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List of works by Leslie J Baier

A Genome-Wide Association Study Using a Custom Genotyping Array Identifies Variants in GPR158 Associated With Reduced Energy Expenditure in American Indians

scientific article published on 5 May 2017

A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants

scientific article published on 10 May 2017

A Gly482Ser missense mutation in the peroxisome proliferator-activated receptor gamma coactivator-1 is associated with altered lipid oxidation and early insulin secretion in Pima Indians

scientific article published in March 2003

A Loss-Of-Function Splice Acceptor Variant in IGF2 is Protective for Type 2 Diabetes

scientific article

A Search for Variants Associated With Young-Onset Type 2 Diabetes in American Indians in a 100K Genotyping Array

scientific article published on 10 September 2007

A cis-eQTL in PFKFB2 is associated with diabetic nephropathy, adiposity and insulin secretion in American Indians

scientific article published on 6 February 2015

A functional ABCA1 gene variant is associated with low HDL-cholesterol levels and shows evidence of positive selection in Native Americans.

scientific article

A functional Tyr1306Cys variant in LARG is associated with increased insulin action in vivo

scientific article published on May 2006

A functional variant in the peroxisome proliferator-activated receptor gamma2 promoter is associated with predictors of obesity and type 2 diabetes in Pima Indians

scientific article published on July 2003

A genome-wide association study in American Indians implicates DNER as a susceptibility locus for type 2 diabetes

scientific journal article

A genome-wide association study of BMI in American Indians

scientific article published on 23 June 2011

A novel missense substitution (Val1483Ile) in the fatty acid synthase gene (FAS) is associated with percentage of body fat and substrate oxidation rates in nondiabetic Pima Indians

scientific article

ABCC8 R1420H Loss-of-Function Variant in a Southwest American Indian Community: Association With Increased Birth Weight and Doubled Risk of Type 2 Diabetes

scientific article

Activating transcription factor 6 (ATF6) sequence polymorphisms in type 2 diabetes and pre-diabetic traits

scientific article published on March 2007

Admixture Mapping Identifies an Amerindian Ancestry Locus Associated with Albuminuria in Hispanics in the United States

scientific article published on 30 January 2017

Admixture mapping in the Hispanic Community Health Study/Study of Latinos reveals regions of genetic associations with blood pressure traits

scientific article published on 20 November 2017

An ACACB variant implicated in diabetic nephropathy associates with body mass index and gene expression in obese subjects

scientific article

Analysis of SLC16A11 Variants in 12,811 American Indians: Genotype-Obesity Interaction for Type 2 Diabetes and an Association With RNASEK Expression

scientific article published on 20 October 2015

Analysis of the SIM1 contribution to polygenic obesity in the French population

scientific article

Assessing FOXO1A as a potential susceptibility locus for type 2 diabetes and obesity in American Indians

scientific article

Assessing accuracy of genotype imputation in American Indians

scientific article

Assessing variation across 8 established East Asian loci for type 2 diabetes mellitus in American Indians: Suggestive evidence for new sex-specific diabetes signals in GLIS3 and ZFAND3.

scientific article published on 8 November 2016

Assessment of established HDL-C loci for association with HDL-C levels and type 2 diabetes in Pima Indians

scientific article published on 15 December 2015

Association analyses of variants in the DIO2 gene with early-onset type 2 diabetes mellitus in Pima Indians

scientific article published on 5 December 2011

Association analysis of Krüppel-like factor 11 variants with type 2 diabetes in Pima Indians

scientific article published on July 2008

Association analysis of variation in/near FTO, CDKAL1, SLC30A8, HHEX, EXT2, IGF2BP2, LOC387761, and CDKN2B with type 2 diabetes and related quantitative traits in Pima Indians

scientific article

Bimodal distribution of RNA expression levels in human skeletal muscle tissue

scientific article

CHRM3 gene variation is associated with decreased acute insulin secretion and increased risk for early-onset type 2 diabetes in Pima Indians.

scientific article

Common genetic variation in and near the melanocortin 4 receptor gene (MC4R) is associated with body mass index in American Indian adults and children

scientific article

Common genetic variation in the glucokinase gene (GCK) is associated with type 2 diabetes and rates of carbohydrate oxidation and energy expenditure

scientific article

Common variation in SIM1 is reproducibly associated with BMI in Pima Indians

scientific article published on 28 April 2009

Differential expression of matrix metalloproteinase 3 (MMP3) in preadipocytes/stromal vascular cells from nonobese nondiabetic versus obese nondiabetic Pima Indians.

scientific article

Differential methylation of genes in individuals exposed to maternal diabetes in utero

scientific article published on 26 January 2017

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

scientific article

Evaluation of A2BP1 as an obesity gene ⬇️

scientific article

Evidence for a Role of LPGAT1 in Influencing BMI and Percent Body Fat in Native Americans

scholarly article by Michael T. Traurig et al published 22 June 2012 in Obesity

Evidence for a role of LPGAT1 in influencing BMI and percent body fat in Native Americans

scientific article published on January 2013

Evidence that Rho guanine nucleotide exchange factor 11 (ARHGEF11) on 1q21 is a type 2 diabetes susceptibility gene in the Old Order Amish.

