyte activation in response to therapeutic manipulation of virus load

scientific article published in April 2001

Direct ex vivo measurement of CD8(+) T-lymphocyte responses to human parvovirus B19.

scientific article published on January 2001

Discordant outcomes following failure of antiretroviral therapy are associated with substantial differences in human immunodeficiency virus-specific cellular immunity

scientific article

Dissecting the contribution of IgG subclasses in restricting airway infection with Legionella pneumophila

scientific article published on 10 September 2014

Disseminated and sustained HIV infection in CD34+ cord blood cell-transplanted Rag2-/-gamma c-/- mice

scholarly article

Distribution of functional HIV-specific CD8 T lymphocytes between blood and secondary lymphoid organs after 8-18 months of antiretroviral therapy in acutely infected patients

scientific article published on 01 September 2001

Early highly active antiretroviral therapy for acute HIV-1 infection preserves immune function of CD8+ and CD4+ T lymphocytes

scientific article

Early primed KLRG1- CMV-specific T cells determine the size of the inflationary T cell pool.

scientific article published on 13 May 2019

Effective T-cell responses select human immunodeficiency virus mutants and slow disease progression

scientific article published on 4 April 2007

Effects of retroviral protease inhibitors on proteasome function and processing of HIV-derived MHC class I-restricted cytotoxic T lymphocyte epitopes.

scientific article published in July 2001

Emergence of polyfunctional CD8+ T cells after prolonged suppression of human immunodeficiency virus replication by antiretroviral therapy

scientific article

Entry and transcription as key determinants of differences in CD4 T-cell permissiveness to human immunodeficiency virus type 1 infection.

scientific article published on October 2004

Estimating the In Vivo Killing Efficacy of Cytotoxic T Lymphocytes across Different Peptide-MHC Complex Densities

scientific article published on May 2015

Exhausted CD8+ T cells exhibit low and strongly inhibited TCR signaling during chronic LCMV infection

scientific article published on 08 September 2020

Expansion of protective CD8+ T-cell responses driven by recombinant cytomegaloviruses

scientific article published on March 2004

Failure to detect xenotropic murine leukemia virus-related virus in blood of individuals at high risk of blood-borne viral infections

scientific article

Fate trajectories of CD8 + T cells in chronic LCMV infection

Formation of TCR dimers/trimers as a crucial step for T cell activation ⬇️

scientific article published on August 1, 1998

From crucial to negligible: Functional CD8+T‐cell responses and their dependence on CD4+T‐cell help ⬇️

scientific article published on May 1, 2012

Fuel and brake of memory T cell inflation

scientific article published on 09 March 2019

Functional and biophysical characterization of an HLA-A*6801-restricted HIV-specific T cell receptor

scientific article

Functional in vivo MHC class II loading by endogenously synthesized glycoprotein during viral infection

scientific article published in June 1997

Functional properties and lineage relationship of CD8+ T cell subsets identified by expression of IL-7 receptor alpha and CD62L.

scientific article published in October 2005

Generation and in vivo characterization of a novel high-affinity human antibody targeting carcinoembryonic antigen

Guidelines for the use of flow cytometry and cell sorting in immunological studies

scientific article published on October 2017

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

scientific article published on 01 October 2019

Gut commensal microbes do not represent a dominant antigenic source for continuous CD4+ T-cell activation during HIV-1 infection

scientific article published on 8 September 2015

HIV preferentially infects HIV-specific CD4+ T cells

scientific article

HIV replication elicits little cytopathic effects in vivo: analysis of surrogate markers for virus production, cytotoxic T cell response and infected cell death

scientific article published in September 2006

HIV-1 replication activates CD4+ T cells with specificities for persistent herpes viruses

scientific article

HIV-1-specific CD4+ T lymphocyte turnover and activation increase upon viral rebound

scientific article

HIV-specific cellular immune response is inversely correlated with disease progression as defined by decline of CD4+ T cells in relation to HIV RNA load

scientific article published on 17 March 2004

How chronic viral infections impact on antigen-specific T-cell responses

scientific article published on March 2010

Human immunodeficiency virus-specific CD8(+) T-cell responses do not predict viral growth and clearance rates during structured intermittent antiretroviral therapy

scientific article

Humoral immunity to HIV-1: kinetics of antibody responses in chronic infection reflects capacity of immune system to improve viral set point

scientific article published on 8 June 2004

IL-10 suppression of NK/DC crosstalk leads to poor priming of MCMV-specific CD4 T cells and prolonged MCMV persistence.

scientific article

IL-12 is not required for induction of type 1 cytokine responses in viral infections

scientific article published on 01 January 1999

IL-21 restricts virus-driven Treg cell expansion in chronic LCMV infection.

