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List of works by Olav Larsen

Attenuation of chemokine receptor function and surface expression as an immunomodulatory strategy employed by human cytomegalovirus is linked to vGPCR US28.

scientific article published on 12 December 2016

Biased and g protein-independent signaling of chemokine receptors

scientific article

Biased signaling of lipids and allosteric actions of synthetic molecules for GPR119.

scientific article published on 25 August 2016

Discovery and Characterization of Biased Allosteric Agonists of the Chemokine Receptor CXCR3

article

GLP-1 Val8: A Biased GLP-1R Agonist with Altered Binding Kinetics and Impaired Release of Pancreatic Hormones in Rats

scientific article published on 19 January 2021

Molecular Mechanism of Action for Allosteric Modulators and Agonists in CC-chemokine Receptor 5 (CCR5).

scientific article published on 10 November 2016

Mutational analysis of CCL20 reveals flexibility of N-terminal amino acid composition and length

scientific article published on 01 August 2018

Natural nitration of CXCL12 reduces its signaling capacity and chemotactic activity in vitro and abrogates intra-articular lymphocyte recruitment in vivo.

scientific article published on 23 August 2016

Protein engineering of the chemokine CCL20 prevents psoriasiform dermatitis in an IL-23-dependent murine model.

scientific article published on 6 November 2017

Rationally designed chemokine-based toxin targeting the viral G protein-coupled receptor US28 potently inhibits cytomegalovirus infection in vivo

scientific article published on 15 June 2015

Role of Conserved Disulfide Bridges and Aromatic Residues in Extracellular Loop 2 of Chemokine Receptor CCR8 for Chemokine and Small Molecule Binding

scientific article

Structure-function guided modeling of chemokine-GPCR specificity for the chemokine XCL1 and its receptor XCR1

scientific article published on 03 September 2019

Truncation of CXCL12 by CD26 reduces its CXC chemokine receptor 4- and atypical chemokine receptor 3-dependent activity on endothelial cells and lymphocytes

scientific article published on 16 March 2017

Varicella zoster virus glycoprotein C increases chemokine-mediated leukocyte migration.

scientific article

Viral GPCR US28 can signal in response to chemokine agonists of nearly unlimited structural degeneracy.

scientific article published on 8 June 2018

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