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Authors whose works are in public domain in at least one jurisdiction

List of works by Frank Speleman

59-gene prognostic signature sub-stratifies high-risk neuroblastoma patients

article

A brief commentary on "Chromosomal aberrations in neuroblastoma cell lines identified by cross species color banding and chromosome painting"

scientific article published on 01 June 2002

A constitutional translocation t(1;17)(p36.2;q11.2) in a neuroblastoma patient disrupts the human NBPF1 and ACCN1 genes

scientific article

A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL).

scientific article

A detailed inventory of DNA copy number alterations in four commonly used Hodgkin's lymphoma cell lines

scientific article (publication date: July 2007)

A multilocus technique for risk evaluation of patients with neuroblastoma

scientific article published on February 2011

A novel TLX1-driven T-ALL zebrafish model: comparative genomic analysis with other leukemia models

scientific article published on 26 June 2020

A novel and universal method for microRNA RT-qPCR data normalization

scientific article

A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution

scientific article

A p53 drug response signature identifies prognostic genes in high-risk neuroblastoma

scientific article (publication date: 2013)

ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia

scientific article published on 9 October 2014

ALK activation by the CLTC-ALK fusion is a recurrent event in large B-cell lymphoma

scientific article published on 15 May 2003

ALK positively regulates MYCN activity through repression of HBP1 expression

scientific article published on 11 December 2018

Aberrant methylation of candidate tumor suppressor genes in neuroblastoma

scientific article published on 25 September 2008

Aberrant splicing of the PTPRD gene mimics microdeletions identified at this locus in neuroblastomas

scientific article published on March 2008

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

scientific article

Accurate outcome prediction in neuroblastoma across independent data sets using a multigene signature

scientific article

Accurate prediction of neuroblastoma outcome based on miRNA expression profiles

scientific article

Activated Alk triggers prolonged neurogenesis and Ret upregulation providing a therapeutic target in ALK-mutated neuroblastoma

scientific article

Adenovirus-mediated hPNPase(old-35) gene transfer as a therapeutic strategy for neuroblastoma

scientific article

An interstitial deletion of chromosome 7 at band q21: a case report and review

scientific article published in April 2005

Antitumor activity of the selective MDM2 antagonist nutlin-3 against chemoresistant neuroblastoma with wild-type p53.

scientific article

Application of laser capture microdissection in genetic analysis of neuroblastoma and neuroblastoma precursor cells

scientific article

Array comparative genomic hybridization and flow cytometry analysis of spontaneous abortions and mors in utero samples.

scientific article

ArrayCGH-based classification of neuroblastoma into genomic subgroups

scientific article published on December 2007

BET bromodomain protein inhibition is a therapeutic option for medulloblastoma.

scientific article

CADM1 is a strong neuroblastoma candidate gene that maps within a 3.72 Mb critical region of loss on 11q23

scientific article

CASP8 SNP D302H (rs1045485) is associated with worse survival in MYCN-amplified neuroblastoma patients

scientific article

CLL cells respond to B-Cell receptor stimulation with a microRNA/mRNA signature associated with MYC activation and cell cycle progression

scientific article

Cancer gene prioritization for targeted resequencing using FitSNP scores

scientific article

Challenges for CNV interpretation in clinical molecular karyotyping: lessons learned from a 1001 sample experience

scientific article published on 16 September 2009

Characterization of a set of tumor suppressor microRNAs in T cell acute lymphoblastic leukemia

scientific article

Chromosomal and microRNA expression patterns reveal biologically distinct subgroups of 11q- neuroblastoma

scientific article

Chromosome 3p microsatellite allelotyping in neuroblastoma: a report on the technical hurdles

scientific article

Claes Lundsteen—in Memoriam

Clinical significance of HOX11L2 expression linked to t(5;14)(q35;q32), of HOX11 expression, and of SIL-TAL fusion in childhood T-cell malignancies: results of EORTC studies 58881 and 58951

scientific article (publication date: 15 January 2004)

