List of works by Vassilis Gorgoulis

A Functional Immune System Is Required for the Systemic Genotoxic Effects of Localized Irradiation

scientific article published on 06 December 2018

A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence

scientific article published on 10 January 2018

A study concerning morphometry of abdominal aorta branches and abdominal viscera: relations and correlation

scientific article published on 14 September 2015

ARF: a versatile DNA damage response ally at the crossroads of development and tumorigenesis.

scientific article published on 22 July 2014

Age-associated inflammation connects RAS-induced senescence to stem cell dysfunction and epidermal malignancy

scientific article

Ageing, Cellular Senescence and Neurodegenerative Disease

scientific article published on 27 September 2018

Alterations in the Proliferating Compartment of Gastric Mucosa during Helicobacter Pylori Infection: The Putative Role of Epithelial Cells Expressing p27kip1 ⬇️

scientific article published on November 1, 2003

Annexin A3 is a mammary marker and a potential neoplastic breast cell therapeutic target

scientific article published on 4 June 2015

Apidima Cave fossils provide earliest evidence of Homo sapiens in Eurasia

scientific article published on 10 July 2019

Apoptosis or senescence? Which exit route do epithelial cells and fibroblasts preferentially follow?

scientific article published on 6 April 2016

Applying Broadband Dielectric Spectroscopy (BDS) for the Biophysical Characterization of Mammalian Tissues under a Variety of Cellular Stresses.

scientific article

Assessing drug development risk using Big Data and Machine Learning

scientific article published on 22 December 2020

CRISPR-Cas9-mediated induction of large chromosomal inversions in human bronchial epithelial cells

scientific article published on 18 March 2022

Chronic expression of p16INK4a in the epidermis induces Wnt-mediated hyperplasia and promotes tumor initiation

scientific article published on 01 June 2020

Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing

scientific article published on 20 June 2016

Combined Virtual and Experimental Screening for CK1 Inhibitors Identifies a Modulator of p53 and Reveals Important Aspects of in Silico Screening Performance

scientific article published on 6 October 2017

Conditioning attenuates kidney and heart injury in rats following transient suprarenal occlusion of the abdominal aorta

scientific article published on 19 March 2020

Cura"x"ing Cancer and Beyond

scientific article published on 03 December 2018

DNA Damage Response and Autophagy: A Meaningful Partnership

scientific article

DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas

scientific article published on 01 August 2018

DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas.

scientific article published on 27 October 2016

Deep learning: shaping the medicine of tomorrow

scientific article published on 19 February 2020

Defective DNA repair and chromatin organization in patients with quiescent systemic lupus erythematosus.

scientific article

Dual function of p38α MAPK in colon cancer: suppression of colitis-associated tumor initiation but requirement for cancer cell survival

scientific article

Erratum to ‘Exploring and exploiting the systemic effects of deregulated replication licensing’ [Seminars in Cancer Biology 37–38C, (2016) 3–15]

scientific article published on 21 February 2017

Ex vivo culture of cells derived from circulating tumour cell xenograft to support small cell lung cancer research and experimental therapeutics

scientific article published on 13 December 2018

Geminin ablation in vivo enhances tumorigenesis through increased genomic instability

scientific article published on 21 August 2018

HPV-associated lung cancers: an international pooled analysis.

scientific article

HPV16 E6/E7 expression in circulating tumor cells in oropharyngeal squamous cell cancers: A pilot study

scientific article published on 09 May 2019

Hepatocyte autotaxin expression promotes liver fibrosis and cancer.

scientific article

Hyperactivation of Nrf2 increases stress tolerance at the cost of aging acceleration due to metabolic deregulation

scientific article published on 10 December 2018

Immunohisto(cyto)chemistry: an old time classic tool driving modern oncological therapies

scientific article published on 27 November 2018

In situ evidence of cellular senescence in Thymic Epithelial Cells (TECs) during human thymic involution.

scientific article published on 25 February 2018

Inflammation, DNA Damage, Helicobacter pylori and Gastric Tumorigenesis

scientific article published on 27 February 2017

Integrating the DNA damage and protein stress responses during cancer development and treatment.

scientific article

Ionizing radiation-mediated premature senescence and paracrine interactions with cancer cells enhance the expression of syndecan 1 in human breast stromal fibroblasts: the role of TGF-β.

