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List of works by Brian M Zeglis

(18)F-Based Pretargeted PET Imaging Based on Bioorthogonal Diels-Alder Click Chemistry.

scientific article published on 19 October 2015

89Zr-Labeled AR20.5: A MUC1-Targeting ImmunoPET Probe

scientific article published on 15 May 2020

A Bone-Seeking trans-Cyclooctene for Pretargeting and Bioorthogonal Chemistry: A Proof of Concept Study Using 99mTc- and 177Lu-Labeled Tetrazines.

scientific article published on 5 October 2016

A Bulky Rhodium Complex Bound to an Adenosine-Adenosine DNA Mismatch: General Architecture of the Metalloinsertion Binding Mode

scientific article

A Molecularly Targeted Intraoperative Near-Infrared Fluorescence Imaging Agent for High-Grade Serous Ovarian Cancer

scientific article published on 16 July 2020

A Novel Technique for Generating and Observing Chemiluminescence in a Biological Setting

scientific article

A Pretargeted Approach for the Multimodal PET/NIRF Imaging of Colorectal Cancer. ⬇️

scientific article published on 28 September 2016

A brief overview of metal complexes as nuclear imaging agents

scientific article published on 01 October 2019

A comparative evaluation of the chelators H4octapa and CHX-A″-DTPA with the therapeutic radiometal (90)Y.

scientific article published on 28 June 2016

A mismatch-selective bifunctional rhodium-Oregon Green conjugate: a fluorescent probe for mismatched DNA.

scientific article published on May 2006

A practical guide to the construction of radiometallated bioconjugates for positron emission tomography.

scientific article published on 25 March 2011

A pretargeted PET imaging strategy based on bioorthogonal Diels-Alder click chemistry.

scientific article published on 24 May 2013

Alternative chelator for ⁸⁹Zr radiopharmaceuticals: radiolabeling and evaluation of 3,4,3-(LI-1,2-HOPO).

scientific article

Binding of Ru(bpy)2(eilatin)2+ to matched and mismatched DNA.

scientific article published on 25 June 2008

Building Blocks for the Construction of Bioorthogonally Reactive Peptides via Solid-Phase Peptide Synthesis.

scientific article published on 06 April 2014

Chemoenzymatic strategy for the synthesis of site-specifically labeled immunoconjugates for multimodal PET and optical imaging

scientific article published on 26 November 2014

Click Chemistry and Radiochemistry: The First 10 Years

scientific article published on 27 October 2016

Click-Mediated Pretargeted Radioimmunotherapy of Colorectal Carcinoma.

scientific article published on 5 March 2018

DNA base mismatch detection with bulky rhodium intercalators: synthesis and applications

scientific article published on January 2007

Dendrimer Scaffold for the Amplification of In Vivo Pretargeting Ligations.

scientific article published on 18 July 2018

Design and synthesis of promiscuous high-affinity monoamine transporter ligands: unraveling transporter selectivity

scientific article published in March 2006

DiPODS: A Reagent for Site-Specific Bioconjugation via the Irreversible Rebridging of Disulfide Linkages

scientific article published on 19 November 2020

Dual Radionuclide Theranostic Pretargeting

scientific article published on 09 September 2019

ESPMIS: Helping Young Scientists Navigate the Molecular Imaging Landscape.

scientific article published on 13 February 2017

Enzyme-mediated methodology for the site-specific radiolabeling of antibodies based on catalyst-free click chemistry

scientific article published on 30 May 2013

Establishment of the In Vivo Efficacy of Pretargeted Radioimmunotherapy Utilizing Inverse Electron Demand Diels-Alder Click Chemistry

scientific article published on 9 November 2016

Exploring Structural Parameters for Pretargeting Radioligand Optimization

scientific article

Fc-mediated Anomalous Biodistribution of Therapeutic Antibodies in Immunodeficient Mouse Models.

scientific article published on 23 January 2018

First-in-human HER2-targeted imaging using 89Zr-pertuzumab PET/CT: Dosimetry and clinical application in patients with breast cancer

scientific article published on 16 November 2017

H(2)azapa: a versatile acyclic multifunctional chelator for (67)Ga, (64)Cu, (111)In, and (177)Lu

scientific article published on 29 October 2012

H(4)octapa-trastuzumab: versatile acyclic chelate system for 111In and 177Lu imaging and therapy

scientific article published on 15 August 2013

H6phospa-trastuzumab: bifunctional methylenephosphonate-based chelator with 89Zr, 111In and 177Lu.

scientific article published on January 2014

Harnessing 64Cu/67Cu for a theranostic approach to pretargeted radioimmunotherapy

scientific article published on 26 October 2020

Harnessing the bioorthogonal inverse electron demand Diels-Alder cycloaddition for pretargeted PET imaging

scientific article

Identification of HER2-Positive Metastases in Patients with HER2-Negative Primary Breast Cancer by Using HER2-targeted 89Zr-Pertuzumab PET/CT

scientific article published on 09 June 2020

Inverse electron demand Diels–Alder click chemistry for pretargeted PET imaging and radioimmunotherapy

scientific article published in 2021

Leveraging bioorthogonal click chemistry to improve 225Ac-radioimmunotherapy of pancreatic ductal adenocarcinoma

scientific article published on 23 October 2018

Manipulating the In Vivo Behaviour of 68Ga with Tris(Hydroxypyridinone) Chelators: Pretargeting and Blood Clearance

scientific article published on 22 February 2020

Metallo-intercalators and metallo-insertors

scientific article published on 20 September 2007

Modular strategy for the construction of radiometalated antibodies for positron emission tomography based on inverse electron demand Diels-Alder click chemistry

scientific article

Molecular Imaging of Ovarian Cancer

scientific article published on 28 April 2016

Near-Infrared Intraoperative Chemiluminescence Imaging

scientific article published on 29 July 2016

Noninvasive Interrogation of DLL3 Expression in Metastatic Small Cell Lung Cancer

scientific article published on 9 May 2017

On the consensus nomenclature rules for radiopharmaceutical chemistry - Reconsideration of radiochemical conversion

scientific article published on 18 November 2020

Optimization of a Pretargeted Strategy for the PET Imaging of Colorectal Carcinoma via the Modulation of Radioligand Pharmacokinetics.

