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List of works by Klaus-Dieter Wernecke

A comparison of three scores to screen for delirium on the surgical ward.

scientific article published in March 2010

A prospective, randomized, double-blind, multicenter study comparing remifentanil with fentanyl in mechanically ventilated patients

scientific article

Activity of clotting factors in fresh-frozen plasma during storage at 4 degrees C over 6 days

scientific article published on 21 January 2009

Adjustment to chronic pain in back pain patients classified according to the motivational stages of chronic pain management

scientific article published in June 2006

Adjuvant chemotherapy with folinic acid and 5-fluorouracil in patients with locally advanced rectal cancer previously treated by preoperative radiochemotherapy and curative tumor resection

scientific article published on 14 January 2006

Altered cell-mediated immunity and increased postoperative infection rate in long-term alcoholic patients

scientific article published in May 2004

Apheresis therapies for NMOSD attacks: A retrospective study of 207 therapeutic interventions

Apical tissue tracking echocardiography for characterization of regional left ventricular function: comparison with magnetic resonance imaging in patients after myocardial infarction

scientific article published in March 2003

Arterial and cardiac disease in young adults with childhood-onset end-stage renal disease-impact of calcium and vitamin D therapy

scientific article published on 22 March 2006

Assessment of agreement and trending between haemodynamic monitors is still challenging

scientific article published on 25 March 2014

Association of comorbidities with postoperative in-hospital mortality: a retrospective cohort study

scientific article

Association of retinal and macular damage with brain atrophy in multiple sclerosis

scientific article published in 2011

Attention Network Test reveals alerting network dysfunction in multiple sclerosis

scientific article published on 7 December 2009

Attitudes toward mode of hysterectomy: a survey-based study among German gynecologists

scientific article published on July 4, 2012

Balanced 10% hydroxyethyl starch compared with balanced 6% hydroxyethyl starch and balanced crystalloid using a goal-directed hemodynamic algorithm in pancreatic surgery: A randomized clinical trial

scientific article published in April 2018

Black cohosh and St. John's wort for climacteric complaints: a randomized trial

scientific article published in February 2006

CD31+ naïve Th cells are stable during six months following kidney transplantation: implications for post-transplant thymic function

scientific article published in July 2005

Catecholamine dosing and survival in adult intensive care unit patients

scientific article published in April 2013

Central Venous-Arterial pCO2 Difference Identifies Microcirculatory Hypoperfusion in Cardiac Surgical Patients With Normal Central Venous Oxygen Saturation: A Retrospective Analysis

scientific article published on 6 January 2015

Circulating MACC1 Transcripts in Colorectal Cancer Patient Plasma Predict Metastasis and Prognosis

scientific article published on November 14, 2012

Circulating Metastasis Associated in Colon Cancer 1 transcripts in gastric cancer patient plasma as diagnostic and prognostic biomarker

scientific article

Clonidine attenuated early proinflammatory response in T-cell subsets after cardiac surgery

scientific article published in October 2006

Clotting factor activity in thawed Octaplas® LG during storage at 2-6°C for 6 days from a quality assurance point of view

scientific article published on 26 February 2012

Correction: Perioperative Care and the Importance of Continuous Quality Improvement-A Controlled Intervention Study in Three Tanzanian Hospitals

scientific article published on 19 May 2016

Critical illness myopathy is frequent: accompanying neuropathy protracts ICU discharge

scientific article published on 27 August 2010

Decreased proopiomelanocortin mRNA in lymphocytes of chronic alcoholics after intravenous human corticotropin releasing factor injection

scientific article published in November 2003

Depression and essential health risk factors in surgical patients in the preoperative anaesthesiological assessment clinic

scientific article

Diagnostic and Prognostic Value of Metastasis Inducer S100A4 Transcripts in Plasma of Colon, Rectal, and Gastric Cancer Patients

scientific article published on March 1, 2011

Diagnostic value of plasma NGAL and intraoperative diuresis for AKI after major gynecological surgery in patients treated within an intraoperative goal-directed hemodynamic algorithm: A substudy of a randomized controlled trial

scientific article published on July 2017

Different assessment tools for intensive care unit delirium: which score to use?

scientific article published in February 2010

Disease Modification in Multiple Sclerosis by Flupirtine-Results of a Randomized Placebo Controlled Phase II Trial

