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List of works by Matthias Lütolf

3D Inkjet Printing of Complex, Cell-Laden Hydrogel Structures

scientific article published in Scientific Reports

3D chemical characterization of frozen hydrated hydrogels using ToF-SIMS with argon cluster sputter depth profiling

scientific article published on 7 June 2015

3D reconstitution of the patterned neural tube from embryonic stem cells.

scientific article

A Single Metabolite which Modulates Lipid Metabolism Alters Hematopoietic Stem/Progenitor Cell Behavior and Promotes Lymphoid Reconstitution

scientific article published on 12 August 2020

A generic strategy for pharmacological caging of growth factors for tissue engineering.

scientific article published in July 2013

A high-capacity cell macroencapsulation system supporting the long-term survival of genetically engineered allogeneic cells.

scientific article published on 5 October 2013

A versatile approach to engineering biomolecule-presenting cellular microenvironments.

scientific article published on 7 November 2012

An engineered multicellular stem cell niche for the 3D derivation of human myogenic progenitors from iPSCs

scientific article published on 15 June 2022

Anteroposterior polarity and elongation in the absence of extra-embryonic tissues and of spatially localised signalling in gastruloids: mammalian embryonic organoids

scientific article published on 26 September 2017

Antiangiogenic immunotherapy suppresses desmoplastic and chemoresistant intestinal tumors in mice

scientific article published on 01 March 2020

Artificial Stem Cell Niches ⬇️

scientific article published on September 4, 2009

Artificial niche microarrays for identifying extrinsic cell-fate determinants

scientific article published on 20 July 2018

Artificial niche microarrays for probing single stem cell fate in high throughput

scientific article published on 09 October 2011

Artificial three-dimensional niches deconstruct pancreas development in vitro.

scientific article

Automated analysis of single stem cells in microfluidic traps

scientific article published on 31 May 2012

Bioengineered 3D platform to explore cell-ECM interactions and drug resistance of epithelial ovarian cancer cells

scientific article published on 14 August 2010

Bioengineering approaches to guide stem cell-based organogenesis

scientific article published on May 2014

Bioinspired Hydrogels for 3D Organoid Culture

scientific article published on 01 February 2019

Biomaterials approaches in stem cell mechanobiology

scientific article published on January 2014

Biomaterials meet microfluidics: building the next generation of artificial niches

scientific article published on 05 August 2011

Biomaterials: Spotlight on hydrogels

scientific article published on 01 June 2009

Biomimetic PEG hydrogels crosslinked with minimal plasmin-sensitive tri-amino acid peptides

scientific article published in June 2010

Biomimetic hydrogels for controlled biomolecule delivery to augment bone regeneration.

scientific article published on 20 March 2012

Biomolecular hydrogels formed and degraded via site-specific enzymatic reactions

scientific article published on 21 September 2007

Biopolymeric delivery matrices for angiogenic growth factors.

scientific article published on November 2003

Bovine primary chondrocyte culture in synthetic matrix metalloproteinase-sensitive poly(ethylene glycol)-based hydrogels as a scaffold for cartilage repair

scientific article published in March 2004

Brief Report: Single-Cell Analysis Reveals Cell Division-Independent Emergence of Megakaryocytes From Phenotypic Hematopoietic Stem Cells

scientific article published on 17 July 2015

Capturing Cardiogenesis in Gastruloids

scientific article published on 04 November 2020

Cell specific ingrowth hydrogels

scientific article published on 15 June 2013

Cell-Instructive Microgels with Tailor-Made Physicochemical Properties

scientific article published on 9 September 2015

Cell-demanded release of VEGF from synthetic, biointeractive cell ingrowth matrices for vascularized tissue growth

scientific article published on 16 October 2003

Chronic inflammation imposes aberrant cell fate in regenerating epithelia through mechanotransduction.

scientific article published on 21 December 2015

Controlled breast cancer microarrays for the deconvolution of cellular multilayering and density effects upon drug responses

scientific article

Decoding of position in the developing neural tube from antiparallel morphogen gradients.

scientific article

Defined three-dimensional microenvironments boost induction of pluripotency.

