Search filters

List of works by Geoffrey L Greene

14q32-encoded microRNAs mediate an oligometastatic phenotype

scientific article

A "cross-stitched" peptide with improved helicity and proteolytic stability

scientific article published on 01 May 2018

A novel nuclear form of estradiol receptor in MCF-7 human breast cancer cells

scientific article published on 01 September 1984

A single domain of the estrogen receptor confers deoxyribonucleic acid binding and transcriptional activation of the rat prolactin gene.

scientific article published in January 1988

A structural explanation for ERalpha/ERbeta SERM discrimination.

scientific article published in January 2004

Activating ESR1 Mutations Differentially Affect the Efficacy of ER Antagonists.

scientific article published on 16 December 2016

Allosteric control of ligand selectivity between estrogen receptors alpha and beta: implications for other nuclear receptors

scientific article published on February 2004

An estrogen receptor-alpha knock-in mutation provides evidence of ligand-independent signaling and allows modulation of ligand-induced pathways in vivo

scientific article published on 13 March 2008

An immunocytochemical method for demonstrating estrogen receptor in human uterus using monoclonal antibodies to human estrophilin

scientific article published on 01 April 1984

An immunohistochemical evaluation of progesterone receptor in frozen sections, paraffin sections, and cytologic imprints of breast carcinomas ⬇️

scientific article published on January 15, 1991

Analysis of the structural core of the human estrogen receptor ligand binding domain by selective proteolysis/mass spectrometric analysis.

scientific article

Androgen receptor localization in different cell types of the adult rat prostate

scientific article

Antagonists for Constitutively Active Mutant Estrogen Receptors: Insights into the Roles of Antiestrogen-Core and Side-Chain

scientific article published on 26 November 2018

Antibodies to estrogen receptor: Immunochemical similarity of estrophilin from various mammalian species ⬇️

scientific article published on September 1, 1977

Antibodies to estrophilin: Comparison between rabbit and goat antisera ⬇️

scientific article published on 01 July 1979

CBP Is a dosage-dependent regulator of nuclear factor-kappaB suppression by the estrogen receptor

scientific article

Capture of associated targets on chromatin links long-distance chromatin looping to transcriptional coordination

scientific article published on 16 September 2016

Cell membrane and nuclear estrogen receptors (ERs) originate from a single transcript: studies of ERalpha and ERbeta expressed in Chinese hamster ovary cells

scientific article published in February 1999

Cellular progesterone receptor phosphorylation in response to ligands activating protein kinases

scientific article published on 01 August 1987

Characterization of the ovarian and reproductive abnormalities in prepubertal and adult estrogen non-responsive estrogen receptor alpha knock-in (ENERKI) mice

scientific article published on 23 July 2009

Characterization of the subunit nature of nuclear estrogen receptors by chemical cross-linking and dense amino acid labeling

article published in 1985

Comparison of an immunocytochemical assay for progesterone receptor with a biochemical method of measurement and immunocytochemical examination of the relationship between progesterone and estrogen receptors

scientific article published on 01 September 1989

Comparison of immunocytochemical and steroid-binding assays for estrogen receptor in human breast tumors

scientific article published on 01 January 1985

Conformation-specific affinity purification of proteins using engineered binding proteins: application to the estrogen receptor

scientific article published on 14 November 2005

Consensus statement: Expedition Inspiration fund for breast cancer research meeting 2002

scientific article published on 01 March 2003

Construction of cell lines that express high levels of the human estrogen receptor and are killed by estrogens

scientific article published on October 1990

Cross-talk between the ligand- and DNA-binding domains of estrogen receptor

scientific article published on 19 August 2013

Demonstration of steroid hormone receptors and steroid action in primary cultures of rat glial cells

scientific article published on March 1, 1992

Detection of the HER-2/neu proto-oncogene protein p185erbB2 by a novel monoclonal antibody (MAB-145ww) in breast cancer membranes from oestrogen and progesterone receptor assays

scientific article published on 01 January 1992

Differences between estrogen- and antiestrogen-estrogen receptor complexes from human breast tumors identified with an antibody raised against the estrogen receptor.

