List of works - Markus Wirtz

A mechanistic model of the cysteine synthase complex.

scientific article

A molecular switch in sulfur metabolism to reduce arsenic and enrich selenium in rice grain

scientific article published on 02 March 2021

Affinity Purification of O-Acetylserine(thiol)lyase from Chlorella sorokiniana by Recombinant Proteins from Arabidopsis thaliana

scientific article published on 4 August 2014

Allosterically gated enzyme dynamics in the cysteine synthase complex regulate cysteine biosynthesis in Arabidopsis thaliana

scientific article

Analysis of the Arabidopsis O-acetylserine(thiol)lyase gene family demonstrates compartment-specific differences in the regulation of cysteine synthesis

scientific article published on 25 January 2008

Apoplastic gamma-glutamyl transferase activity encoded by GGT1 and GGT2 is important for vegetative and generative development.

scientific article published on 10 March 2017

Arabidopsis glutathione reductase 2 is indispensable in plastids, while mitochondrial glutathione is safeguarded by additional reduction and transport systems

scientific article published on 28 August 2019

Balancing metabolites in drought: the sulfur assimilation conundrum

scientific article published on 02 October 2012

Characterization of the serine acetyltransferase gene family of Vitis vinifera uncovers differences in regulation of OAS synthesis in woody plants.

scientific article published on 17 February 2015

Chloroplast Acetyltransferase NSI Is Required for State Transitions in Arabidopsis thaliana

scientific article published on 02 July 2018

Cotranslational N-degron masking by acetylation promotes proteome stability in plants

scientific article published on 10 February 2022

Cysteine biosynthesis, in concert with a novel mechanism, contributes to sulfide detoxification in mitochondria of Arabidopsis thaliana.

scientific article published in July 2012

Differential N-end Rule Degradation of RIN4/NOI Fragments Generated by the AvrRpt2 Effector Protease

scientific article published on 21 June 2019

Differential regulation of the expression of two high-affinity sulfate transporters, SULTR1.1 and SULTR1.2, in Arabidopsis.

scientific article published on 9 April 2008

Disruption of adenosine-5'-phosphosulfate kinase in Arabidopsis reduces levels of sulfated secondary metabolites

scientific article published on 20 March 2009

Dominant-negative modification reveals the regulatory function of the multimeric cysteine synthase protein complex in transgenic tobacco

scientific article published on 9 February 2007

Downregulation of N-terminal acetylation triggers ABA-mediated drought responses in Arabidopsis

scientific article

Drought stress in maize causes differential acclimation responses of glutathione and sulfur metabolism in leaves and roots

scientific article

Drought-Enhanced Xylem Sap Sulfate Closes Stomata by Affecting ALMT12 and Guard Cell ABA Synthesis

scientific article published on 26 April 2017

Dual lysine and N-terminal acetyltransferases reveal the complexity underpinning protein acetylation

scientific article published on 01 July 2020

Dynamic plastid redox signals integrate gene expression and metabolism to induce distinct metabolic states in photosynthetic acclimation in Arabidopsis

scientific article published on 08 September 2009

Ectopically expressed glutaredoxin ROXY19 negatively regulates the detoxification pathway in Arabidopsis thaliana

scientific article

Effects of fou8/fry1 mutation on sulfur metabolism: is decreased internal sulfate the trigger of sulfate starvation response?

scientific article

Enzymes of cysteine synthesis show extensive and conserved modifications patterns that include N(α)-terminal acetylation

scientific article published on 24 July 2010

Evidence for a SAL1-PAP chloroplast retrograde pathway that functions in drought and high light signaling in Arabidopsis

scientific article published on 29 November 2011

Evidence for several cysteine transport mechanisms in the mitochondrial membranes of Arabidopsis thaliana.

scientific article

Expression profiling of metabolic genes in response to methyl jasmonate reveals regulation of genes of primary and secondary sulfur-related pathways in Arabidopsis thaliana

scientific article published on 15 November 2005

Functional analysis of the cysteine synthase protein complex from plants: structural, biochemical and regulatory properties.

scientific article

Generation of Se-fortified broccoli as functional food: impact of Se fertilization on S metabolism

scientific article published on 11 November 2010

Improved sulfur nutrition provides the basis for enhanced production of sulfur-containing defense compounds in Arabidopsis thaliana upon inoculation with Alternaria brassicicola

scientific article published in May 2012

Inhibition of 5'-methylthioadenosine metabolism in the Yang cycle alters polyamine levels, and impairs seedling growth and reproduction in Arabidopsis

scientific article published on 19 March 2010

Integration of light and metabolic signals for stem cell activation at the shoot apical meristem.

