List of works - Pier Luigi Tazzari

A combination of temsirolimus, an allosteric mTOR inhibitor, with clofarabine as a new therapeutic option for patients with acute myeloid leukemia

scientific article published on December 2012

A non-invasive strategy for haemoglobin screening of blood donors

scientific article

A novel stem cell tag-less sorting method

scientific article published on 01 December 2009

A simple method for identifying bone marrow mesenchymal stromal cells with a high immunosuppressive potential

scientific article published on 20 December 2010

ATG-saporin-S6 immunotoxin: a new potent and selective drug to eliminate activated lymphocytes and lymphoma cells

scientific article published on 18 September 2009

Activity of the novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 against T-cell acute lymphoblastic leukemia.

scientific article published on 28 September 2010

Application of flow cytometry to molecular medicine: detection of tumor necrosis factor-related apoptosis-inducing ligand receptors in acute myeloid leukaemia blasts

scientific article published on December 2005

CTLA-4 is constitutively expressed on tumor cells and can trigger apoptosis upon ligand interaction

scientific article

CTLA-4 is not restricted to the lymphoid cell lineage and can function as a target molecule for apoptosis induction of leukemic cells.

scientific article published on 15 August 2002

Caspase-dependent cleavage of 170-kDa P-glycoprotein during apoptosis of human T-lymphoblastoid CEM cells

scientific article published on June 2006

Change in conformation with reduction of alpha-helix content causes loss of neutrophil binding activity in fully cytotoxic Shiga toxin 1.

scientific article

Clinical relevance of shiga toxin concentrations in the blood of patients with hemolytic uremic syndrome

scientific article

Deguelin, A PI3K/AKT inhibitor, enhances chemosensitivity of leukaemia cells with an active PI3K/AKT pathway

scientific article

Dendritic cells of immune thrombocytopenic purpura (ITP) show increased capacity to present apoptotic platelets to T lymphocytes

scientific article

Dual inhibition of class IA phosphatidylinositol 3-kinase and mammalian target of rapamycin as a new therapeutic option for T-cell acute lymphoblastic leukemia

scientific article published on 07 April 2009

Endothelial damage induced by Shiga toxins delivered by neutrophils during transmigration

scientific article

Experience in the evaluation of foeto-maternal haemorrhage by flow cytometry ⬇️

scientific article published on October 10, 2012

Flow cytometric detection of total and serine 473 phosphorylated Akt.

scientific article published on January 2002

Flow cytometry detection of Shiga toxins in the blood from children with hemolytic uremic syndrome

scientific article

Flow cytometry detection of serotonin content and release in resting and activated platelets

scientific article

Gene expression profiling of normal and malignant CD34-derived megakaryocytic cells

article

Gravitational field-flow fractionation of human hemopoietic stem cells

article

HIV-1 and recombinant gp120 affect the survival and differentiation of human vessel wall-derived mesenchymal stem cells

scientific article

Harnessing the PI3K/Akt/mTOR pathway in T-cell acute lymphoblastic leukemia: eliminating activity by targeting at different levels

scientific article

Human cadaver multipotent stromal/stem cells isolated from arteries stored in liquid nitrogen for 5 years

scientific article published on 15 January 2014

Human lymphocyte sorting by gravitational field-flow fractionation

scientific article

Identification of TLR4 as the receptor that recognizes Shiga toxins in human neutrophils

scientific article

Identification of a functional nuclear export sequence in diacylglycerol kinase-zeta.

scientific article published on 29 January 2010

Increased mortality rate and not impaired ribosomal biogenesis is responsible for proliferative defect in dyskeratosis congenita cell lines.

scientific article published on January 2002

Interactions between Shiga toxins and human polymorphonuclear leukocytes

scientific article

Isolation of stem cell populations with trophic and immunoregulatory functions from human intestinal tissues: potential for cell therapy in inflammatory bowel disease

scientific article

Multidistrict human mesenchymal vascular cells: pluripotency and stemness characteristics

scientific article

Neutrophil gelatinase-associated lipocalin increases HLA-G(+)/FoxP3(+) T-regulatory cell population in an in vitro model of PBMC.

