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List of works by Kate E. Broderick

A DNA vaccine delivered by dermal electroporation fully protects cynomolgus macaques against Lassa fever

scientific article published on 18 October 2017

A Synthetic Micro-Consensus DNA Vaccine Generates Comprehensive Influenza A H3N2 Immunity and Protects Mice Against Lethal Challenge by Multiple H3N2 Viruses

scholarly article by Sarah T C Elliott published in September 2018

A heterologous prime/boost vaccination strategy enhances the immunogenicity of therapeutic vaccines for hepatitis C virus.

scientific article published on 17 June 2013

A multi-head intradermal electroporation device allows for tailored and increased dose DNA vaccine delivery to the skin

scientific article

A multi-head intradermal electroporation device allows for tailored and increased dose DNA vaccine delivery to the skin.

scientific article published in January 2015

A novel prototype device for electroporation-enhanced DNA vaccine delivery simultaneously to both skin and muscle.

scientific article published in January 2011

A synthetic codon-optimized hepatitis C virus nonstructural 5A DNA vaccine primes polyfunctional CD8+ T cell responses in wild-type and NS5A-transgenic mice

scientific article published on 2 January 2013

Active Immunoprophylaxis and Vaccine Augmentations Mediated by a Novel Plasmid DNA Formulation

Adjuvanted multi-epitope vaccines protect HLA-A*11:01 transgenic mice against Toxoplasma gondii

scientific article published on 22 September 2016

Altered response hierarchy and increased T-cell breadth upon HIV-1 conserved element DNA vaccination in macaques

scientific article

Augmentation of cellular and humoral immune responses to HPV16 and HPV18 E6 and E7 antigens by VGX-3100

scientific article published on 30 November 2016

Broad cross-protective anti-hemagglutination responses elicited by influenza microconsensus DNA vaccine

scientific article published on 31 October 2017

Characterization of guinea pig T cell responses elicited after EP-assisted delivery of DNA vaccines to the skin

scientific article

Clinical development of intramuscular electroporation: providing a "boost" for DNA vaccines

scientific article published on January 2014

Comparison of immune responses generated by optimized DNA vaccination against SIV antigens in mice and macaques

scientific article

Comparison of intradermal and intramuscular delivery followed by in vivo electroporation of SIV Env DNA in macaques.

scientific article published on 28 June 2013

Control of Heterologous Simian Immunodeficiency Virus SIV Infection by DNA and Protein Coimmunization Regimens Combined with Different Toll-Like-Receptor-4-Based Adjuvants in Macaques

scientific article published on 17 July 2018

Cyanide detoxification by the cobalamin precursor cobinamide

scientific article

Cyanide produced by human isolates of Pseudomonas aeruginosa contributes to lethality in Drosophila melanogaster

scientific article published in February 2008

DNA Vaccine-Induced Long-Lasting Cytotoxic T Cells Targeting Conserved Elements of Human Immunodeficiency Virus Gag Are Boosted Upon DNA or Recombinant Modified Vaccinia Ankara Vaccination

scholarly article by Xintao Hu published in September 2018

DNA and virus particle vaccination protects against acquisition and confers control of viremia upon heterologous simian immunodeficiency virus challenge

scientific article published on 28 January 2013

DNA vaccination in skin enhanced by electroporation

scientific article published in January 2014

DNA vaccination strategy targets epidermal dendritic cells, initiating their migration and induction of a host immune response.

scientific article published on 3 December 2014

DNA vaccine VGX-3100 with electroporation induces regression of cervical intraepithelial neoplasia 2/3 and clears HPV infection with robust T cell responses: results of a randomized, double-blind, placebo-controlled Phase II trial

article

DNA vaccines elicit durable protective immunity against individual or simultaneous infections with Lassa and Ebola viruses in guinea pigs

scientific article published on 14 November 2017

DNA-based influenza vaccines: evaluating their potential to provide universal protection

scientific article published on October 1, 2010

Development of an intradermal DNA vaccine delivery strategy to achieve single-dose immunity against respiratory syncytial virus

scientific article published on 13 April 2017

Direct transfection of dendritic cells in the epidermis after plasmid delivery enhanced by surface electroporation.

scientific article

Ectopic expression of bovine type 5 phosphodiesterase confers a renal phenotype in Drosophila.

scientific article published on 8 December 2003

Electroporation mediated DNA vaccination directly to a mucosal surface results in improved immune responses

scientific article published on 11 June 2013

Electroporation of plasmid DNA to swine muscle

scientific article published in January 2011

Electroporation-enhanced delivery of nucleic acid vaccines

scientific article published on 09 December 2014

Elucidating the Kinetics of Expression and Immune Cell Infiltration Resulting from Plasmid Gene Delivery Enhanced by Surface Dermal Electroporation

scientific article published on 28 August 2013

Enhanced Delivery and Potency of Self-Amplifying mRNA Vaccines by Electroporation in Situ

scientific article published on 22 August 2013

Enhanced Delivery of DNA or RNA Vaccines by Electroporation

scientific article

Enhanced Efficacy of a Codon-Optimized DNA Vaccine Encoding the Glycoprotein Precursor Gene of Lassa Virus in a Guinea Pig Disease Model When Delivered by Dermal Electroporation.