scientific article

Interactions between chromium and sulfur metabolism in Brassica juncea

scientific article published on 23 June 2008

MTHFD1 controls DNA methylation in Arabidopsis ⬇️

scientific article published on 13 June 2016

Methionine salvage and S-adenosylmethionine: essential links between sulfur, ethylene and polyamine biosynthesis.

scientific article published on April 2013

Mitochondrial Dihydrolipoyl Dehydrogenase Activity Shapes Photosynthesis and Photorespiration of Arabidopsis thaliana

scientific article

Mitochondrial alternative <scp>NADH</scp> dehydrogenases <scp>NDA1</scp> and <scp>NDA2</scp> promote survival of reoxygenation stress in Arabidopsis by safeguarding photosynthesis and limiting <scp>ROS</scp> generation

scientific article published on 4 February 2023

Mitochondrial cysteine synthase complex regulates O-acetylserine biosynthesis in plants

scientific article published on 22 June 2012

Mitochondrial serine acetyltransferase functions as a pacemaker of cysteine synthesis in plant cells.

scientific article published on 27 August 2008

Molecular Biology, Biochemistry and Cellular Physiology of Cysteine Metabolism in Arabidopsis thaliana

scientific article published on 16 December 2011

Molecular identification and functional characterization of the first Nα-acetyltransferase in plastids by global acetylome profiling

scientific article

Monitoring global protein thiol-oxidation and protein S-mycothiolation in Mycobacterium smegmatis under hypochlorite stress.

scientific article published on 26 April 2017

N-terminal acetylation: an essential protein modification emerges as an important regulator of stress responses

scientific article published on 01 August 2018

NAA50 is an enzymatically active Nα-acetyltransferase that is crucial for development and regulation of stress responses

scientific article published on 27 May 2020

NatB-Mediated N-Terminal Acetylation Affects Growth and Biotic Stress Responses

scientific article published on 19 November 2019

Nuclear Localised MORE SULPHUR ACCUMULATION1 Epigenetically Regulates Sulphur Homeostasis in Arabidopsis thaliana.

scientific article

O-acetylserine (thiol) lyase: an enigmatic enzyme of plant cysteine biosynthesis revisited in Arabidopsis thaliana

scientific article published on 16 July 2004

OsMTN encodes a 5'-methylthioadenosine nucleosidase that is up-regulated during submergence-induced ethylene synthesis in rice (Oryza sativa L.).

scientific article published on 05 March 2007

Overexpression of serine acetlytransferase produced large increases in O-acetylserine and free cysteine in developing seeds of a grain legume

scientific article

Plant glutathione biosynthesis revisited: redox-mediated activation of glutamylcysteine ligase does not require homo-dimerization

article

ROS-Mediated Inhibition of S-nitrosoglutathione Reductase Contributes to the Activation of Anti-oxidative Mechanisms.

scientific article

Recycling of methylthioadenosine is essential for normal vascular development and reproduction in Arabidopsis

scientific article published on 16 February 2012

Redox-mediated kick-start of mitochondrial energy metabolism drives resource-efficient seed germination

scientific article published on 23 December 2019

Regulation of sulfate uptake and expression of sulfate transporter genes in Brassica oleracea as affected by atmospheric H(2)S and pedospheric sulfate nutrition

scientific article published on 17 September 2004

Regulation of sulphate assimilation by glutathione in poplars (Populus tremula x P. alba) of wild type and overexpressing gamma-glutamylcysteine synthetase in the cytosol

scientific article published on 12 March 2004

Relation between chemotaxis and consumption of amino acids in bacteria

scientific article

Restricting glutathione biosynthesis to the cytosol is sufficient for normal plant development

scientific article

Retrograde plastid redox signals in the expression of nuclear genes for chloroplast proteins of Arabidopsis thaliana.

scientific article published on 23 November 2004

SAM levels, gene expression of SAM synthetase, methionine synthase and ACC oxidase, and ethylene emission from N. suaveolens flowers.

scientific article

SULTR3;1 is a chloroplast-localized sulfate transporter in Arabidopsis thaliana

scientific article published on 28 December 2012

SULTR3s Function in Chloroplast Sulfate Uptake and Affect ABA Biosynthesis and the Stress Response

scientific article published on 05 March 2019

Selenate and molybdate alter sulfate transport and assimilation in Brassica juncea L. Czern.: Implications for phytoremediation

scientific article published in January 2012

Structural and functional characterization of the N-terminal acetyltransferase Naa50

scientific article published on 22 December 2020

Structure and function of the hetero-oligomeric cysteine synthase complex in plants

scientific article published on 18 August 2010

Successful fertilization requires the presence of at least one major O-acetylserine(thiol)lyase for cysteine synthesis in pollen of Arabidopsis.

