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List of works by George Sgouros

(2S)-2-(3-(1-Carboxy-5-(4-211At-Astatobenzamido)Pentyl)Ureido)-Pentanedioic Acid for PSMA-Targeted α-Particle Radiopharmaceutical Therapy

scientific article published on 26 May 2016

124I PET-based 3D-RD dosimetry for a pediatric thyroid cancer patient: real-time treatment planning and methodologic comparison

scientific article

2-(3-{1-Carboxy-5-[(6-[18F]fluoro-pyridine-3-carbonyl)-amino]-pentyl}-ureido)-pentanedioic acid, [18F]DCFPyL, a PSMA-based PET imaging agent for prostate cancer

scientific article

213Bi (alpha-emitter)-antibody targeting of breast cancer metastases in the neu-N transgenic mouse model

scientific article

32PATP inhibits the growth of xenografted tumors in nude mice ⬇️

scientific article published on May 15, 2012

A Treatment Planning Method for Sequentially Combining Radiopharmaceutical Therapy and External Radiation Therapy ⬇️

scientific article published on October 13, 2010

A bone marrow toxicity model for ²²³Ra alpha-emitter radiopharmaceutical therapy.

scientific article

A gamma camera count rate saturation correction method for whole-body planar imaging

scientific article

A model of cellular dosimetry for macroscopic tumors in radiopharmaceutical therapy ⬇️

scientific article published on June 1, 2011

A nephron-based model of the kidneys for macro-to-micro α-particle dosimetry ⬇️

scientific article published on June 15, 2012

A risk index for pediatric patients undergoing diagnostic imaging with (99m)Tc-dimercaptosuccinic acid that accounts for body habitus

scientific article

Absorbed fractions for alpha-particles in tissues of trabecular bone: considerations of marrow cellularity within the ICRP reference male

scientific article published in July 2005

Alpha-particle emitting atomic generator (Actinium-225)-labeled trastuzumab (herceptin) targeting of breast cancer spheroids: efficacy versus HER2/neu expression

scientific article

Alpha-particles for targeted therapy

scientific article published on 23 April 2008

An Approach for Balancing Diagnostic Image Quality with Cancer Risk: Application to Pediatric Diagnostic Imaging of 99mTc-Dimercaptosuccinic Acid ⬇️

scientific article published on December 1, 2011

An immunotolerant HER-2/neu transgenic mouse model of metastatic breast cancer

scientific article published on October 2008

Antibody association with HER-2/neu-targeted vaccine enhances CD8 T cell responses in mice through Fc-mediated activation of DCs.

scientific article published on May 2008

Antibody-targeted liposomes in cancer therapy and imaging

scientific article published on February 2008

Arterial wall dosimetry for non-Hodgkin lymphoma patients treated with radioimmunotherapy

scientific article

Auger Radiopharmaceutical Therapy Targeting Prostate-Specific Membrane Antigen

scientific article

Binding and interstitial penetration of liposomes within avascular tumor spheroids.

scientific article published in November 2004

Biodistribution, tumor detection, and radiation dosimetry of 18F-DCFBC, a low-molecular-weight inhibitor of prostate-specific membrane antigen, in patients with metastatic prostate cancer

scientific article published on December 2012

Blood and bone marrow dosimetry in radioiodine therapy of thyroid cancer

scientific article published on 01 May 2005

Blood-based red marrow dosimetry: where's the beef?

scientific article published in August 2005

Bone marrow dosimetry using blood-based models for radiolabeled antibody therapy: a multiinstitutional comparison.

scientific article published in October 2004

Bortezomib-induced enzyme-targeted radiation therapy in herpesvirus-associated tumors

scientific article published on 07 September 2008

Calculation of the biological effective dose for piecewise defined dose-rate fits

scientific article published on March 2009

Cancer stem cell targeting using the alpha-particle emitter, 213Bi: mathematical modeling and feasibility analysis

scientific article

Combination treatment with 17-N-allylamino-17-demethoxy geldanamycin and acute irradiation produces supra-additive growth suppression in human prostate carcinoma spheroids.

scientific article published on December 2003

Combined model-based and patient-specific dosimetry for 18F-DCFPyL, a PSMA-targeted PET agent

scientific article published on 19 February 2018

Comparative Dosimetry for 68Ga-DOTATATE: Impact of using Updated ICRP phantoms, S values and Tissue Weighting Factors

scientific article published on 9 February 2018

Comparison of organ residence time estimation methods for radioimmunotherapy dosimetry and treatment planning--patient studies.

