List of works - Christophe Desterke

A cross-talk between stromal cell-derived factor-1 and transforming growth factor-beta controls the quiescence/cycling switch of CD34(+) progenitors through FoxO3 and mammalian target of rapamycin

scientific article

Assessment of sites of marrow and extramedullary hematopoiesis by hybrid imaging in primary myelofibrosis patients

scientific article published on 12 August 2016

Bone morphogenetic protein antagonist gene NOG is involved in myeloproliferative disease associated with myelofibrosis

scientific article

CAGE profiling of ncRNAs in hepatocellular carcinoma reveals widespread activation of retroviral LTR promoters in virus-induced tumors.

scientific article

CXCR4/CXCL12 axis counteracts hematopoietic stem cell exhaustion through selective protection against oxidative stress

scientific article published on 25 November 2016

CXCR7 participates in CXCL12-induced CD34+ cell cycling through β-arrestin-dependent Akt activation.

scientific article published on 25 November 2013

Cannabinoid receptor 1 is a major mediator of renal fibrosis.

scientific article published on 11 March 2015

Differentiation between isolates of Aspergillus fumigatus from breeding turkeys and their environment by genotyping with microsatellite markers

scientific article

Dual SP/ALDH functionalities refine the human hematopoietic Lin-CD34+CD38- stem/progenitor cell compartment.

scientific article

Effect of Allogeneic Oral Mucosa Mesenchymal Stromal Cells on Equine Wound Repair

scientific article published on 14 December 2021

Effects in Cancer Cells of the Recombinant l-Methionine Gamma-Lyase from Brevibacterium aurantiacum. Encapsulation in Human Erythrocytes for Sustained l-Methionine Elimination

scientific article published on 02 April 2019

Embryonic Program Activated during Blast Crisis of Chronic Myelogenous Leukemia (CML) Implicates a TCF7L2 and MYC Cooperative Chromatin Binding

scientific article published on 05 June 2020

Enteric Delivery of Regenerating Family Member 3 alpha Alters the Intestinal Microbiota and Controls Inflammation in Mice With Colitis

scientific article

Experimental and integrative analyses identify an ETS1 network downstream BCR-ABL in chronic myeloid leukemia (CML).

scientific article published on 4 May 2018

Expression level and differential JAK2-V617F-binding of the adaptor protein Lnk regulates JAK2-mediated signals in myeloproliferative neoplasms

scientific article

Expression of HMGA2 in PB leukocytes and purified CD34+ cells from controls and patients with Myelofibrosis and myeloid metaplasia

scientific article published on 01 September 2006

FLT3-mediated p38-MAPK activation participates in the control of megakaryopoiesis in primary myelofibrosis.

scientific article

Gamma-smooth muscle actin expression is associated with epithelial-mesenchymal transition and stem-like properties in hepatocellular carcinoma

scientific article published on 25 June 2015

Genomic landscape analyses of reprogrammed cells using integrative and non-integrative methods reveal variable cancer-associated alterations

Global MicroRNA Profiling Uncovers miR-206 as a Negative Regulator of Hematopoietic Commitment in Human Pluripotent Stem Cells ⬇️

scientific article published on 08 April 2019

Hepatic and serum lipid signatures specific to nonalcoholic steatohepatitis in murine models

scientific article published on 11 August 2016

Hepatitis B virus pregenomic RNA in hepatocellular carcinoma: A nosological and prognostic determinant

scientific article published on 12 August 2017

Hepatitis C virus core protein targets 4E-BP1 expression and phosphorylation and potentiates Myc-induced liver carcinogenesis in transgenic mice

scientific article published on 20 April 2017

IL-8 and its CXCR1 and CXCR2 receptors participate in the control of megakaryocytic proliferation, differentiation, and ploidy in myeloid metaplasia with myelofibrosis

scientific article published on 28 September 2004

Inflammation as a Keystone of Bone Marrow Stroma Alterations in Primary Myelofibrosis

scientific article

Metabolism dysregulation induces a specific lipid signature of nonalcoholic steatohepatitis in patients

scientific article

Molecular Diversity and Routes of Colonization ofCandida albicansin a Surgical Intensive Care Unit, as Studied Using Microsatellite Markers

scientific article published in 2002

Osteogenic Potential of Mesenchymal Stromal Cells Contributes to Primary Myelofibrosis

scientific article published on 24 September 2015

Pharmacogenetic determinants of outcomes on triplet hepatic artery infusion and intravenous cetuximab for liver metastases from colorectal cancer (European trial OPTILIV, NCT00852228).

scientific article

Pre-hospital management of pediatric polytrauma during modern conflict: experience and limits of the French military health service

scientific article published on 2 February 2018

Real-time PCR coupled with automated DNA extraction and detection of galactomannan antigen in serum by enzyme-linked immunosorbent assay for diagnosis of invasive aspergillosis

scientific article

Septin 9 induces lipid droplets growth by a phosphatidylinositol-5-phosphate and microtubule-dependent mechanism hijacked by HCV

scientific article

Single-cell transcriptomic profiling and characterization of endothelial progenitor cells: new approach for finding novel markers

scientific article published on 24 February 2021

Tetraspanin CD9 participates in dysmegakaryopoiesis and stromal interactions in primary myelofibrosis

scientific article published on 3 April 2015

Transcriptional landscape of a RETC634Y-mutated iPSC and its CRISPR-corrected isogenic control reveals the putative role of EGR1 transcriptional program in the development of multiple endocrine neoplasia type 2A-associated cancers

scientific article published on 23 November 2017

Transcriptome analysis of bone marrow mesenchymal stromal cells from patients with primary myelofibrosis.

