List of works - Sumalee Kamchonwongpaisan

2-Phenylnaphthalenes and a polyoxygenated cyclohexene from the stem and root extracts of Uvaria cherrevensis (Annonaceae).

scientific article

A genetically hard-wired metabolic transcriptome in Plasmodium falciparum fails to mount protective responses to lethal antifolates

scientific article

Antimalarial Oxoprotoberberine Alkaloids from the Leaves of Miliusa cuneata.

scientific article published on March 2016

Antimalarial alkaloids from a Bhutanese traditional medicinal plant Corydalis dubia

scientific article

Antiplasmodial activity of atisinium chloride from the Bhutanese medicinal plant, Aconitum orochryseum.

scientific article published on 2 June 2010

Antiplasmodial agents from the Bhutanese medicinal plant Corydalis calliantha. ⬇️

scientific article published in April 2010

Artemisinin effectiveness in erythrocytes is reduced by heme and heme-containing proteins

scientific article

Carbonic anhydrase inhibitors. Inhibition of Plasmodium falciparum carbonic anhydrase with aromatic sulfonamides: towards antimalarials with a novel mechanism of action?

scientific article published in January 2005

Characterization of human malaria parasite Plasmodium falciparum eIF4E homologue and mRNA 5' cap status

scientific article (publication date: October 2007)

Characterization, crystallization and preliminary X-ray analysis of bifunctional dihydrofolate reductase-thymidylate synthase from Plasmodium falciparum

scientific article published on 23 March 2004

Combined Spatial Limitation around Residues 16 and 108 of Plasmodium falciparum Dihydrofolate Reductase Explains Resistance to Cycloguanil

scientific article

Comparative proteomic profiles and the potential markers between Burkholderia pseudomallei and Burkholderia thailandensis

scientific article

Current treatment and drug discovery against Leishmania spp. and Plasmodium spp.: a review

scientific article published on March 2009

Cytochrome c and c1 heme lyases are essential in Plasmodium berghei

article

Cytotoxic and Antimalarial Alkaloids from the Twigs of Dasymaschalon obtusipetalum.

scientific article

DNA hybridization enhancement using piezoelectric microagitation through a liquid coupling medium ⬇️

scientific article published on February 2, 2011

Design, synthesis and biological evaluation of 6-aryl-1,6-dihydro-1,3,5-triazine-2,4-diamines as antiplasmodial antifolates

scientific article published in August 2016

Development of 2,4-diaminopyrimidines as antimalarials based on inhibition of the S108N and C59R+S108N mutants of dihydrofolate reductase from pyrimethamine-resistant Plasmodium falciparum

scientific article published in March 2002

Effect of N-terminal truncation of Plasmodium falciparum dihydrofolate reductase on dihydrofolate reductase and thymidylate synthase activity.

scientific article

Enhancement of DNA hybridization under acoustic streaming with three-piezoelectric-transducer system ⬇️

scientific article published on November 10, 2011

Estimating mRNA lengths from Plasmodium falciparum genes by Virtual Northern RNA-seq analysis.

scientific article published on 5 November 2015

Evaluation of an ethnopharmacologically selected Bhutanese medicinal plants for their major classes of phytochemicals and biological activities.

scientific article published on 28 June 2011

Evaluation of antimycobacterial, antiplasmodial and cytotoxic activities of preussomerins isolated from the lichenicolous fungus Microsphaeropsis sp. BCC 3050.

scientific article published on January 2002

Evaluation of the activities of pyrimethamine analogs against Plasmodium vivax and Plasmodium falciparum dihydrofolate reductase-thymidylate synthase using in vitro enzyme inhibition and bacterial complementation assays.

scientific article

Exploiting Structural Analysis, in Silico Screening, and Serendipity To Identify Novel Inhibitors of Drug-Resistant Falciparum Malaria

scientific article

Flow cytometric enumeration of Plasmodium berghei-infected red blood cells stained with SYBR Green I.

scientific article published on 29 December 2011

Folate metabolism as a source of molecular targets for antimalarials.

