List of works - Roland Foisner

141st ENMC International Workshop inaugural meeting of the EURO-Laminopathies project "Nuclear Envelope-linked Rare Human Diseases: From Molecular Pathophysiology towards Clinical Applications", 10-12 March 2006, Naarden, The Netherlands

scientific article published on 22 June 2007

A nuclear ubiquitin-proteasome pathway targets the inner nuclear membrane protein Asi2 for degradation

scientific article published on 13 June 2014

A phosphorylation cluster in the chromatin-binding region regulates chromosome association of LAP2alpha

scientific article

A-type lamin complexes and regenerative potential: a step towards understanding laminopathic diseases?

scientific article

A-type lamin networks in light of laminopathic diseases

scientific article published on 20 July 2006

A-type lamins bind both hetero- and euchromatin, the latter being regulated by lamina-associated polypeptide 2 alpha

scientific article published on 21 January 2016

AB091. Analysis of LA2 as a functional candidate gene for Emery Dreifuss muscular dystrophy and dilated cardiomyopathy.

scientific article published in September 2015

Atypical ubiquitylation in yeast targets lysine-less Asi2 for proteasomal degradation

scientific article published on 9 December 2014

Barrier-to-autointegration factor (BAF) involvement in prelamin A-related chromatin organization changes

scientific article published on 20 December 2015

Barrier-to-autointegration factor--a BAFfling little protein

scientific article published on 21 February 2007

Breaking and making of the nuclear envelope

scientific article

Cdc48 and Ubx1 participate in a pathway associated with the inner nuclear membrane that governs Asi1 degradation

scientific article published on 26 August 2016

Cell cycle dynamics of the nuclear envelope.

scientific article

Cytoskeleton architecture of C6 rat glioma cell subclones whole mount electron microscopy and immunogold labeling

scientific article published on January 1, 1996

Defective skeletal muscle growth in lamin A/C-deficient mice is rescued by loss of Lap2α.

scientific article published on 27 March 2013

Degradation-mediated protein quality control at the inner nuclear membrane

scientific article

DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells

scientific article

Distinct functions of the unique C terminus of LAP2alpha in cell proliferation and nuclear assembly

scientific article published on 25 February 2002

Drugs affecting prelamin A processing: effects on heterochromatin organization

scientific article

Editor's Corner

scientific article

Editor's corner.

scientific article

Evolvement of LEM proteins as chromatin tethers at the nuclear periphery

scientific article published on December 2011

High mobility group protein N5 (HMGN5) and lamina-associated polypeptide 2α (LAP2α) interact and reciprocally affect their genome-wide chromatin organization

scientific article published on 14 May 2013

In Vitro Techniques

Inhibition of lamin A/C attenuates osteoblast differentiation and enhances RANKL-dependent osteoclastogenesis

scientific article

Intermediate filaments: novel assembly models and exciting new functions for nuclear lamins ⬇️

scientific article published on August 1, 2003

LAP2alpha and BAF transiently localize to telomeres and specific regions on chromatin during nuclear assembly

scientific journal article

LAP2alpha-binding protein LINT-25 is a novel chromatin-associated protein involved in cell cycle exit

scientific article

LBR and lamin A/C sequentially tether peripheral heterochromatin and inversely regulate differentiation

scientific article published in January 2013

LEM2 is a novel MAN1-related inner nuclear membrane protein associated with A-type lamins

scientific article

Lamin A/C binding protein LAP2alpha is required for nuclear anchorage of retinoblastoma protein

scientific article

Lamin complexes in the nuclear interior control progenitor cell proliferation and tissue homeostasis

scientific article published on 20 May 2009

Lamin-binding Proteins

scientific article

Lamina-associated Polypeptide 2-α Forms Homo-trimers via Its C Terminus, and Oligomerization Is Unaffected by a Disease-causing Mutation

scientific article published in Journal of Biological Chemistry

Lamina-associated polypeptide (LAP)2α and nucleoplasmic lamins in adult stem cell regulation and disease

scientific article published on 25 December 2013

Lamina-associated polypeptide (LAP)2α and other LEM proteins in cancer biology

scientific article

Lamina-associated polypeptide 2alpha loss impairs heart function and stress response in mice

scientific article

Lamina-associated polypeptide 2alpha regulates cell cycle progression and differentiation via the retinoblastoma-E2F pathway.

scientific article published on April 2006

Lamins and lamin-associated proteins in aging and disease

scientific article published on 26 April 2007

Lamins at the crossroads of mechanosignaling

scientific article

Lamins in the nuclear interior - life outside the lamina

scientific article

Lamins reach out to novel functions in DNA damage repair

scientific article published on 15 October 2011

Lamins: 'structure goes cycling'.