scientific article

New laboratory test in flow cytometry for the combined analysis of serologic and cellular parameters in the diagnosis of heparin-induced thrombocytopenia

scientific article

Novel 2'-substituted, 3'-deoxy-phosphatidyl-myo-inositol analogues reduce drug resistance in human leukaemia cell lines with an activated phosphoinositide 3-kinase/Akt pathway

scientific article

Nuclear diacylglycerol kinase-zeta is a negative regulator of cell cycle progression in C2C12 mouse myoblasts

scientific article published on 8 May 2007

Phosphoinositide 3-kinase/Akt inhibition increases arsenic trioxide-induced apoptosis of acute promyelocytic and T-cell leukaemias

scientific article published on September 2005

Phosphoinositide 3-kinase/Akt involvement in arsenic trioxide resistance of human leukemia cells

scientific article

Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor (2S)-1-(1H-Indol-3-yl)-3-[5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl]oxypropan2-amine (A443654) in T-cell acute lymphoblastic leukemia

scientific article published on 24 June 2008

Quantitatively different red cell/nucleated cell chimerism in patients with long-term, persistent hematopoietic mixed chimerism after bone marrow transplantation for thalassemia major or sickle cell disease ⬇️

scientific article published on October 7, 2010

Restored in vivo-like membrane lipidomics positively influence in vitro features of cultured mesenchymal stromal/stem cells derived from human placenta

scientific article published on 07 February 2017

Shiga toxin 1 and ricin A chain bind to human polymorphonuclear leucocytes through a common receptor ⬇️

scientific article published on November 15, 2010

Shiga toxin 1, as DNA repair inhibitor, synergistically potentiates the activity of the anticancer drug, mafosfamide, on raji cells

scientific article published on 21 February 2013

Shiga toxins present in the gut and in the polymorphonuclear leukocytes circulating in the blood of children with hemolytic-uremic syndrome

scientific article

Synergistic proapoptotic activity of recombinant TRAIL plus the Akt inhibitor Perifosine in acute myelogenous leukemia cells

scientific article

Targeting signaling pathways in T-cell acute lymphoblastic leukemia initiating cells

scientific article published on 30 April 2014

Term Amniotic membrane is a high throughput source for multipotent Mesenchymal Stem Cells with the ability to differentiate into endothelial cells in vitro

scientific article

The Antibiotic Polymyxin B Impairs the Interactions between Shiga Toxins and Human Neutrophils.

scientific article

The phosphoinositide 3-kinase/AKT1 pathway involvement in drug and all-trans-retinoic acid resistance of leukemia cells

scientific article

Thoracic aortas from multiorgan donors are suitable for obtaining resident angiogenic mesenchymal stromal cells

Transfusion-related Listeria monocytogenes infection in a patient with acute myeloid leukaemia

scientific article

List of works by Pier Luigi Tazzari

A combination of temsirolimus, an allosteric mTOR inhibitor, with clofarabine as a new therapeutic option for patients with acute myeloid leukemia

A non-invasive strategy for haemoglobin screening of blood donors

A novel stem cell tag-less sorting method

A simple method for identifying bone marrow mesenchymal stromal cells with a high immunosuppressive potential

ATG-saporin-S6 immunotoxin: a new potent and selective drug to eliminate activated lymphocytes and lymphoma cells

Activity of the novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 against T-cell acute lymphoblastic leukemia.

Application of flow cytometry to molecular medicine: detection of tumor necrosis factor-related apoptosis-inducing ligand receptors in acute myeloid leukaemia blasts

CTLA-4 is constitutively expressed on tumor cells and can trigger apoptosis upon ligand interaction

CTLA-4 is not restricted to the lymphoid cell lineage and can function as a target molecule for apoptosis induction of leukemic cells.

Caspase-dependent cleavage of 170-kDa P-glycoprotein during apoptosis of human T-lymphoblastoid CEM cells

Change in conformation with reduction of alpha-helix content causes loss of neutrophil binding activity in fully cytotoxic Shiga toxin 1.

