List of works - Josefa Mallol

A hybrid indoloquinolizidine peptide as allosteric modulator of dopamine D1 receptors

scientific article

A2A adenosine receptor ligand binding and signalling is allosterically modulated by adenosine deaminase

scientific article published in May 2011

Adenosine/dopamine receptor-receptor interactions in the central nervous system

scholarly article by Rafael Franco et al published January 2001 in Drug Development Research

Basic concepts in G-protein-coupled receptor homo- and heterodimerization.

scientific article published on 2 November 2007

Cannabinoid receptors CB1 and CB2 form functional heteromers in brain

scientific article published on 24 April 2012

Circadian-related heteromerization of adrenergic and dopamine D₄ receptors modulates melatonin synthesis and release in the pineal gland

scientific article

Coaggregation, cointernalization, and codesensitization of adenosine A2A receptors and dopamine D2 receptors

scientific article (publication date: 17 May 2002)

Cocaine inhibits dopamine D2 receptor signaling via sigma-1-D2 receptor heteromers

scientific article

Detection of heteromerization of more than two proteins by sequential BRET-FRET.

scientific article

Detection of heteromers formed by cannabinoid CB1, dopamine D2, and adenosine A2A G-protein-coupled receptors by combining bimolecular fluorescence complementation and bioluminescence energy transfer.

scientific article

Detection of receptor heteromers involving dopamine receptors by the sequential BRET-FRET technology

scientific article published in January 2013

Dimer-based model for heptaspanning membrane receptors

scientific article published on 01 July 2005

Direct involvement of sigma-1 receptors in the dopamine D1 receptor-mediated effects of cocaine

scientific article

Dopamine D1-histamine H3 receptor heteromers provide a selective link to MAPK signaling in GABAergic neurons of the direct striatal pathway

scientific article

Functional μ-Opioid-Galanin Receptor Heteromers in the Ventral Tegmental Area.

scientific article published on 22 December 2016

GPCR homomers and heteromers: a better choice as targets for drug development than GPCR monomers?

scientific article published on 05 August 2009

Gi protein coupling to adenosine A1-A2A receptor heteromers in human brain caudate nucleus.

scientific article published on 13 May 2010

Heptaspanning membrane receptors and cytoskeletal/scaffolding proteins: focus on adenosine, dopamine, and metabotropic glutamate receptor function

scientific article

Homodimerization of adenosine A2A receptors: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer

scientific article published on February 2004

Human adenosine deaminase as an allosteric modulator of human A(1) adenosine receptor: abolishment of negative cooperativity for [H](R)-pia binding to the caudate nucleus

scientific article

Interactions between calmodulin, adenosine A2A, and dopamine D2 receptors

scientific article

Interactions between intracellular domains as key determinants of the quaternary structure and function of receptor heteromers

scientific article

Involvement of caveolin in ligand-induced recruitment and internalization of A(1) adenosine receptor and adenosine deaminase in an epithelial cell line

scientific article published on May 2001

L-DOPA disrupts adenosine A(2A)-cannabinoid CB(1)-dopamine D(2) receptor heteromer cross-talk in the striatum of hemiparkinsonian rats: biochemical and behavioral studies

scientific article published on 9 January 2014

L-DOPA-treatment in primates disrupts the expression of A(2A) adenosine-CB(1) cannabinoid-D(2) dopamine receptor heteromers in the caudate nucleus

scientific article

Ligand-induced caveolae-mediated internalization of A1 adenosine receptors: morphological evidence of endosomal sorting and receptor recycling

scientific article published on April 2003

Marked changes in signal transduction upon heteromerization of dopamine D1 and histamine H3 receptors

scientific article

Metabotropic glutamate type 1alpha receptor localizes in low-density caveolin-rich plasma membrane fractions

scientific article published in August 2003

Molecular mechanisms involved in the adenosine A and A receptor-induced neuronal differentiation in neuroblastoma cells and striatal primary cultures

scientific article

Mutual regulation between metabotropic glutamate type 1alpha receptor and caveolin proteins: from traffick to constitutive activity

scientific article published on October 2004

Novel pharmacological targets based on receptor heteromers

scientific article

Old and new ways to calculate the affinity of agonists and antagonists interacting with G-protein-coupled monomeric and dimeric receptors: the receptor-dimer cooperativity index.

scientific article published on 14 June 2007

Orexin-corticotropin-releasing factor receptor heteromers in the ventral tegmental area as targets for cocaine

scientific article published on April 2015

Partners for adenosine A1 receptors

scientific article

Presynaptic control of striatal glutamatergic neurotransmission by adenosine A1-A2A receptor heteromers

scientific article

Regulation of epithelial and lymphocyte cell adhesion by adenosine deaminase-CD26 interaction

scientific article

Regulation of heptaspanning-membrane-receptor function by dimerization and clustering

scientific article published on 01 May 2003

The adenosine A2A receptor interacts with the actin-binding protein alpha-actinin

scientific journal article

The catalytic site structural gate of adenosine deaminase allosterically modulates ligand binding to adenosine receptors

scientific article published on 27 November 2012

The neuronal Ca(2+) -binding protein 2 (NECAB2) interacts with the adenosine A(2A) receptor and modulates the cell surface expression and function of the receptor

scientific article

The two-state dimer receptor model: a general model for receptor dimers

scientific article published on 24 February 2006

Up-regulation of the Kv3.4 potassium channel subunit in early stages of Alzheimer's disease.