Does the severity of preoperative anemia or blood transfusion have a stronger impact on long-term survival after cardiac surgery?

scientific article published on 22 June 2016

Duration of fluid fasting and choice of analgesic are modifiable factors for early postoperative delirium

scientific article published in May 2010

Dysfunction of alveolar macrophages after cardiac surgery and postoperative pneumonia?--An observational study

scientific article

Early administration of levosimendan is associated with improved kidney function after cardiac surgery - a retrospective analysis.

scientific article

Early deep sedation is associated with decreased in-hospital and two-year follow-up survival

scientific article published on 28 April 2015

Early levosimendan administration is associated with decreased mortality after cardiac surgery

scientific article published on 13 March 2015

Effect of blood-sugar limitation on intensive care mortality: Intragroup evaluation

scientific article

Effects of Polymorphisms in CYP2D6, CYP2C9, and CYP2C19 on Trimipramine Pharmacokinetics

scientific article published on October 1, 2003

Effects of an Innovative Psychotherapy Program for Surgical Patients: Bridging Intervention in Anesthesiology--A Randomized Controlled Trial

scientific article published on 25 April 2015

Effects of repetitive imagination of alcohol consumption on craving in alcohol-dependent patients: A pilot study

scientific article published on 7 August 2016

End-of-life decisions in intensive care medicine-shared decision-making and intensive care unit length of stay.

scientific article published in March 2015

End-of-life decisions in surgical intensive care medicine - the relevance of blood transfusions

scientific article published on 24 March 2016

Ethanol changes gene expression of transcription factors and cytokine production of CD4+ T-cell subsets in PBMCs stimulated with LPS.

scientific article published on 8 December 2010

Evaluation of the prognostic significance of androgen receptor expression in metastatic breast cancer

scientific article published on 21 April 2006

Fears and Concerns of Patients with Uterine Fibroids - a Survey of 807 Women

scientific article published on 25 September 2017

Forensic age estimation in living subjects: the ethnic factor in wisdom tooth mineralization

scientific article published on 6 February 2004

Four-phase rhinomanometry: a multicentric retrospective analysis of 36,563 clinical measurements.

scientific article

Functional impairment prior to major non-cardiac surgery is associated with mortality within one year in elderly patients with gastrointestinal, gynaecological and urogenital cancer: A prospective observational cohort study

scientific article

Gender-related outcome difference is related to course of sepsis on mixed ICUs: a prospective, observational clinical study

scientific article published on 21 June 2011

Haemodynamic Optimization by Oesophageal Doppler and Pulse Power Wave Analysis in Liver Surgery: A Randomised Controlled Trial

scientific article published on 17 July 2015

Hazardous alcohol consumption and sense of coherence in emergency department patients with minor trauma

scientific article published on 10 October 2005

Health-related quality of life in urban surgical emergency department patients: comparison with a representative German population sample

scientific article

Hemodynamic effects of alpha1-adrenoceptor antagonist, doxazosin, in patients with chronic congestive heart failure

scientific article

High Dose Rate (HDR) Brachytherapy with Conformal Radiation Therapy for Localized Prostate Cancer

scientific article published on 18 January 2005

High central venous saturation after cardiac surgery is associated with increased organ failure and long-term mortality: an observational cross-sectional study

scientific article published on 16 April 2015

High dose rate brachytherapy of localized prostate cancer

scientific article published on 01 April 2002

High-dose baclofen for the treatment of alcohol dependence (BACLAD study): a randomized, placebo-controlled trial

scientific article

How to implement monitoring tools for sedation, pain and delirium in the intensive care unit: an experimental cohort study

scientific article published on 4 September 2012

Hyperfractionated accelerated chemoradiation with concurrent fluorouracil-mitomycin is more effective than dose-escalated hyperfractionated accelerated radiation therapy alone in locally advanced head and neck cancer: final results of the radiothera

scientific article

Hyperfractionated accelerated radiation therapy (HART) of 70.6 Gy with concurrent 5-FU/Mitomycin C is superior to HART of 77.6 Gy alone in locally advanced head and neck cancer: long-term results of the ARO 95-06 randomized phase III trial.

