List of works - Alberto Visintin

A Novel Factor H-Fc Chimeric Immunotherapeutic Molecule against Neisseria gonorrhoeae

scientific article published on 15 January 2016

A point mutation in the amino terminus of TLR7 abolishes signaling without affecting ligand binding

scientific article published on 7 March 2011

Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein

scientific article

Bacterial fimbriae stimulate proinflammatory activation in the endothelium through distinct TLRs

scientific article published on February 2008

Human factor H interacts selectively with Neisseria gonorrhoeae and results in species-specific complement evasion

scientific article published in March 2008

IL-10 enhances MD-2 and CD14 expression in monocytes and the proteins are increased and correlated in HIV-infected patients

scientific article

Inhibition of TLR-4/MD-2 signaling by RP105/MD-1

article

Inhibition of TLR-4/MD-2 signaling by RP105/MD-1.

scientific article published on January 2005

LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF

scientific article

Ligand-induced conformational changes allosterically activate Toll-like receptor 9.

scientific article published on 17 June 2007

Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction

scientific article (publication date: 6 December 2002)

Localization of TLR2 and MyD88 to Chlamydia trachomatis inclusions. Evidence for signaling by intracellular TLR2 during infection with an obligate intracellular pathogen.

scientific article

Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transduction

scientific article (publication date: 28 November 2003)

MD-2 expression is not required for cell surface targeting of Toll-like receptor 4 (TLR4).

scientific article published on 31 August 2006

MD-2.

scientific article published on 18 July 2006

Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9.

scholarly article

Mechanisms of TLR9 activation.

scientific article

Meningococcal porin PorB binds to TLR2 and requires TLR1 for signaling

scientific journal article

Molecular Characterization of the Interaction between Sialylated Neisseria gonorrhoeae and Factor H ⬇️

scientific article published on April 29, 2011

Myeloid suppressor lines inhibit T cell responses by an NO-dependent mechanism.

scientific article

Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105

scientific article

Novel Anti-TM4SF1 Antibody-Drug Conjugates with Activity against Tumor Cells and Tumor Vasculature

scientific article

Phagocytosis and intracellular killing of MD-2 opsonized gram-negative bacteria depend on TLR4 signaling

scientific article published on 18 January 2008

Pharmacological inhibition of endotoxin responses is achieved by targeting the TLR4 coreceptor, MD-2.

scientific article published on November 2005

TLR9 signals after translocating from the ER to CpG DNA in the lysosome

scientific article published on 11 January 2004

Targeted therapy of solid malignancies via HLA class II antigens: a new biotherapeutic approach? ⬇️

scientific article published on September 29, 2003

Targeting of HLA-DR molecules transduces agonistic functional signals in cutaneous melanoma

scientific article

The LPS receptor generates inflammatory signals from the cell surface

scientific article published on January 2003

The apoptotic response to pneumolysin is Toll-like receptor 4 dependent and protects against pneumococcal disease

scientific article

The functional repertoire of rabbit antibodies and antibody discovery via next-generation sequencing

scientific article

The role of disulfide bonds in the assembly and function of MD-2

scientific article

Toll-like receptor 1 inhibits Toll-like receptor 4 signaling in endothelial cells

scientific article published on April 2002

Trypsin-sensitive modulation of intestinal epithelial MD-2 as mechanism of lipopolysaccharide tolerance

scientific article

List of works by Alberto Visintin

A Novel Factor H-Fc Chimeric Immunotherapeutic Molecule against Neisseria gonorrhoeae

A point mutation in the amino terminus of TLR7 abolishes signaling without affecting ligand binding

Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein

Bacterial fimbriae stimulate proinflammatory activation in the endothelium through distinct TLRs

Human factor H interacts selectively with Neisseria gonorrhoeae and results in species-specific complement evasion

IL-10 enhances MD-2 and CD14 expression in monocytes and the proteins are increased and correlated in HIV-infected patients

Inhibition of TLR-4/MD-2 signaling by RP105/MD-1

Inhibition of TLR-4/MD-2 signaling by RP105/MD-1.

LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF

Ligand-induced conformational changes allosterically activate Toll-like receptor 9.

Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction

Localization of TLR2 and MyD88 to Chlamydia trachomatis inclusions. Evidence for signaling by intracellular TLR2 during infection with an obligate intracellular pathogen.

Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transduction

MD-2 expression is not required for cell surface targeting of Toll-like receptor 4 (TLR4).

MD-2.

Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9.

Mechanisms of TLR9 activation.

Meningococcal porin PorB binds to TLR2 and requires TLR1 for signaling

Molecular Characterization of the Interaction between Sialylated Neisseria gonorrhoeae and Factor H ⬇️

Myeloid suppressor lines inhibit T cell responses by an NO-dependent mechanism.

Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105

Novel Anti-TM4SF1 Antibody-Drug Conjugates with Activity against Tumor Cells and Tumor Vasculature

Phagocytosis and intracellular killing of MD-2 opsonized gram-negative bacteria depend on TLR4 signaling

Pharmacological inhibition of endotoxin responses is achieved by targeting the TLR4 coreceptor, MD-2.

TLR9 signals after translocating from the ER to CpG DNA in the lysosome

Targeted therapy of solid malignancies via HLA class II antigens: a new biotherapeutic approach? ⬇️

Targeting of HLA-DR molecules transduces agonistic functional signals in cutaneous melanoma

The LPS receptor generates inflammatory signals from the cell surface

The apoptotic response to pneumolysin is Toll-like receptor 4 dependent and protects against pneumococcal disease

The functional repertoire of rabbit antibodies and antibody discovery via next-generation sequencing

The role of disulfide bonds in the assembly and function of MD-2

Toll-like receptor 1 inhibits Toll-like receptor 4 signaling in endothelial cells

Trypsin-sensitive modulation of intestinal epithelial MD-2 as mechanism of lipopolysaccharide tolerance