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List of works by Karen Skorupski

Binding site requirements of the virulence gene regulator AphB: differential affinities for the Vibrio cholerae classical and El Tor tcpPH promoters

scientific article

Characterization of BreR interaction with the bile response promoters breAB and breR in Vibrio cholerae

scientific article

Crystal Structure of the Vibrio cholerae Quorum-Sensing Regulatory Protein HapR

scientific article

Crystal structure of the virulence gene activator AphA from Vibrio cholerae reveals it is a novel member of the winged helix transcription factor superfamily

scientific article published on 12 January 2005

Dual regulation of genes involved in acetoin biosynthesis and motility/biofilm formation by the virulence activator AphA and the acetate-responsive LysR-type regulator AlsR in Vibrio cholerae

scientific article

H-NS Binding and Repression of the ctx Promoter in Vibrio cholerae

scientific article published on December 17, 2010

Identification of a Small Molecule Activator for AphB, a LysR-Type Virulence Transcriptional Regulator in Vibrio cholerae

scientific article published on 22 June 2017

Integration host factor positively regulates virulence gene expression in Vibrio cholerae

scientific article published on 2 May 2008

Levels of the secreted Vibrio cholerae attachment factor GbpA are modulated by quorum-sensing-induced proteolysis.

scientific article published on 4 September 2009

Parallel quorum sensing systems converge to regulate virulence in Vibrio cholerae.

scientific article

Proteolysis of virulence regulator ToxR is associated with entry of Vibrio cholerae into a dormant state.

scientific article published on 7 April 2015

Regulation of virulence gene expression in Vibrio cholerae by quorum sensing: HapR functions at the aphA promoter

article

Requirements for Vibrio cholerae HapR binding and transcriptional repression at the hapR promoter are distinct from those at the aphA promoter

scientific article published on May 2005

Role of FlgT in anchoring the flagellum of Vibrio cholerae.

scientific article

Structure of Vibrio cholerae ToxT reveals a mechanism for fatty acid regulation of virulence genes

scientific article

The 40-residue insertion in Vibrio cholerae FadR facilitates binding of an additional fatty acyl-CoA ligand.

scientific article

The Fatty Acid Regulator FadR Influences the Expression of the Virulence Cascade in the El Tor Biotype of Vibrio cholerae by Modulating the Levels of ToxT via Two Different Mechanisms

scientific article published on 23 January 2017

The LysR-type virulence activator AphB regulates the expression of genes in Vibrio cholerae in response to low pH and anaerobiosis

scientific article

The alternative sigma factor sigma(E) plays an important role in intestinal survival and virulence in Vibrio cholerae

scientific article

The crystal structure of AphB, a virulence gene activator from Vibrio cholerae, reveals residues that influence its response to oxygen and pH

scientific article

The quorum sensing regulator HapR downregulates the expression of the virulence gene transcription factor AphA in Vibrio cholerae by antagonizing Lrp- and VpsR-mediated activation

scientific article

The virulence activator AphA links quorum sensing to pathogenesis and physiology in Vibrio cholerae by repressing the expression of a penicillin amidase gene on the small chromosome

scientific article

Vibrio cholerae AphA uses a novel mechanism for virulence gene activation that involves interaction with the LysR-type regulator AphB at the tcpPH promoter

scientific article