scientific article

Impact of Gender on Three-Month Outcome and Left Ventricular Remodeling After Transfemoral Transcatheter Aortic Valve Implantation

scientific article published on June 2, 2012

Impact of adherence to standard operating procedures for pneumonia on outcome of intensive care unit patients

scientific article published in January 2009

Impact of preoperative 18F-FDG PET/CT on survival of resected mono-metastatic non-small cell lung cancer

scientific article

Impact of retained blood requiring reintervention on outcomes after cardiac surgery

scientific article

In vitro and ex vivo Measurement of Prophylactic Dabigatran Concentrations with a New Ecarin-Based Thromboelastometry Test

scientific article

In vivo application of Granulocyte-Macrophage Colony-stimulating Factor enhances postoperative qualitative monocytic function

scientific article published on 8 April 2017

Independent risk factors for postoperative pain in need of intervention early after awakening from general anaesthesia.

scientific article published on 6 May 2009

Influence of Granulocyte-Macrophage Colony-Stimulating Factor or Influenza Vaccination on HLA-DR, Infection and Delirium Days in Immunosuppressed Surgical Patients: Double Blind, Randomised Controlled Trial.

scientific article published on 7 December 2015

Influence of Volatile Anesthesia on the Release of Glutamate and other Amino Acids in the Nucleus Accumbens in a Rat Model of Alcohol Withdrawal: A Pilot Study

scientific article

Influence of female sex and fertile age on neuromyelitis optica spectrum disorders

scientific article

Influence of goal-directed therapy with balanced crystalloid-colloid or unbalanced crystalloid solution on base excess.

scientific article published on 10 February 2014

Influence of organ at risk definition on rectal dose-volume histograms in patients with prostate cancer undergoing external-beam radiotherapy

scientific article published in May 2006

Influence of preoperative vaccination on monocytic HLA-DR expression and postoperative infection rate of patients with upper aerodigestive tract cancer: A randomised trial

scientific article published in August 2015

Influenza A (H1N1) vs non-H1N1 ARDS: analysis of clinical course

scientific article published on 30 December 2013

Intensive Care Infection Score--A new approach to distinguish between infectious and noninfectious processes in intensive care and medicosurgical patients.

scientific article published on 7 April 2015

Intervention at the level of the neuroendocrine-immune axis and postoperative pneumonia rate in long-term alcoholics

scientific article published on 25 May 2006

Lipid-lowering effect of 2 dosages of a soy protein supplement in hypercholesterolemia

scientific article published in March 2005

Long-term sequelae of acute respiratory distress syndrome caused by severe community-acquired pneumonia: Delirium-associated cognitive impairment and post-traumatic stress disorder

scientific article published in January 2018

Low contrast visual acuity testing is associated with cognitive performance in multiple sclerosis: a cross-sectional pilot study

scientific article

Lower tidal volume strategy (≈3 ml/kg) combined with extracorporeal CO2 removal versus 'conventional' protective ventilation (6 ml/kg) in severe ARDS: the prospective randomized Xtravent-study

scientific article published on 10 January 2013

Major influence of liver function itself but not of immunosuppression determines glucose tolerance after living-donor liver transplantation

scientific article published in April 2006

Managing end-of-life decision making in intensive care medicine--a perspective from Charité Hospital, Germany

scientific article

Measurement of upper eyelid implants curvature by ultrasound

scientific article published in May 2005

Menopausal symptoms in an intercultural context: a comparison between German women, Chinese women and migrant Chinese women using the Menopause Rating Scale (MRS II).

scientific article

Migration and symptom reporting at menopause: a comparative survey of migrant women from Turkey in Berlin, German women in Berlin, and women in Istanbul

scientific article

Minor Postoperative Increases of Creatinine Are Associated with Higher Mortality and Longer Hospital Length of Stay in Surgical Patients

scientific article

Mortality associated with administration of high-dose tranexamic acid and aprotinin in primary open-heart procedures: a retrospective analysis

scientific article published on 3 August 2010

Myocardial function in older male amateur marathon runners: assessment by tissue Doppler echocardiography, speckle tracking, and cardiac biomarkers

scientific article

Myocardial ischemia and cytokine response are associated with subsequent onset of infections after noncardiac surgery

scientific article

Neuraxial anesthesia for pain control after cesarean section: a prospective randomized trial comparing three different neuraxial techniques in clinical practice

