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List of works by Shixuan Wang

A Potent Oncolytic Adenovirus Selectively Blocks the STAT3 Signaling Pathway and Potentiates Cisplatin Antitumor Activity in Ovarian Cancer ⬇️

scientific article published on October 14, 2011

A genome-wide association study identifies two new cervical cancer susceptibility loci at 4q12 and 17q12

scientific journal article

A novel "priming-boosting" strategy for immune interventions in cervical cancer

scientific article published on 6 January 2015

A novel oncolytic adenovirus selectively silences the expression of tumor-associated STAT3 and exhibits potent antitumoral activity

scientific article published on December 2009

A systematic comparison of the anti-tumoural activity and toxicity of the three Adv-TKs

scientific article

Abrogation of constitutive Stat3 activity circumvents cisplatin resistant ovarian cancer

scientific article published on 17 August 2013

Activation of fibronectin/PI-3K/Akt2 leads to chemoresistance to docetaxel by regulating survivin protein expression in ovarian and breast cancer cells

scientific article published on 2 January 2008

Adeno-associated Virus-mediated Local Delivery of LIGHT Suppresses Tumorigenesis in a Murine Cervical Cancer Model ⬇️

scientific article published on October 1, 2011

Adjuvant adenovirus-mediated delivery of herpes simplex virus thymidine kinase administration improves outcome of liver transplantation in patients with advanced hepatocellular carcinoma

scientific article published in October 2007

Adjuvant chemotherapy after surgery can improve clinical outcomes for patients with IB2-IIB cervical cancer with neoadjuvant chemotherapy followed by radical surgery.

scientific article published on 24 April 2018

Adjuvant chemotherapy, a valuable alternative option in selected patients with cervical cancer

scientific article

Anti-Tumor Effects of the Peptide TMTP1-GG-D(KLAKLAK)2 on Highly Metastatic Cancers ⬇️

scientific article published on September 11, 2012

Antisense Ki-67 cDNA transfection reverses the tumorigenicity and induces apoptosis in human breast cancer cells

scientific article published on October 2008

Antisense targeting human papillomavirus type 16 E6 and E7 genes contributes to apoptosis and senescence in SiHa cervical carcinoma cells

scientific article

Antisense-Snail transfer inhibits tumor metastasis by inducing E-cadherin expression.

scientific article

Association of 42 SNPs with genetic risk for cervical cancer: an extensive meta-analysis

scientific article published on 15 April 2015

Association of an oestrogen receptor gene polymorphism in Chinese Han women with endometriosis and endometriosis-related infertility ⬇️

scientific article published on September 22, 2012

Biliverdin reductase mediates hypoxia-induced EMT via PI3-kinase and Akt

scientific article published on 9 January 2008

Biodistribution and kinetics of the novel selective oncolytic adenovirus M1 after systemic administration

scientific article published in June 2008

C4orf7 contributes to ovarian cancer metastasis by promoting cancer cell migration and invasion.

scientific article

Changes in prevalence and clinical characteristics of cervical cancer in the People's Republic of China: a study of 10,012 cases from a nationwide working group

scientific article published on 16 September 2013

Changes of endocrine and ultrasound markers as ovarian aging in modifying the Stages of Reproductive Aging Workshop (STRAW) staging system with subclassification of mid reproductive age stage ⬇️

scientific article published on July 25, 2012

Cisplatin-induced senescence in ovarian cancer cells is mediated by GRP78.

scientific article published on 23 April 2014

Clinicopathological Significance of VEGF-C, VEGFR-3 and Cyclooxygenase-2 in Early-Stage Cervical Cancer ⬇️

scientific article published on March 1, 2008

Comparative genomics and function analysis on BI1 family

scientific article

Correction: A Systematic Comparison of the Anti-Tumoural Activity and Toxicity of the Three Adv-TKs

scientific article published on 7 April 2016

Correlation of TWIST2 up-regulation and epithelial-mesenchymal transition during tumorigenesis and progression of cervical carcinoma

scientific article published on 22 October 2011

Cytoplasmic p21 is a potential predictor for cisplatin sensitivity in ovarian cancer

scientific article

DT390-triTMTP1, a Novel Fusion Protein of Diphtheria Toxin with Tandem Repeat TMTP1 Peptide, Preferentially Targets Metastatic Tumors ⬇️

