List of works - Jeffery L Twiss

A HuD-ZBP1 ribonucleoprotein complex localizes GAP-43 mRNA into axons through its 3' untranslated region AU-rich regulatory element.

scientific article

A functional equivalent of endoplasmic reticulum and Golgi in axons for secretion of locally synthesized proteins

scientific article published on 22 October 2008

An Essential Postdevelopmental Role for Lis1 in Mice

scientific article

An age-related sprouting transcriptome provides molecular control of axonal sprouting after stroke.

scientific article

Analysis of protein domains and Rett syndrome mutations indicate that multiple regions influence chromatin-binding dynamics of the chromatin-associated protein MECP2 in vivo

scientific journal article

Axonal G3BP1 stress granule protein limits axonal mRNA translation and nerve regeneration

scientific article published in Nature Communications

Axonal amphoterin mRNA is regulated by translational control and enhances axon outgrowth

scientific article

Axonal degeneration is mediated by the mitochondrial permeability transition pore.

scientific article published on January 2011

Axonal localization of neuritin/CPG15 mRNA in neuronal populations through distinct 5' and 3' UTR elements

scientific article published on August 2013

Axonal localization of neuritin/CPG15 mRNA is limited by competition for HuD binding

scientific article published on 4 September 2017

Axonal mRNA transport and translation at a glance.

scientific article published on 13 April 2018

Axonal transcription factors signal retrogradely in lesioned peripheral nerve

scientific article published on 13 January 2012

Axonal transport of neural membrane protein 35 mRNA increases axon growth

scientific article published on 24 October 2012

Axonally synthesized β-actin and GAP-43 proteins support distinct modes of axonal growth

scientific article published on February 2013

Calcium release from intra-axonal endoplasmic reticulum leads to axon degeneration through mitochondrial dysfunction

scientific article

Competing Interactions of RNA-Binding Proteins, MicroRNAs, and Their Targets Control Neuronal Development and Function

scientific article

Conserved 3'-untranslated region sequences direct subcellular localization of chaperone protein mRNAs in neurons.

scientific article

Deacetylation of Miro1 by HDAC6 blocks mitochondrial transport and mediates axon growth inhibition

scientific article published on 08 May 2019

Dendritic localization of the RNA-binding protein HuD in hippocampal neurons: association with polysomes and upregulation during contextual learning

scientific journal article

Differential transport and local translation of cytoskeletal, injury-response, and neurodegeneration protein mRNAs in axons

scientific journal article

Dynamic Changes in Local Protein Synthetic Machinery in Regenerating Central Nervous System Axons after Spinal Cord Injury

scientific article published on 07 June 2016

Dynamics of axonal mRNA transport and implications for peripheral nerve regeneration

scientific article

Exercise dependent increase in axon regeneration into peripheral nerve grafts by propriospinal but not sensory neurons after spinal cord injury is associated with modulation of regeneration-associated genes.

scientific article

Extracellular stimuli specifically regulate localized levels of individual neuronal mRNAs.

scientific article

HDAC6 is a target for protection and regeneration following injury in the nervous system

scientific article

IB4-binding sensory neurons in the adult rat express a novel 3' UTR-extended isoform of CaMK4 that is associated with its localization to axons

scientific article published on February 2014

Interaction of survival of motor neuron (SMN) and HuD proteins with mRNA cpg15 rescues motor neuron axonal deficits.

scientific article

Isolation and analyses of axonal ribonucleoprotein complexes

scientific article published on 02 September 2015

KSRP modulation of GAP-43 mRNA stability restricts axonal outgrowth in embryonic hippocampal neurons.

scientific article

Localized IRES-dependent translation of ER chaperone protein mRNA in sensory axons

scientific article

Localized regulation of axonal RanGTPase controls retrograde injury signaling in peripheral nerve

scientific article

Locally translated mTOR controls axonal local translation in nerve injury.

scientific article published in March 2018

Lysophosphatidic acid differentially regulates axonal mRNA translation through 5'UTR elements

scientific article

Mechanism and role of the intra-axonal Calreticulin translation in response to axonal injury

scientific article published on 25 October 2019

Mitochondria coordinate sites of axon branching through localized intra-axonal protein synthesis

scientific article published on 12 December 2013

Molecular determinants of the axonal mRNA transcriptome

scientific article published on 07 October 2013

Na,K-ATPase beta1-subunit increases the translation efficiency of the alpha1-subunit in MSV-MDCK cells

scientific article published on 7 May 2004

Neural Progenitor Cells Promote Axonal Growth and Alter Axonal mRNA Localization in Adult Neurons.