scientific article

IL-21R on T cells is critical for sustained functionality and control of chronic viral infection

scientific article

Identification of protective B cell antigens of Legionella pneumophila

scientific article published on 13 June 2012

IgM Antibody Repertoire Fingerprints in Mice Are Personalized but Robust to Viral Infection Status

scientific article published on 28 May 2020

Immediate cytotoxicity but not degranulation distinguishes effector and memory subsets of CD8+ T cells

scientific article

Immune responses in the absence of costimulation: viruses know the trick

scientific article published in December 1998

Immune senescence: relative contributions of age and cytomegalovirus infection

scientific article

Immunofluorescence Imaging of Legionella Infection In Vitro ⬇️

scientific article published on January 1, 2013

Impact of antigen specificity on CD4+ T cell activation in chronic HIV-1 infection

scientific article published on 25 February 2013

Impaired NFAT nuclear translocation results in split exhaustion of virus-specific CD8+ T cell functions during chronic viral infection.

scholarly article

Inducible costimulator protein (ICOS) controls T helper cell subset polarization after virus and parasite infection

scientific article published on July 2000

Induction and protective role of antibodies in Legionella pneumophila infection

scientific article published on 01 December 2007

Inflammasome activation and IL-1β target IL-1α for secretion as opposed to surface expression

scientific article published on 17 October 2011

Influenza- and MCMV-induced memory CD8 T cells control respiratory vaccinia virus infection despite residence in distinct anatomical niches

Innate Instruction of CD4+ T Cell Immunity in Respiratory Bacterial Infection ⬇️

scientific article published on June 20, 2012

Inter- and intraspecies comparison of phylogenetic fingerprints and sequence diversity of immunoglobulin variable genes

scientific article published on 04 May 2020

Intercrypt sentinel macrophages tune antibacterial NF-κB responses in gut epithelial cells via TNF

Interleukin 2: from immunostimulation to immunoregulation and back again

scientific article

Investigating the Dynamics of MCMV-Specific CD8+ T Cell Responses in Individual Hosts

scientific article published on 19 June 2019

Kinetic and mechanistic requirements for helping CD8 T cells

scientific article published in February 2008

LCMV-specific CD4 T cell dependent polyclonal B-cell activation upon persistent viral infection is short lived and extrafollicular

scientific article published on 27 November 2019

Landornamides, antiviral ornithine-containing ribosomal peptides discovered by proteusin mining

scientific article published on 12 March 2020

Landscape of Exhausted Virus-Specific CD8 T Cells in Chronic LCMV Infection

scientific article published on 01 August 2020

Light-mediated discovery of surfaceome nanoscale organization and intercellular receptor interaction networks

scientific article published on 02 December 2021

Locally confined IFN γ production by CD4 + T cells provides niches for murine cytomegalovirus replication in the salivary gland

Long-lived memory CD8+ T cells are programmed by prolonged antigen exposure and low levels of cellular activation

scientific article published in April 2006

Loss of Viral Control in Early HIV‐1 Infection Is Temporally Associated with Sequential Escape from CD8+T Cell Responses and Decrease in HIV–1–Specific CD4+and CD8+T Cell Frequencies

article

Low human immunodeficiency virus envelope diversity correlates with low in vitro replication capacity and predicts spontaneous control of plasma viremia after treatment interruptions

scientific article

MHC class I-restricted killing of neurons by virus-specific CD8+ T lymphocytes is effected through the Fas/FasL, but not the perforin pathway,.

scientific article published in December 2000

MHC class II proteins mediate cross-species entry of bat influenza viruses

scientific article published in Nature

Macrophage and T cell produced IL-10 promotes viral chronicity

scientific article

Mapping the drivers of within-host pathogen evolution using massive data sets

scientific article published on 09 July 2019

Mapping the drivers of within-host pathogen evolution using massive data sets

Memory CD8 T cell inflation vs tissue-resident memory T cells: Same patrollers, same controllers?

scientific article

Memory T cells: total recall or just a sense of déjà vu?

scientific article

Memory inflation: continuous accumulation of antiviral CD8+ T cells over time

scientific article published in February 2003

Modulation of asymmetric cell division as a mechanism to boost CD8+ T cell memory

scientific article published on 01 April 2019

Mouse-specific but infection-unspecific IgM repertoire fingerprint following viral infection

MyD88-dependent IFN-gamma production by NK cells is key for control of Legionella pneumophila infection

article

NK cells negatively regulate CD8 T cells via natural cytotoxicity receptor (NCR) 1 during LCMV infection

scientific article published on 17 April 2019

NK cells regulating T cell responses: mechanisms and outcome

scientific article published on January 2015

Neutrophil and Alveolar Macrophage-Mediated Innate Immune Control of Legionella pneumophila Lung Infection via TNF and ROS

scientific article

No evidence for competition between cytotoxic T-lymphocyte responses in HIV-1 infection.