Combined karyotyping, CGH and M-FISH analysis allows detailed characterization of unidentified chromosomal rearrangements in Merkel cell carcinoma

scientific article

Combined subtractive cDNA cloning and array CGH: an efficient approach for identification of overexpressed genes in DNA amplicons

scientific article

Comparison of miRNA profiles of microdissected Hodgkin/Reed-Sternberg cells and Hodgkin cell lines versus CD77+ B-cells reveals a distinct subset of differentially expressed miRNAs

scientific article published on 22 September 2009

Comprehensive NF1 screening on cultured Schwann cells from neurofibromas

scientific article published in October 2006

Comprehensive analysis of transcriptome variation uncovers known and novel driver events in T-cell acute lymphoblastic leukemia

scientific article

Comprehensive miRNA expression profiling in human T-cell acute lymphoblastic leukemia by small RNA-sequencing

scientific article published on 11 August 2017

Copy number defects of G1-cell cycle genes in neuroblastoma are frequent and correlate with high expression of E2F target genes and a poor prognosis

scientific article published on 27 October 2011

Correction to: Epigenetic regulation of neuroblastoma development

scientific article published on 2 February 2018

Correction: Human fetal neuroblast and neuroblastoma transcriptome analysis confirms neuroblast origin and highlights neuroblastoma candidate genes

scientific article

DNA methylation profiling of primary neuroblastoma tumors using methyl-CpG-binding domain sequencing

scientific article

DREAM target reactivation by core transcriptional regulators supports neuroblastoma growth

scientific article published on 03 February 2019

DUP25 remains unconfirmed

scientific article published on 01 December 2004

Delineation of a critical region on chromosome 18 for the del(18)(q12.2q21.1) syndrome

scientific article published on 01 May 2008

Detection of DNA copy number alterations in cancer by array comparative genomic hybridization

scientific article published on September 2007

Dickkopf-3 is regulated by the MYCN-induced miR-17-92 cluster in neuroblastoma

scientific journal article

Disease-causing 7.4 kb cis-regulatory deletion disrupting conserved non-coding sequences and their interaction with the FOXL2 promotor: implications for mutation screening

scientific article

Dual targeting of MDM2 and BCL2 as a therapeutic strategy in neuroblastoma

scientific article published on 4 July 2017

Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia

scientific article published on 15 April 2007

Dynamic Activity of miR-125b and miR-93 during Murine Neural Stem Cell Differentiation In Vitro and in the Subventricular Zone Neurogenic Niche.

scientific article

EVI1 activation in blast crisis CML due to juxtaposition to the rare 17q22 partner region as part of a 4-way variant translocation t(9;22).

scientific article

EVI1 is consistently expressed as principal transcript in common and rare recurrent 3q26 rearrangements

scientific article

EVI1 overexpression in t(3;17) positive myeloid malignancies results from juxtaposition of EVI1 to the MSI2 locus at 17q22.

scientific article

EVI1-mediated down regulation of MIR449A is essential for the survival of EVI1 positive leukaemic cells

scientific article published on 14 May 2011

Effective Alu repeat based RT-Qpcr normalization in cancer cell perturbation experiments

scientific article

Elimination of primer-dimer artifacts and genomic coamplification using a two-step SYBR green I real-time RT-PCR.

scientific article published in April 2002

Emergence of new ALK mutations at relapse of neuroblastoma

scientific article

Epigenetic regulation of neuroblastoma development

scientific article

Epigenetics in T-cell acute lymphoblastic leukemia

scientific article

Evidence for involvement of a tumor suppressor gene on 1p in malignant peripheral nerve sheath tumors

scientific article published in June 2003

Expressed repeat elements improve RT-qPCR normalization across a wide range of zebrafish gene expression studies

scientific article

Expression analyses identify MLL as a prominent target of 11q23 amplification and support an etiologic role for MLL gain of function in myeloid malignancies

scientific article published on 28 August 2003

Expression profiling suggests underexpression of the GABA(A) receptor subunit delta in the fragile X knockout mouse model

scientific article

External oligonucleotide standards enable cross laboratory comparison and exchange of real-time quantitative PCR data

scientific article

Familial pericentric inversion of chromosome 18: behavioral abnormalities in patients heterozygous for either the dup(18p)/del(18q) or dup(18q)/del(18p) recombinant chromosome

scientific article published in January 2005

Focal DNA copy number changes in neuroblastoma target MYCN regulated genes

scientific journal article

From DNA Copy Number Gains and Tumor Dependencies to Novel Therapeutic Targets for High-Risk Neuroblastoma

scientific article published in 2021

Functional analysis of the p53 pathway in neuroblastoma cells using the small-molecule MDM2 antagonist nutlin-3.

