List of works - Paul A Goepfert

A phase I trial of preventive HIV vaccination with heterologous poxviral-vectors containing matching HIV-1 inserts in healthy HIV-uninfected subjects

scientific article

A phase IIA randomized clinical trial of a multiclade HIV-1 DNA prime followed by a multiclade rAd5 HIV-1 vaccine boost in healthy adults (HVTN204)

scientific article (publication date: 2011)

Antigenic competition in CD4+ T cell responses in a randomized, multicenter, double-blind clinical HIV vaccine trial

scientific article published on 01 November 2019

CD151 Expression Is Associated with a Hyperproliferative T Cell Phenotype

scientific article published on 27 September 2017

CD8 T cell response and evolutionary pressure to HIV-1 cryptic epitopes derived from antisense transcription

scientific article

CD8 T cells targeting adapted epitopes in chronic HIV infection promote dendritic cell maturation and CD4 T cell trans-infection

scientific article published on 09 August 2019

Comparative Evaluation of HIV-1 Neutralization in External Secretions and Sera of HIV-1-Infected Women ⬇️

scientific article published on December 28, 2012

Compensatory mutation partially restores fitness and delays reversion of escape mutation within the immunodominant HLA-B*5703-restricted Gag epitope in chronic human immunodeficiency virus type 1 infection

scientific article

Elucidation of hepatitis C virus transmission and early diversification by single genome sequencing

scientific article

Escape and compensation from early HLA-B57-mediated cytotoxic T-lymphocyte pressure on human immunodeficiency virus type 1 Gag alter capsid interactions with cyclophilin A.

scientific article

Evolution of HLA-B5703 HIV-1 escape mutations in HLA-B5703-positive individuals and their transmission recipients

scientific article published on 23 March 2009

HIV-1-Specific CD8 T Cells Exhibit Limited Cross-Reactivity during Acute Infection.

scientific article published on 16 March 2016

Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection

scientific article (publication date: 27 May 2008)

Identification of an ER retrieval signal in a retroviral glycoprotein ⬇️

scientific article published on August 25, 1995

Identification, molecular cloning, and analysis of full-length hepatitis C virus transmitted/founder genotypes 1, 3, and 4

scientific article

Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated

scientific article

MRKAd5 HIV-1 Gag/Pol/Nef vaccine-induced T-cell responses inadequately predict distance of breakthrough HIV-1 sequences to the vaccine or viral load

scientific article

Mechanistic inferences from clinical reports of SARS-CoV-2

scientific article published on 27 May 2020

Modeling sequence evolution in acute HIV-1 infection

scientific article published on 04 August 2009

Mutually exclusive T-cell receptor induction and differential susceptibility to human immunodeficiency virus type 1 mutational escape associated with a two-amino-acid difference between HLA class I subtypes

scientific article published on 22 November 2006

Phase I/II randomized trial of safety and immunogenicity of LIPO-5 alone, ALVAC-HIV (vCP1452) alone, and ALVAC-HIV (vCP1452) prime/LIPO-5 boost in healthy, HIV-1-uninfected adult participants

scientific article

Polyclonal B cell differentiation and loss of gastrointestinal tract germinal centers in the earliest stages of HIV-1 infection

scientific article

Recurrent signature patterns in HIV-1 B clade envelope glycoproteins associated with either early or chronic infections

scientific article

Safety and Immunogenicity of an HIV Adenoviral Vector Boost after DNA Plasmid Vaccine Prime by Route of Administration: A Randomized Clinical Trial ⬇️

scientific article published on September 12, 2011

Safety and immunogenicity of a high-titered canarypox vaccine in combination with rgp120 in a diverse population of HIV-1-uninfected adults: AIDS Vaccine Evaluation Group Protocol 022A.