Clinical relevance of shiga toxin concentrations in the blood of patients with hemolytic uremic syndrome

Deguelin, A PI3K/AKT inhibitor, enhances chemosensitivity of leukaemia cells with an active PI3K/AKT pathway

Dendritic cells of immune thrombocytopenic purpura (ITP) show increased capacity to present apoptotic platelets to T lymphocytes

Dual inhibition of class IA phosphatidylinositol 3-kinase and mammalian target of rapamycin as a new therapeutic option for T-cell acute lymphoblastic leukemia

Endothelial damage induced by Shiga toxins delivered by neutrophils during transmigration

Experience in the evaluation of foeto-maternal haemorrhage by flow cytometry ⬇️

Flow cytometric detection of total and serine 473 phosphorylated Akt.

Flow cytometry detection of Shiga toxins in the blood from children with hemolytic uremic syndrome

Flow cytometry detection of serotonin content and release in resting and activated platelets

Gene expression profiling of normal and malignant CD34-derived megakaryocytic cells

Gravitational field-flow fractionation of human hemopoietic stem cells

HIV-1 and recombinant gp120 affect the survival and differentiation of human vessel wall-derived mesenchymal stem cells

Harnessing the PI3K/Akt/mTOR pathway in T-cell acute lymphoblastic leukemia: eliminating activity by targeting at different levels

Human cadaver multipotent stromal/stem cells isolated from arteries stored in liquid nitrogen for 5 years

Human lymphocyte sorting by gravitational field-flow fractionation

Identification of TLR4 as the receptor that recognizes Shiga toxins in human neutrophils

Identification of a functional nuclear export sequence in diacylglycerol kinase-zeta.

Increased mortality rate and not impaired ribosomal biogenesis is responsible for proliferative defect in dyskeratosis congenita cell lines.

Interactions between Shiga toxins and human polymorphonuclear leukocytes

Isolation of stem cell populations with trophic and immunoregulatory functions from human intestinal tissues: potential for cell therapy in inflammatory bowel disease

Multidistrict human mesenchymal vascular cells: pluripotency and stemness characteristics

Neutrophil gelatinase-associated lipocalin increases HLA-G(+)/FoxP3(+) T-regulatory cell population in an in vitro model of PBMC.

New laboratory test in flow cytometry for the combined analysis of serologic and cellular parameters in the diagnosis of heparin-induced thrombocytopenia

Novel 2'-substituted, 3'-deoxy-phosphatidyl-myo-inositol analogues reduce drug resistance in human leukaemia cell lines with an activated phosphoinositide 3-kinase/Akt pathway

Nuclear diacylglycerol kinase-zeta is a negative regulator of cell cycle progression in C2C12 mouse myoblasts

Phosphoinositide 3-kinase/Akt inhibition increases arsenic trioxide-induced apoptosis of acute promyelocytic and T-cell leukaemias

Phosphoinositide 3-kinase/Akt involvement in arsenic trioxide resistance of human leukemia cells

Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor (2S)-1-(1H-Indol-3-yl)-3-[5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl]oxypropan2-amine (A443654) in T-cell acute lymphoblastic leukemia

Quantitatively different red cell/nucleated cell chimerism in patients with long-term, persistent hematopoietic mixed chimerism after bone marrow transplantation for thalassemia major or sickle cell disease ⬇️

Restored in vivo-like membrane lipidomics positively influence in vitro features of cultured mesenchymal stromal/stem cells derived from human placenta

Shiga toxin 1 and ricin A chain bind to human polymorphonuclear leucocytes through a common receptor ⬇️

Shiga toxin 1, as DNA repair inhibitor, synergistically potentiates the activity of the anticancer drug, mafosfamide, on raji cells

Shiga toxins present in the gut and in the polymorphonuclear leukocytes circulating in the blood of children with hemolytic-uremic syndrome

Synergistic proapoptotic activity of recombinant TRAIL plus the Akt inhibitor Perifosine in acute myelogenous leukemia cells

Targeting signaling pathways in T-cell acute lymphoblastic leukemia initiating cells

Term Amniotic membrane is a high throughput source for multipotent Mesenchymal Stem Cells with the ability to differentiate into endothelial cells in vitro

The Antibiotic Polymyxin B Impairs the Interactions between Shiga Toxins and Human Neutrophils.

The phosphoinositide 3-kinase/AKT1 pathway involvement in drug and all-trans-retinoic acid resistance of leukemia cells

Thoracic aortas from multiorgan donors are suitable for obtaining resident angiogenic mesenchymal stromal cells

Transfusion-related Listeria monocytogenes infection in a patient with acute myeloid leukaemia