scientific article published on April 2011

GAB2 is a novel target of 11q amplification in AML/MDS

scientific article published on 01 September 2006

GATA3 induces human T-cell commitment by restraining Notch activity and repressing NK-cell fate

scientific article published on 6 April 2016

Gene-expression profiling reveals distinct expression patterns for Classic versus Variant Merkel cell phenotypes and new classifier genes to distinguish Merkel cell from small-cell lung carcinoma

scientific article published on April 2004

Genome dynamics of the human embryonic kidney 293 (HEK293) lineage in response to cell biology manipulations

scholarly article by Morgane Boone published in July 2014

Genome dynamics of the human embryonic kidney 293 lineage in response to cell biology manipulations

scientific article

Genome-wide promoter methylation analysis in neuroblastoma identifies prognostic methylation biomarkers

scientific article

Giant axonal neuropathy caused by compound heterozygosity for a maternally inherited microdeletion and a paternal mutation within the GAN gene

article

Glutathione biosynthesis is upregulated at the initiation of MYCN-driven neuroblastoma tumorigenesis.

scientific article published on 2 March 2016

Guidelines for molecular karyotyping in constitutional genetic diagnosis

scientific article

HOXA gene cluster rearrangement in a t(7;9)(p15;q34) in a child with MDS.

scientific article

High ALK receptor tyrosine kinase expression supersedes ALK mutation as a determining factor of an unfavorable phenotype in primary neuroblastoma

scientific article

High resolution tiling-path BAC array deletion mapping suggests commonly involved 3p21-p22 tumor suppressor genes in neuroblastoma and more frequent tumors

scientific article published on February 2007

High-throughput stem-loop RT-qPCR miRNA expression profiling using minute amounts of input RNA.

scientific article published on 21 October 2008

High‐risk clonal evolution in chronic B‐lymphocytic leukemia: single‐center interphase fluorescence in situ hybridization study and review of the literature ⬇️

scientific article published on 07 May 2012

Histone chaperone CHAF1A inhibits differentiation and promotes aggressive neuroblastoma

scientific article published on 12 December 2013

Human fetal neuroblast and neuroblastoma transcriptome analysis confirms neuroblast origin and highlights neuroblastoma candidate genes

scientific article published in January 2006

Hyperdiploidy with 58-66 chromosomes in childhood B-acute lymphoblastic leukemia is highly curable: 58951 CLG-EORTC results.

scientific article published on 15 January 2013

ID2 expression in neuroblastoma does not correlate to MYCN levels and lacks prognostic value

scientific article published in January 2003

Identification of 2 putative critical segments of 17q gain in neuroblastoma through integrative genomics

scientific article published in March 2008

Identification of ALK as a major familial neuroblastoma predisposition gene

scientific article

Identification of BIRC6 as a novel intervention target for neuroblastoma therapy

scientific article

Identification of a novel recurrent 1q42.2-1qter deletion in high risk MYCN single copy 11q deleted neuroblastomas

scientific article

Identification of an unbalanced X-autosome translocation by array CGH in a boy with a syndromic form of chondrodysplasia punctata brachytelephalangic type

scientific article

Identification of cytogenetic subclasses and recurring chromosomal aberrations in AML and MDS with complex karyotypes using m‐FISH ⬇️

scientific article published on January 1, 2002

Identification of two critically deleted regions within chromosome segment 7q35-q36 in EVI1 deregulated myeloid leukemia cell lines

scientific article

Impact of RNA quality on reference gene expression stability

scientific article

Improved detection of chromosomal abnormalities in chronic lymphocytic leukemia by conventional cytogenetics using CpG oligonucleotide and interleukin-2 stimulation: A Belgian multicentric study.

scientific article published in October 2009

In silico discovery of a FOXM1 driven embryonal signaling pathway in therapy resistant neuroblastoma tumors

scientific article published in Scientific Reports

Inhibition of CDK4/6 as a novel therapeutic option for neuroblastoma.

scientific article published on 30 July 2015

Isolation of disseminated neuroblastoma cells from bone marrow aspirates for pretreatment risk assessment by array comparative genomic hybridization.

scientific article

Kallmann syndrome in a patient with congenital spherocytosis and an interstitial 8p11.2 deletion

scientific article published in April 2002

LDHA in Neuroblastoma Is Associated with Poor Outcome and Its Depletion Decreases Neuroblastoma Growth Independent of Aerobic Glycolysis

LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression.

scientific article published on 7 October 2012

LIN28B is over-expressed in specific subtypes of pediatric leukemia and regulates lncRNA H19.

scientific article published on 11 March 2016

LIN28B overexpression defines a novel fetal-like subgroup of juvenile myelomonocytic leukemia.

scientific article published on 28 December 2015

Lack of association between MDM2 promoter SNP309 and clinical outcome in patients with neuroblastoma.

scientific article published on 4 January 2014

Localization of the 17q breakpoint of a constitutional 1;17 translocation in a patient with neuroblastoma within a 25-kb segment located between the ACCN1 and TLK2 genes and near the distal breakpoints of two microdeletions in neurofibromatosis type

scientific article

Long non-coding RNAs in leukemia: biology and clinical impact

scientific article

Long noncoding RNA expression profiling in cancer: Challenges and opportunities

scientific article published on 20 January 2019

Loss-of-function mutations in FGFR1 cause autosomal dominant Kallmann syndrome

scientific article published on 10 March 2003

Loss-of-function mutations in LEMD3 result in osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis

scientific article

Low-cost dedicated mini-arrays for high-throughput analysis of DNA copy-number alterations in neuroblastoma

scientific article published on 13 June 2008

MYCN and HDAC5 transcriptionally repress CD9 to trigger invasion and metastasis in neuroblastoma

scientific article published on 27 August 2016

MYCN-driven regulatory mechanisms controlling LIN28B in neuroblastoma

scientific article published on 26 June 2015

MYCN-targeting miRNAs are predominantly downregulated during MYCN‑driven neuroblastoma tumor formation

scientific article published on March 2015

Mapping biomedical concepts onto the human genome by mining literature on chromosomal aberrations

scientific article published in April 2007

Mate pair sequencing for the detection of chromosomal aberrations in patients with intellectual disability and congenital malformations.

scientific article published on 09 October 2013

Measurable impact of RNA quality on gene expression results from quantitative PCR.

scientific article published on 11 February 2011

Meta-analysis of neuroblastomas reveals a skewed ALK mutation spectrum in tumors with MYCN amplification

scientific article published on 18 August 2010

Meta-mining of copy number profiles of high-risk neuroblastoma tumors

scientific article published on 30 October 2018

Meta-mining of neuroblastoma and neuroblast gene expression profiles reveals candidate therapeutic compounds

scientific article

Methyl-CpG-binding domain sequencing reveals a prognostic methylation signature in neuroblastoma

scientific article published on 6 December 2015

MiR-137 functions as a tumor suppressor in neuroblastoma by downregulating KDM1A.

scientific article published on 7 March 2013

MicroRNA-128-3p is a novel oncomiR targeting PHF6 in T-cell acute lymphoblastic leukemia

scientific article

Molecular basis and clinical significance of genetic aberrations in B-cell precursor acute lymphoblastic leukemia

scientific article published on 19 June 2015

Molecular cytogenetic analysis of complex chromosomal rearrangements in patients with mental retardation and congenital malformations: delineation of 7q21.11 breakpoints

scientific article published in January 2004

Molecular dissection of isolated disease features in mosaic neurofibromatosis type 1.

scientific article

Molecular karyotyping: array CGH quality criteria for constitutional genetic diagnosis.

scientific article published on March 2005

Molecular pathogenesis of multiple gastrointestinal stromal tumors in NF1 patients

scientific article

Multiplex Amplicon Quantification (MAQ), a fast and efficient method for the simultaneous detection of copy number alterations in neuroblastoma

scientific article

Mutational dynamics between primary and relapse neuroblastomas.

scientific article

N-cadherin in neuroblastoma disease: expression and clinical significance

scientific article

Neuroblastoma cells with overexpressed MYCN retain their capacity to undergo neuronal differentiation

scientific article published on April 2004

Neuroblastoma epigenetics: from candidate gene approaches to genome-wide screenings

scientific article published on August 2011

Neuroblastoma genetics and phenotype: a tale of heterogeneity

scientific article published on 04 August 2011

Neuroblastoma: A Tough Nut to Crack

scientific article published on January 2016

No Evidence for Correlation of DDX1 Gene Amplification With Improved Survival Probability in Patients With MYCN-Amplified Neuroblastomas