scientific article

T cell responses in HIV type 1-infected adolescent minorities share similar epitope specificities with whites despite significant differences in HLA class I alleles

scientific article published in November 2003

TOX is expressed by exhausted and polyfunctional human effector memory CD8+ T cells

scientific article published on 01 July 2020

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation

scientific article

Transmitted virus fitness and host T cell responses collectively define divergent infection outcomes in two HIV-1 recipients

scientific article

Understanding the CD8 T-cell response in natural HIV control

article

List of works by Paul A Goepfert

A phase I trial of preventive HIV vaccination with heterologous poxviral-vectors containing matching HIV-1 inserts in healthy HIV-uninfected subjects

A phase IIA randomized clinical trial of a multiclade HIV-1 DNA prime followed by a multiclade rAd5 HIV-1 vaccine boost in healthy adults (HVTN204)

Antigenic competition in CD4+ T cell responses in a randomized, multicenter, double-blind clinical HIV vaccine trial

CD151 Expression Is Associated with a Hyperproliferative T Cell Phenotype

CD8 T cell response and evolutionary pressure to HIV-1 cryptic epitopes derived from antisense transcription

CD8 T cells targeting adapted epitopes in chronic HIV infection promote dendritic cell maturation and CD4 T cell trans-infection

Comparative Evaluation of HIV-1 Neutralization in External Secretions and Sera of HIV-1-Infected Women ⬇️

Compensatory mutation partially restores fitness and delays reversion of escape mutation within the immunodominant HLA-B*5703-restricted Gag epitope in chronic human immunodeficiency virus type 1 infection

Elucidation of hepatitis C virus transmission and early diversification by single genome sequencing

Escape and compensation from early HLA-B57-mediated cytotoxic T-lymphocyte pressure on human immunodeficiency virus type 1 Gag alter capsid interactions with cyclophilin A.

Evolution of HLA-B*5703 HIV-1 escape mutations in HLA-B*5703-positive individuals and their transmission recipients

HIV-1-Specific CD8 T Cells Exhibit Limited Cross-Reactivity during Acute Infection.

Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection

Identification of an ER retrieval signal in a retroviral glycoprotein ⬇️

Identification, molecular cloning, and analysis of full-length hepatitis C virus transmitted/founder genotypes 1, 3, and 4

Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated

MRKAd5 HIV-1 Gag/Pol/Nef vaccine-induced T-cell responses inadequately predict distance of breakthrough HIV-1 sequences to the vaccine or viral load

Mechanistic inferences from clinical reports of SARS-CoV-2

Modeling sequence evolution in acute HIV-1 infection

Mutually exclusive T-cell receptor induction and differential susceptibility to human immunodeficiency virus type 1 mutational escape associated with a two-amino-acid difference between HLA class I subtypes

Phase I/II randomized trial of safety and immunogenicity of LIPO-5 alone, ALVAC-HIV (vCP1452) alone, and ALVAC-HIV (vCP1452) prime/LIPO-5 boost in healthy, HIV-1-uninfected adult participants

Polyclonal B cell differentiation and loss of gastrointestinal tract germinal centers in the earliest stages of HIV-1 infection

Recurrent signature patterns in HIV-1 B clade envelope glycoproteins associated with either early or chronic infections

Safety and Immunogenicity of an HIV Adenoviral Vector Boost after DNA Plasmid Vaccine Prime by Route of Administration: A Randomized Clinical Trial ⬇️

Safety and immunogenicity of a high-titered canarypox vaccine in combination with rgp120 in a diverse population of HIV-1-uninfected adults: AIDS Vaccine Evaluation Group Protocol 022A.

T cell responses in HIV type 1-infected adolescent minorities share similar epitope specificities with whites despite significant differences in HLA class I alleles

TOX is expressed by exhausted and polyfunctional human effector memory CD8+ T cells

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation

Transmitted virus fitness and host T cell responses collectively define divergent infection outcomes in two HIV-1 recipients

Understanding the CD8 T-cell response in natural HIV control

Evolution of HLA-B5703 HIV-1 escape mutations in HLA-B5703-positive individuals and their transmission recipients