Search filters

List of works by Dana Borden Lacy

2001: a year of major advances in anthrax toxin research

scientific article

A Nonoligomerizing Mutant Form of Helicobacter pylori VacA Allows Structural Analysis of the p33 Domain.

scientific article published on 5 July 2016

Analysis of TcdB Proteins within the Hypervirulent Clade 2 Reveals an Impact of RhoA Glucosylation on Clostridium difficile Proinflammatory Activities

scientific article published on 11 January 2016

Analysis of a beta-helical region in the p55 domain of Helicobacter pylori vacuolating toxin

scientific article

Antibacterial photosensitization through activation of coproporphyrinogen oxidase.

scientific article

Cloning and variation of ground state intestinal stem cells

scientific article published on 3 June 2015

Clostridioides difficile infection damages colonic stem cells via TcdB, impairing epithelial repair and recovery from disease

scientific article published on 20 March 2020

Clostridium difficile Toxin A Undergoes Clathrin-Independent, PACSIN2-Dependent Endocytosis

scientific article

Clostridium difficile Toxin B Causes Epithelial Cell Necrosis through an Autoprocessing-Independent Mechanism ⬇️

scientific article published on December 6, 2012

Clostridium difficile Toxins TcdA and TcdB Cause Colonic Tissue Damage by Distinct Mechanisms

scientific article published on 25 July 2016

Clostridium difficile toxin B-induced necrosis is mediated by the host epithelial cell NADPH oxidase complex

scientific article published on 28 October 2013

Clostridium difficile toxin glucosyltransferase domains in complex with a non-hydrolyzable UDP-glucose analogue.

scientific article published on 19 April 2017

Clostridium sordellii Lethal-Toxin Autoprocessing and Membrane Localization Activities Drive GTPase Glucosylation Profiles in Endothelial Cells

scientific article published on 18 November 2015

Control of antiviral innate immune response by protein geranylgeranylation

scientific article published on 29 May 2019

Cryo-EM Analysis Reveals Structural Basis of Helicobacter pylori VacA Toxin Oligomerization

scientific article published on 05 April 2019

Cryo-EM reveals species-specific components within the Helicobacter pylori Cag type IV secretion system core complex

scientific article published on 02 September 2020

Crystal structure of Clostridium difficile toxin A.

scientific article published on 11 January 2016

Crystal structure of botulinum neurotoxin type A and implications for toxicity

scientific article

Epitopes and Mechanism of Action of the Clostridium difficile Toxin A-Neutralizing Antibody Actoxumab.

scientific article

Exploiting dominant-negative toxins to combat Staphylococcus aureus pathogenesis

scientific article published on 8 February 2016

Exploiting dominant-negative toxins to combat Staphylococcus aureus pathogenesis

scientific article published on May 2016

Functional Properties of Oligomeric and Monomeric Forms of Helicobacter pylori VacA Toxin

scientific article published on 20 September 2021

Glucosyltransferase-dependent and independent effects of Clostridioides difficile toxins during infection

scientific article published on 17 February 2022

Integrated, High-Throughput, Multiomics Platform Enables Data-Driven Construction of Cellular Responses and Reveals Global Drug Mechanisms of Action.

scientific article

Intestinal bile acids directly modulate the structure and function of C. difficile TcdB toxin

scientific article published on 09 March 2020

Molecular assembly of botulinum neurotoxin progenitor complexes ⬇️

scientific article published on March 18, 2013

Molecular evolution of the Helicobacter pylori vacuolating toxin gene vacA

scientific article

Recombinant Expression and Purification of the Botulinum Neurotoxin Type A Translocation Domain ⬇️

scientific article published on 01 November 1997

Small Molecule Inhibitor Screen Reveals Calcium Channel Signaling as a Mechanistic Mediator of Clostridium difficile TcdB-Induced Necrosis

scientific article published on 14 January 2020

Structural analysis of the Legionella pneumophila Dot/Icm Type IV Secretion System Core Complex

scientific article published on 02 September 2020

Structural elucidation of the Clostridioides difficile transferase toxin reveals a single-site binding mode for the enzyme

scientific article published on 02 March 2020

Structural insights into the transition of Clostridioides difficile binary toxin from prepore to pore

scientific article published on 11 November 2019

Structure of the Cag type IV secretion system

scientific article published on 18 June 2019

The catalytic domains of Clostridium sordellii lethal toxin and related large clostridial glucosylating toxins specifically recognize the negatively charged phospholipids phosphatidylserine and phosphatidic acid.

scientific article published on 16 April 2015

The role of toxins in Clostridium difficile infection.

scientific article published on 18 October 2017

Toward a structural understanding of Clostridium difficile toxins A and B ⬇️

scientific article published on March 16, 2012

Translocation domain mutations affecting cellular toxicity identify the Clostridium difficile toxin B pore

scientific article

Use of a neutralizing antibody helps identify structural features critical for binding of Clostridium difficile toxin TcdA to the host cell surface

scientific article published on 13 July 2017

Zinc intoxication induces ferroptosis in A549 human lung cells

scientific article published on 01 May 2019

Paulina is supported by:

About Paulina

Help