scientific article published on 3 September 2013

Sulfate availability affects ABA levels and germination response to ABA and salt stress in Arabidopsis thaliana.

scientific article

Sulfate is Incorporated into Cysteine to Trigger ABA Production and Stomatal Closure

scientific article published on 11 December 2018

Sulfate-Induced Stomata Closure Requires the Canonical ABA Signal Transduction Machinery

article

Sulfide detoxification in plant mitochondria

scientific article published on 08 January 2015

Sulfite reductase defines a newly discovered bottleneck for assimilatory sulfate reduction and is essential for growth and development in Arabidopsis thaliana.

scientific article published on 27 April 2010

Sulfur availability regulates plant growth via glucose-TOR signaling

scientific article published on 27 October 2017

Sulfur metabolic engineering enhances cadmium stress tolerance and root to shoot iron translocation in Brassica napus L

scientific article published on 18 April 2020

Sulfur partitioning between glutathione and protein synthesis determines plant growth.

scientific article

Sulphite oxidase as key enzyme for protecting plants against sulphur dioxide

article

Sultr4;1 mutant seeds of Arabidopsis have an enhanced sulphate content and modified proteome suggesting metabolic adaptations to altered sulphate compartmentalization

scientific article

System analysis of metabolism and the transcriptome in Arabidopsis thaliana roots reveals differential co-regulation upon iron, sulfur and potassium deficiency ⬇️

scientific article published on 10 October 2016

Tandem Fluorescent Protein Timers for Noninvasive Relative Protein Lifetime Measurement in Plants

scientific article published on 14 March 2019

Targeted systems biology profiling of tomato fruit reveals coordination of the Yang cycle and a distinct regulation of ethylene biosynthesis during postclimacteric ripening.

scientific article published on 13 September 2012

The Arabidopsis Nα -acetyltransferase NAA60 locates to the plasma membrane and is vital for the high salt stress response

scientific article published on 16 June 2020

The Arabidopsis THADA homologue modulates TOR activity and cold acclimation

scientific article published on 19 September 2018

The NADPH-dependent thioredoxin system constitutes a functional backup for cytosolic glutathione reductase in Arabidopsis

scientific article

The Recovery from Sulfur Starvation Is Independent from the mRNA Degradation Initiation Enzyme PARN in Arabidopsis

scientific article published on 27 September 2019

The analysis of Arabidopsis nicotianamine synthase mutants reveals functions for nicotianamine in seed iron loading and iron deficiency responses.

scientific article published on 20 March 2009

The glyceraldehyde-3-phosphate dehydrogenase GapDH of Corynebacterium diphtheriae is redox-controlled by protein S-mycothiolation under oxidative stress.

scientific article published on 10 July 2017

The mitochondrial sulfur dioxygenase ETHYLMALONIC ENCEPHALOPATHY PROTEIN1 is required for amino acid catabolism during carbohydrate starvation and embryo development in Arabidopsis.

scientific article published in April 2014

The redox-sensitive module of cyclophilin 20-3, 2-cysteine peroxiredoxin and cysteine synthase integrates sulfur metabolism and oxylipin signaling in the high light acclimation response

scientific article published on 23 June 2017

The relevance of compartmentation for cysteine synthesis in phototrophic organisms

scientific article published on 29 April 2012

The role of compartment-specific cysteine synthesis for sulfur homeostasis during H2S exposure in Arabidopsis.

scientific article published on 20 November 2014

The role of methionine recycling for ethylene synthesis in Arabidopsis.

scientific article published on 27 November 2006

The seed composition of Arabidopsis mutants for the group 3 sulfate transporters indicates a role in sulfate translocation within developing seeds

scientific article published on 11 August 2010

The significance of cysteine synthesis for acclimation to high light conditions

scientific article published on January 2014

The versatile interactome of chloroplast ribosomes revealed by affinity purification mass spectrometry

scientific article published on 16 December 2020

Toward new perspectives on the interaction of iron and sulfur metabolism in plants.

scientific article published on 02 October 2013

Transcriptome profiling of genes differentially modulated by sulfur and chromium identifies potential targets for phytoremediation and reveals a complex S-Cr interplay on sulfate transport regulation in B. juncea

scientific article published on 01 September 2012

Two N-terminal acetyltransferases antagonistically regulate the stability of a nod-like receptor in Arabidopsis.

scientific article published on 12 May 2015

Use of biomolecular interaction analysis to elucidate the regulatory mechanism of the cysteine synthase complex from Arabidopsis thaliana

scientific article

Vacuolar nicotianamine has critical and distinct roles under iron deficiency and for zinc sequestration in Arabidopsis.

scientific article

List of works by Markus Wirtz

A mechanistic model of the cysteine synthase complex.