scientific article

Non-Hematopoietic Cells in Lymph Nodes Drive Memory CD8 T Cell Inflation during Murine Cytomegalovirus Infection ⬇️

scientific article published on October 27, 2011

Non-neutralizing antibodies protect against chronic LCMV infection by promoting infection of inflammatory monocytes in mice

Nonhematopoietic Cells Are Key Players in Innate Control of Bacterial Airway Infection

scientific article published on 26 January 2011

Non‐neutralizing antibodies protect from chronic LCMV infection independently of activating FcγR or complement ⬇️

scientific article published on July 15, 2013

Novel CD8+ T cell antagonists based on beta 2-microglobulin.

scientific article published on 25 March 2002

O Mannosylation of alpha-dystroglycan is essential for lymphocytic choriomeningitis virus receptor function

scientific article

On the role of the inhibitory receptor LAG-3 in acute and chronic LCMV infection

scientific article

Peptide-induced T cell receptor down-regulation on naive T cells predicts agonist/partial agonist properties and strictly correlates with T cell activation

scientific article published on 01 September 1997

Peroxiredoxin 6 is required for blood vessel integrity in wounded skin

scientific article

Phenotypic determinism and stochasticity in antibody repertoires of clonally expanded plasma cells

scientific article published on 29 April 2022

Platypus: an open-access software for integrating lymphocyte single-cell immune repertoires with transcriptomes

scientific article published on 14 April 2021

Post-translational modification of {alpha}-dystroglycan is not critical for lymphocytic choriomeningitis virus receptor function in vivo

scientific article published in November 2008

Presentation of endogenous viral proteins in association with major histocompatibility complex class II: on the role of intracellular compartmentalization, invariant chain and the TAP transporter system

scientific article published on December 1995

Profiling Virus-Specific Tcf1+ T Cell Repertoires During Acute and Chronic Viral Infection

scientific article published on 29 May 2020

Profiling virus-specific Tcf1+ T cell repertoires during acute and chronic viral infection

Programmed death 1 protects from fatal circulatory failure during systemic virus infection of mice.

scientific article

Publisher Correction: Tumor-necrosis factor impairs CD4+ T cell-mediated immunological control in chronic viral infection

scientific article published on 03 July 2020

Quantifiable cytotoxic T lymphocyte responses and HLA-related risk of progression to AIDS

scholarly article

Quantitative and Qualitative Analysis of Humoral Immunity Reveals Continued and Personalized Evolution in Chronic Viral Infection

scientific article published on 01 January 2020

Rapid expansion of Treg cells protects from collateral colitis following a viral trigger

scientific article published on 23 March 2020

Recall proliferation potential of memory CD8+ T cells and antiviral protection

scientific article published on 01 October 2005

Recognition and Regulation of T Cells by NK Cells

scientific article

Regulation of antiviral T cell responses by type I interferons

scientific article published on 20 March 2015

Relevance of HIV-1-specific CD4+ helper T-cell responses during structured treatment interruptions in patients with CD4+ T-cell nadir above 400/mm3.

scientific article published in July 2004

Residual HIV-specific CD4 and CD8 T cell frequencies after prolonged antiretroviral therapy reflect pretreatment plasma virus load

scientific article published in November 2002

Retracted: The protein LEM promotes CD8⁺ T cell immunity through effects on mitochondrial respiration

retracted scientific article

Reversal of chronic to resolved infection by IL‐10 blockade is LCMV strain dependent ⬇️

scientific article published on January 25, 2013

Role of mitotic diffusion barriers in regulating the asymmetric division of activated CD8 T cells

Salivary gland resident APCs are Flt3L- and CCR2-independent macrophage-like cells incapable of cross-presentation

scientific article published on 23 December 2013

Sarcoma Eradication by Doxorubicin and Targeted TNF Relies upon CD8+ T-cell Recognition of a Retroviral Antigen

scientific article

Selection of a Broad Repertoire of CD4+ T Cells in H-2Ma0/0 Mice ⬇️

scientific article published on 01 August 1997

Similar Ligand Densities Required for Restimulation and Effector Function of Cytotoxic T Cells ⬇️

scientific article published on July 10, 1997

Single B cell technologies for monoclonal antibody discovery

Stimulation of HIV-specific cellular immunity by structured treatment interruption fails to enhance viral control in chronic HIV infection

scientific article

Structured treatment interruptions in HIV infection: benefit or disappointment?