scientific article

PARP1-Targeted Radiotherapy in Mouse Models of Glioblastoma.

scientific article published on 23 March 2018

PET imaging with ⁸⁹Zr: from radiochemistry to the clinic

scientific article

Poly(ADP-Ribose)Polymerase (PARP) Inhibitors and Radiation Therapy

scientific article published on 03 March 2020

Preclinical 89Zr Immuno-PET of High-Grade Serous Ovarian Cancer and Lymph Node Metastasis.

scientific article published on 02 February 2016

Pretargeted Imaging and Therapy

scientific article

Pretargeted Immuno-PET of Pancreatic Cancer: Overcoming Circulating Antigen and Internalized Antibody to Reduce Radiation Doses

scientific article published on 15 October 2015

Pretargeted PET Imaging Using a Site-Specifically Labeled Immunoconjugate

scientific article published on 29 June 2016

Pretargeted Radioimmunotherapy Based on the Inverse Electron Demand Diels-Alder Reaction

scientific article published on 29 January 2019

Pretargeted radioimmunotherapy and SPECT imaging of peritoneal carcinomatosis using bioorthogonal click chemistry: probe selection and first proof-of-concept

scientific article published on 19 September 2019

Pretargeting of internalizing trastuzumab and cetuximab with a 18F-tetrazine tracer in xenograft models

scientific article published on 2 December 2017

Recognition of abasic sites and single base bulges in DNA by a metalloinsertor

scientific article published on February 2009

Removal of Fc Glycans from [89Zr]Zr-DFO-anti-CD8 prevents peripheral depletion of CD8+ T cells

scientific article published on 24 April 2020

Role of metalation in the topoisomerase IIα inhibition and antiproliferation activity of a series of α-heterocyclic-N4-substituted thiosemicarbazones and their Cu(II) complexes.

scientific article published on 10 March 2011

Site-Specifically Labeled Antibody-Drug Conjugate for Simultaneous Therapy and ImmunoPET.

scientific article published on 22 January 2018

Site-Specifically Labeled Immunoconjugates for Molecular Imaging--Part 1: Cysteine Residues and Glycans

scientific article

Site-Specifically Labeled Immunoconjugates for Molecular Imaging--Part 2: Peptide Tags and Unnatural Amino Acids

scientific article

Site-specifically labeled CA19.9-targeted immunoconjugates for the PET, NIRF, and multimodal PET/NIRF imaging of pancreatic cancer.

scientific article

Synthesis and Bioconjugation of Thiol-Reactive Reagents for the Creation of Site-Selectively Modified Immunoconjugates

scientific article published on 06 March 2019

Synthesis and evaluation of (18)F-labeled ATP competitive inhibitors of topoisomerase II as probes for imaging topoisomerase II expression.

scientific article published on 8 September 2014

Synthesis of the first radiolabeled 188Re N-heterocyclic carbene complex and initial studies on its potential use in radiopharmaceutical applications

scientific article published on 29 May 2014

Targeted brain tumor radiotherapy using an Auger emitter

scientific article published on 17 February 2020

Targeting Triple Negative Breast Cancer with a Nucleus-Directed p53 Tetramerization Domain Peptide

scientific article published on 08 December 2020

Targeting abasic sites and single base bulges in DNA with metalloinsertors

scientific article published on 21 May 2008

The Impact of FcγRI Binding on Immuno-PET

scientific article published on 07 February 2019

The Influence of Glycans-Specific Bioconjugation on the FcγRI Binding and In vivo Performance of 89Zr-DFO-Pertuzumab

scientific article published on 01 January 2020

The bioconjugation and radiosynthesis of 89Zr-DFO-labeled antibodies

scientific article

The inverse electron demand Diels-Alder click reaction in radiochemistry

scientific article published on 18 December 2013

The synthesis and evaluation of N1-(4-(2-[18F]-fluoroethyl)phenyl)-N8-hydroxyoctanediamide ([18F]-FESAHA), a PET radiotracer designed for the delineation of histone deacetylase expression in cancer.

scientific article

Thiol-Reactive Bifunctional Chelators for the Creation of Site-Selectively Modified Radioimmunoconjugates with Improved Stability.

scientific article published on 6 March 2018

Toward the Optimization of Click-Mediated Pretargeted Radioimmunotherapy

scientific article published on 09 April 2019

Underscoring the influence of inorganic chemistry on nuclear imaging with radiometals

scientific article

Understanding the In Vivo Fate of Radioimmunoconjugates for PET and SPECT.

scientific article published on 17 April 2018

Unexpected oxidative C-C cleavage in the metallation of 2-substituted imidazolium salts to give N-heterocyclic carbene complexes.

scientific article published on 25 August 2004

What a difference a carbon makes: H₄octapa vs H₄C3octapa, ligands for In-111 and Lu-177 radiochemistry

scientific article published on 5 September 2014

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