scientific article

Correlation of red marrow radiation dosimetry with myelotoxicity: empirical factors influencing the radiation-induced myelotoxicity of radiolabeled antibodies, fragments and peptides in pre-clinical and clinical settings

scientific article published on 01 August 2002

Depth-dependent concentrations of hematopoietic stem cells in the adult skeleton: Implications for active marrow dosimetry.

scientific article

Development and evaluation of convergent and accelerated penalized SPECT image reconstruction methods for improved dose-volume histogram estimation in radiopharmaceutical therapy

scientific article

Dose Estimation in Pediatric Nuclear Medicine

scientific article

Dose-finding study of 153Sm-EDTMP in patients with poor-prognosis osteosarcoma

scientific article

Dosimetry and Radiobiology of Alpha-Particle Emitting Radionuclides

scientific article published on 26 April 2018

Dosimetry for radiopharmaceutical therapy

scientific article

Dosimetry of internal emitters

scientific article

Effective treatment of ductal carcinoma in situ with a HER-2- targeted alpha-particle emitting radionuclide in a preclinical model of human breast cancer

scientific article published on 23 April 2016

Efforts to control the errant products of a targeted in vivo generator

scientific article published in June 2005

Engineered liposomes for potential alpha-particle therapy of metastatic cancer

scientific article published on 01 February 2004

Engineering lipid vesicles of enhanced intratumoral transport capabilities: correlating liposome characteristics with penetration into human prostate tumor spheroids.

scientific article

Enhanced retention of the alpha-particle-emitting daughters of Actinium-225 by liposome carriers

scientific article published on 13 October 2007

Estimates of radiation-absorbed dose to kidneys in patients treated with 90Y-ibritumomab tiuxetan

scientific article

Evaluation of quantitative imaging methods for organ activity and residence time estimation using a population of phantoms having realistic variations in anatomy and uptake

scientific article published on February 2009

Extension of the biological effective dose to the MIRD schema and possible implications in radionuclide therapy dosimetry

scientific article

Fine-Resolution Voxel S Values for Constructing Absorbed Dose Distributions at Variable Voxel Size ⬇️

scientific article published on September 16, 2010

From the Medical Internal Radiation Dose Committee

scientific article published on 01 February 2009

Hematologic toxicity in radioimmunotherapy: dose-response relationships for I-131 labeled antibody therapy

scientific article published on 01 August 2002

Human Biodistribution and Radiation Dosimetry of 82Rb ⬇️

scientific article published on September 16, 2010

Humm recognized with Loevinger-Berman Award.

scientific article published in November 2012

IAEA Support to Medical Physics in Nuclear Medicine ⬇️

scientific article published on May 1, 2013

Imaging of Programmed Cell Death Ligand 1: Impact of Protein Concentration on Distribution of Anti-PD-L1 SPECT Agents in an Immunocompetent Murine Model of Melanoma

scientific article published on 18 May 2017

Immunoliposomal delivery of 213Bi for alpha-emitter targeting of metastatic breast cancer

scientific article

Improved dose–volume histogram estimates for radiopharmaceutical therapy by optimizing quantitative SPECT reconstruction parameters ⬇️

scientific article published on May 7, 2013

Improved tumor imaging and therapy via i.v. IgG-mediated time-sequential modulation of neonatal Fc receptor

scientific article

In vivo multicolor molecular MR imaging using diamagnetic chemical exchange saturation transfer liposomes

scientific article

Indoor air quality assessment in the air traffic control tower of the Athens Airport, Greece

Initial Evaluation of [(18)F]DCFPyL for Prostate-Specific Membrane Antigen (PSMA)-Targeted PET Imaging of Prostate Cancer

scientific article

Internal photon and electron dosimetry of the newborn patient--a hybrid computational phantom study.

scientific article published on March 2012

Introduction to kidney dose-response for radionuclide therapy

scientific article published on 01 June 2004

Kassis receives Loevinger-Berman award ⬇️

scientific article published on December 1, 2010

Koral receives 2011 Loevinger-Berman Award

scientific article published on December 1, 2011

Large anti-HER2/neu liposomes for potential targeted intraperitoneal therapy of micrometastatic cancer

scientific article

Lassmann Recognized with Loevinger-Berman Award

scientific article published in August 2017

Liposome-mediated radiotherapeutics within avascular tumor spheroids: comparative dosimetry study for various radionuclides, liposome systems, and a targeting antibody.