scientific article published in June 2003

Superior induction and maintenance of protective CD8 T cells in mice infected with mouse cytomegalovirus vector expressing RAE-1γ.

scientific article published on 19 September 2013

Sustained T follicular helper cell response is essential for control of chronic viral infection.

scientific article

Systemic antibody responses to gut commensal bacteria during chronic HIV-1 infection

scientific article published on 21 April 2011

Systemic antibody responses to gut microbes in health and disease

scientific article published on January 2012

T cell development in CD8-/- mice. Thymic positive selection is biased toward the helper phenotype.

scientific article published in October 1995

T cell memory in the context of persistent herpes viral infections

scientific article

T cell responses to cytomegalovirus

scientific article published on 25 April 2016

T lymphocyte responses against human parvovirus B19: small virus, big response

scientific article published in June 2002

T-cell help dependence of memory CD8+ T-cell expansion upon vaccinia virus challenge relies on CD40 signaling

scientific article published on 24 October 2013

TAP1-independent loading of class I molecules by exogenous viral proteins

scientific article published on 01 June 1995

TIGIT limits immune pathology during viral infections

scientific article published on 09 March 2020

TRANCE, a tumor necrosis factor family member critical for CD40 ligand-independent T helper cell activation

scientific article

TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance

scientific article published on 16 January 2014

Tcf1+ cells are required to maintain the inflationary T cell pool upon MCMV infection

scientific article published on 08 May 2020

Th cells act via two synergistic pathways to promote antiviral CD8+ T cell responses

scientific article published on 29 September 2010

The Janus Face of Follicular T Helper Cells in Chronic Viral Infections.

scientific article

The Salivary Gland Acts as a Sink for Tissue-Resident Memory CD8(+) T Cells, Facilitating Protection from Local Cytomegalovirus Infection

scientific article published on 27 October 2015

The dynamics of mouse cytomegalovirus-specific CD4 T cell responses during acute and latent infection

scientific article

The influence of the phylogenetic inference pipeline on murine antibody repertoire sequencing data following viral infection

The orientation of HIV-1 gp120 binding to the CD4 receptor differentially modulates CD4+ T cell activation

scientific article

The risks of targeting co-inhibitory pathways to modulate pathogen-directed T cell responses ⬇️

scientific article published on January 16, 2013

The role of somatic mutation in the generation of the protective humoral immune response against vesicular stomatitis virus.

scientific article published in December 1996

The transcription factor Rfx7 limits metabolism of NK cells and promotes their maintenance and immunity

scientific article published on 02 July 2018

Tissue maintenance of CMV-specific inflationary memory T cells by IL-15.

scientific article published on 13 April 2018

Tissue-resident memory T cells in cytomegalovirus infection

scientific article published on 5 February 2016

Tracing Antibody Repertoire Evolution by Systems Phylogeny

scholarly article by Alexander Dimitri Yermanos et al published 2 October 2018 in Frontiers in Immunology

Tumor-necrosis factor impairs CD4(+) T cell-mediated immunological control in chronic viral infection

scientific article

Two sequential layers of antibody-mediated control of Legionella pneumophila infection

scientific article published on 18 June 2019

Type I IFN Substitutes for T Cell Help during Viral Infections ⬇️

scientific article published on December 15, 2010

Type I interferons protect T cells against NK cell attack mediated by the activating receptor NCR1.

scientific article published on 5 June 2014

Type-I IFN drives the differentiation of short-lived effector CD8+ T cells in vivo.

scientific article published on 20 December 2011

T‐cell help permits memory CD8+ T‐cell inflation during cytomegalovirus latency ⬇️

scientific article published on July 4, 2011

T‐cell heterogeneity, progenitor–progeny relationships, and function during latent and chronic viral infections

VSV-GP: a potent viral vaccine vector that boosts the immune response upon repeated applications.

scientific article published on 19 February 2014

Variable fate of virus-specific CD4(+) T cells during primary HIV-1 infection

scientific article published on December 1, 2001

Viral nucleoprotein antibodies activate TRIM21 and induce T cell immunity

scientific article published on 01 December 2020

Virological and immunological effects of short-course antiretroviral therapy in primary HIV infection

scientific article published in October 2002

Virus neutralization by germ-line vs. hypermutated antibodies

scientific article published on August 2000

Virus-specific CD8 T cells: activation, differentiation and memory formation

scientific article published on May 2009

Virus-specific major MHC class II-restricted TCR-transgenic mice: effects on humoral and cellular immune responses after viral infection ⬇️

scientific article published on January 1, 1998

‘Stem-like’ precursors are the fount to sustain persistent CD8+ T cell responses

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