scientific article published on November 30, 2012

Deletion of the intracellular domain of coxsackie and adenovirus receptor (CAR) enhances the expression of itself and boosts the efficiency of current adenovirus-mediated gene therapy in ovarian cancer cell lines in vitro

scientific article published on 12 December 2006

Development and characterization of a novel method for the analysis of gene expression patterns in lymphatic endothelial cells derived from primary breast tissues

scientific article

Development and characterization of a novel method to analyze global gene expression profiles in endothelial cells derived from primary tissues

scientific article

Development and validation of a surgical-pathologic staging and scoring system for cervical cancer

scientific article published on 21 March 2016

Development of Criteria for Ovarian Preservation in Cervical Cancer Patients Treated with Radical Surgery With or Without Neoadjuvant Chemotherapy: A Multicenter Retrospective Study and Meta-analysis ⬇️

scientific article published on October 3, 2012

Dominant contribution of malignant endothelial cells to endotheliopoiesis in chronic myeloid leukemia

scientific article published on 25 October 2008

Down-regulation of MT1-MMP expression suppresses tumor cell invasion in metastatic human SW626 ovarian cancer cells.

scientific article published on February 2006

Early response to neoadjuvant chemotherapy can help predict long-term survival in patients with cervical cancer

scientific article published on 20 August 2016

Effect of Mad2 on paclitaxel-induced cell death in ovarian cancer cells ⬇️

scientific article published on November 10, 2010

Effect of lung resistance-related protein on the resistance to cisplatin in human ovarian cancer cell lines

scientific article

Effect of spindle checkpoint on Akt2-mediated paclitaxel-resistance in A2780 ovarian cancer cells

scientific article

Effect of the cyclin-dependent kinases inhibitor p27 on resistance of ovarian cancer multicellular spheroids to anticancer chemotherapy

scientific article published on 28 May 2005

Effect of tumor suppressor gene PTEN on the resistance to cisplatin in human ovarian cancer cell lines and related mechanisms

scientific article

Effects of human papillomavirus type 16 E7 protein on the growth of cervical carcinoma cells and immuno-escape through the TGF-beta1 signaling pathway

scientific article published on 2 November 2005

Enhanced in vitro invasiveness of ovarian cancer cells through up-regulation of VEGF and induction of MMP-2.

scientific article published on April 2006

Enhanced targeted anticancer effects and inhibition of tumor metastasis by the TMTP1 compound peptide TMTP1-TAT-NBD.

scientific article published on 11 May 2012

Essential role of c-Jun-NH2-terminal kinase on synergy induction of apoptosis by TRAIL plus ADM in ADM resistant MCF-7/ADM cells

scientific article published on July 2006

Evaluation of (99m)Tc-HYNIC-TMTP1 as a tumor-homing imaging agent targeting metastasis with SPECT.

scientific article published on 13 November 2014

Expression of Pin1 and Ki67 in cervical cancer and their significance

scientific article published on 01 January 2006

Expression of TMEM87B interacting with the human papillomavirus type 18 E6 oncogene in the Hela cDNA library by a yeast two-hybrid system.

scientific article

Ezrin silencing by small hairpin RNA reverses metastatic behaviors of human breast cancer cells

scientific article published on 26 December 2007

Fibronectin-mediated activation of Akt2 protects human ovarian and breast cancer cells from docetaxel-induced apoptosis via inhibition of the p38 pathway

scientific article published on February 2008

Genome-wide association study identifies four SNPs associated with response to platinum-based neoadjuvant chemotherapy for cervical cancer

scientific article published on 25 January 2017

Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism

scientific article

HPV16/18 E5, a promising candidate for cervical cancer vaccines, affects SCPs, cell proliferation and cell cycle, and forms a potential network with E6 and E7 ⬇️

scientific article published on October 30, 2012

Heat shock proteins and p53 play a critical role in K+ channel-mediated tumor cell proliferation and apoptosis

scientific article

Human papillomavirus 16/18 E5 promotes cervical cancer cell proliferation, migration and invasion in vitro and accelerates tumor growth in vivo

scientific article published on 26 October 2012

Hypoxia induced paclitaxel resistance in human ovarian cancers via hypoxia-inducible factor 1alpha

scientific article

Hypoxia-inducible factor-1α enhances the malignant phenotype of multicellular spheroid HeLa cells in vitro

scientific article

Identification of LIV1, a putative zinc transporter gene responsible for HDACi-induced apoptosis, using a functional gene screen approach

scientific article

Implication of the Akt2/survivin pathway as a critical target in paclitaxel treatment in human ovarian cancer cells

scientific article

Induction of apoptosis in human ovarian epithelial cancer cells by antisurvivin oligonucleotides.