scientific article published on June 2006

GC/GC-MS analysis, isolation and identification of bioactive essential oil components from the Bhutanese medicinal plant, Pleurospermum amabile

scientific article published on September 2013

Global gene expression profiling of Plasmodium falciparum in response to the anti-malarial drug pyronaridine ⬇️

scientific article published on August 18, 2011

Hematological parameters and red blood cell morphological abnormality of Glucose-6-Phosphate dehydrogenase deficiency co-inherited with thalassemia

scientific article published on 15 June 2017

Identifying antimalarial compounds targeting dihydrofolate reductase-thymidylate synthase (DHFR-TS) by chemogenomic profiling

scientific article published on 2 May 2016

Immobilization of malarial (Plasmodium falciparum) dihydrofolate reductase for the selection of tight-binding inhibitors from combinatorial library.

scientific article

Inducible knockdown of Plasmodium gene expression using the glmS ribozyme

scientific article (publication date: 2013)

Inhibition of Glutathione Biosynthesis Sensitizes Plasmodium berghei to Antifolates

scientific article published on 7 March 2016

Inhibitors of multiple mutants of Plasmodium falciparum dihydrofolate reductase and their antimalarial activities.

scientific article published on January 2004

Inhibitory effect of novel iron chelator, 1-(N-acetyl-6-aminohexyl)-3-hydroxy-2-methylpyridin-4-one (CM1) and green tea extract on growth of Plasmodium falciparum

scientific article

Insights into antifolate resistance from malarial DHFR-TS structures

scientific article (publication date: May 2003)

Interactions between cycloguanil derivatives and wild type and resistance-associated mutant Plasmodium falciparum dihydrofolate reductases

scientific article published on 21 January 2009

Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target

scientific article

Molecular characterization of Plasmodium falciparum Bruno/CELF RNA binding proteins

scientific article (publication date: November 2014)

Molecular dynamics of interactions between rigid and flexible antifolates and dihydrofolate reductase from pyrimethamine-sensitive and pyrimethamine-resistant Plasmodium falciparum.

scientific article published on 4 June 2014

Monitoring drug resistance in Plasmodium falciparum clinical isolates collected from Northern Thailand

scientific article

Mutational analysis of Plasmodium falciparum dihydrofolate reductase: the role of aspartate 54 and phenylalanine 223 on catalytic activity and antifolate binding.

scientific article published in May 2002

Origin of robustness in generating drug-resistant malaria parasites

scientific article

Phytochemical and Biological Activity Studies of the Bhutanese Medicinal Plant Corydalis crispa

article

Phytochemical and biological activity studies of the Bhutanese medicinal plant Corydalis crispa

scientific article published on May 1, 2012

Plasmodium parasites mount an arrest response to dihydroartemisinin, as revealed by whole transcriptome shotgun sequencing (RNA-seq) and microarray study

scientific article

Preclinical Evaluation of the Antifolate QN254, 5-Chloro- N'6'-(2,5-Dimethoxy-Benzyl)-Quinazoline-2,4,6-Triamine, as an Antimalarial Drug Candidate

scientific article

Selection of drug resistant mutants from random library of Plasmodium falciparum dihydrofolate reductase in Plasmodium berghei model ⬇️

scientific article

Small-scale in vitro culture and purification of Plasmodium berghei for transfection experiment.

scientific article published in February 2011

Stepwise acquisition of pyrimethamine resistance in the malaria parasite

scientific article published on 08 July 2009

Stoichiometric selection of tight-binding inhibitors by wild-type and mutant forms of malarial (Plasmodium falciparum) dihydrofolate reductase.

scientific article published in March 2005

Synthesis of solution-phase combinatorial library of 4,6-diamino-1,2-dihydro-1,3,5-triazine and identification of new leads against A16V+S108T mutant dihydrofolate reductase of Plasmodium falciparum.

scientific article

Target guided synthesis of 5-benzyl-2,4-diamonopyrimidines: their antimalarial activities and binding affinities to wild type and mutant dihydrofolate reductases from Plasmodium falciparum

scientific article (publication date: 15 January 2004)