scientific article published on 12 July 2016

Karyotypic Flexibility of the Complex Cancer Genome and the Role of Polyploidization in Maintenance of Structural Integrity of Cancer Chromosomes

scientific article published on 05 March 2020

LATS1 and LATS2 suppress breast cancer progression by maintaining cell identity and metabolic state

scientific article published on 30 October 2018

Localized Synchrotron Irradiation of Mouse Skin Induces Persistent Systemic Genotoxic and Immune Responses

scientific article published on 7 November 2017

MST2 kinase suppresses rDNA transcription in response to DNA damage by phosphorylating nucleolar histone H2B.

scientific article

MiR-signing gastrointestinal (con-)tract cancer

scientific article published on 25 March 2017

Mitochondrial Homeostasis and Cellular Senescence

scientific article published on 06 July 2019

Monitoring Autophagy Immunohistochemically and Ultrastructurally during Human Head and Neck Carcinogenesis. Relationship with the DNA Damage Response Pathway.

scientific article published on 7 September 2017

Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246.

scientific article published on 22 February 2018

Mutant p53 gain of function underlies high expression levels of colorectal cancer stem cells markers.

scientific article published on 18 January 2018

Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability.

scientific article published on 16 March 2018

N-bromotaurine surrogates for loss of antiproliferative response and enhances cisplatin efficacy in cancer cells with impaired glucocorticoid receptor.

scientific article published on 21 March 2016

Oncogene-induced reactive oxygen species fuel hyperproliferation and DNA damage response activation

scientific article

Oncogene-induced senescence: the bright and dark side of the response ⬇️

scientific article published on September 16, 2010

Oncogenic Role of the Ec Peptide of the IGF-1Ec Isoform in Prostate Cancer

scientific article published on 6 January 2015

Progression of mouse skin carcinogenesis is associated with the orchestrated deregulation of mir-200 family members, mir-205 and their common targets

scientific article published on 27 August 2015

Proteasome dysfunction induces excessive proteome instability and loss of mitostasis that can be mitigated by enhancing mitochondrial fusion or autophagy

scientific article published on 19 April 2019

Proteome Stability as a Key Factor of Genome Integrity

scientific article published on 22 September 2017

RNF20 Links Histone H2B Ubiquitylation with Inflammation and Inflammation-Associated Cancer

scientific article published on 3 February 2016

RNF20 and histone H2B ubiquitylation exert opposing effects in Basal-Like versus luminal breast cancer

scientific article

SCF(Cyclin F)-dependent degradation of CDC6 suppresses DNA re-replication

scientific article published on 28 January 2016

Senescence and senotherapeutics: a new field in cancer therapy

scientific article published on 16 August 2018

Sudan Black B, The Specific Histochemical Stain for Lipofuscin: A Novel Method to Detect Senescent Cells.

scientific article published on January 2017

Systemic dna damage: Mechanisms, effects and mitigation strategies.

scientific article published on 22 April 2016

The Janus face of p21.

scientific article published on 29 July 2016

The Typhoid Toxin Promotes Host Survival and the Establishment of a Persistent Asymptomatic Infection

scientific article

The oncogenic JUNB/CD30 axis contributes to cell cycle deregulation in ALK+ anaplastic large cell lymphoma.

scientific article published on 22 August 2014

The role of oxidative DNA damage in radiation induced bystander effect

scientific article published on 11 February 2014

Tissue-infiltrating macrophages mediate an exosome-based metabolic reprogramming upon DNA damage

scientific article published on 02 January 2020

Unique Spatial Immune Profiling in Pancreatic Ductal Adenocarcinoma with Enrichment of Exhausted and Senescent T Cells and Diffused CD47-SIRPα Expression

scientific article published on 07 July 2020

Unravelling a p73-regulated network: The role of a novel p73-dependent target, MIR3158, in cancer cell migration and invasiveness.

scientific article published on 2 December 2016

Unreplicated DNA remaining from unperturbed S phases passes through mitosis for resolution in daughter cells

scientific article published on 11 August 2016

Upregulation of Human Endogenous Retroviruses in Bronchoalveolar Lavage Fluid of COVID-19 Patients

scientific article published on 15 May 2020

Validation and development of MTH1 inhibitors for treatment of cancer.

scientific article

Versican modulates tumor-associated macrophage properties to stimulate mesothelioma growth

scientific article published on 02 November 2018

p21WAF1/Cip1 - PCNA: Fatal attraction

scientific article published on 11 August 2016

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