scientific article published on 24 July 2015

Neuromyelitis optica: Evaluation of 871 attacks and 1,153 treatment courses

scientific article

Nonexcitable muscle membrane predicts intensive care unit-acquired paresis in mechanically ventilated, sedated patients

scientific article published in September 2009

Noninvasive detection of coronary artery stenoses with multislice computed tomography or magnetic resonance imaging

scientific article published on September 2006

Noninvasive monitoring of myocardial function after surgical and cytostatic therapy in a peritoneal metastasis rat model: assessment with tissue Doppler and non-Doppler 2D strain echocardiography

scientific article

Nucleated red blood cells as predictors of mortality in patients with acute respiratory distress syndrome (ARDS): an observational study

scientific article published on 27 March 2018

Observational clinical study on organ dysfunction associated with dosing of antibiotics in a paediatric intensive care unit

scientific article

Oral high-dose atorvastatin treatment in relapsing-remitting multiple sclerosis

scientific article

Outcome after surgery for prosthetic valve endocarditis and the impact of preoperative treatment

scientific article published on 16 May 2014

Patient Empowerment Improved Perioperative Quality of Care in Cancer Patients Aged ≥ 65 Years - A Randomized Controlled Trial

scientific article published on 17 September 2015

Patient safety in anaesthesia: assessment of status quo in the Berlin-Brandenburg area, Germany

scientific article published in October 2011

Periodic limb movements during REM sleep in multiple sclerosis: a previously undescribed entity

scientific article

Perioperative Care and the Importance of Continuous Quality Improvement--A Controlled Intervention Study in Three Tanzanian Hospitals

scientific article published on September 2015

Perioperative indocyanine green clearance is predictive for prolonged intensive care unit stay after coronary artery bypass grafting--an observational study

scientific article published on 14 September 2009

Peripheral intravenous cannulation with support of infrared laser vein viewing system in a pre-operation setting in pediatric patients

scientific article published on 21 September 2015

Perivascular spaces--MRI marker of inflammatory activity in the brain?

scientific article published on August 2008

Polymorphisms of the toll-like receptor 2 and 4 genes are associated with faster progression and a more severe course of sepsis in critically ill patients

scientific article

Poor Sleep in Multiple Sclerosis Correlates with Beck Depression Inventory Values, but Not with Polysomnographic Data

scientific article

Postoperative cognitive dysfunction: computerized and conventional tests showed only moderate inter-rater reliability

scientific article published on 28 May 2010

Potential role of autoantibodies belonging to the immunoglobulin G-3 subclass in cardiac dysfunction among patients with dilated cardiomyopathy

scientific article published on 01 November 2002

Potential role of humoral immunity in cardiac dysfunction of patients suffering from dilated cardiomyopathy

scientific article published on 01 August 2004

Practice and Effectiveness of Outpatient Psycho-Oncological Counseling for Cancer Patients

scientific article published on August 23, 2010

Practice of sedation and analgesia in German intensive care units: results of a national survey

scientific article

Predictive ability of the stability and workload index for transfer score to predict unplanned readmissions after ICU discharge

scientific article

Predictors of survival in critically ill patients with acute respiratory distress syndrome (ARDS): an observational study

scientific article

Preoperative oral carbohydrate administration to ASA III-IV patients undergoing elective cardiac surgery

scientific article published in November 2006

Preoperative short-course radiotherapy versus combined radiochemotherapy in locally advanced rectal cancer: a multi-centre prospectively randomised study of the Berlin Cancer Society

scientific article

Prevention and therapy of alcohol withdrawal on intensive care units: systematic review of controlled trials.

scientific article

Preventive antibacterial therapy in acute ischemic stroke: a randomized controlled trial

scientific article

Prolonged intensive care unit stay in cardiac surgery: risk factors and long-term-survival.