scientific article published on January 2017

Neuroproteomics: How Many Angels can be Identified in an Extract from the Head of a Pin?

scientific article published on 4 January 2016

New insights into neuronal regeneration: the role of axonal protein synthesis in pathfinding and axonal extension

scientific article

Nucleolin-Mediated RNA Localization Regulates Neuron Growth and Cycling Cell Size

scientific article published on 27 July 2016

Old dogs with new tricks: intra-axonal translation of nuclear proteins

scientific article

PC12 cells regulate inducible cyclic AMP (cAMP) element repressor expression to differentially control cAMP response element-dependent transcription in response to nerve growth factor and cAMP.

scientific article published on 24 October 2006

PI(3,5)P2 biosynthesis regulates oligodendrocyte differentiation by intrinsic and extrinsic mechanisms

scientific article published on 23 March 2016

Pathophysiological mechanisms for actions of the neurotrophins

scientific article published on October 2006

Peripheral nerve axons contain machinery for co-translational secretion of axonally-generated proteins

scientific article published on 9 July 2013

Profiling Axonal mRNA Transport ⬇️

scientific article published on January 1, 2011

RNA exodus to Israel: RNA controlling function in the far reaches of the neuron. Workshop on RNA control on neuronal function

scientific article

RNA transport and localized protein synthesis in neurological disorders and neural repair

scientific article published on August 2007

Regulation of mRNA transport and translation in axons

scientific article published on January 2009

Regulation of protein levels in subcellular domains through mRNA transport and localized translation

scientific article

Repression of Na,K-ATPase beta1-subunit by the transcription factor snail in carcinoma

scientific article published on 29 December 2003

Ribosomes in axons--scrounging from the neighbors?

scientific article published on 08 April 2009

SUMO-Modification of the La Protein Facilitates Binding to mRNA In Vitro and in Cells

scientific article

Subcellular communication through RNA transport and localized protein synthesis

scientific article published on 07 October 2010

Subcellular knockout of importin β1 perturbs axonal retrograde signaling

scientific article

Sumoylation in axons triggers retrograde transport of the RNA-binding protein La.

scholarly article

The evolving roles of axonally synthesized proteins in regeneration

scientific article

The functional organization of axonal mRNA transport and translation

scientific article published on 07 December 2020

The glycine arginine-rich domain of the RNA-binding protein nucleolin regulates its subcellular localization

scientific article published on 13 September 2021

The road not taken: new destinations for yeast mRNAs on the move

scientific article published on 31 August 2011

Tracking in the Wlds--the hunting of the SIRT and the luring of the Draper

scientific article published on June 2006

Voluntary exercise increases axonal regeneration from sensory neurons

scholarly article

hnRNPs Interacting with mRNA Localization Motifs Define Axonal RNA Regulons

scientific article published on 23 July 2018

mRNAs and Protein Synthetic Machinery Localize into Regenerating Spinal Cord Axons When They Are Provided a Substrate That Supports Growth

scientific article published in July 2015

List of works by Jeffery L Twiss

A HuD-ZBP1 ribonucleoprotein complex localizes GAP-43 mRNA into axons through its 3' untranslated region AU-rich regulatory element.

A functional equivalent of endoplasmic reticulum and Golgi in axons for secretion of locally synthesized proteins

An Essential Postdevelopmental Role for Lis1 in Mice

An age-related sprouting transcriptome provides molecular control of axonal sprouting after stroke.

Analysis of protein domains and Rett syndrome mutations indicate that multiple regions influence chromatin-binding dynamics of the chromatin-associated protein MECP2 in vivo

Axonal G3BP1 stress granule protein limits axonal mRNA translation and nerve regeneration

Axonal amphoterin mRNA is regulated by translational control and enhances axon outgrowth

Axonal degeneration is mediated by the mitochondrial permeability transition pore.

Axonal localization of neuritin/CPG15 mRNA in neuronal populations through distinct 5' and 3' UTR elements

Axonal localization of neuritin/CPG15 mRNA is limited by competition for HuD binding

Axonal mRNA transport and translation at a glance.

Axonal transcription factors signal retrogradely in lesioned peripheral nerve

Axonal transport of neural membrane protein 35 mRNA increases axon growth

Axonally synthesized β-actin and GAP-43 proteins support distinct modes of axonal growth

Calcium release from intra-axonal endoplasmic reticulum leads to axon degeneration through mitochondrial dysfunction

Competing Interactions of RNA-Binding Proteins, MicroRNAs, and Their Targets Control Neuronal Development and Function

Conserved 3'-untranslated region sequences direct subcellular localization of chaperone protein mRNAs in neurons.