scientific article published on July 2005

Influence of chk1 and plk1 silencing on radiation- or cisplatin-induced cytotoxicity in human malignant cells

scientific article

Inhibition of Akt signaling by SN-38 induces apoptosis in cervical cancer

scientific article

Inhibition of PC cell-derived growth factor (PCDGF)/granulin-epithelin precursor (GEP) decreased cell proliferation and invasion through downregulation of cyclin D and CDK4 and inactivation of MMP-2

scientific article published on 29 January 2007

Inhibition of motile and invasive properties of ovarian cancer cells by ASODN against Rho-associated protein kinase

scientific article published on January 2005

Inhibition of proliferative and invasive capacities of breast cancer cells by arginine-glycine-aspartic acid peptide in vitro.

scientific article published on January 2006

Isolation and characterization of lymphatic endothelial cells from human glossal lymphangioma.

scientific article published in January 2010

Knock-down of P-glycoprotein reverses taxol resistance in ovarian cancer multicellular spheroids

scientific article published on January 2007

Lymphoma endothelium preferentially expresses Tim-3 and facilitates the progression of lymphoma by mediating immune evasion

scientific article

Matched-case comparison of neoadjuvant chemotherapy in patients with FIGO stage IB1-IIB cervical cancer to establish selection criteria ⬇️

scientific article published on April 13, 2012

Mesenchymal stem cells as carriers and amplifiers in CRAd delivery to tumors ⬇️

scientific article published on November 3, 2011

Multiple pelvic accessory spleen: Rare case report with review of literature

scientific article published on 28 February 2018

Overexpression of vimentin contributes to prostate cancer invasion and metastasis via src regulation

scientific article

Peroxiredoxin 2 inhibits granulosa cell apoptosis during follicle atresia through the NFKB pathway in mice

scientific article published on 19 January 2011

Pin1 contributes to cervical tumorigenesis by regulating cyclin D1 expression

scientific article published on 01 September 2006

Plexin-B1 silencing inhibits ovarian cancer cell migration and invasion ⬇️

scientific article published on November 8, 2010

Primary screening for breast diseases among 17618 women in Wufeng area, a region with high incidence of cervical cancer in China ⬇️

scientific article published on April 20, 2012

Production and verification of human papillomavirus type 18 vaccine in vitro.

scientific article published on July 2008

Prospective cohort study to evaluate the efficacy of taxane plus platinum and CPT-11plus platinum regimes and to identify prognostic risk factors in cervical cancer patients

scientific article

Proteome analysis of human androgen-independent prostate cancer cell lines: variable metastatic potentials correlated with vimentin expression

scientific article

Proteomics analysis of normal and senescent NG108-15 cells: GRP78 plays a negative role in cisplatin-induced senescence in the NG108-15 cell line

scientific article

RNA interference against HPV16 E7 oncogene leads to viral E6 and E7 suppression in cervical cancer cells and apoptosis via upregulation of Rb and p53

scientific article published on 01 February 2008

Reduced expression of Snail decreases breast cancer cell motility by downregulating the expression and inhibiting the activity of RhoA GTPase

scientific article published on 07 June 2013

Regulation of DNA methylation on the expression of the FHIT gene contributes to cervical carcinoma cell tumorigenesis

scientific article

Regulation of HtrA2/Omi by X-linked inhibitor of apoptosis protein in chemoresistance in human ovarian cancer cells

scientific article

Relationship between cytochrome c-mediated caspase-3 activity and chemoresistance in cisplatin-resistant human ovarian cancer cell lines

scientific article

Relationship between the expression of telomerase and human papillomavirus infection in invasive uterine cervical carcinoma

scientific article published on 01 August 2007

Resistance to chemotherapy-induced apoptosis via decreased caspase-3 activity and overexpression of antiapoptotic proteins in ovarian cancer

scientific article published on July 2004

Reversal of the malignant phenotype of cervical cancer CaSki cells through adeno-associated virus-mediated delivery of HPV16 E7 antisense RNA.