scientific article

Designer matrices for intestinal stem cell and organoid culture

scientific article published on 16 November 2016

Designing materials to direct stem-cell fate

scientific article

Development of bioactive hydrogel capsules for the 3D expansion of pluripotent stem cells in bioreactors

scientific article published on 01 October 2013

Developmental dynamics of the neural crest-mesenchymal axis in creating the thymic microenvironment

scientific article published on 13 May 2022

Diagnostic microchip to assay 3D colony-growth potential of captured circulating tumor cells ⬇️

scientific article published on May 8, 2012

Drug discovery through stem cell-based organoid models

scientific article published on 26 February 2014

Editorial overview: Tissue, cell and pathway engineering: The advent of complexity

scientific article published on 7 September 2017

Engineered signaling centers for the spatially controlled patterning of human pluripotent stem cells

scientific article published on 27 June 2019

Engineering 3D cell instructive microenvironments by rational assembly of artificial extracellular matrices and cell patterning

scientific article published on 10 October 2011

Engineering Stem Cell Self-organization to Build Better Organoids

scientific article published on 01 June 2019

Enhancing the reliability and throughput of neurosphere culture on hydrogel microwell arrays

scientific article published on 31 July 2008

Enzymatic formation of modular cell-instructive fibrin analogs for tissue engineering.

scientific article

Erratum to: Generation of Induced Pluripotent Stem Cells in Defined Three-Dimensional Hydrogels

scientific article published in January 2017

Extracellular matrix bioengineering and systems biology approaches in liver disease ⬇️

scientific article published on June 17, 2011

Fabrication of PEG Hydrogel Microwell Arrays for High-Throughput Single Stem Cell Culture and Analysis ⬇️

scientific article published on January 1, 2012

Gastruloids develop the three body axes in the absence of extraembryonic tissues and spatially localised signalling

Generation of Induced Pluripotent Stem Cells in Defined Three-Dimensional Hydrogels

scientific article published in January 2017

Heparin-binding domain of fibrin(ogen) binds growth factors and promotes tissue repair when incorporated within a synthetic matrix

scientific article published on 4 March 2013

High-throughput approaches for the analysis of extrinsic regulators of stem cell fate ⬇️

scientific article published on January 31, 2012

High-throughput automated organoid culture via stem-cell aggregation in microcavity arrays

scientific article published on 08 June 2020

High-throughput clonal analysis of neural stem cells in microarrayed artificial niches ⬇️

scientific article published on February 6, 2012

High-throughput methods to define complex stem cell niches

scientific article published on April 2010

High-throughput stem cell-based phenotypic screening through microniches

scientific article published on 01 July 2019

Homeostatic mini-intestines through scaffold-guided organoid morphogenesis

scientific article published on 16 September 2020

Hyaluronic Acid Hydrogels Formed in Situ by Transglutaminase-Catalyzed Reaction

scientific article

Hydrogel Microwell Arrays Allow the Assessment of Protease-Associated Enhancement of Cancer Cell Aggregation and Survival.

scientific article

Hydrogel-based milliwell arrays for standardized and scalable retinal organoid cultures

scientific article published on 24 June 2020

Identification of in vitro HSC fate regulators by differential lipid raft clustering

scientific article published on 15 April 2012

In Situ Patterning of Microfluidic Networks in 3D Cell-Laden Hydrogels

scientific article

In Vivo Pre-Instructed HSCs Robustly Execute Asymmetric Cell Divisions In Vitro

scientific article published on 03 November 2020

In situ cell manipulation through enzymatic hydrogel photopatterning.

scientific article

In vitro platforms for tissue engineering: implications for basic research and clinical translation

scientific article published on 24 February 2011

Integration column: artificial ECM: expanding the cell biology toolbox in 3D

scientific article published on 16 February 2009

Integration column: microwell arrays for mammalian cell culture

article

Label-Free Quantification Proteomics for the Identification of Mesenchymal Stromal Cell Matrisome Inside 3D Poly(Ethylene Glycol) Hydrogels

scientific article published on 27 September 2018

Live mammalian cell arrays

scientific article published on 5 May 2013

Machine Learning of Hematopoietic Stem Cell Divisions from Paired Daughter Cell Expression Profiles Reveals Effects of Aging on Self-Renewal

scientific article published on 02 December 2020

Materials science: Cell environments programmed with light

scientific article published on 22 February 2012

Mechano-modulatory synthetic niches for liver organoid derivation

scientific article published on 10 July 2020

Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis

scientific article published on 2 December 2012

Microdrop Printing of Hydrogel Bioinks into 3D Tissue‐Like Geometries ⬇️

scientific article published on December 12, 2011

Microfluidic patterning of protein gradients on biomimetic hydrogel substrates

scientific article published in January 2014

Microfluidic synthesis of cell-type-specific artificial extracellular matrix hydrogels