article

No evidence for involvement of SDHD in neuroblastoma pathogenesis

scientific article

Novel biological insights in T-cell acute lymphoblastic leukemia

scientific article published on 26 June 2015

Novel cryptic chromosomal rearrangements in childhood acute lymphoblastic leukemia detected by multiple color fluorescent in situ hybridization

scientific article

Osteopoikilosis, short stature and mental retardation as key features of a new microdeletion syndrome on 12q14

scientific article published on 12 January 2007

Overall genomic pattern is a predictor of outcome in neuroblastoma

scientific article

PAX5/IGH rearrangement is a recurrent finding in a subset of aggressive B-NHL with complex chromosomal rearrangements

scientific article

PHF6 mutations in T-cell acute lymphoblastic leukemia

scientific article (publication date: 14 March 2010)

PRDM16 (1p36) translocations define a distinct entity of myeloid malignancies with poor prognosis but may also occur in lymphoid malignancies

scientific article published on 3 November 2011

PRL3 enhances T-cell acute lymphoblastic leukemia growth through suppressing T-cell signaling pathways and apoptosis

scientific article published on 30 June 2020

Pharmacologic activation of wild-type p53 by nutlin therapy in childhood cancer

scientific article

Pharmacological activation of the p53 pathway by nutlin-3 exerts anti-tumoral effects in medulloblastomas

scientific article

Positional and functional mapping of a neuroblastoma differentiation gene on chromosome 11

scientific article

Positional gene enrichment analysis of gene sets for high-resolution identification of overrepresented chromosomal regions

scientific article published on 16 March 2008

Predicting outcomes for children with neuroblastoma using a multigene-expression signature: a retrospective SIOPEN/COG/GPOH study

scientific article

Predicting outcomes for children with neuroblastoma.

scientific article published on July 2010

Prognostic impact of gene expression-based classification for neuroblastoma.

scientific article published on 21 June 2010

Promoter-associated proteins of EPAS1 identified by enChIP-MS - A putative role of HDX as a negative regulator

scientific article published on 22 March 2018

Proneural and proneuroendocrine transcription factor expression in cutaneous mechanoreceptor (Merkel) cells and Merkel cell carcinoma

scientific article

Publisher Correction: In silico discovery of a FOXM1 driven embryonal signaling pathway in therapy resistant neuroblastoma tumors.

scientific article published on 4 June 2019

Purification of high-quality RNA from a small number of fluorescence activated cell sorted zebrafish cells for RNA sequencing purposes

Quantification of MYCN, DDX1, and NAG gene copy number in neuroblastoma using a real-time quantitative PCR assay

scientific article published in February 2002

Quantitative real time polymerase chain reaction for measurement of human interleukin-5 receptor alpha spliced isoforms mRNA

scientific article

RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer

scientific article

RNA pre-amplification enables large-scale RT-qPCR gene-expression studies on limiting sample amounts

scientific article

RTPrimerDB: the portal for real-time PCR primers and probes

scientific article published on 23 October 2008

RTPrimerDB: the real-time PCR primer and probe database

scientific article published on January 2003

RTPrimerDB: the real-time PCR primer and probe database, major update 2006.

scientific article

Rapid detection of VHL exon deletions using real-time quantitative PCR.

scientific article published in January 2005

Real-time quantitative PCR as an alternative to Southern blot or fluorescence in situ hybridization for detection of gene copy number changes

scientific article

Real-time quantitative allele discrimination assay using 3' locked nucleic acid primers for detection of low-percentage mosaic mutations

scientific article published on 14 August 2006

Recurrent rearrangements of chromosome 1q21.1 and variable pediatric phenotypes

scientific article

Refinement of 1p36 alterations not involving PRDM16 in myeloid and lymphoid malignancies

scientific article

Refinement of the critical 2p25.3 deletion region: the role of MYT1L in intellectual disability and obesity.

scientific article published on 18 September 2014

Regulation of peroxisomal genes by DHEA and vitamin D.