A molecular switch in sulfur metabolism to reduce arsenic and enrich selenium in rice grain

Affinity Purification of O-Acetylserine(thiol)lyase from Chlorella sorokiniana by Recombinant Proteins from Arabidopsis thaliana

Allosterically gated enzyme dynamics in the cysteine synthase complex regulate cysteine biosynthesis in Arabidopsis thaliana

Analysis of the Arabidopsis O-acetylserine(thiol)lyase gene family demonstrates compartment-specific differences in the regulation of cysteine synthesis

Apoplastic gamma-glutamyl transferase activity encoded by GGT1 and GGT2 is important for vegetative and generative development.

Arabidopsis glutathione reductase 2 is indispensable in plastids, while mitochondrial glutathione is safeguarded by additional reduction and transport systems

Balancing metabolites in drought: the sulfur assimilation conundrum

Characterization of the serine acetyltransferase gene family of Vitis vinifera uncovers differences in regulation of OAS synthesis in woody plants.

Chloroplast Acetyltransferase NSI Is Required for State Transitions in Arabidopsis thaliana

Cotranslational N-degron masking by acetylation promotes proteome stability in plants

Cysteine biosynthesis, in concert with a novel mechanism, contributes to sulfide detoxification in mitochondria of Arabidopsis thaliana.

Differential N-end Rule Degradation of RIN4/NOI Fragments Generated by the AvrRpt2 Effector Protease

Differential regulation of the expression of two high-affinity sulfate transporters, SULTR1.1 and SULTR1.2, in Arabidopsis.

Disruption of adenosine-5'-phosphosulfate kinase in Arabidopsis reduces levels of sulfated secondary metabolites

Dominant-negative modification reveals the regulatory function of the multimeric cysteine synthase protein complex in transgenic tobacco

Downregulation of N-terminal acetylation triggers ABA-mediated drought responses in Arabidopsis

Drought stress in maize causes differential acclimation responses of glutathione and sulfur metabolism in leaves and roots

Drought-Enhanced Xylem Sap Sulfate Closes Stomata by Affecting ALMT12 and Guard Cell ABA Synthesis

Dual lysine and N-terminal acetyltransferases reveal the complexity underpinning protein acetylation

Dynamic plastid redox signals integrate gene expression and metabolism to induce distinct metabolic states in photosynthetic acclimation in Arabidopsis

Ectopically expressed glutaredoxin ROXY19 negatively regulates the detoxification pathway in Arabidopsis thaliana

Effects of fou8/fry1 mutation on sulfur metabolism: is decreased internal sulfate the trigger of sulfate starvation response?

Enzymes of cysteine synthesis show extensive and conserved modifications patterns that include N(α)-terminal acetylation

Evidence for a SAL1-PAP chloroplast retrograde pathway that functions in drought and high light signaling in Arabidopsis

Evidence for several cysteine transport mechanisms in the mitochondrial membranes of Arabidopsis thaliana.

Expression profiling of metabolic genes in response to methyl jasmonate reveals regulation of genes of primary and secondary sulfur-related pathways in Arabidopsis thaliana

Functional analysis of the cysteine synthase protein complex from plants: structural, biochemical and regulatory properties.

Generation of Se-fortified broccoli as functional food: impact of Se fertilization on S metabolism

Improved sulfur nutrition provides the basis for enhanced production of sulfur-containing defense compounds in Arabidopsis thaliana upon inoculation with Alternaria brassicicola

Inhibition of 5'-methylthioadenosine metabolism in the Yang cycle alters polyamine levels, and impairs seedling growth and reproduction in Arabidopsis

Integration of light and metabolic signals for stem cell activation at the shoot apical meristem.

Interactions between chromium and sulfur metabolism in Brassica juncea

MTHFD1 controls DNA methylation in Arabidopsis ⬇️

Methionine salvage and S-adenosylmethionine: essential links between sulfur, ethylene and polyamine biosynthesis.

Mitochondrial Dihydrolipoyl Dehydrogenase Activity Shapes Photosynthesis and Photorespiration of Arabidopsis thaliana

Mitochondrial alternative <scp>NADH</scp> dehydrogenases <scp>NDA1</scp> and <scp>NDA2</scp> promote survival of reoxygenation stress in Arabidopsis by safeguarding photosynthesis and limiting <scp>ROS</scp> generation

Mitochondrial cysteine synthase complex regulates O-acetylserine biosynthesis in plants

Mitochondrial serine acetyltransferase functions as a pacemaker of cysteine synthesis in plant cells.