scientific article published in March 1984

Discovery of a glucocorticoid receptor (GR) activity signature using selective GR antagonism in ER-negative breast cancer.

scientific article published on 10 April 2018

ESR1 ligand-binding domain mutations in hormone-resistant breast cancer

scientific article

Elemental isomerism: a boron-nitrogen surrogate for a carbon-carbon double bond increases the chemical diversity of estrogen receptor ligands

scientific article

Endocrine Therapy-Resistant Breast Cancer Cells Are More Sensitive to Ceramide Kinase Inhibition and Elevated Ceramide Levels Than Therapy-Sensitive Breast Cancer Cells

scientific article published on 12 May 2022

Endoxifen, 4-Hydroxytamoxifen and an Estrogenic Derivative Modulate Estrogen Receptor Complex Mediated Apoptosis in Breast Cancer.

scientific article published on 8 May 2018

Estrogen Response Elements Function as Allosteric Modulators of Estrogen Receptor Conformation ⬇️

scientific article published on April 1, 1998

Estrogen and progesterone receptor measurements with monoclonal antibodies.

scientific article published on January 1988

Estrogen and progesterone receptor structure and action in breast cancer cells

scientific article published on January 1992

Estrogen and progestin receptors and aromatase activity in rhesus monkey prostate

scientific article published on 01 November 1988

Estrogen binding, receptor mRNA, and biologic response in osteoblast-like osteosarcoma cells

scientific article published on 01 July 1988

Estrogen inhibits vascular smooth muscle cell-dependent adventitial fibroblast migration in vitro

scientific article published in October 1999

Estrogen plus progesterone increases progestin receptor immunoreactivity in the brain of ovariectomized guinea pigs

scientific article published in December 1989

Estrogen receptor (alpha and beta) expression in the excurrent ducts of the adult male rat reproductive tract ⬇️

scientific article published on 01 November 1997

Estrogen receptor accessory proteins augment receptor-DNA interaction and DNA bending ⬇️

scientific article published on 01 September 1997

Estrogen receptor accessory proteins: effects on receptor-DNA interactions

scientific article

Estrogen receptor affinity and location of consensus and imperfect estrogen response elements influence transcription activation of simplified promoters

scientific article published on 01 June 1996

Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation.

scientific article published on 2 February 2016

Estrogen receptor determination in endometrial carcinoma: ligand binding assay versus enzyme immunoassay

scientific article published on 01 March 1995

Estrogen receptor expression in human breast cancer associated with an estrogen receptor gene restriction fragment length polymorphism

scientific article published on 01 January 1989

Estrogen receptor gene methylation in human breast tumors

scientific article published on 01 July 1990

Estrogen receptor immunocytochemistry in endometrial carcinoma: a prognostic marker for survival

scientific article published on 01 October 1996

Estrogen receptor localization in formalin-fixed, paraffin-embedded endometrium and endometriotic tissues

scientific article published in January 1987

Estrogen receptor localization in the female genital tract

scientific article published in May 1986

Estrogen receptor pathways to AP-1.

scientific article

Estrogen receptor transformation in MCF-7 breast cancer cells: characterization by immunochemical and sedimentation analyses

scientific article published on January 1984

Estrogen receptors in human prostate: evidence for multiple binding sites

scientific article published on 01 July 1983

Estrogen receptors in the nuclear matrix: direct demonstration using monoclonal antireceptor antibody

scientific article published on 01 May 1987

Estrogen receptors, antibodies and hormone dependent cancer

scientific article published on 01 January 1984

Estrogen-dependent and -independent estrogen receptor-alpha signaling separately regulate male fertility

scientific article published on 05 March 2009

Estrophilin: pro and anti

scientific article published in January 1980

Examining the pathogenesis of breast cancer using a novel agent-based model of mammary ductal epithelium dynamics

scientific article

Expression of an estrogen receptor by human coronary artery and umbilical vein endothelial cells.