The role of tryptophan-48 in catalysis and binding of inhibitors of Plasmodium falciparum dihydrofolate reductase.

scientific article published on 14 January 2007

Transgenic Plasmodium parasites stably expressing Plasmodium vivax dihydrofolate reductase-thymidylate synthase as in vitro and in vivo models for antifolate screening

scientific article

Trypanosomal Dihydrofolate Reductase Reveals Natural Antifolate Resistance ⬇️

scientific article published on June 16, 2011

Use of bacterial surrogates as a tool to explore antimalarial drug interaction: Synergism between inhibitors of malarial dihydrofolate reductase and dihydropteroate synthase.

scientific article published on 18 May 2015

Validation of deoxyhypusine synthase as an antimalarial target

scientific article published in 2019

List of works by Sumalee Kamchonwongpaisan

2-Phenylnaphthalenes and a polyoxygenated cyclohexene from the stem and root extracts of Uvaria cherrevensis (Annonaceae).

A genetically hard-wired metabolic transcriptome in Plasmodium falciparum fails to mount protective responses to lethal antifolates

Antimalarial Oxoprotoberberine Alkaloids from the Leaves of Miliusa cuneata.

Antimalarial alkaloids from a Bhutanese traditional medicinal plant Corydalis dubia

Antiplasmodial activity of atisinium chloride from the Bhutanese medicinal plant, Aconitum orochryseum.

Antiplasmodial agents from the Bhutanese medicinal plant Corydalis calliantha. ⬇️

Artemisinin effectiveness in erythrocytes is reduced by heme and heme-containing proteins

Carbonic anhydrase inhibitors. Inhibition of Plasmodium falciparum carbonic anhydrase with aromatic sulfonamides: towards antimalarials with a novel mechanism of action?

Characterization of human malaria parasite Plasmodium falciparum eIF4E homologue and mRNA 5' cap status

Characterization, crystallization and preliminary X-ray analysis of bifunctional dihydrofolate reductase-thymidylate synthase from Plasmodium falciparum

Combined Spatial Limitation around Residues 16 and 108 of Plasmodium falciparum Dihydrofolate Reductase Explains Resistance to Cycloguanil

Comparative proteomic profiles and the potential markers between Burkholderia pseudomallei and Burkholderia thailandensis

Current treatment and drug discovery against Leishmania spp. and Plasmodium spp.: a review

Cytochrome c and c1 heme lyases are essential in Plasmodium berghei

Cytotoxic and Antimalarial Alkaloids from the Twigs of Dasymaschalon obtusipetalum.

DNA hybridization enhancement using piezoelectric microagitation through a liquid coupling medium ⬇️

Design, synthesis and biological evaluation of 6-aryl-1,6-dihydro-1,3,5-triazine-2,4-diamines as antiplasmodial antifolates

Development of 2,4-diaminopyrimidines as antimalarials based on inhibition of the S108N and C59R+S108N mutants of dihydrofolate reductase from pyrimethamine-resistant Plasmodium falciparum

Effect of N-terminal truncation of Plasmodium falciparum dihydrofolate reductase on dihydrofolate reductase and thymidylate synthase activity.

Enhancement of DNA hybridization under acoustic streaming with three-piezoelectric-transducer system ⬇️

Estimating mRNA lengths from Plasmodium falciparum genes by Virtual Northern RNA-seq analysis.

Evaluation of an ethnopharmacologically selected Bhutanese medicinal plants for their major classes of phytochemicals and biological activities.

Evaluation of antimycobacterial, antiplasmodial and cytotoxic activities of preussomerins isolated from the lichenicolous fungus Microsphaeropsis sp. BCC 3050.

Evaluation of the activities of pyrimethamine analogs against Plasmodium vivax and Plasmodium falciparum dihydrofolate reductase-thymidylate synthase using in vitro enzyme inhibition and bacterial complementation assays.

Exploiting Structural Analysis, in Silico Screening, and Serendipity To Identify Novel Inhibitors of Drug-Resistant Falciparum Malaria

Flow cytometric enumeration of Plasmodium berghei-infected red blood cells stained with SYBR Green I.