Molecular Biology, Biochemistry and Cellular Physiology of Cysteine Metabolism in Arabidopsis thaliana

Molecular identification and functional characterization of the first Nα-acetyltransferase in plastids by global acetylome profiling

Monitoring global protein thiol-oxidation and protein S-mycothiolation in Mycobacterium smegmatis under hypochlorite stress.

N-terminal acetylation: an essential protein modification emerges as an important regulator of stress responses

NAA50 is an enzymatically active Nα-acetyltransferase that is crucial for development and regulation of stress responses

NatB-Mediated N-Terminal Acetylation Affects Growth and Biotic Stress Responses

Nuclear Localised MORE SULPHUR ACCUMULATION1 Epigenetically Regulates Sulphur Homeostasis in Arabidopsis thaliana.

O-acetylserine (thiol) lyase: an enigmatic enzyme of plant cysteine biosynthesis revisited in Arabidopsis thaliana

OsMTN encodes a 5'-methylthioadenosine nucleosidase that is up-regulated during submergence-induced ethylene synthesis in rice (Oryza sativa L.).

Overexpression of serine acetlytransferase produced large increases in O-acetylserine and free cysteine in developing seeds of a grain legume

Plant glutathione biosynthesis revisited: redox-mediated activation of glutamylcysteine ligase does not require homo-dimerization

ROS-Mediated Inhibition of S-nitrosoglutathione Reductase Contributes to the Activation of Anti-oxidative Mechanisms.

Recycling of methylthioadenosine is essential for normal vascular development and reproduction in Arabidopsis

Redox-mediated kick-start of mitochondrial energy metabolism drives resource-efficient seed germination

Regulation of sulfate uptake and expression of sulfate transporter genes in Brassica oleracea as affected by atmospheric H(2)S and pedospheric sulfate nutrition

Regulation of sulphate assimilation by glutathione in poplars (Populus tremula x P. alba) of wild type and overexpressing gamma-glutamylcysteine synthetase in the cytosol

Relation between chemotaxis and consumption of amino acids in bacteria

Restricting glutathione biosynthesis to the cytosol is sufficient for normal plant development

Retrograde plastid redox signals in the expression of nuclear genes for chloroplast proteins of Arabidopsis thaliana.

SAM levels, gene expression of SAM synthetase, methionine synthase and ACC oxidase, and ethylene emission from N. suaveolens flowers.

SULTR3;1 is a chloroplast-localized sulfate transporter in Arabidopsis thaliana

SULTR3s Function in Chloroplast Sulfate Uptake and Affect ABA Biosynthesis and the Stress Response

Selenate and molybdate alter sulfate transport and assimilation in Brassica juncea L. Czern.: Implications for phytoremediation

Structural and functional characterization of the N-terminal acetyltransferase Naa50

Structure and function of the hetero-oligomeric cysteine synthase complex in plants

Successful fertilization requires the presence of at least one major O-acetylserine(thiol)lyase for cysteine synthesis in pollen of Arabidopsis.

Sulfate availability affects ABA levels and germination response to ABA and salt stress in Arabidopsis thaliana.

Sulfate is Incorporated into Cysteine to Trigger ABA Production and Stomatal Closure

Sulfate-Induced Stomata Closure Requires the Canonical ABA Signal Transduction Machinery

Sulfide detoxification in plant mitochondria

Sulfite reductase defines a newly discovered bottleneck for assimilatory sulfate reduction and is essential for growth and development in Arabidopsis thaliana.

Sulfur availability regulates plant growth via glucose-TOR signaling

Sulfur metabolic engineering enhances cadmium stress tolerance and root to shoot iron translocation in Brassica napus L

Sulfur partitioning between glutathione and protein synthesis determines plant growth.

Sulphite oxidase as key enzyme for protecting plants against sulphur dioxide

Sultr4;1 mutant seeds of Arabidopsis have an enhanced sulphate content and modified proteome suggesting metabolic adaptations to altered sulphate compartmentalization

System analysis of metabolism and the transcriptome in Arabidopsis thaliana roots reveals differential co-regulation upon iron, sulfur and potassium deficiency ⬇️

Tandem Fluorescent Protein Timers for Noninvasive Relative Protein Lifetime Measurement in Plants

Targeted systems biology profiling of tomato fruit reveals coordination of the Yang cycle and a distinct regulation of ethylene biosynthesis during postclimacteric ripening.

The Arabidopsis Nα -acetyltransferase NAA60 locates to the plasma membrane and is vital for the high salt stress response