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List of works by Koji Eto

A chemical probe that labels human pluripotent stem cells

scientific article

A β1-tubulin-based megakaryocyte maturation reporter system identifies novel drugs that promote platelet production

scientific article published on 01 September 2018

Adipose Natural Regulatory B Cells Negatively Control Adipose Tissue Inflammation.

scientific article

Application of ex vivo flow chamber system for assessment of stent thrombosis

scientific article (publication date: August 2002)

Characterization of mesenchymal progenitor cells in the crown and root pulp of primary teeth.

scientific article published in January 2015

Congenital amegakaryocytic thrombocytopenia iPS cells exhibit defective MPL-mediated signaling

scientific article

Cytokine signaling, lipid raft clustering, and HSC hibernation

scientific article published on 18 April 2007

Cytokine signals modulated via lipid rafts mimic niche signals and induce hibernation in hematopoietic stem cells

scientific article published on 20 July 2006

De Novo Mutations Activating Germline TP53 in an Inherited Bone-Marrow-Failure Syndrome

publication published on 23 August 2018

Definitive proof for direct reprogramming of hematopoietic cells to pluripotency.

scientific article

Development of iPS cell-derived blood products and production guidelines

scientific article

Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells

scientific article

Endomucin, a CD34-like sialomucin, marks hematopoietic stem cells throughout development

scientific article published on 28 November 2005

Epigenetic traits inscribed in chromatin accessibility in aged hematopoietic stem cells

scientific article published on 16 May 2022

Ex vivo generation of platelet products from human iPS cells

scientific article published on 01 December 2020

Expandable megakaryocyte cell lines enable clinically applicable generation of platelets from human induced pluripotent stem cells

scientific article

Functional significance of adenosine 5'-diphosphate receptor (P2Y(12)) in platelet activation initiated by binding of von Willebrand factor to platelet GP Ibalpha induced by conditions of high shear rate

scientific article published in May 2002

Generation and manipulation of human iPSC-derived platelets ⬇️

Generation of Col2a1-EGFP iPS cells for monitoring chondrogenic differentiation

scientific article

Generation of functional platelets from human embryonic stem cells in vitro via ES-sacs, VEGF-promoted structures that concentrate hematopoietic progenitors

scientific article published on 03 April 2008

Generation of induced pluripotent stem cells derived from primary and secondary myelofibrosis patient samples

scientific article published on 20 May 2014

Generation of induced pluripotent stem cells from primary chronic myelogenous leukemia patient samples

scientific article published on 16 May 2012

Genetic marking of hematopoietic stem and endothelial cells: identification of the Tmtsp gene encoding a novel cell surface protein with the thrombospondin-1 domain

scientific journal article

Growth and maturation of megakaryocytes is regulated by Lnk/Sh2b3 adaptor protein through crosstalk between cytokine- and integrin-mediated signals

scientific article

Heterozygous ITGA2B R995W mutation inducing constitutive activation of the αIIbβ3 receptor affects proplatelet formation and causes congenital macrothrombocytopenia

scientific article

Hyaline cartilage formation and tumorigenesis of implanted tissues derived from human induced pluripotent stem cells

scientific article

IL-1α induces thrombopoiesis through megakaryocyte rupture in response to acute platelet needs

scientific article

Immortalization of erythroblasts by c-MYC and BCL-XL enables large-scale erythrocyte production from human pluripotent stem cells

scientific article

In Vitro Generation of Megakaryocytes and Platelets from Human Embryonic Stem Cells and Induced Pluripotent Stem Cells ⬇️

scientific article published on 01 January 2012

In vivo imaging visualizes discoid platelet aggregations without endothelium disruption and implicates contribution of inflammatory cytokine and integrin signaling

scientific article

Integrin-αvβ3 regulates thrombopoietin-mediated maintenance of hematopoietic stem cells ⬇️

scientific article published on November 16, 2011

Linkage between the mechanisms of thrombocytopenia and thrombopoiesis

scientific article

Lnk negatively regulates self-renewal of hematopoietic stem cells by modifying thrombopoietin-mediated signal transduction

