List of works by James Wheeler

(MIS)Use of the Adverse Outcome Pathway Concept for Assessing Endocrine Disruption in Nontarget Organisms

scientific article published on 01 June 2020

A Decision Logic for the Reliability Assessment and Interpretation of Vitellogenin Measurements

scientific article published on 9 July 2024

A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment

scientific article

A critical review of histopathological findings associated with endocrine and non-endocrine hepatic toxicity in fish models

scientific article published on 12 February 2018

A method to predict and understand fish survival under dynamic chemical stress using standard ecotoxicity data

scientific article

A review of the evidence for endocrine disrupting effects of current-use chemicals on wildlife populations

scientific article published on 24 November 2017

Acute oral toxicity of chemicals in terrestrial life stages of amphibians: Comparisons to birds and mammals

scientific article

Advancing the assessment of population stability as a protection goal in ecotoxicology.

scientific article published in January 2018

An evaluation of fish early life stage tests for predicting reproductive and longer-term toxicity from plant protection product active substances

scientific article published on 27 June 2014

Application of the threshold approach for acute fish toxicity testing to plant protection products: a proposed framework

scientific article published on 30 October 2013

Are acute and chronic saltwater fish studies required for plant protection and biocidal product active substance risk assessment?

scientific article published on 21 January 2014

Assessing the population relevance of endocrine-disrupting effects for nontarget vertebrates exposed to plant protection products

scientific article published on 30 January 2019

Better bootstrap estimation of hazardous concentration thresholds for aquatic assemblages

scientific article published in July 2002

Building and Applying Quantitative Adverse Outcome Pathway Models for Chemical Hazard and Risk Assessment

scientific article published on 08 August 2019

Comparative acute and chronic sensitivity of fish and amphibians: a critical review of data

scientific article

Critical Review of Read-Across Potential in Testing for Endocrine-Related Effects in Vertebrate Ecological Receptors

scientific article published on 04 March 2020

Density-dependent processes in the life history of fishes: evidence from laboratory populations of zebrafish Danio rerio

scientific article (publication date: 2012)

Distinguishing between endocrine disruption and non-specific effects on endocrine systems

scientific article published on 12 September 2018

Endocrine Disruption: Current approaches for regulatory testing and assessment of plant protection products are fit for purpose

article

Establishing the relevance of endocrine-disrupting effects for nontarget vertebrate populations

scientific article published on 01 March 2019

Freshwater to saltwater toxicity extrapolation using species sensitivity distributions

article

Freshwater to saltwater toxicity extrapolation using species sensitivity distributions

scientific article published on 01 November 2002

Hormone data collection in support of endocrine disruption (ED) assessment for aquatic vertebrates: Pragmatic and animal welfare considerations

scientific article published on 01 December 2020

How the Xenopus eleutheroembryonic thyroid assay compares to the amphibian metamorphosis assay for detecting thyroid active chemicals

scientific article published in May 2024

Improving environmental risk assessments of chemicals: Steps towards evidence-based ecotoxicology

scientific article published on 03 May 2019

In Response: Adverse outcome pathways--An industry perspective

scientific article published on 01 September 2015

Integrating ecosystem services into crop protection and pest management: Case study with the soil fumigant 1,3-dichloropropene and its use in tomato production in Italy.

scientific article

Interpretation of sexual secondary characteristics (SSCs) in regulatory testing for endocrine activity in fish

scientific article published on 24 September 2019

Key Opportunities to Replace, Reduce and Refine Regulatory Fish Acute Toxicity Tests

scientific article published on 18 July 2020

Mind the gap: Concerns using endpoints from endocrine screening assays in risk assessment

scientific article published on 2 June 2014

Mode of sexual differentiation and its influence on the relative sensitivity of the fathead minnow and zebrafish in the fish sexual development test

scientific article published on 23 July 2011

Multi-criteria decision analysis of test endpoints for detecting the effects of endocrine active substances in fish full life cycle tests.

scientific article published in July 2010

Population relevance of toxicant mediated changes in sex ratio in fish: An assessment using an individual-based zebrafish (Danio rerio) model

article

Promoting the 3Rs to enhance the OECD fish toxicity testing framework

scientific article published on 9 February 2016

Recommended approaches to the scientific evaluation of ecotoxicological hazards and risks of endocrine-active substances.

scientific article

Reducing repetition of regulatory vertebrate ecotoxicology studies

scientific article published in September 2017

Reducing the number of fish in bioconcentration studies for plant protection products by reducing the number of test concentrations

scientific article published on 2 October 2012

Reducing the number of fish in bioconcentration studies with general chemicals by reducing the number of test concentrations

scientific article published on 14 August 2014

Reducing the number of fish in regulatory bioconcentration testing: Identifying and overcoming the barriers to using the 1-concentration approach

scientific article published on 01 January 2017

Refinement of the ECETOC approach to identify endocrine disrupting properties of chemicals in ecotoxicology.

scientific article published on 4 March 2013

Risk assessment of endocrine active chemicals: identifying chemicals of regulatory concern

scientific article published on 23 June 2012

Saving two birds with one stone: using active substance avian acute toxicity data to predict formulated plant protection product toxicity

scientific article

Science based guidance for the assessment of endocrine disrupting properties of chemicals.

scientific article published on 19 September 2010

Species extrapolation for the 21st century.

scientific article published in January 2011

Test concentration setting for fish in vivo endocrine screening assays

scientific article published on 05 March 2013

The chironomid acute toxicity test: development of a new test system

scientific article published in April 2010

The use of carrier solvents in regulatory aquatic toxicology testing: practical, statistical and regulatory considerations

scientific article published on 17 October 2013

The utility of QSARs in predicting acute fish toxicity of pesticide metabolites: A retrospective validation approach

scientific article

Thresholds of toxicological concern for endocrine active substances in the aquatic environment

scientific article published on January 2010

Uncertainties in biological responses that influence hazard and risk approaches to the regulation of endocrine active substances.

scientific article published on 11 November 2016

Vitellogenin: a review of analytical methods to detect (anti) estrogenic activity in fish.

scientific article published on January 2005

Weight of evidence approaches for the identification of endocrine disrupting properties of chemicals: Review and recommendations for EU regulatory application

scientific article published on 4 October 2017

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