scientific article

Genomic agonism and phenotypic antagonism between estrogen and progesterone receptors in breast cancer.

scientific article published on 24 June 2016

Green tea catechins inhibit angiogenesis through suppression of STAT3 activation

scientific article published on 28 September 2008

Human estrogen receptor bound to an estrogen response element bends DNA

scientific article published on 01 March 1993

Identification of cysteine 530 as the covalent attachment site of an affinity-labeling estrogen (ketononestrol aziridine) and antiestrogen (tamoxifen aziridine) in the human estrogen receptor.

scientific article

Identification of ligands with bicyclic scaffolds provides insights into mechanisms of estrogen receptor subtype selectivity.

scientific article published on 28 April 2006

Immunochemical studies of estrogen receptors

scientific article published on January 1984

Immunochemical studies of estrogen receptors

scientific article published on January 1987

Immunocytochemical Localization of Estrogen Receptors in the Macaque Reproductive Tract with Monoclonal Antiestrophilins* ⬇️

scientific article published on 01 June 1984

Immunocytochemical analysis of estrogen receptors as a predictor of prognosis in breast cancer patients: comparison with quantitative biochemical methods

scientific article published on 01 February 1989

Immunocytochemical assay for androgen receptors in prostate cancer: a prospective study of 63 cases with long-term follow-up

scientific article published on 01 November 1994

Immunocytochemical assay for estrogen receptor with monoclonal antibody D753P gamma in routinely processed formaldehyde-fixed breast tissue. Comparison with frozen section assay and with monoclonal antibody H222

scientific article published on 01 June 1993

Immunocytochemical assay of progesterone receptors in paraffin-embedded specimens of endometrial carcinoma and hyperplasia: a preliminary evaluation

scientific article published on September 1989

Immunocytochemical determination of estrogen receptor, progesterone receptor, and 1,25-dihydroxyvitamin D3 receptor in breast cancer and relationship to prognosis ⬇️

scientific article published on January 1, 1991

Immunocytochemical estrogen and progestin receptor assays in breast cancer with monoclonal antibodies. Histopathologic, demographic, and biochemical correlations and relationship to endocrine response and survival

scientific article published on 01 October 1990

Immunocytochemical identification of estrogen receptor in ovarian carcinomas. Localization with monoclonal estrophilin antibodies compared with biochemical assays

scientific article published in September 1985

Immunohistochemical analysis of estrogen and progesterone receptors in benign breast diseases

scientific article published in January 1991

Immunohistochemical analysis of human uterine estrogen and progesterone receptors throughout the menstrual cycle

scientific article published on 01 August 1988

Immunohistochemical assessment of estrogen and progesterone receptors in stored imprints and cryostat sections of breast carcinomas

scientific article published on 01 August 1989

Immunohistochemical assessment of estrogen receptor distribution in the human endometrium throughout the menstrual cycle

scientific article published on 01 November 1984

Immunohistochemical localization of progesterone receptor in human decidua of early pregnancy ⬇️

scientific article published on January 1, 1992

Immunostaining of estrogen receptor in paraffin sections of breast carcinomas using monoclonal antibody D75P3 gamma: effects of fixation

scientific article published in December 1987

In vivo imaging reveals estrogen receptor's hidden personality

scientific article published on 01 January 2003

Inhibition of estrogen receptor action by a naturally occurring variant in human breast tumors ⬇️

scientific article published on January 15, 1992

Inhibition of mammary tumorigenesis in the C3(1)/SV40 mouse model by green tea.