scientific article

Report of a female patient with mental retardation and tall stature due to a chromosomal rearrangement disrupting the OPHN1 gene on Xq12

scientific article published on 06 August 2007

Revised risk estimation and treatment stratification of low- and intermediate-risk neuroblastoma patients by integrating clinical and molecular prognostic markers

scientific article published on 17 September 2014

Shallow Whole Genome Sequencing on Circulating Cell-Free DNA Allows Reliable Noninvasive Copy-Number Profiling in Neuroblastoma Patients

scientific article published on 14 July 2017

Signaling of ERBB receptor tyrosine kinases promotes neuroblastoma growth in vitro and in vivo

scientific article

Small-molecule MDM2 antagonists as a new therapy concept for neuroblastoma

scientific article published on October 2006

Smoothing waves in array CGH tumor profiles

scientific article published on 10 March 2009

Somatic loss of wild type NF1 allele in neurofibromas: Comparison of NF1 microdeletion and non-microdeletion patients

scientific article

Subtelomeric imbalances in phenotypically normal individuals

scientific article published in October 2007

Synthetic lethality between Rb, p53 and Dicer or miR-17-92 in retinal progenitors suppresses retinoblastoma formation

scientific article published on 5 August 2012

T-ALL and thymocytes: a message of noncoding RNAs

scientific article published on 7 March 2017

TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets

scientific article published in Nature Communications

Targeted expression of mutated ALK induces neuroblastoma in transgenic mice.

scientific article published in July 2012

Targeting tachykinin receptors in neuroblastoma

scientific article

The 12q14 microdeletion syndrome: additional patients and further evidence that HMGA2 is an important genetic determinant for human height

scientific article published on 17 March 2009

The ETS transcription factor ETV5 is a target of activated ALK in neuroblastoma contributing to increased tumour aggressiveness

scientific article published on 14 January 2020

The H3K27me3 demethylase UTX in normal development and disease

scientific article

The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia

scientific article

The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia

scientific article

The TLX1 oncogene drives aneuploidy in T cell transformation

scientific article

The emerging molecular pathogenesis of neuroblastoma: implications for improved risk assessment and targeted therapy

scientific article published on 27 July 2009

The epigenetic landscape of T-cell acute lymphoblastic leukemia

scientific article published on 28 April 2014

The miR-17-92 microRNA cluster regulates multiple components of the TGF-β pathway in neuroblastoma

scientific article published on December 2010

The microRNA body map: dissecting microRNA function through integrative genomics

scientific article published on 10 August 2011

The mutational landscape of MYCN, Lin28b and ALKF1174L driven murine neuroblastoma mimics human disease

scientific article published on 22 December 2017

The quassinoid derivative NBT-272 targets both the AKT and ERK signaling pathways in embryonal tumors

scientific article published on October 2010

The von Hippel-Lindau tumor suppressor gene expression level has prognostic value in neuroblastoma

scientific article

Therapeutic targeting of the MYC signal by inhibition of histone chaperone FACT in neuroblastoma.

scientific article

Translating expression profiling into a clinically feasible test to predict neuroblastoma outcome

scientific article published in March 2007

Translocation-excision-deletion-amplification mechanism leading to nonsyntenic coamplification of MYC and ATBF1.

scientific article published on February 2006

Unequivocal delineation of clinicogenetic subgroups and development of a new model for improved outcome prediction in neuroblastoma

scientific article

Unique long non-coding RNA expression signature in ETV6/RUNX1-driven B-cell precursor acute lymphoblastic leukemia

scientific article published on 16 September 2016

Unusual 8p inverted duplication deletion with telomere capture from 8q.

scientific article

Upregulation of MAPK Negative Feedback Regulators and RET in Mutant ALK Neuroblastoma: Implications for Targeted Treatment

scientific article

ViVar: a comprehensive platform for the analysis and visualization of structural genomic variation

scientific article

Widespread dysregulation of MiRNAs by MYCN amplification and chromosomal imbalances in neuroblastoma: association of miRNA expression with survival

scientific article

ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling.

scientific article

arrayCGHbase: an analysis platform for comparative genomic hybridization microarrays

scientific article

methBLAST and methPrimerDB: web-tools for PCR based methylation analysis

scientific article published on 9 November 2006

methGraph: a genome visualization tool for PCR-based methylation assays.

scientific article

miR-135a Inhibits Cancer Stem Cell-Driven Medulloblastoma Development by Directly Repressing Arhgef6 Expression

scientific article published in May 2015

miR-542-3p exerts tumor suppressive functions in neuroblastoma by downregulating Survivin

scientific article

miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis

scientific article

miRNA expression profiling enables risk stratification in archived and fresh neuroblastoma tumor samples

scientific article

qBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data

scientific article (publication date: 2007)

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