scientific article

Lung dosimetry for radioiodine treatment planning in the case of diffuse lung metastases.

scientific article

Lung toxicity in radioiodine therapy of thyroid carcinoma: development of a dose-rate method and dosimetric implications of the 80-mCi rule

scientific article

MIRD Pamphlet No 19: absorbed fractions and radionuclide S values for six age-dependent multiregion models of the kidney

scientific article published on 01 July 2003

MIRD Pamphlet No. 22 (abridged): radiobiology and dosimetry of alpha-particle emitters for targeted radionuclide therapy.

scientific article published on 15 January 2010

MIRD Pamphlet No. 26: Joint EANM/MIRD Guidelines for Quantitative 177Lu SPECT Applied for Dosimetry of Radiopharmaceutical Therapy

scientific article published on 15 October 2015

MIRD commentary: proposed name for a dosimetry unit applicable to deterministic biological effects--the barendsen (Bd)

scientific article published on 01 March 2009

MIRD continuing education: Bystander and low dose-rate effects: are these relevant to radionuclide therapy?

scientific article published on 14 September 2007

MIRD pamphlet No. 20: the effect of model assumptions on kidney dosimetry and response--implications for radionuclide therapy.

scientific article published on 16 October 2008

MIRD pamphlet No. 21: a generalized schema for radiopharmaceutical dosimetry--standardization of nomenclature

scientific article

MIRD pamphlet No. 23: quantitative SPECT for patient-specific 3-dimensional dosimetry in internal radionuclide therapy

scientific article

MIRD pamphlet No. 24: Guidelines for quantitative 131I SPECT in dosimetry applications

scientific article published on 15 October 2013

Mitigation of radiation nephropathy after internal alpha-particle irradiation of kidneys

scientific article published on 28 February 2006

Modelling and Dosimetry for Alpha-Particle Therapy ⬇️

scientific article published on July 1, 2011

Murine S factors for liver, spleen, and kidney.

scientific article published in May 2003

N-[N-[(S)-1,3-Dicarboxypropyl]carbamoyl]-4-[18F]fluorobenzyl-L-cysteine, [18F]DCFBC: a new imaging probe for prostate cancer

scientific article published on May 2008

O'Donoghue Recognized with Loevinger-Berman Award

scientific article published in August 2016

Patient-specific dosimetry for 131I thyroid cancer therapy using 124I PET and 3-dimensional-internal dosimetry (3D-ID) software

scientific article published on 01 August 2004

Patient-specific, 3-dimensional dosimetry in non-Hodgkin's lymphoma patients treated with 131I-anti-B1 antibody: assessment of tumor dose-response

scientific article published in February 2003

Pharmacokinetic modeling of [(18)F]fluorodeoxyglucose (FDG) for premature infants, and newborns through 5-year-olds

scientific article published on 17 March 2016

Pharmacokinetics and Biodistribution of (86)Y-Trastuzumab for (90)Y dosimetry in an ovarian carcinoma model: correlative MicroPET and MRI.

scientific article published in July 2003

Pharmacokinetics, dosimetry, and toxicity of the targetable atomic generator, 225Ac-HuM195, in nonhuman primates

scientific article

Pharmacokinetics, microscale distribution, and dosimetry of alpha-emitter-labeled anti-PD-L1 antibodies in an immune competent transgenic breast cancer model

scientific article published on 18 July 2017

Pre-therapeutic (124)I PET(/CT) dosimetry confirms low average absorbed doses per administered (131)I activity to the salivary glands in radioiodine therapy of differentiated thyroid cancer

scientific article

Preclinical evaluation of 86Y-labeled inhibitors of prostate-specific membrane antigen for dosimetry estimates

scientific article published on 26 February 2015

Predicting hematologic toxicity in patients undergoing radioimmunotherapy with 90Y-ibritumomab tiuxetan or 131I-tositumomab ⬇️

scientific article published on December 1, 2010

Quantitative impact of changes in marrow cellularity, skeletal size, and bone mineral density on active marrow dosimetry based upon a reference model.