scientific article

Lnk regulates integrin alphaIIbbeta3 outside-in signaling in mouse platelets, leading to stabilization of thrombus development in vivo

scientific article

Metalloproteinase regulation improves in vitro generation of efficacious platelets from mouse embryonic stem cells

scientific article

Multicolor staining of globin subtypes reveals impaired globin switching during erythropoiesis in human pluripotent stem cells

scientific article published on 29 May 2014

Nov/CCN3 regulates long-term repopulating activity of murine hematopoietic stem cells via integrin αvβ3

scientific article published on 22 February 2014

Novel TPO receptor agonist TA-316 contributes to platelet biogenesis from human iPS cells

scientific article published on 28 February 2017

PKA/CREB Signaling Triggers Initiation of Endothelial and Hematopoietic Cell Differentiation via Etv2 Induction ⬇️

scientific article published on April 1, 2012

Platelet biogenesis wears silkworm cocoons.

scientific article

Potential usefulness of human iPS cells on the generation of platelets

scientific article published on December 1, 2011

Reduction of N-glycolylneuraminic acid in human induced pluripotent stem cells generated or cultured under feeder- and serum-free defined conditions

scientific article

Relieving Dyrk1a repression of MKL1 confers an adult-like phenotype to human infantile megakaryocytes

scientific article published in 2022

Selective Inhibition of ADAM17 Efficiently Mediates Glycoprotein Ibα Retention During Ex Vivo Generation of Human Induced Pluripotent Stem Cell-Derived Platelets

scientific article published on 5 October 2016

Skewed megakaryopoiesis in human induced pluripotent stem cell-derived haematopoietic progenitor cells harbouring calreticulin mutations

scientific article published on 09 May 2018

Spred1 Safeguards Hematopoietic Homeostasis against Diet-Induced Systemic Stress

scientific article published on 18 April 2018

Stepwise development of hematopoietic stem cells from embryonic stem cells

scientific article

Suppressive effects of anagrelide on cell cycle progression and the maturation of megakaryocyte progenitor cell lines in human induced pluripotent stem cells

scientific article published on 05 September 2019

TGF-beta as a candidate bone marrow niche signal to induce hematopoietic stem cell hibernation

scientific article published on 22 October 2008

TMEM16F is required for phosphatidylserine exposure and microparticle release in activated mouse platelets

scientific article published on 28 September 2015

Ten years of induced pluripotency: from basic mechanisms to therapeutic applications

scientific article

The WAVE2/Abi1 complex differentially regulates megakaryocyte development and spreading: implications for platelet biogenesis and spreading machinery

scientific journal article

The actin polymerization regulator WAVE2 is required for early bone marrow repopulation by hematopoietic stem cells.

scientific article published on May 2009

The generation of induced pluripotent stem cells (iPSCs) from patients with infantile and late-onset types of Pompe disease and the effects of treatment with acid-α-glucosidase in Pompe's iPSCs

scientific article published on 4 March 2014

Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells

scientific article

Turbulence Activates Platelet Biogenesis to Enable Clinical Scale Ex Vivo Production

scientific article published on 12 July 2018

Two differential flows in a bioreactor promoted platelet generation from human pluripotent stem cell–derived megakaryocytes ⬇️

scientific article published on April 22, 2013

Tyrosyl-tRNA synthetase stimulates thrombopoietin-independent hematopoiesis accelerating recovery from thrombocytopenia

article published in the Proceedings of the National Academy of Sciences of the United States of America

[Ex vivo platelet production from induced pluripotent stem cells]

scientific article published on 01 January 2018

[Reconstitution of the hematopoietic system and clinical applications of iPS cells]

scientific article published on 01 January 2019

iPSC-Derived Platelets Depleted of HLA Class I Are Inert to Anti-HLA Class I and Natural Killer Cell Immunity

scientific article published on 26 December 2019

αIIbβ3 changes gears in MKs and platelets

scientific article published on 01 April 2019

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