Search filters

List of works by Li Yang

20(S)-Protopanaxadiol enhances angiogenesis via HIF-1α-mediated VEGF secretion by activating p70S6 kinase and benefits wound healing in genetically diabetic mice

scientific article published on 27 October 2017

A quantitative ¹H nuclear magnetic resonance (qHNMR) method for assessing the purity of iridoids and secoiridoids

scientific article published on 13 December 2014

Abietane Diterpenoids from the Roots of Clerodendrum trichotomum and Their Nitric Oxide Inhibitory Activities

scientific article published on 20 June 2018

An efficient way from naringenin to carthamidine and isocarthamidine by Aspergillus niger

scientific article published on 06 November 2011

An integrated method for optimized identification of effective natural inhibitors against SARS-CoV-2 3CLpro

scientific article published on 23 November 2021

An integrative investigation on the efficacy of Plantaginis semen based on UPLC-QTOF-MS metabolomics approach in hyperlipidemic mice

scientific article published on 06 May 2019

Analysis of bioactive components and multi-component pharmacokinetics of saponins from the leaves of Panax notoginseng in rat plasma after oral administration by LC-MS/MS.

scientific article published on 26 December 2017

Beneficial effect of resveratrol on α‑naphthyl isothiocyanate‑induced cholestasis via regulation of the FXR pathway.

scientific article published on 14 November 2017

Betulinic acid alleviates endoplasmic reticulum stress-mediated nonalcoholic fatty liver disease through activation of farnesoid X receptors in mice

scientific article published on 18 March 2019

Characterization of the Principal Constituents of Danning Tablets, a Chinese Formula Consisting of Seven Herbs, by an UPLC-DAD-MS/MS Approach.

scientific article published on 14 May 2016

Chicken bile powder protects against α-naphthylisothiocyanate-induced cholestatic liver injury in mice.

scientific article published on 27 September 2017

Clivorine, an otonecine pyrrolizidine alkaloid from Ligularia species, impairs neuronal differentiation via NGF-induced signaling pathway in cultured PC12 cells

scientific article published on 10 June 2016

Comprehensive Analysis of Serum and Fecal Bile Acid Profiles and Interaction with Gut Microbiota in Primary Biliary Cholangitis

scientific article published on 01 February 2020

Curcumin rescues high fat diet-induced obesity and insulin sensitivity in mice through regulating SREBP pathway.

scientific article

Cycloastragenol improves hepatic steatosis by activating farnesoid X receptor signalling.

scientific article published on 17 April 2017

Danning tablets attenuates α-naphthylisothiocyanate-induced cholestasis by modulating the expression of transporters and metabolic enzymes

scientific article

Decichine enhances hemostasis of activated platelets via AMPA receptors

scientific article published on 22 February 2014

Deletion of mouse FXR gene disturbs multiple neurotransmitter systems and alters neurobehavior

scientific article

Dendrobium chrysotoxum Lindl. alleviates diabetic retinopathy by preventing retinal inflammation and tight junction protein decrease

scientific article

Dose-Related Urinary Metabolic Alterations of a Combination of Quercetin and Resveratrol-Treated High-Fat Diet Fed Rats

scientific article published on 16 April 2021

Four new compounds from Imperata cylindrica

scientific article published on 20 July 2013

Fully automated chip-based nanoelectrospray ionization-mass spectrometry as an effective tool for rapid and high-throughput screening of 5α-reductase inhibitors

scientific article published on 01 February 2020

Gas chromatography–mass spectrometry‐based profiling of serum fatty acids in acetaminophen‐induced liver injured rats

scientific article published on December 12, 2012

Ginsenoside Rd regulates the Akt/mTOR/p70S6K signaling cascade and suppresses angiogenesis and breast tumor growth.

scientific article published on 19 May 2017

Gypenosides Altered Hepatic Bile Acids Homeostasis in Mice Treated with High Fat Diet

scientific article published on 12 July 2018

Huangqi decoction alleviates dimethylnitrosamine-induced liver fibrosis: An analysis of bile acids metabolic mechanism

scientific article published on 16 May 2016

Identification and characterization of forced degradation products and stability-indicating assay for notoginsenosidefc by using UHPLC-Q-TOF-MS and UHPLC-MS/MS: Insights into stability profile and degradation pathways

scientific article published on 10 March 2019

Identification and quantitative investigation of the effects of intestinal microflora on the metabolism and pharmacokinetics of notoginsenoside Fc assayed by liquid chromatography with electrospray ionization tandem mass spectrometry

scientific article published on 10 March 2019

Identification of 20(S)-protopanaxatriol metabolites in rats by ultra-performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry and nuclear magnetic resonance spectroscopy.

scientific article published on 14 October 2013

Identification of Human UDP-Glucuronosyltransferase 1A4 as the Major Isozyme Responsible for the Glucuronidation of 20(S)-Protopanaxadiol in Human Liver Microsomes.