scientific article published on 5 May 2007

Interaction of [3H] estradiol - and [3H] monohydroxytamoxifen-estrogen receptor complexes with a monoclonal antibody

scientific article published on 01 January 1983

Interferon-Stimulated Genes Are Transcriptionally Repressed by PR in Breast Cancer

scientific article

Isolation and Cloning of Human Peroxisome Proliferator Activated Receptor Gamma CDNA ⬇️

scientific article published on 01 January 1997

Label-free detection of protein-protein interactions on biochips

scientific article published in August 2005

Ligand control of coregulator recruitment to nuclear receptors

scientific article

Ligand-Modulated Regulation of Progesterone Receptor Messenger Ribonucleic Acid and Protein in Human Breast Cancer Cell Lines ⬇️

scientific article published on 01 March 1988

Localization of progesterone receptor with monoclonal antibodies to the human progestin receptor

scientific article published on 01 March 1988

Mapping ERβ genomic binding sites reveals unique genomic features and identifies EBF1 as an ERβ interactor

scientific article

MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11.

scientific article published on January 2013

MicroRNA-30c targets cytoskeleton genes involved in breast cancer cell invasion.

scientific article published on 7 December 2012

Modulation of alphaCaMKII signaling by rapid ERalpha action

scientific article published on 23 May 2008

Molecular basis of agonism and antagonism in the oestrogen receptor

scientific article

Molecular characterization by mass spectrometry of the human estrogen receptor ligand-binding domain expressed in Escherichia coli

scientific article published on June 1995

Molecular characterization of a B-ring unsaturated estrogen: Implications for conjugated equine estrogen components of Premarin

scientific article

Molecular cloning of the chicken progesterone receptor

scientific article

Monoclonal antibodies as probes for estrogen receptor detection and characterization

scientific article published on 01 March 1982

Monoclonal antibodies localize oestrogen receptor in the nuclei of target cells

scientific article published in Nature

Monoclonal antibodies to estrophilin: probes for the study of estrogen receptors

scientific article

Monoclonal antibodies to human estrogen receptor

scientific article

NFκB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses

scientific article

Next-Generation ERα Inhibitors for Endocrine-Resistant ER+ Breast Cancer

scientific article published on 01 April 2019

Nuclear receptor ligands and cofactor recruitment: is there a coactivator "on deck"?

scientific article

Overcoming mutation-based resistance to antiandrogens with rational drug design

scientific article (publication date: 9 April 2013)

Phosphorylation of the chicken progesterone receptor

scientific article published on 01 January 1987

Plasma membrane estrogen receptors exist and functions as dimers

scientific article

Progesterone Receptor Gene Restriction Fragment Length Polymorphisms in Human Breast Tumors ⬇️

scientific article published on August 21, 1991

Progesterone receptor distribution in the human endometrium. Analysis using monoclonal antibodies to the human progesterone receptor

scientific article published in April 1988

Progesterone receptor isoforms, agonists and antagonists differentially reprogram estrogen signaling.

scientific article published on 28 September 2017

Progesterone receptors in the human heart and great vessels

scientific article published on 01 September 1988

Prolactin activates ERα in the absence of ligand in female mammary development and carcinogenesis in vivo

scientific article published on 24 September 2013

Publisher Correction: Structural underpinnings of oestrogen receptor mutations in endocrine therapy resistance

scientific article published on 01 October 2018

Purification of T47D human progesterone receptor and immunochemical characterization with monoclonal antibodies

scientific article published in August 1988

RAC3 is a pro-migratory co-activator of ERα

scientific article

Rapid Induction of the Unfolded Protein Response and Apoptosis by Estrogen Mimic TTC-352 for the Treatment of Endocrine-Resistant Breast Cancer

scientific article published on 11 November 2020

Receptor interconversion model of hormone action. II. Nucleotide-mediated conversion of estrogen receptors from nonsteroid binding to the lower affinity binding state

scientific article published in December 1986

Receptors Reconsidered: A 20-Year Perspective

scientific article published on January 1, 1982

Recruitment of histone deacetylase 4 to the N-terminal region of estrogen receptor alpha

scientific article

Regulation of estrogen receptor messenger ribonucleic acid and protein levels in human breast cancer cell lines by sex steroid hormones, their antagonists, and growth factors

scientific article published in February 1989

Regulation of progesterone receptor messenger ribonucleic acid and protein levels in MCF-7 cells by estradiol: analysis of estrogen's effect on progesterone receptor synthesis and degradation

scientific article published on 01 March 1988

Relation of estrogen receptor expression to clonal growth and antiestrogen effects on human breast cancer cells.