scientific article

Lamins: nuclear intermediate filament proteins with fundamental functions in nuclear mechanics and genome regulation

scientific article

Lco1 is a novel widely expressed lamin-binding protein in the nuclear interior

scientific article

Loss of LAP2 alpha delays satellite cell differentiation and affects postnatal fiber-type determination

scientific article published in March 2010

Loss of nucleoplasmic LAP2alpha-lamin A complexes causes erythroid and epidermal progenitor hyperproliferation

scientific article

Molecular aspects of epithelial cell plasticity: implications for local tumor invasion and metastasis.

scientific article published on January 2004

Molecular insights into the premature aging disease progeria

scientific article

Monoclonal antibodies specific for disease-associated point-mutants: lamin A/C R453W and R482W

scientific article (publication date: 13 May 2010)

Multiple novel functions of lamina associated polypeptide 2α in striated muscle

scientific article published on September 2010

Nuclear envelope localization of LEMD2 is developmentally dynamic and lamin A/C dependent yet insufficient for heterochromatin tethering

scientific article

Nucleo-cytoplasmic shuttling of the endonuclease ankyrin repeats and LEM domain-containing protein 1 (Ankle1) is mediated by canonical nuclear export- and nuclear import signals

scientific article

Nucleoplasmic LAP2alpha-lamin A complexes are required to maintain a proliferative state in human fibroblasts

scientific article

Nucleoplasmic lamins and their interaction partners, LAP2alpha, Rb, and BAF, in transcriptional regulation.

scientific article

Nucleoplasmic lamins define growth-regulating functions of lamina-associated polypeptide 2α in progeria cells

scientific article published on 28 December 2017

Pre-Lamin A processing is linked to heterochromatin organization.

scientific article published in December 2007

Prelamin A is involved in early steps of muscle differentiation.

scientific article

Proliferation of progeria cells is enhanced by lamina-associated polypeptide 2α (LAP2α) through expression of extracellular matrix proteins

scientific article

Proteins that associate with lamins: many faces, many functions.

scientific article published on 24 March 2007

Regulation by estrogen of synthesis and secretion of apolipoprotein A-I in the chicken hepatoma cell line, LMH-2A.

scientific article published on June 2003

Sun1 forms immobile macromolecular assemblies at the nuclear envelope

scientific article

The GIY-YIG Type Endonuclease Ankyrin Repeat and LEM Domain-Containing Protein 1 (ANKLE1) Is Dispensable for Mouse Hematopoiesis

scientific journal article

The LEM domain proteins emerin and LAP2alpha are dispensable for human immunodeficiency virus type 1 and murine leukemia virus infections.

scientific article published on 9 April 2008

The endonuclease Ankle1 requires its LEM and GIY-YIG motifs for DNA cleavage in vivo

scientific journal article

The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope

scientific article

The muscle dystrophy-causing ΔK32 lamin A/C mutant does not impair the functions of the nucleoplasmic lamin-A/C-LAP2α complex in mice

scientific article published on 26 February 2013

The nuclear envelope from basic biology to therapy

scientific article published in February 2010

The transcription factor ZEB1 (deltaEF1) represses Plakophilin 3 during human cancer progression

scientific article

Thymopoietin (lamina-associated polypeptide 2) gene mutation associated with dilated cardiomyopathy

scientific article published in December 2005

beta-Catenin and TGFbeta signalling cooperate to maintain a mesenchymal phenotype after FosER-induced epithelial to mesenchymal transition.

scientific article published on April 2004

List of works by Roland Foisner

141st ENMC International Workshop inaugural meeting of the EURO-Laminopathies project "Nuclear Envelope-linked Rare Human Diseases: From Molecular Pathophysiology towards Clinical Applications", 10-12 March 2006, Naarden, The Netherlands

A nuclear ubiquitin-proteasome pathway targets the inner nuclear membrane protein Asi2 for degradation

A phosphorylation cluster in the chromatin-binding region regulates chromosome association of LAP2alpha

A-type lamin complexes and regenerative potential: a step towards understanding laminopathic diseases?

A-type lamin networks in light of laminopathic diseases

A-type lamins bind both hetero- and euchromatin, the latter being regulated by lamina-associated polypeptide 2 alpha

AB091. Analysis of LA2 as a functional candidate gene for Emery Dreifuss muscular dystrophy and dilated cardiomyopathy.

Atypical ubiquitylation in yeast targets lysine-less Asi2 for proteasomal degradation

Barrier-to-autointegration factor (BAF) involvement in prelamin A-related chromatin organization changes

Barrier-to-autointegration factor--a BAFfling little protein

Breaking and making of the nuclear envelope

Cdc48 and Ubx1 participate in a pathway associated with the inner nuclear membrane that governs Asi1 degradation

Cell cycle dynamics of the nuclear envelope.

Cytoskeleton architecture of C6 rat glioma cell subclones whole mount electron microscopy and immunogold labeling

Defective skeletal muscle growth in lamin A/C-deficient mice is rescued by loss of Lap2α.