scientific article published on 16 March 2007

Functional and association analysis of an Amerindian-derived population-specific p.(Thr280Met) variant in RBPJL, a component of the PTF1 complex

scientific article published on 4 January 2018

Functional variants in MBL2 are associated with type 2 diabetes and pre-diabetes traits in Pima Indians and the old order Amish

scientific article

Gene for susceptibility to diabetic nephropathy in type 2 diabetes maps to 18q22.3-23

article

Genetic studies of the etiology of type 2 diabetes in Pima Indians: hunting for pieces to a complicated puzzle

scientific article

Genetic variation in the human winged helix/forkhead transcription factor gene FOXC2 in Pima Indians

scientific article

Genome-wide Association Study of Platelet Count Identifies Ancestry-Specific Loci in Hispanic/Latino Americans

scientific article

Greater impact of melanocortin-4 receptor deficiency on rates of growth and risk of type 2 diabetes during childhood compared with adulthood in Pima Indians

scientific article published on 21 November 2011

Hyperphagia: current concepts and future directions proceedings of the 2nd international conference on hyperphagia

scientific article

Identification and functional analysis of a novel G310D variant in the insulin-like growth factor 1 receptor (IGF1R) gene associated with type 2 diabetes in American Indians

scientific article published on 22 February 2018

Identification of genetic variation that determines human trehalase activity and its association with type 2 diabetes

scientific article published on 7 March 2013

Identification of susceptibility genes for complex metabolic diseases.

scientific article

Identity-by-Descent Mapping Identifies Major Locus for Serum Triglycerides in Amerindians Largely Explained by an APOC3 Founder Mutation

scientific article

Involvement of the chemokine-like receptor GPR33 in innate immunity

scientific article

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

scientific article

Linkage disequilibrium mapping of the replicated type 2 diabetes linkage signal on chromosome 1q

scientific article (publication date: July 2009)

Lower metabolic rate in individuals heterozygous for either a frameshift or a functional missense MC4R variant

scientific article published on 03 October 2008

MAP2K3 is associated with body mass index in American Indians and Caucasians and may mediate hypothalamic inflammation

scientific article published on 03 July 2013

Melanocortin 4 receptor gene variation is associated with severe obesity in Pima Indians

scientific article published on 01 October 2004

Metabolic effects of the Gly1057Asp polymorphism in IRS-2 and interactions with obesity

scientific article published in June 2003

PCLO variants are nominally associated with early-onset type 2 diabetes and insulin resistance in Pima Indians

scientific article published on 22 July 2008

Polymorphisms in the oxygen-regulated protein 150 gene (ORP150) are associated with insulin resistance in Pima Indians.

scientific article

Positional cloning of an obesity/diabetes susceptibility gene(s) on chromosome 11 in Pima Indians

scientific article published on 01 June 2002

Potential epigenetic dysregulation of genes associated with MODY and type 2 diabetes in humans exposed to a diabetic intrauterine environment: an analysis of genome-wide DNA methylation

scientific article published on 21 January 2014

Role of Established Type 2 Diabetes-Susceptibility Genetic Variants in a High Prevalence American Indian Population

scientific article published on 9 February 2015

SIRT1 is associated with a decrease in acute insulin secretion and a sex specific increase in risk for type 2 diabetes in Pima Indians

scientific article published on 7 August 2011

Strong parent-of-origin effects in the association of KCNQ1 variants with type 2 diabetes in American Indians

scientific article published on 29 April 2013

TCF7L2 is not a major susceptibility gene for type 2 diabetes in Pima Indians: analysis of 3,501 individuals

scientific article

The Gly482Ser genotype at the PPARGC1A gene and elevated blood pressure: a meta-analysis involving 13,949 individuals

scientific article published on 08 May 2008

The effect of differing patterns of childhood body mass index gain on adult physiology in American Indians.

scientific article

The insulin gene variable number tandem repeat class I/III polymorphism is in linkage disequilibrium with birth weight but not Type 2 diabetes in the Pima population

scientific article published in January 2003

The role of insulin receptor substrate-1 gene (IRS1) in type 2 diabetes in Pima Indians

scientific article published in December 2003

Variants associated with type 2 diabetes identified by the transethnic meta-analysis study: assessment in American Indians and evidence for a new signal in LPP.

scientific article

Variants in ARHGEF11, a candidate gene for the linkage to type 2 diabetes on chromosome 1q, are nominally associated with insulin resistance and type 2 diabetes in Pima Indians

scientific article

Variants in ASK1 are associated with skeletal muscle ASK1 expression, in vivo insulin resistance, and type 2 diabetes in Pima Indians

scientific article

Variants in hepatocyte nuclear factor 4alpha are modestly associated with type 2 diabetes in Pima Indians.

scientific article

Variants in the Ca V 2.3 (alpha 1E) subunit of voltage-activated Ca2+ channels are associated with insulin resistance and type 2 diabetes in Pima Indians

scientific article (publication date: December 2007)

Variants in the LEPR gene are nominally associated with higher BMI and lower 24-h energy expenditure in Pima Indians

scientific article

Variation Within the Gene Encoding the Upstream Stimulatory Factor 1 Does Not Influence Susceptibility to Type 2 Diabetes in Samples From Populations With Replicated Evidence of Linkage to Chromosome 1q

article

Variations in peptide YY and Y2 receptor genes are associated with severe obesity in Pima Indian men.

scientific article

Whole exome sequencing identifies variation in CYB5A and RNF10 associated with adiposity and type 2 diabetes.

scientific article published on 05 December 2013

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