Deacetylation of Miro1 by HDAC6 blocks mitochondrial transport and mediates axon growth inhibition

Dendritic localization of the RNA-binding protein HuD in hippocampal neurons: association with polysomes and upregulation during contextual learning

Differential transport and local translation of cytoskeletal, injury-response, and neurodegeneration protein mRNAs in axons

Dynamic Changes in Local Protein Synthetic Machinery in Regenerating Central Nervous System Axons after Spinal Cord Injury

Dynamics of axonal mRNA transport and implications for peripheral nerve regeneration

Exercise dependent increase in axon regeneration into peripheral nerve grafts by propriospinal but not sensory neurons after spinal cord injury is associated with modulation of regeneration-associated genes.

Extracellular stimuli specifically regulate localized levels of individual neuronal mRNAs.

HDAC6 is a target for protection and regeneration following injury in the nervous system

IB4-binding sensory neurons in the adult rat express a novel 3' UTR-extended isoform of CaMK4 that is associated with its localization to axons

Interaction of survival of motor neuron (SMN) and HuD proteins with mRNA cpg15 rescues motor neuron axonal deficits.

Isolation and analyses of axonal ribonucleoprotein complexes

KSRP modulation of GAP-43 mRNA stability restricts axonal outgrowth in embryonic hippocampal neurons.

Localized IRES-dependent translation of ER chaperone protein mRNA in sensory axons

Localized regulation of axonal RanGTPase controls retrograde injury signaling in peripheral nerve

Locally translated mTOR controls axonal local translation in nerve injury.

Lysophosphatidic acid differentially regulates axonal mRNA translation through 5'UTR elements

Mechanism and role of the intra-axonal Calreticulin translation in response to axonal injury

Mitochondria coordinate sites of axon branching through localized intra-axonal protein synthesis

Molecular determinants of the axonal mRNA transcriptome

Na,K-ATPase beta1-subunit increases the translation efficiency of the alpha1-subunit in MSV-MDCK cells

Neural Progenitor Cells Promote Axonal Growth and Alter Axonal mRNA Localization in Adult Neurons.

Neuroproteomics: How Many Angels can be Identified in an Extract from the Head of a Pin?

New insights into neuronal regeneration: the role of axonal protein synthesis in pathfinding and axonal extension

Nucleolin-Mediated RNA Localization Regulates Neuron Growth and Cycling Cell Size

Old dogs with new tricks: intra-axonal translation of nuclear proteins

PC12 cells regulate inducible cyclic AMP (cAMP) element repressor expression to differentially control cAMP response element-dependent transcription in response to nerve growth factor and cAMP.

PI(3,5)P2 biosynthesis regulates oligodendrocyte differentiation by intrinsic and extrinsic mechanisms

Pathophysiological mechanisms for actions of the neurotrophins

Peripheral nerve axons contain machinery for co-translational secretion of axonally-generated proteins

Profiling Axonal mRNA Transport ⬇️

RNA exodus to Israel: RNA controlling function in the far reaches of the neuron. Workshop on RNA control on neuronal function

RNA transport and localized protein synthesis in neurological disorders and neural repair

Regulation of mRNA transport and translation in axons

Regulation of protein levels in subcellular domains through mRNA transport and localized translation

Repression of Na,K-ATPase beta1-subunit by the transcription factor snail in carcinoma

Ribosomes in axons--scrounging from the neighbors?

SUMO-Modification of the La Protein Facilitates Binding to mRNA In Vitro and in Cells

Subcellular communication through RNA transport and localized protein synthesis

Subcellular knockout of importin β1 perturbs axonal retrograde signaling

Sumoylation in axons triggers retrograde transport of the RNA-binding protein La.

The evolving roles of axonally synthesized proteins in regeneration

The functional organization of axonal mRNA transport and translation

The glycine arginine-rich domain of the RNA-binding protein nucleolin regulates its subcellular localization

The road not taken: new destinations for yeast mRNAs on the move

Tracking in the Wlds--the hunting of the SIRT and the luring of the Draper

Voluntary exercise increases axonal regeneration from sensory neurons

hnRNPs Interacting with mRNA Localization Motifs Define Axonal RNA Regulons

mRNAs and Protein Synthetic Machinery Localize into Regenerating Spinal Cord Axons When They Are Provided a Substrate That Supports Growth