Degradation-mediated protein quality control at the inner nuclear membrane

DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells

Distinct functions of the unique C terminus of LAP2alpha in cell proliferation and nuclear assembly

Drugs affecting prelamin A processing: effects on heterochromatin organization

Editor's Corner

Editor's corner.

Evolvement of LEM proteins as chromatin tethers at the nuclear periphery

High mobility group protein N5 (HMGN5) and lamina-associated polypeptide 2α (LAP2α) interact and reciprocally affect their genome-wide chromatin organization

In Vitro Techniques

Inhibition of lamin A/C attenuates osteoblast differentiation and enhances RANKL-dependent osteoclastogenesis

Intermediate filaments: novel assembly models and exciting new functions for nuclear lamins ⬇️

LAP2alpha and BAF transiently localize to telomeres and specific regions on chromatin during nuclear assembly

LAP2alpha-binding protein LINT-25 is a novel chromatin-associated protein involved in cell cycle exit

LBR and lamin A/C sequentially tether peripheral heterochromatin and inversely regulate differentiation

LEM2 is a novel MAN1-related inner nuclear membrane protein associated with A-type lamins

Lamin A/C binding protein LAP2alpha is required for nuclear anchorage of retinoblastoma protein

Lamin complexes in the nuclear interior control progenitor cell proliferation and tissue homeostasis

Lamin-binding Proteins

Lamina-associated Polypeptide 2-α Forms Homo-trimers via Its C Terminus, and Oligomerization Is Unaffected by a Disease-causing Mutation

Lamina-associated polypeptide (LAP)2α and nucleoplasmic lamins in adult stem cell regulation and disease

Lamina-associated polypeptide (LAP)2α and other LEM proteins in cancer biology

Lamina-associated polypeptide 2alpha loss impairs heart function and stress response in mice

Lamina-associated polypeptide 2alpha regulates cell cycle progression and differentiation via the retinoblastoma-E2F pathway.

Lamins and lamin-associated proteins in aging and disease

Lamins at the crossroads of mechanosignaling

Lamins in the nuclear interior - life outside the lamina

Lamins reach out to novel functions in DNA damage repair

Lamins: 'structure goes cycling'.

Lamins: nuclear intermediate filament proteins with fundamental functions in nuclear mechanics and genome regulation

Lco1 is a novel widely expressed lamin-binding protein in the nuclear interior

Loss of LAP2 alpha delays satellite cell differentiation and affects postnatal fiber-type determination

Loss of nucleoplasmic LAP2alpha-lamin A complexes causes erythroid and epidermal progenitor hyperproliferation

Molecular aspects of epithelial cell plasticity: implications for local tumor invasion and metastasis.

Molecular insights into the premature aging disease progeria

Monoclonal antibodies specific for disease-associated point-mutants: lamin A/C R453W and R482W

Multiple novel functions of lamina associated polypeptide 2α in striated muscle

Nuclear envelope localization of LEMD2 is developmentally dynamic and lamin A/C dependent yet insufficient for heterochromatin tethering

Nucleo-cytoplasmic shuttling of the endonuclease ankyrin repeats and LEM domain-containing protein 1 (Ankle1) is mediated by canonical nuclear export- and nuclear import signals

Nucleoplasmic LAP2alpha-lamin A complexes are required to maintain a proliferative state in human fibroblasts

Nucleoplasmic lamins and their interaction partners, LAP2alpha, Rb, and BAF, in transcriptional regulation.

Nucleoplasmic lamins define growth-regulating functions of lamina-associated polypeptide 2α in progeria cells

Pre-Lamin A processing is linked to heterochromatin organization.

Prelamin A is involved in early steps of muscle differentiation.

Proliferation of progeria cells is enhanced by lamina-associated polypeptide 2α (LAP2α) through expression of extracellular matrix proteins

Proteins that associate with lamins: many faces, many functions.

Regulation by estrogen of synthesis and secretion of apolipoprotein A-I in the chicken hepatoma cell line, LMH-2A.

Sun1 forms immobile macromolecular assemblies at the nuclear envelope

The GIY-YIG Type Endonuclease Ankyrin Repeat and LEM Domain-Containing Protein 1 (ANKLE1) Is Dispensable for Mouse Hematopoiesis

The LEM domain proteins emerin and LAP2alpha are dispensable for human immunodeficiency virus type 1 and murine leukemia virus infections.

The endonuclease Ankle1 requires its LEM and GIY-YIG motifs for DNA cleavage in vivo

The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope

The muscle dystrophy-causing ΔK32 lamin A/C mutant does not impair the functions of the nucleoplasmic lamin-A/C-LAP2α complex in mice

The nuclear envelope from basic biology to therapy

The transcription factor ZEB1 (deltaEF1) represses Plakophilin 3 during human cancer progression

Thymopoietin (lamina-associated polypeptide 2) gene mutation associated with dilated cardiomyopathy

beta-Catenin and TGFbeta signalling cooperate to maintain a mesenchymal phenotype after FosER-induced epithelial to mesenchymal transition.