Search filters

List of works by Richard B S Roden

A Bayesian design for phase I cancer therapeutic vaccine trials

scientific article published on 25 October 2018

A batch-effect adjusted Simon's two-stage design for cancer vaccine clinical studies

scientific article published on 21 August 2020

A bis-benzylidine piperidone targeting proteasome ubiquitin receptor RPN13/ADRM1 as a therapy for cancer

scientific article published on December 2013

A common requirement for p21c-ras function in the mitogenic signaling pathways of Swiss 3T3 fibroblasts.

scientific article published on December 1993

A multimeric L2 vaccine for prevention of animal papillomavirus infections.

scientific article published on 13 September 2011

A papillomavirus-like particle (VLP) vaccine displaying HPV16 L2 epitopes induces cross-neutralizing antibodies to HPV11.

scientific article

A protective and broadly cross-neutralizing epitope of human papillomavirus L2.

scientific article

A serologically identified tumor antigen encoded by a homeobox gene promotes growth of ovarian epithelial cells

scholarly article

Aberrant expression of homeobox gene HOXA7 is associated with müllerian-like differentiation of epithelial ovarian tumors and the generation of a specific autologous antibody response ⬇️

scientific article published on December 11, 2001

An integrated proteomic and glycoproteomic approach uncovers differences in glycosylation occupancy from benign and malignant epithelial ovarian tumors.

scientific article

Antigen-specific immunotherapy of cervical and ovarian cancer

scientific article

Application of Bayesian modeling of autologous antibody responses against ovarian tumor-associated antigens to cancer detection

scientific article published in February 2006

Assessment of plasma DNA levels, allelic imbalance, and CA 125 as diagnostic tests for cancer

scientific article published on November 2002

Assessment of the serological relatedness of genital human papillomaviruses by hemagglutination inhibition

scientific article published in May 1996

B lymphocyte activation by human papillomavirus-like particles directly induces Ig class switch recombination via TLR4-MyD88

scientific article published on 01 June 2005

Bis-benzylidine Piperidone RA190 treatment of hepatocellular carcinoma via binding RPN13 and inhibiting NF-κB signaling

scientific article published on 06 May 2020

CD80 in immune suppression by mouse ovarian carcinoma-associated Gr-1+CD11b+ myeloid cells

scientific article published on July 2006

Capsid display of a conserved human papillomavirus L2 peptide in the adenovirus 5 hexon protein: a candidate prophylactic hpv vaccine approach

scientific article

Capsomer vaccines protect mice from vaginal challenge with human papillomavirus

scientific article (publication date: 2011)

Cell surface-binding motifs of L2 that facilitate papillomavirus infection

scientific article

Cervarix: a vaccine for the prevention of HPV 16, 18-associated cervical cancer.

scientific article published on March 2008

Characterization of a human papillomavirus type 16 variant-dependent neutralizing epitope ⬇️

scientific article published on August 1, 1997

Chemotherapy Acts as an Adjuvant to Convert the Tumor Microenvironment into a Highly Permissive State for Vaccination-Induced Antitumor Immunity ⬇️

scientific article published on February 15, 2013

Chimeric L1-L2 virus-like particles as potential broad-spectrum human papillomavirus vaccines

scientific article published on 29 July 2009

Chimeric papillomavirus virus-like particles elicit antitumor immunity against the E7 oncoprotein in an HPV16 tumor model

scientific article published in February 1998

Chirality and asymmetry increase the potency of candidate ADRM1/RPN13 inhibitors

scientific article published on 10 September 2021

Claudin-containing exosomes in the peripheral circulation of women with ovarian cancer

scientific article

Co-administration with DNA encoding papillomavirus capsid proteins enhances the antitumor effects generated by therapeutic HPV DNA vaccination

scientific article published on 25 June 2015

Combination of proteasome and HDAC inhibitors for uterine cervical cancer treatment

scientific article published on January 2009

Comparison of candidate serologic markers for type I and type II ovarian cancer ⬇️

scientific article published on June 24, 2011

Concatenated multitype L2 fusion proteins as candidate prophylactic pan-human papillomavirus vaccines

scientific article (publication date: 3 June 2009)