scientific article

Useful pharmacological parameters for G-protein-coupled receptor homodimers obtained from competition experiments. Agonist-antagonist binding modulation.

scientific article published on 28 July 2009

List of works by Josefa Mallol

A hybrid indoloquinolizidine peptide as allosteric modulator of dopamine D1 receptors

A2A adenosine receptor ligand binding and signalling is allosterically modulated by adenosine deaminase

Adenosine/dopamine receptor-receptor interactions in the central nervous system

Basic concepts in G-protein-coupled receptor homo- and heterodimerization.

Cannabinoid receptors CB1 and CB2 form functional heteromers in brain

Circadian-related heteromerization of adrenergic and dopamine D₄ receptors modulates melatonin synthesis and release in the pineal gland

Coaggregation, cointernalization, and codesensitization of adenosine A2A receptors and dopamine D2 receptors

Cocaine inhibits dopamine D2 receptor signaling via sigma-1-D2 receptor heteromers

Detection of heteromerization of more than two proteins by sequential BRET-FRET.

Detection of heteromers formed by cannabinoid CB1, dopamine D2, and adenosine A2A G-protein-coupled receptors by combining bimolecular fluorescence complementation and bioluminescence energy transfer.

Detection of receptor heteromers involving dopamine receptors by the sequential BRET-FRET technology

Dimer-based model for heptaspanning membrane receptors

Direct involvement of sigma-1 receptors in the dopamine D1 receptor-mediated effects of cocaine

Dopamine D1-histamine H3 receptor heteromers provide a selective link to MAPK signaling in GABAergic neurons of the direct striatal pathway

Functional μ-Opioid-Galanin Receptor Heteromers in the Ventral Tegmental Area.

GPCR homomers and heteromers: a better choice as targets for drug development than GPCR monomers?

Gi protein coupling to adenosine A1-A2A receptor heteromers in human brain caudate nucleus.

Heptaspanning membrane receptors and cytoskeletal/scaffolding proteins: focus on adenosine, dopamine, and metabotropic glutamate receptor function

Homodimerization of adenosine A2A receptors: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer

Human adenosine deaminase as an allosteric modulator of human A(1) adenosine receptor: abolishment of negative cooperativity for [H](R)-pia binding to the caudate nucleus

Interactions between calmodulin, adenosine A2A, and dopamine D2 receptors

Interactions between intracellular domains as key determinants of the quaternary structure and function of receptor heteromers

Involvement of caveolin in ligand-induced recruitment and internalization of A(1) adenosine receptor and adenosine deaminase in an epithelial cell line

L-DOPA disrupts adenosine A(2A)-cannabinoid CB(1)-dopamine D(2) receptor heteromer cross-talk in the striatum of hemiparkinsonian rats: biochemical and behavioral studies

L-DOPA-treatment in primates disrupts the expression of A(2A) adenosine-CB(1) cannabinoid-D(2) dopamine receptor heteromers in the caudate nucleus

Ligand-induced caveolae-mediated internalization of A1 adenosine receptors: morphological evidence of endosomal sorting and receptor recycling

Marked changes in signal transduction upon heteromerization of dopamine D1 and histamine H3 receptors

Metabotropic glutamate type 1alpha receptor localizes in low-density caveolin-rich plasma membrane fractions

Molecular mechanisms involved in the adenosine A and A receptor-induced neuronal differentiation in neuroblastoma cells and striatal primary cultures

Mutual regulation between metabotropic glutamate type 1alpha receptor and caveolin proteins: from traffick to constitutive activity

Novel pharmacological targets based on receptor heteromers

Old and new ways to calculate the affinity of agonists and antagonists interacting with G-protein-coupled monomeric and dimeric receptors: the receptor-dimer cooperativity index.

Orexin-corticotropin-releasing factor receptor heteromers in the ventral tegmental area as targets for cocaine

Partners for adenosine A1 receptors

Presynaptic control of striatal glutamatergic neurotransmission by adenosine A1-A2A receptor heteromers

Regulation of epithelial and lymphocyte cell adhesion by adenosine deaminase-CD26 interaction

Regulation of heptaspanning-membrane-receptor function by dimerization and clustering

The adenosine A2A receptor interacts with the actin-binding protein alpha-actinin

The catalytic site structural gate of adenosine deaminase allosterically modulates ligand binding to adenosine receptors

The neuronal Ca(2+) -binding protein 2 (NECAB2) interacts with the adenosine A(2A) receptor and modulates the cell surface expression and function of the receptor

The two-state dimer receptor model: a general model for receptor dimers

Up-regulation of the Kv3.4 potassium channel subunit in early stages of Alzheimer's disease.

Useful pharmacological parameters for G-protein-coupled receptor homodimers obtained from competition experiments. Agonist-antagonist binding modulation.