scientific article published on 9 March 2016

Identification of bio‐active metabolites of gentiopicroside by UPLC/Q‐TOF MS and NMR

scientific article published on June 4, 2013

Identification of metabolites of geniposide in rat urine using ultra‐performance liquid chromatography combined with electrospray ionization quadrupole time‐of‐flight tandem mass spectrometry

scientific article published on November 15, 2011

Identification of the metabolites of gigantol in rat urine by ultra-performance liquid chromatography combined with electrospray ionization quadrupole time-of-flight tandem mass spectrometry.

scientific article

Intestinal AMPK modulation of microbiota mediates crosstalk with brown fat to control thermogenesis

scientific article published on 03 March 2022

Large-scale production of tauroursodeoxycholic acid products through fermentation optimization of engineered Escherichia coli cell factory

scientific article published on 08 February 2019

Metabolic profiles of 20(S)-protopanaxadiol in rats after oral administration using ultra-performance liquid chromatography/quadrupole time-of-flight tandem mass spectrometry

scientific article published on 01 March 2014

Metabolism of Genipin in Rat and Identification of Metabolites by Using Ultraperformance Liquid Chromatography/Quadrupole Time-of-Flight Tandem Mass Spectrometry

scientific article published on March 19, 2013

Notoginsenoside Ft1 promotes angiogenesis via HIF-1α mediated VEGF secretion and the regulation of PI3K/AKT and Raf/MEK/ERK signaling pathways

scientific article published on July 4, 2012

Overexpression of SmMYB9b enhances tanshinone concentration in Salvia miltiorrhiza hairy roots.

scientific article published on 15 May 2017

Pharmacokinetics and tissue distribution of five active ingredients of Eucommiae cortex in normal and ovariectomized mice by UHPLC-MS/MS.

scientific article published on 10 January 2016

Plantadeprate A, a Tricyclic Monoterpene Zwitterionic Guanidium, and Related Derivatives from the Seeds of Plantago depressa

scientific article published on 12 November 2015

Platelet P2Y₁₂ receptors are involved in the haemostatic effect of notoginsenoside Ft1, a saponin isolated from Panax notoginseng

scientific article published on January 2014

Protective effect of Danning tablet on acute livery injury with cholestasis induced by α-naphthylisothiocyanate in rats

scientific article published on January 16, 2012

Protective effect of cultured bear bile powder against dimethylnitrosamine-induced hepatic fibrosis in rats

scientific article published on 25 February 2019

Quantification of 1‐13C‐l‐methionine in rat serum with hydrophilic interaction liquid chromatography coupled with tandem mass spectrometry and its application in pharmacokinetic study

scientific article published on February 2, 2011

Rapid authentication of agarwood by using liquid extraction surface analysis mass spectrometry (LESA-MS)

scientific article published on 27 April 2020

Rapidly directional biotransformation of tauroursodeoxycholic acid through engineered Escherichia coli.

scientific article published on 22 March 2017

Separation and Quantification of Four Main Chiral Glucosinolates in Radix Isatidis and Its Granules Using High-Performance Liquid Chromatography/Diode Array Detector Coupled with Circular Dichroism Detection.

scientific article

Silymarin Ameliorates Metabolic Dysfunction Associated with Diet-Induced Obesity via Activation of Farnesyl X Receptor.

scientific article published on 28 September 2016

Simultaneous determination of norisoboldine and its major metabolite in rat plasma by ultra‐performance liquid chromatography–mass spectrometry and its application in a pharmacokinetic study

scientific article published on March 1, 2011

Simultaneous quantification of seven hippocampal neurotransmitters in depression mice by LC-MS/MS.

scientific article published on 13 April 2014

Simultaneous quantitation of 23 bioactive compounds in Tanreqing capsule by high-performance liquid chromatography electrospray ionization tandem mass spectrometry

scientific article published on 26 March 2019

Structures and biological evaluation of phenylpropanoid derivatives from Dendrobium Sonia

scientific article published on 31 August 2020

Sweroside ameliorated carbon tetrachloride (CCl4)-induced liver fibrosis through FXR-miR-29a signaling pathway

scientific article published on 06 July 2019

Targeting Bile Acid-Activated Receptors in Bariatric Surgery

scientific article published on 01 January 2019

The Chinese Herbal Decoction Danggui Buxue Tang Inhibits Angiogenesis in a Rat Model of Liver Fibrosis

scientific article published on July 29, 2012

The comparative pharmacokinetics of two pyrrolizidine alkaloids, senecionine and adonifoline, and their main metabolites in rats after intravenous and oral administration by UPLC/ESIMS

scientific article published on May 15, 2011

The long persistence of pyrrolizidine alkaloid-derived pyrrole-protein adducts in vivo: Kinetic study following multiple exposures of a pyrrolizidine alkaloid containing extract of Gynura japonica

scientific article published on 23 January 2020

Three New Sesquiterpenoids and One New Sesquiterpenoid Derivative from Chinese Eaglewood.

scientific article

Three new C-glycosyflavones with acetyl substitutions from Swertia mileensis

scientific article published on 26 July 2018

Two new phenolic glycosides from the rhizome ofGastrodia elata

scientific article published on March 20, 2012