Control of HPV infection and related cancer through vaccination

scientific article

Covalent Rpn13-Binding Inhibitors for the Treatment of Ovarian Cancer

article published in 2018

Cross-neutralization of cutaneous and mucosal Papillomavirus types with anti-sera to the amino terminus of L2.

scientific article

Current Status of Human Papillomavirus Vaccines ⬇️

scientific article (publication date: July 2010)

Delivery of telomerase reverse transcriptase small interfering RNA in complex with positively charged single-walled carbon nanotubes suppresses tumor growth

scientific article published on 01 August 2006

Detection and localization of surgically resectable cancers with a multi-analyte blood test.

scientific article published on 18 January 2018

Detection of somatic TP53 mutations in tampons of patients with high-grade serous ovarian cancer

scientific article

Developing vaccines against minor capsid antigen L2 to prevent papillomavirus infection

scientific article

Development of AAVLP(HPV16/31L2) Particles as Broadly Protective HPV Vaccine Candidate ⬇️

scientific article published on June 27, 2012

Developments in L2-based human papillomavirus (HPV) vaccines

scientific article published on 23 November 2016

Diffuse mesothelin expression correlates with prolonged patient survival in ovarian serous carcinoma

scientific article published in February 2006

Durable immunity to oncogenic human papillomaviruses elicited by adjuvanted recombinant Adeno-associated virus-like particle immunogen displaying L2 17-36 epitopes

scientific article

Early and consistent overexpression of ADRM1 in ovarian high-grade serous carcinoma.

scientific article

Early detection and treatment of ovarian cancer: shifting from early stage to minimal volume of disease based on a new model of carcinogenesis

scientific article published on April 2008

Efficacy of RG1-VLP vaccination against infections with genital and cutaneous human papillomaviruses.

scientific article published on 10 May 2013

Efficient self-assembly of human papillomavirus type 16 L1 and L1-L2 into virus-like particles

scientific article published on December 1993

Enhanced cancer radiotherapy through immunosuppressive stromal cell destruction in tumors

scientific article

Enhancement of sindbis virus self-replicating RNA vaccine potency by targeting antigen to endosomal/lysosomal compartments

scientific article

Epithelial boost enhances antigen expression by vaccinia virus for the generation of potent CD8+ T cell-mediated antitumor immunity following DNA priming vaccination

article

Evaluation of DNA from the Papanicolaou test to detect ovarian and endometrial cancers

scientific article

Evaluation of cancer-associated myositis and scleroderma autoantibodies in breast cancer patients without rheumatic disease.

scientific article published on 19 June 2017

Evaluation of osteopenia and osteoporosis in younger breast cancer survivors compared with cancer-free women: a prospective cohort study

scientific article published on 13 November 2018

Expression pattern and subcellular localization of human papillomavirus minor capsid protein L2

scientific article published on 18 December 2008

Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma

scientific article

GATA-3 expression in trophoblastic tissues: an immunohistochemical study of 445 cases, including diagnostic utility

scientific article

Generation and characterization of DNA vaccines targeting the nucleocapsid protein of severe acute respiratory syndrome coronavirus

scientific article published on May 2004

Generation and characterization of a preventive and therapeutic HPV DNA vaccine

scientific article

HLA-DQB1*02-restricted HPV-16 E7 peptide-specific CD4+ T-cell immune responses correlate with regression of HPV-16-associated high-grade squamous intraepithelial lesions

scientific article

HPV Pseudovirions As DNA Delivery Vehicles ⬇️

scientific article published on April 1, 2011

HPV-16 L1 VLP vaccine elicits a broad-spectrum of cytokine responses in whole blood

scientific article published on 01 May 2005

HPV16 L1 capsid protein expressed from viable adenovirus recombinants elicits neutralizing antibody in mice

scientific article published on 18 July 2006

How will HPV vaccines affect cervical cancer?

scientific article

Human papillomavirus type 16 virus-like particles expressed in attenuated Salmonella typhimurium elicit mucosal and systemic neutralizing antibodies in mice ⬇️

scientific article published on August 1, 1997

Human papillomavirus type-16 virus-like particles activate complementary defense responses in key dendritic cell subpopulations

scientific article published in August 2004

Human papillomavirus vaccines for the prevention and treatment of cervical cancer.