scientific article published on April 2006

Reversal of the malignant phenotype of ovarian cancer A2780 cells through transfection with wild-type PTEN gene

scientific article

Reversing chemoresistance in cisplatin-resistant human ovarian cancer cells: a role of c-Jun NH2-terminal kinase 1.

scientific article published on October 2005

Risk model in stage IB1-IIB cervical cancer with positive node after radical hysterectomy

scientific article published on 27 May 2016

Role of hTERT in apoptosis of cervical cancer induced by histone deacetylase inhibitor

scientific article

Screening for novel binding proteins interacting with human papillomavirus type 18 E6 oncogene in the Hela cDNA library by yeast two-hybrid system

scientific article

Selective targeting of HPV-16 E6/E7 in cervical cancer cells with a potent oncolytic adenovirus and its enhanced effect with radiotherapy in vitro and vivo

scientific article

Short hairpin RNA targeting c-FLIP sensitizes human cervical adenocarcinoma Hela cells to chemotherapy and radiotherapy

scientific article published in November 2008

Silencing of the STAT3 signaling pathway reverses the inherent and induced chemoresistance of human ovarian cancer cells ⬇️

scientific article published on May 7, 2013

Soluble B and T lymphocyte attenuator possesses antitumor effects and facilitates heat shock protein 70 vaccine-triggered antitumor immunity against a murine TC-1 cervical cancer model in vivo

scientific article

Suppression of EphB4 improves the inhibitory effect of mTOR shRNA on the biological behaviors of ovarian cancer cells by down-regulating Akt phosphorylation

scientific article

Synergistic Efficacy in Human Ovarian Cancer Cells by Histone Deacetylase Inhibitor TSA and Proteasome Inhibitor PS-341 ⬇️

scientific article published on February 23, 2011

Synergistic Killing Effect between Vorinostat and Target of CD146 in Malignant Cells ⬇️

scientific article published on September 30, 2010

Systematic review and meta-analysis of the prognostic significance of microRNAs in cervical cancer.

scientific article

TALEN-mediated targeting of HPV oncogenes ameliorates HPV-related cervical malignancy

scientific article

TMTP1, a novel tumor-homing peptide specifically targeting metastasis

scientific article

Telmisartan but not valsartan inhibits TGF-beta-mediated accumulation of extracellular matrix via activation of PPARgamma

scientific journal article

The Preparation of Human Papillomavirus Type 58 Vaccine and Exploring Its Biological Activity and Immunogenicity In Vitro ⬇️

scientific article published on August 1, 2011

The effect of RhoA on human umbilical vein endothelial cell migration and angiogenesis in vitro

scientific article published on 01 May 2006

The novel fusion protein sTRAIL-TMTP1 exhibits a targeted inhibition of primary tumors and metastases

scientific article published on 26 October 2013

The nuclear protein expression levels of SNAI1 and ZEB1 are involved in the progression and lymph node metastasis of cervical cancer via the epithelial-mesenchymal transition pathway ⬇️

scientific article published on June 20, 2013

The physical state of HPV16 infection and its clinical significance in cancer precursor lesion and cervical carcinoma

scientific article

The pro-angiogenic factors stimulated by human papillomavirus type 16 E6 and E7 protein in C33A and human fibroblasts

scientific article

The relationship between c-FLIP expression and human papillomavirus E2 gene disruption in cervical carcinogenesis

scientific article published on 12 April 2007

Triggering of death receptor apoptotic signaling by human papillomavirus 16 E2 protein in cervical cancer cell lines is mediated by interaction with c-FLIP ⬇️

scientific article published on January 1, 2011

Twist2, the key Twist isoform related to prognosis, promotes invasion of cervical cancer by inducing epithelial-mesenchymal transition and blocking senescence

scientific article

[Effects of RelA antisense oligonucleotide on apoptosis of ovarian cancer cells COC1]

scientific article published on 01 April 2002

[Role of vascular endothelial growth factor overexpression in ovarian tumor invasion and mechanism]

scientific article published on 01 May 2002

miR-222 is upregulated in epithelial ovarian cancer and promotes cell proliferation by downregulating P27(kip1.)

scientific article published on 13 June 2013

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