List of works - Tao Lu

Activation of cAMP-responsive-element-binding protein by PI3 kinase and p38 MAPK is essential for elevated expression of transforming growth factor β2 in cancer cells

scientific article

Adapting AlphaLISA high throughput screen to discover a novel small-molecule inhibitor targeting protein arginine methyltransferase 5 in pancreatic and colorectal cancers.

scientific article published on 23 May 2017

Aging: Cancer - an unlikely couple

scientific article published on 20 September 2017

CDK8/19 Mediator kinases potentiate induction of transcription by NFκB.

scientific article published on 30 August 2017

Critical role of NF-κB in pancreatic cancer

scientific article

Critical role of phosphorylation of serine 165 of YBX1 on the activation of NF-κB in colon cancer

scientific article published on 08 August 2015

Cytokine overexpression and constitutive NFkappaB in cancer

scientific article published on 4 September 2004

Development of an AlphaLISA high throughput technique to screen for small molecule inhibitors targeting protein arginine methyltransferases.

scientific article

Dose-dependent cross-talk between the transforming growth factor-beta and interleukin-1 signaling pathways

scholarly article

Genetic pathways, prevention, and treatment of sporadic colorectal cancer

scientific article

Lysine methylation of promoter-bound transcription factors and relevance to cancer ⬇️

scientific article published on December 14, 2010

Modulating the modulators: regulation of protein arginine methyltransferases by post-translational modifications

scientific article published on 03 July 2020

Mutagenesis by reversible promoter insertion to study the activation of NF-kappaB.

scientific article

NF-κB: Regulation by Methylation

scientific article published on 03 September 2015

Novel Serine 176 Phosphorylation of YBX1 Activates NF-κB in Colon Cancer.

scientific article

PHF20 regulates NF-κB signalling by disrupting recruitment of PP2A to p65

scientific article published on January 2013

PRMT5 dimethylates R30 of the p65 subunit to activate NF-κB.

scientific article published on 31 July 2013

PRMTs and miRNAs: functional cooperation in cancer and beyond

scientific article published on 24 June 2019

Participation of the conventional calpains in apoptosis

scientific article

Phosphorylation of the Regulators, a Complex Facet of NF-κB Signaling in Cancer

scientific article published on 26 December 2020

Protein arginine methylation of non-histone proteins and its role in diseases

scientific article published on 02 December 2013

Regulation of NF-kappaB by NSD1/FBXL11-dependent reversible lysine methylation of p65.

scientific article

Regulation of a PRMT5/NF-κB Axis by Phosphorylation of PRMT5 at Serine 15 in Colorectal Cancer ⬇️

scientific article published on 23 May 2020

Reversible methylation of promoter-bound STAT3 by histone-modifying enzymes ⬇️

scientific article published on November 23, 2010

Role of ChIP-seq in the discovery of transcription factor binding sites, differential gene regulation mechanism, epigenetic marks and beyond.

scientific article published on January 2014

Role of Novel Serine 316 Phosphorylation of the p65 Subunit of NF-κB in Differential Gene Regulation.

scientific article

Role of lysine methylation of NF-κB in differential gene regulation

scientific article

Role of post-translational modification of the Y box binding protein 1 in human cancers

scientific article published on 27 May 2015

Secreted transforming growth factor beta2 activates NF-kappaB, blocks apoptosis, and is essential for the survival of some tumor cells

scientific article

Secretion of cytokines and growth factors as a general cause of constitutive NFkappaB activation in cancer

scientific article published on March 2004

Targeting microenvironment in cancer therapeutics

scientific article

Transposon-based mutagenesis identifies short RIP1 as an activator of NFkappaB.

scientific article

Use of forward genetics to discover novel regulators of NF-kappaB.

scientific article published on 23 December 2009

Using sequential immunoprecipitation and mass spectrometry to identify methylation of NF-κB.

scientific article

Validation-based insertional mutagenesis identifies lysine demethylase FBXL11 as a negative regulator of NFkappaB.

scientific article published on September 2009

List of works by Tao Lu

Activation of cAMP-responsive-element-binding protein by PI3 kinase and p38 MAPK is essential for elevated expression of transforming growth factor β2 in cancer cells

Adapting AlphaLISA high throughput screen to discover a novel small-molecule inhibitor targeting protein arginine methyltransferase 5 in pancreatic and colorectal cancers.

Aging: Cancer - an unlikely couple

CDK8/19 Mediator kinases potentiate induction of transcription by NFκB.

Critical role of NF-κB in pancreatic cancer

Critical role of phosphorylation of serine 165 of YBX1 on the activation of NF-κB in colon cancer

Cytokine overexpression and constitutive NFkappaB in cancer

Development of an AlphaLISA high throughput technique to screen for small molecule inhibitors targeting protein arginine methyltransferases.

Dose-dependent cross-talk between the transforming growth factor-beta and interleukin-1 signaling pathways

Genetic pathways, prevention, and treatment of sporadic colorectal cancer

Lysine methylation of promoter-bound transcription factors and relevance to cancer ⬇️

Modulating the modulators: regulation of protein arginine methyltransferases by post-translational modifications

Mutagenesis by reversible promoter insertion to study the activation of NF-kappaB.

NF-κB: Regulation by Methylation

Novel Serine 176 Phosphorylation of YBX1 Activates NF-κB in Colon Cancer.

PHF20 regulates NF-κB signalling by disrupting recruitment of PP2A to p65

PRMT5 dimethylates R30 of the p65 subunit to activate NF-κB.

PRMTs and miRNAs: functional cooperation in cancer and beyond

Participation of the conventional calpains in apoptosis

Phosphorylation of the Regulators, a Complex Facet of NF-κB Signaling in Cancer

Protein arginine methylation of non-histone proteins and its role in diseases

Regulation of NF-kappaB by NSD1/FBXL11-dependent reversible lysine methylation of p65.

Regulation of a PRMT5/NF-κB Axis by Phosphorylation of PRMT5 at Serine 15 in Colorectal Cancer ⬇️

Reversible methylation of promoter-bound STAT3 by histone-modifying enzymes ⬇️

Role of ChIP-seq in the discovery of transcription factor binding sites, differential gene regulation mechanism, epigenetic marks and beyond.

Role of Novel Serine 316 Phosphorylation of the p65 Subunit of NF-κB in Differential Gene Regulation.

Role of lysine methylation of NF-κB in differential gene regulation

Role of post-translational modification of the Y box binding protein 1 in human cancers

Secreted transforming growth factor beta2 activates NF-kappaB, blocks apoptosis, and is essential for the survival of some tumor cells

Secretion of cytokines and growth factors as a general cause of constitutive NFkappaB activation in cancer

Targeting microenvironment in cancer therapeutics

Transposon-based mutagenesis identifies short RIP1 as an activator of NFkappaB.

Use of forward genetics to discover novel regulators of NF-kappaB.

Using sequential immunoprecipitation and mass spectrometry to identify methylation of NF-κB.

Validation-based insertional mutagenesis identifies lysine demethylase FBXL11 as a negative regulator of NFkappaB.