scientific article

Identification of Anti-CA125 Antibody Responses in Ovarian Cancer Patients by a Novel Deep Sequence-Coupled Biopanning Platform

scientific article published on 20 November 2015

Identification of glycoproteins associated with different histological subtypes of ovarian tumors using quantitative glycoproteomics

scientific article

Identification of molecular pathway aberrations in uterine serous carcinoma by genome-wide analyses.

scientific article

Immune responses in macaques to a prototype recombinant adenovirus live oral human papillomavirus 16 vaccine

scientific article

Immunizing against Anogenital Cancer: HPV Vaccines

scientific article

Immunohistochemical detection of human papillomavirus capsid proteins L1 and L2 in squamous intraepithelial lesions: potential utility in diagnosis and management ⬇️

scientific article published on September 21, 2012

Immunologic Control of Mus musculus Papillomavirus Type 1.

scientific article published on 23 October 2015

Immunologic responses to a novel DNA vaccine targeting human papillomavirus-11 E6E7.

scientific article

Immunoprevention of human papillomavirus-associated malignancies

scientific article

Immunotherapy for gynaecological malignancies.

scientific article

Impact of inhibitors and L2 antibodies upon the infectivity of diverse alpha and beta human papillomavirus types

scientific article

In Vivo Mechanisms of Vaccine-Induced Protection against HPV Infection ⬇️

scientific article published on September 16, 2010

In vitro generation and type-specific neutralization of a human papillomavirus type 16 virion pseudotype

scientific article published in September 1996

Incorporation of RG1 epitope concatemers into a self-adjuvanting Flagellin-L2 vaccine broaden durable protection against cutaneous challenge with diverse human papillomavirus genotypes

scientific article published on August 2017

Incorporation of RG1 epitope into HPV16L1-VLP does not compromise L1-specific immunity

scientific article published on 27 May 2019

Increased plasma DNA integrity in cancer patients.

scientific article

Infectivity of murine papillomavirus in the surgical byproducts of treated tail warts

scientific article published on 01 May 2019

Insights into the role of innate immunity in cervicovaginal papillomavirus infection from studies using gene deficient mice

scientific article published on 15 April 2020

Interaction of L2 with beta-actin directs intracellular transport of papillomavirus and infection

scientific article

Interaction of papillomaviruses with the cell surface

scientific article published on November 1994

Interaction of tSNARE syntaxin 18 with the papillomavirus minor capsid protein mediates infection

scientific article

L1 interaction domains of papillomavirus l2 necessary for viral genome encapsidation

scientific article

L2, the minor capsid protein of papillomavirus ⬇️

scientific article published on May 17, 2013

Local HPV Recombinant Vaccinia Boost Following Priming with an HPV DNA Vaccine Enhances Local HPV-Specific CD8+ T-cell-Mediated Tumor Control in the Genital Tract

scientific article published on 29 September 2015

Low doses of flagellin-L2 multimer vaccines protect against challenge with diverse papillomavirus genotypes

scientific article

Measurement of neutralizing serum antibodies of patients vaccinated with human papillomavirus L1 or L2-based immunogens using furin-cleaved HPV Pseudovirions

scientific article

Mechanisms of human papillomavirus type 16 neutralization by l2 cross-neutralizing and l1 type-specific antibodies

scientific article published on 27 February 2008

Minor capsid protein of human genital papillomaviruses contains subdominant, cross-neutralizing epitopes

scientific article published on 01 May 2000

Mucosal but not parenteral immunization with purified human papillomavirus type 16 virus-like particles induces neutralizing titers of antibodies throughout the estrous cycle of mice

scientific article

Multivalent human papillomavirus l1 DNA vaccination utilizing electroporation

scientific article

Murine skin and vaginal mucosa are similarly susceptible to infection by pseudovirions of different papillomavirus classifications and species

scientific article published on 15 September 2012

Myosin II co-chaperone general cell UNC-45 overexpression is associated with ovarian cancer, rapid proliferation, and motility

scientific article

Nasal immunization of mice with human papillomavirus type 16 virus-like particles elicits neutralizing antibodies in mucosal secretions

scientific article

Neutralization of bovine papillomavirus by antibodies to L1 and L2 capsid proteins ⬇️

scientific article published on November 1, 1994

Novel structural features of bovine papillomavirus capsid revealed by a three-dimensional reconstruction to 9 A resolution

scientific article published on May 1997

Opportunities and challenges for human papillomavirus vaccination in cancer.