scientific article published on 18 July 2013

Gag and env conserved element CE DNA vaccines elicit broad cytotoxic T cell responses targeting subdominant epitopes of HIV and SIV Able to recognize virus-infected cells in macaques

article

Guanosine 3',5'-cyclic monophosphate (cGMP)/cGMP-dependent protein kinase induce interleukin-6 transcription in osteoblasts

scientific article

HIV Env conserved element DNA vaccine alters immunodominance in macaques

scientific article published on 5 July 2017

HIV-1 Env DNA vaccine plus protein boost delivered by EP expands B- and T-cell responses and neutralizing phenotype in vivo

scientific article

HIV-1 p24(gag) derived conserved element DNA vaccine increases the breadth of immune response in mice

scientific article

IL-12 DNA as molecular vaccine adjuvant increases the cytotoxic T cell responses and breadth of humoral immune responses in SIV DNA vaccinated macaques

scientific article published on 16 August 2012

Immunogenicity of a DNA vaccine candidate for COVID-19

scientific article published on 20 May 2020

Immunotherapy against HPV16/18 generates potent TH1 and cytotoxic cellular immune responses

scientific article

In vivo protection against ZIKV infection and pathogenesis through passive antibody transfer and active immunisation with a prMEnv DNA vaccine

scientific article

Influenza A vaccines using linear expression cassettes delivered via electroporation afford full protection against challenge in a mouse model ⬇️

scientific article published on March 8, 2012

Interactions between epithelial nitric oxide signaling and phosphodiesterase activity in Drosophila.

scientific article published on 9 July 2003

Intradermal DNA vaccination enhanced by low-current electroporation improves antigen expression and induces robust cellular and humoral immune responses.

scientific article

Intradermal SynCon® Ebola GP DNA Vaccine is Temperature Stable and Safely Demonstrates Cellular and Humoral Immunogenicity Advantages in Healthy Volunteers

scientific article published on 01 July 2019

Microneedles 2012.

scientific article published in August 2012

Nitric oxide scavenging by the cobalamin precursor cobinamide.

scientific article

Nitrosyl-cobinamide, a new and direct nitric oxide releasing drug effective in vivo.

scientific article

Nucleic acid-based vaccines targeting respiratory syncytial virus: delivering the goods

scientific article published on 7 September 2017

Optimization of electroporation-enhanced intradermal delivery of DNA vaccine using a minimally invasive surface device

scientific article

Optimized in vivo transfer of small interfering RNA targeting dermal tissue using in vivo surface electroporation.

scientific article

Piezoelectric permeabilization of mammalian dermal tissue for in vivo DNA delivery leads to enhanced protein expression and increased immunogenicity.

scientific article published in January 2011

Protection against dengue disease by synthetic nucleic acid antibody prophylaxis/immunotherapy

scientific article published on 29 July 2015

Protective Efficacy and Long-Term Immunogenicity in Cynomolgus Macaques by Ebola Virus Glycoprotein Synthetic DNA Vaccines

scientific article published on 01 January 2019

Rapid development of a synthetic DNA vaccine for COVID-19

article

Role of cyclic GMP in gene regulation

scientific article

Safety, efficacy, and immunogenicity of VGX-3100, a therapeutic synthetic DNA vaccine targeting human papillomavirus 16 and 18 E6 and E7 proteins for cervical intraepithelial neoplasia 2/3: a randomised, double-blind, placebo-controlled phase 2b tri

scientific article published on 16 September 2015

Skin Transfection Patterns and Expression Kinetics of Electroporation-Enhanced Plasmid Delivery Using the CELLECTRA-3P, a Portable Next-Generation Dermal Electroporation Device

scientific article published on 29 July 2015

Synthetic DNA-encoded monoclonal antibody delivery of anti-CTLA-4 antibodies induces tumor shrinkage in vivo

scientific article published on 04 October 2018

The Dh gene of Drosophila melanogaster encodes a diuretic peptide that acts through cyclic AMP.

scientific article published in December 2002

The cobalamin precursor cobinamide detoxifies nitroprusside-generated cyanide.

scientific article published in June 2007

The dg2 (for) gene confers a renal phenotype in Drosophila by modulation of cGMP-specific phosphodiesterase.

scientific article published in July 2004

The nitric oxide scavenger cobinamide profoundly improves survival in a Drosophila melanogaster model of bacterial sepsis

scientific article published in September 2006

The p40 subunit of interleukin (IL)-12 promotes stabilization and export of the p35 subunit: implications for improved IL-12 cytokine production.

scientific article published on 7 January 2013

Transient receptor potential-like channels are essential for calcium signaling and fluid transport in a Drosophila epithelium

scientific article

Two nitridergic peptides are encoded by the gene capability in Drosophila melanogaster.

scientific article published on May 2002

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