Folate metabolism as a source of molecular targets for antimalarials.

GC/GC-MS analysis, isolation and identification of bioactive essential oil components from the Bhutanese medicinal plant, Pleurospermum amabile

Global gene expression profiling of Plasmodium falciparum in response to the anti-malarial drug pyronaridine ⬇️

Hematological parameters and red blood cell morphological abnormality of Glucose-6-Phosphate dehydrogenase deficiency co-inherited with thalassemia

Identifying antimalarial compounds targeting dihydrofolate reductase-thymidylate synthase (DHFR-TS) by chemogenomic profiling

Immobilization of malarial (Plasmodium falciparum) dihydrofolate reductase for the selection of tight-binding inhibitors from combinatorial library.

Inducible knockdown of Plasmodium gene expression using the glmS ribozyme

Inhibition of Glutathione Biosynthesis Sensitizes Plasmodium berghei to Antifolates

Inhibitors of multiple mutants of Plasmodium falciparum dihydrofolate reductase and their antimalarial activities.

Inhibitory effect of novel iron chelator, 1-(N-acetyl-6-aminohexyl)-3-hydroxy-2-methylpyridin-4-one (CM1) and green tea extract on growth of Plasmodium falciparum

Insights into antifolate resistance from malarial DHFR-TS structures

Interactions between cycloguanil derivatives and wild type and resistance-associated mutant Plasmodium falciparum dihydrofolate reductases

Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target

Molecular characterization of Plasmodium falciparum Bruno/CELF RNA binding proteins

Molecular dynamics of interactions between rigid and flexible antifolates and dihydrofolate reductase from pyrimethamine-sensitive and pyrimethamine-resistant Plasmodium falciparum.

Monitoring drug resistance in Plasmodium falciparum clinical isolates collected from Northern Thailand

Mutational analysis of Plasmodium falciparum dihydrofolate reductase: the role of aspartate 54 and phenylalanine 223 on catalytic activity and antifolate binding.

Origin of robustness in generating drug-resistant malaria parasites

Phytochemical and Biological Activity Studies of the Bhutanese Medicinal Plant Corydalis crispa

Phytochemical and biological activity studies of the Bhutanese medicinal plant Corydalis crispa

Plasmodium parasites mount an arrest response to dihydroartemisinin, as revealed by whole transcriptome shotgun sequencing (RNA-seq) and microarray study

Preclinical Evaluation of the Antifolate QN254, 5-Chloro- N'6'-(2,5-Dimethoxy-Benzyl)-Quinazoline-2,4,6-Triamine, as an Antimalarial Drug Candidate

Selection of drug resistant mutants from random library of Plasmodium falciparum dihydrofolate reductase in Plasmodium berghei model ⬇️

Small-scale in vitro culture and purification of Plasmodium berghei for transfection experiment.

Stepwise acquisition of pyrimethamine resistance in the malaria parasite

Stoichiometric selection of tight-binding inhibitors by wild-type and mutant forms of malarial (Plasmodium falciparum) dihydrofolate reductase.

Synthesis of solution-phase combinatorial library of 4,6-diamino-1,2-dihydro-1,3,5-triazine and identification of new leads against A16V+S108T mutant dihydrofolate reductase of Plasmodium falciparum.

Target guided synthesis of 5-benzyl-2,4-diamonopyrimidines: their antimalarial activities and binding affinities to wild type and mutant dihydrofolate reductases from Plasmodium falciparum

The role of tryptophan-48 in catalysis and binding of inhibitors of Plasmodium falciparum dihydrofolate reductase.

Transgenic Plasmodium parasites stably expressing Plasmodium vivax dihydrofolate reductase-thymidylate synthase as in vitro and in vivo models for antifolate screening

Trypanosomal Dihydrofolate Reductase Reveals Natural Antifolate Resistance ⬇️

Use of bacterial surrogates as a tool to explore antimalarial drug interaction: Synergism between inhibitors of malarial dihydrofolate reductase and dihydropteroate synthase.

Validation of deoxyhypusine synthase as an antimalarial target