scientific article published on March 8, 2013

Micropatterning of hydrogels by soft embossing

scientific article published on 01 August 2009

Microscale patterning of hydrogel stiffness through light-triggered uncaging of thiols

scientific article published on 04 September 2014

Morphogenesis Guided by 3D Patterning of Growth Factors in Biological Matrices

scientific article published on 11 May 2020

Multi-axial self-organization properties of mouse embryonic stem cells into gastruloids

scientific article published in Nature

Multiscale microenvironmental perturbation of pluripotent stem cell fate and self-organization

scientific article published on 17 March 2017

NAD⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice

scientific article

Neural tube morphogenesis in synthetic 3D microenvironments

scientific article published on 14 October 2016

Optimization of microfluidic single cell trapping for long-term on-chip culture

scientific article published on 13 January 2010

Patterning of cell-instructive hydrogels by hydrodynamic flow focusing

scientific article published in June 2013

Perturbation of single hematopoietic stem cell fates in artificial niches

scientific article

Pharmacological Induction of a Progenitor State for the Efficient Expansion of Primary Human Hepatocytes

scientific article published on 14 February 2019

Phosphopantetheinyl transferase-catalyzed formation of bioactive hydrogels for tissue engineering.

scientific article published in May 2010

Predicting stem cell fate changes by differential cell cycle progression patterns ⬇️

scientific article published on November 28, 2012

Programmable microfluidic patterning of protein gradients on hydrogels

scientific article published on 08 September 2010

Progress and potential in organoid research

scientific article published on 01 November 2018

Recapitulating macro-scale tissue self-organization through organoid bioprinting

scientific article published on 21 September 2020

Reconstitution of a Patterned Neural Tube from Single Mouse Embryonic Stem Cells.

scientific article published in January 2017

Repair of bone defects using synthetic mimetics of collagenous extracellular matrices

scientific article published on 21 April 2003

Single-cell analyses identify bioengineered niches for enhanced maintenance of hematopoietic stem cells.

scientific article published on 9 August 2017

Smart Hydrogels for the Augmentation of Bone Regeneration by Endogenous Mesenchymal Progenitor Cell Recruitment

scientific article published on 05 February 2020

Sorting live stem cells based on Sox2 mRNA expression

scientific article

Specification of haematopoietic stem cell fate via modulation of mitochondrial activity

scientific article published on 12 October 2016

Stem cell niche engineering through droplet microfluidics

scientific article published on 03 June 2015

Stem cell-materials interactions

scientific article published on 23 September 2014

Stem-cell-based embryo models for fundamental research and translation

scientific article published on 16 November 2020

Synthesis and characterization of well-defined hydrogel matrices and their application to intestinal stem cell and organoid culture.

scientific article

Synthetic 3D PEG-Anisogel Tailored with Fibronectin Fragments Induce Aligned Nerve Extension

scientific article published on 31 October 2019

Tailoring hydrogel degradation and drug release via neighboring amino acid controlled esterhydrolysis

The Effect of Thiol Structure on Allyl Sulfide Photodegradable Hydrogels and their Application as a Degradable Scaffold for Organoid Passaging

scientific article published on 17 June 2020

The NAD-Booster Nicotinamide Riboside Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance

scientific article published on 01 March 2019

The effect of matrix characteristics on fibroblast proliferation in 3D gels

scientific article published on 03 August 2010

The heparin binding domain of von Willebrand factor binds to growth factors and promotes angiogenesis in wound healing

scientific article published on 11 April 2019

The hope and the hype of organoid research.

scientific article published on March 2017

Three-dimensional extracellular matrix-directed cardioprogenitor differentiation: systematic modulation of a synthetic cell-responsive PEG-hydrogel

scientific article

Tissue-Engineering the Intestine: The Trials before the Trials

scientific article published on 01 June 2019

Ultra-rapid prototyping of flexible, multi-layered microfluidic devices via razor writing

scientific article published in January 2015

Understanding the Mechanobiology of Early Mammalian Development through Bioengineered Models

scientific article published on 01 March 2019

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