scientific article published in March 2006

Prone position during ECMO is safe and improves oxygenation

scientific article published on 2 October 2013

Randomised, double-blind study of the effects of oxybutynin, tolterodine, trospium chloride and placebo on sleep in healthy young volunteers

scientific article published in January 2003

Randomized controlled clinical trial evaluating multiplex polymerase chain reaction for pathogen identification and therapy adaptation in critical care patients with pulmonary or abdominal sepsis

scientific article

Readiness to change and therapy outcomes of an innovative psychotherapy program for surgical patients: results from a randomized controlled trial

scientific article published on 29 December 2017

Recombinant activated factor VII for refractory bleeding after cardiac surgery--a retrospective analysis of safety and efficacy

scientific article

Recombinant activated factor VIIa for the treatment of bleeding in major abdominal surgery including vascular and urological surgery: a review and meta-analysis of published data

scientific article

Reference data for the Thiemann-Nitz method of assessing skeletal age for the purpose of forensic age estimation

scientific article

Removal of cardiodepressant antibodies in dilated cardiomyopathy by immunoadsorption

scientific article

Reversal of apixaban induced alterations in haemostasis by different coagulation factor concentrates in patients after hip or knee replacement surgery

scientific article

Risk factors in critical illness myopathy during the early course of critical illness: a prospective observational study

scientific article

Rocuronium reversed by sugammadex versus mivacurium during high-risk eye surgery: an institutional anaesthetic practice evaluation.

scientific article published on 9 August 2013

Routine delirium monitoring is independently associated with a reduction of hospital mortality in critically ill surgical patients: A prospective, observational cohort study

scientific article published on 07 June 2016

Sentinel lymph node biopsy in colon cancer: a prospective multicenter trial

scientific article published in June 2007

Serum HER-2/neu as a prediction and monitoring parameter in a phase II study with weekly paclitaxel in metastatic breast cancer

scientific article

Sleep Disorders Reduce Health-Related Quality of Life in Multiple Sclerosis (Nottingham Health Profile Data in Patients with Multiple Sclerosis)

scientific article

Smoking, Gender, and Overweight Are Important Influencing Factors on Monocytic HLA-DR before and after Major Cancer Surgery

scientific article published on 8 August 2017

Socioeconomic factors, hazardous alcohol consumption, and smoking in patients with minor trauma in an inner-city emergency department

scientific article

Standard operating procedures for antibiotic therapy and the occurrence of acute kidney injury: a prospective, clinical, non-interventional, observational study

scientific article

Studies on the time frame for ossification of the medial clavicular epiphyseal cartilage in conventional radiography

scientific article published on October 8, 2003

TNF-related apoptosis inducing ligand (TRAIL) as a potential response marker for interferon-beta treatment in multiple sclerosis

scientific article published on June 2003

Tea-induced improvement of endothelial function in humans: No role for epigallocatechin gallate (EGCG).

scientific article published on 23 May 2017

Thawed solvent/detergent-treated plasma: too precious to be wasted after 6 hours?

scientific article published on 28 March 2012

The course of serum HER-2/neu levels as an independent prognostic factor for survival in metastatic breast cancer

scientific article

The effect of computerized tailored brief advice on at-risk drinking in subcritically injured trauma patients.

scientific article published in October 2006

The growth of uterine myomas in untreated women: influence factors and ultrasound monitoring

scientific article

The impact of an hematocrit of 20% during normothermic cardiopulmonary bypass for elective low risk coronary artery bypass graft surgery on oxygen delivery and clinical outcome--a randomized controlled study [ISRCTN35655335]

scientific article (publication date: 2006)

Thermoradiotherapy Using Interstitial Self-Regulating Thermoseeds: An Intermediate Analysis of a Phase II Trial

scientific article published on 01 May 2004

Thoracoscopic thymectomy with the da Vinci robotic system for myasthenia gravis

scientific article published in January 2008

Three-year survival after four major post-cardiac operative complications.

scientific article published in November 2006

Transient ischemic attacks before ischemic stroke: preconditioning the human brain? A multicenter magnetic resonance imaging study

scientific article published on 12 February 2004

Treatment of sleep disorders may improve fatigue in multiple sclerosis

scientific article

Trichuris suis ova in relapsing-remitting multiple sclerosis and clinically isolated syndrome (TRIOMS): study protocol for a randomized controlled trial

scientific article published on 25 April 2013

Validation of common classification systems for assessing the mineralization of third molars

scientific article published on 6 November 2004

Validity and reliability of the DDS for severity of delirium in the ICU.

scientific article published in January 2005

WITHDRAWN: Protracted intensive care unit-stay >14 days in cardiac surgery: risk factors and long-term survival

retracted scientific article published on 21 February 2006

Whole-body vibration to prevent intensive care unit-acquired weakness: safety, feasibility, and metabolic response

scientific article published on 09 January 2017