scientific article published in January 2017

Radiation Dosimetry of 82Rb in Humans Under Pharmacologic Stress ⬇️

scientific article published on February 14, 2011

Radiobiologic Optimization of Combination Radiopharmaceutical Therapy Applied to Myeloablative Treatment of Non-Hodgkin Lymphoma ⬇️

scientific article published on August 5, 2013

Radioimmunotherapy of Solid Tumors: Searching for the Right Target ⬇️

scientific article published on January 1, 2011

Radioimmunotherapy of breast cancer metastases with alpha-particle emitter 225Ac: comparing efficacy with 213Bi and 90Y.

scientific article

Radiopharmaceutical therapy in the era of precision medicine

scientific article

Rationales, evidence, and design considerations for fractionated radioimmunotherapy

scientific article published in February 2002

Recombinant Human Thyroid-Stimulating Hormone Versus Thyroid Hormone Withdrawal in 124I PET/CT-Based Dosimetry for 131I Therapy of Metastatic Differentiated Thyroid Cancer

scientific article published on 19 January 2017

Redefining Relative Biological Effectiveness in the Context of the EQDX Formalism: Implications for Alpha-Particle Emitter Therapy

scientific article

Redefining relative biological effectiveness in the context of the EQDX formalism: implications for alpha-particle emitter therapy

scientific article published on January 2014

Renal Dosimetry ⬇️

scientific article published on September 28, 2010

Renal tubulointerstitial changes after internal irradiation with alpha-particle-emitting actinium daughters

scientific article published on 29 June 2005

Sequential cytarabine and alpha-particle immunotherapy with bismuth-213-lintuzumab (HuM195) for acute myeloid leukemia

scientific article

Short-term and low-dose oral fluconazole treatment can cause Stevens-Johnson syndrome in HIV-negative patients

scientific article published on 01 December 2011

Size-induced enhancement of chemical exchange saturation transfer (CEST) contrast in liposomes

scientific article

Spheroids of Prostate Tumor Cell Lines

scientific article published on 01 January 2003

Strengths and Weaknesses of a Planar Whole-Body Method of (153)Sm Dosimetry for Patients with Metastatic Osteosarcoma and Comparison with Three-Dimensional Dosimetry

scientific article

Tandem dosing of samarium-153 ethylenediamine tetramethylene phosphoric acid with stem cell support for patients with high-risk osteosarcoma

scientific article

Targeted alpha particle immunotherapy for myeloid leukemia

scientific article published on 01 August 2002

Targeted and Nontargeted α-Particle Therapies

scientific article published on 18 January 2018

Targeting Aberrant DNA Double-Strand Break Repair in Triple-Negative Breast Cancer with Alpha-Particle Emitter Radiolabeled Anti-EGFR Antibody ⬇️

scientific article published on July 19, 2013

The role of preclinical models in radiopharmaceutical therapy

scientific article published on January 2014

Therapeutic potential of 90Y- and 131I-labeled anti-CD20 monoclonal antibody in treating non-Hodgkin's lymphoma with pulmonary involvement: a Monte Carlo-based dosimetric analysis.

scientific article

Three-dimensional imaging-based radiobiological dosimetry

scientific article published on September 2008

Three-dimensional radiobiologic dosimetry: application of radiobiologic modeling to patient-specific 3-dimensional imaging-based internal dosimetry

scientific article published on 15 May 2007

Three-dimensional radiobiological dosimetry (3D-RD) with 124I PET for 131I therapy of thyroid cancer ⬇️

scientific article published on April 12, 2011

Three‐dimensional radiobiological dosimetry of kidneys for treatment planning in peptide receptor radionuclide therapy ⬇️

scientific article published on October 1, 2012

Toward patient-friendly cell-level dosimetry

scientific article published on 01 April 2007

Trafficking of high avidity HER-2/neu-specific T cells into HER-2/neu-expressing tumors after depletion of effector/memory-like regulatory T cells

scientific article (publication date: 2012)

Tumor Dosimetry and Response for 153Sm-Ethylenediamine Tetramethylene Phosphonic Acid Therapy of High-Risk Osteosarcoma ⬇️

scientific article published on January 17, 2012

Tumor and red bone marrow dosimetry: comparison of methods for prospective treatment planning in pretargeted radioimmunotherapy

scientific article

Update: molecular radiotherapy: survey and current status

scientific article published on October 2008

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