scientific article published on 2 March 2018

Opportunities to improve the prevention and treatment of cervical cancer

scientific article published on August 2007

Optimization of RG1-VLP vaccine performance in mice with novel TLR4 agonists

scientific article published on 10 December 2020

Optimization of heterologous DNA-prime, protein boost regimens and site of vaccination to enhance therapeutic immunity against human papillomavirus-associated disease

scientific article published on 25 February 2016

Optimization of multimeric human papillomavirus L2 vaccines

scientific article

PD-1 blockade synergizes with intratumoral vaccination of a therapeutic HPV protein vaccine and elicits regression of tumor in a preclinical model

scientific article published on 27 October 2020

Papillomavirus Is Resistant to Desiccation ⬇️

scientific article published on October 1, 1997

Papillomavirus L1 capsids agglutinate mouse erythrocytes through a proteinaceous receptor

scientific article published in August 1995

Papillomavirus capsid mutation to escape dendritic cell-dependent innate immunity in cervical cancer

scientific article

Papillomavirus infection requires gamma secretase

scientific article

Papillomavirus prophylactic vaccines: established successes, new approaches

scientific article

Papillomavirus-like particles stimulate murine bone marrow-derived dendritic cells to produce alpha interferon and Th1 immune responses via MyD88.

scientific article published on October 2004

Personalized chemotherapy profiling using cancer cell lines from selectable mice

scientific article

Photonic approach to the selective inactivation of viruses with a near-infrared subpicosecond fiber laser

scientific article

Phylogenetic considerations in designing a broadly protective multimeric L2 vaccine

scientific article published on 27 March 2013

Positively charged termini of the L2 minor capsid protein are necessary for papillomavirus infection

scientific article

Preparation and properties of a papillomavirus infectious intermediate and its utility for neutralization studies

scientific article published on 20 December 2013

Prevalence of the alternative lengthening of telomeres telomere maintenance mechanism in human cancer subtypes

scientific article

Preventative and therapeutic vaccines for cervical cancer

scientific article published on August 2003

Prevention of cancer by prophylactic human papillomavirus vaccines

scientific article

Production and characterization of a novel HPV anti-L2 monoclonal antibody panel

scientific article published on 28 August 2018

Production of Furin-Cleaved Papillomavirus Pseudovirions and Their Use for In Vitro Neutralization Assays of L1- or L2-Specific Antibodies

scientific article

Progress and prospects for L2-based human papillomavirus vaccines

scientific article published on 22 February 2016

Progress in L2-Based Prophylactic Vaccine Development for Protection against Diverse Human Papillomavirus Genotypes and Associated Diseases

scientific article published on 01 October 2020

Progress in the development of a cervical cancer vaccine.

scientific article published in September 2006

Prophylactic immunization with human papillomavirus vaccines induces oral immunity in mice

scientific article

Protection against heterologous human papillomavirus challenge by a synthetic lipopeptide vaccine containing a broadly cross-neutralizing epitope of L2.

scholarly article

Protection of rabbits against challenge with rabbit papillomaviruses by immunization with the N terminus of human papillomavirus type 16 minor capsid antigen L2.

scientific article

RPN13/ADRM1 inhibitor reverses immunosuppression by myeloid-derived suppressor cells

scientific article published on 17 September 2016

Role of L2 cysteines in papillomavirus infection and neutralization

scientific article published on 27 October 2009

Roles of Fc domain and exudation in L2 antibody-mediated protection against human papillomavirus.

scientific article

Safety and immunogenicity trial in adult volunteers of a human papillomavirus 16 L1 virus-like particle vaccine

scientific article

Sequential cisplatin therapy and vaccination with HPV16 E6E7L2 fusion protein in saponin adjuvant GPI-0100 for the treatment of a model HPV16+ cancer

scientific article

Seroepidemiology of Human Papillomavirus 16 (HPV16) L2 and Generation of L2-Specific Human Chimeric Monoclonal Antibodies

scientific article published on 13 May 2015

Simultaneous inhibition of deubiquitinating enzymes (DUBs) and autophagy synergistically kills breast cancer cells

scientific article published on February 2015

Small cell carcinoma of the ovary, hypercalcemic type, displays frequent inactivating germline and somatic mutations in SMARCA4