scientific article published on 29 April 2015

V617F mutation in JAK2 is associated with poorer survival in idiopathic myelofibrosis

scientific article published on 17 November 2005

iPSC-Derived Embryoid Bodies as Models of c-Met-Mutated Hereditary Papillary Renal Cell Carcinoma

scientific article published on 30 September 2019

List of works by Christophe Desterke

A cross-talk between stromal cell-derived factor-1 and transforming growth factor-beta controls the quiescence/cycling switch of CD34(+) progenitors through FoxO3 and mammalian target of rapamycin

Assessment of sites of marrow and extramedullary hematopoiesis by hybrid imaging in primary myelofibrosis patients

Bone morphogenetic protein antagonist gene NOG is involved in myeloproliferative disease associated with myelofibrosis

CAGE profiling of ncRNAs in hepatocellular carcinoma reveals widespread activation of retroviral LTR promoters in virus-induced tumors.

CXCR4/CXCL12 axis counteracts hematopoietic stem cell exhaustion through selective protection against oxidative stress

CXCR7 participates in CXCL12-induced CD34+ cell cycling through β-arrestin-dependent Akt activation.

Cannabinoid receptor 1 is a major mediator of renal fibrosis.

Differentiation between isolates of Aspergillus fumigatus from breeding turkeys and their environment by genotyping with microsatellite markers

Dual SP/ALDH functionalities refine the human hematopoietic Lin-CD34+CD38- stem/progenitor cell compartment.

Effect of Allogeneic Oral Mucosa Mesenchymal Stromal Cells on Equine Wound Repair

Effects in Cancer Cells of the Recombinant l-Methionine Gamma-Lyase from Brevibacterium aurantiacum. Encapsulation in Human Erythrocytes for Sustained l-Methionine Elimination

Embryonic Program Activated during Blast Crisis of Chronic Myelogenous Leukemia (CML) Implicates a TCF7L2 and MYC Cooperative Chromatin Binding

Enteric Delivery of Regenerating Family Member 3 alpha Alters the Intestinal Microbiota and Controls Inflammation in Mice With Colitis

Experimental and integrative analyses identify an ETS1 network downstream BCR-ABL in chronic myeloid leukemia (CML).

Expression level and differential JAK2-V617F-binding of the adaptor protein Lnk regulates JAK2-mediated signals in myeloproliferative neoplasms

Expression of HMGA2 in PB leukocytes and purified CD34+ cells from controls and patients with Myelofibrosis and myeloid metaplasia

FLT3-mediated p38-MAPK activation participates in the control of megakaryopoiesis in primary myelofibrosis.

Gamma-smooth muscle actin expression is associated with epithelial-mesenchymal transition and stem-like properties in hepatocellular carcinoma

Genomic landscape analyses of reprogrammed cells using integrative and non-integrative methods reveal variable cancer-associated alterations

Global MicroRNA Profiling Uncovers miR-206 as a Negative Regulator of Hematopoietic Commitment in Human Pluripotent Stem Cells ⬇️

Hepatic and serum lipid signatures specific to nonalcoholic steatohepatitis in murine models

Hepatitis B virus pregenomic RNA in hepatocellular carcinoma: A nosological and prognostic determinant

Hepatitis C virus core protein targets 4E-BP1 expression and phosphorylation and potentiates Myc-induced liver carcinogenesis in transgenic mice

IL-8 and its CXCR1 and CXCR2 receptors participate in the control of megakaryocytic proliferation, differentiation, and ploidy in myeloid metaplasia with myelofibrosis

Inflammation as a Keystone of Bone Marrow Stroma Alterations in Primary Myelofibrosis

Metabolism dysregulation induces a specific lipid signature of nonalcoholic steatohepatitis in patients

Molecular Diversity and Routes of Colonization ofCandida albicansin a Surgical Intensive Care Unit, as Studied Using Microsatellite Markers

Osteogenic Potential of Mesenchymal Stromal Cells Contributes to Primary Myelofibrosis

Pharmacogenetic determinants of outcomes on triplet hepatic artery infusion and intravenous cetuximab for liver metastases from colorectal cancer (European trial OPTILIV, NCT00852228).

Pre-hospital management of pediatric polytrauma during modern conflict: experience and limits of the French military health service

Real-time PCR coupled with automated DNA extraction and detection of galactomannan antigen in serum by enzyme-linked immunosorbent assay for diagnosis of invasive aspergillosis

Septin 9 induces lipid droplets growth by a phosphatidylinositol-5-phosphate and microtubule-dependent mechanism hijacked by HCV

Single-cell transcriptomic profiling and characterization of endothelial progenitor cells: new approach for finding novel markers

Tetraspanin CD9 participates in dysmegakaryopoiesis and stromal interactions in primary myelofibrosis

Transcriptional landscape of a RETC634Y-mutated iPSC and its CRISPR-corrected isogenic control reveals the putative role of EGR1 transcriptional program in the development of multiple endocrine neoplasia type 2A-associated cancers

Transcriptome analysis of bone marrow mesenchymal stromal cells from patients with primary myelofibrosis.

V617F mutation in JAK2 is associated with poorer survival in idiopathic myelofibrosis

iPSC-Derived Embryoid Bodies as Models of c-Met-Mutated Hereditary Papillary Renal Cell Carcinoma

iPSC-derived Cancer Organoids Recapitulate Genomic and Phenotypic Alterations of c-met-mutated Hereditary Kidney Cancer