scientific article published on June 1985

Removal of lactate dehydrogenase-elevating virus from human-in-mouse breast tumor xenografts by cell-sorting ⬇️

scientific article published on February 24, 2011

SUN-006 Lasofoxifene Achieves Potent Anti-Tumor Activity in Hormone-Resistant Breast Tumors by Maintaining High Affinity Binding for Y537S ERα.

scientific article published on 30 April 2019

Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort

scientific article

Selection and characterization of a breast cancer cell line resistant to the antiestrogen LY 117018.

scientific article published on October 1985

Sequence and expression of human estrogen receptor complementary DNA

scientific article

Specific binding of estrogen receptor to the estrogen response element

scientific article published on January 1989

Specific stereochemistry of OP-1074 disrupts estrogen receptor alpha helix 12 and confers pure antiestrogenic activity.

scientific article published on 18 June 2018

Stapled Peptides with γ-Methylated Hydrocarbon Chains for the Estrogen Receptor/Coactivator Interaction

scientific article published on March 2016

Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in <i>ESR1</i> mutant breast cancer cells

scientific article published on 16 May 2022

Structural analysis of covalently labeled estrogen receptors by limited proteolysis and monoclonal antibody reactivity

scientific article published in April 1987

Structural basis for an unexpected mode of SERM-mediated ER antagonism

scientific article published in May 2005

Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism

scientific article

Structural organization and regulation of the chicken estrogen receptor

scientific article

Structural plasticity in the oestrogen receptor ligand-binding domain

scientific article

Structural plasticity in the oestrogen receptor ligand-binding domain.

scientific article published in June 2007

Structural underpinnings of oestrogen receptor mutations in endocrine therapy resistance

scientific article published on 16 April 2018

Structure and dynamics of the estrogen receptor

scientific article

Structure-guided optimization of estrogen receptor binding affinity and antagonist potency of pyrazolopyrimidines with basic side chains.

scientific article published on January 2007

Subcellular distribution of estrogen receptor and progesterone receptor with and without specific ligand

scientific article published in November 1989

The ER-positive/PgR-negative breast cancer phenotype is not associated with mutations within the DNA binding domain

scientific article

The Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Establish a Targetable Pathway in Endocrine Therapy-Resistant Breast Cancer

scientific article published on 01 October 2019

The NFκB pathway promotes tamoxifen tolerance and disease recurrence in estrogen receptor positive breast cancers

scientific article published on 03 April 2020

The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells.

scientific article published on 29 November 2018

The Structure-Function Relationship of Angular Estrogens and Estrogen Receptor Alpha to Initiate Estrogen-Induced Apoptosis in Breast Cancer Cells

scientific article published on 03 May 2020

The effects of 17β-estradiol and a selective estrogen receptor modulator, bazedoxifene, on ovarian carcinogenesis

scientific article published on 11 October 2011

The immunoendocrinology of estrophilin

scientific article published on January 1, 1979

The interaction of human estrogen receptor with DNA is modulated by receptor-associated proteins

scientific article published on 01 October 1994

The limits of the cellular capacity to mediate an estrogen response

scientific article published on February 1992

The progesterone receptor gene maps to human chromosome band 11q13, the site of the mammary oncogene int-2

scientific article

The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen

scientific article

The use of fine needle aspirates in the evaluation of progesterone receptor content in breast cancer

scientific article published in January 1990

The use of monoclonal antibodies to estrogen receptors (ER) for immunoperoxidase detection of ER in paraffin sections of human breast cancer tissue

scientific article published in February 1985

The uterine and vascular actions of estetrol delineate a distinctive profile of estrogen receptor α modulation, uncoupling nuclear and membrane activation

scientific article

Titration by estrogen receptor activation function-2 of targets that are downstream from coactivators

scientific article published on June 1999

Paulina is supported by:

About Paulina

Help