scientific article

Small-molecule RA-9 inhibits proteasome-associated DUBs and ovarian cancer in vitro and in vivo via exacerbating unfolded protein responses

scientific article

Spontaneous and Vaccine-Induced Clearance of Mus Musculus Papillomavirus 1 Infection

scientific article

Spontaneous regression of high-grade cervical dysplasia: effects of human papillomavirus type and HLA phenotype

scientific article published in July 2005

Stressing the ubiquitin-proteasome system without 20S proteolytic inhibition selectively kills cervical cancer cells

scientific article

Structure-function analyses of candidate small molecule RPN13 inhibitors with antitumor properties

scientific article published on 15 January 2020

The PD-1 and PD-L1 pathway in recurrent respiratory papillomatosis

scientific article

The Papillomavirus Minor Capsid Protein, L2, Induces Localization of the Major Capsid Protein, L1, and the Viral Transcription/Replication Protein, E2, to PML Oncogenic Domains ⬇️

scientific article published on January 1, 1998

The Proteasome Ubiquitin Receptor hRpn13 and Its Interacting Deubiquitinating Enzyme Uch37 Are Required for Proper Cell Cycle Progression

scientific article published on 23 February 2016

The Replicative Consequences of Papillomavirus E2 Protein Binding to the Origin Replication Factor ORC2

scientific article

The estrogen receptor-alpha S118P variant does not affect breast cancer incidence or response to endocrine therapies

scientific article published in 2018

The future of vaccines for cervical cancer

scientific article published on May 2008

The high risk HPV16 L2 minor capsid protein has multiple transport signals that mediate its nucleocytoplasmic traffic

scientific article published on 6 December 2011

The high-mobility group A1 gene up-regulates cyclooxygenase 2 expression in uterine tumorigenesis

scientific article published in May 2007

The impact of preventive HPV vaccination.

scientific article published on October 2006

The positively charged termini of L2 minor capsid protein required for bovine papillomavirus infection function separately in nuclear import and DNA binding

scientific article published on December 2004

Tissue-spanning redox gradient-dependent assembly of native human papillomavirus type 16 virions

scientific article

Toll-like receptor agonist imiquimod facilitates antigen-specific CD8+ T-cell accumulation in the genital tract leading to tumor control through IFNγ

scientific article

Towards global prevention of human papillomavirus-induced cancer

scientific article published on February 2008

Two antibodies that neutralize papillomavirus by different mechanisms show distinct binding patterns at 13 Å resolution ⬇️

scientific article published on August 7, 1998

Ubiquitin proteasome system stress underlies synergistic killing of ovarian cancer cells by bortezomib and a novel HDAC6 inhibitor

scientific article

Ubiquitin-proteasome system stress sensitizes ovarian cancer to proteasome inhibitor-induced apoptosis

scientific article published on April 2006

Utility of GATA3 immunohistochemistry in differentiating urothelial carcinoma from prostate adenocarcinoma and squamous cell carcinomas of the uterine cervix, anus, and lung

scientific article

Vaccination of healthy volunteers with human papillomavirus type 16 L2E7E6 fusion protein induces serum antibody that neutralizes across papillomavirus species

scientific article published on 01 December 2006

Vaccination to prevent and treat cervical cancer

scientific article

Vaccination with HPV16 L2E6E7 fusion protein in GPI-0100 adjuvant elicits protective humoral and cell-mediated immunity.

scientific article

Vaccination with multimeric L2 fusion protein and L1 VLP or capsomeres to broaden protection against HPV infection

scientific article

Vaccines against human papillomavirus

scientific article published on January 2007

Virus-like particles for the prevention of human papillomavirus-associated malignancies ⬇️

scientific article published on February 1, 2013

Weight change in breast cancer survivors compared to cancer-free women: a prospective study in women at familial risk of breast cancer

scientific article

p53 autoantibodies, cytokine levels and ovarian carcinogenesis

scientific article published on 26 April 2009

α,β-Unsaturated Carbonyl System of Chalcone-Based Derivatives Is Responsible for Broad Inhibition of Proteasomal Activity and Preferential Killing of Human Papilloma Virus (HPV) Positive Cervical Cancer Cells ⬇️

scientific article published on December 27, 2010

Paulina is supported by:

About Paulina

Help