List of works - Girolamo Calò

A diastereoselective synthesis of Cebranopadol, a novel analgesic showing NOP/mu mixed agonism

scientific article

A novel and facile synthesis of tetra branched derivatives of nociceptin/orphanin FQ.

scientific article published on 13 May 2014

Antidepressant- and anxiolytic-like effects of nociceptin/orphanin FQ receptor ligands.

scientific article

Central injections of nocistatin or its C-terminal hexapeptide exert anxiogenic-like effect on behaviour of mice in the plus-maze test

scientific article

Correction for "Synthesis of Mixed Opioid Affinity Cyclic Endomorphin-2 Analogues with Fluorinated Phenylalanines".

scientific article published on 9 May 2016

Cyclic mu-opioid receptor ligands containing multiple N-methylated amino acid residues

scientific article

Cyclopeptide Dmt-[D-Lys-p-CF3-Phe-Phe-Asp]NH2, a novel G protein-biased agonist of the mu opioid receptor

scientific article published on 28 November 2017

Effect of neuropeptide S receptor antagonists and partial agonists on palatable food consumption in the rat

scientific journal article

Exploring pharmacological activities and signaling of morphinans substituted in position 6 as potent agonists interacting with the μ opioid receptor

scientific article

In vitro and in vivo activity of opioid cyclopeptide with mu/delta agonist profile biased toward β-arrestin.

scientific article published on 20 April 2018

In vitro and in vivo characterisation of the bifunctional MOP/DOP ligand UFP-505.

scientific article published on 10 March 2018

In vitro and in vivo pharmacological characterization of a neuropeptide S tetrabranched derivative.

scientific article

In vitro and in vivo pharmacological characterization of the novel NK₁ receptor selective antagonist Netupitant

scientific article

In vitro and in vivo studies on UFP-112, a novel potent and long lasting agonist selective for the nociceptin/orphanin FQ receptor

scientific article

In vitro functional characterization of novel nociceptin/orphanin FQ receptor agonists in recombinant and native preparations.

scientific article published on 22 October 2016

Neuropeptide S: a novel regulator of pain-related amygdala plasticity and behaviors

scientific article published on 24 July 2013

Nociceptin receptor antagonists display antidepressant-like properties in the mouse forced swimming test

scientific article (publication date: February 2002)

Nociceptin/Orphanin FQ Receptor Structure, Signaling, Ligands, Functions, and Interactions with Opioid Systems

scientific article published on 8 March 2016

Pharmacological characterization of cebranopadol a novel analgesic acting as mixed nociceptin/orphanin FQ and opioid receptor agonist

scientific article published on 02 August 2016

Pharmacological characterization of endomorphin-2-based cyclic pentapeptides with methylated phenylalanine residues.

scientific article published on 13 March 2014

Pharmacological characterization of tachykinin tetrabranched derivatives

scientific article

Pharmacological characterization of the novel nociceptin/orphanin FQ receptor ligand, ZP120: in vitro and in vivo studies in mice

scientific article

Pharmacological investigations of N-substituent variation in morphine and oxymorphone: opioid receptor binding, signaling and antinociceptive activity

scientific article

Pharmacological profile of nociceptin/orphanin FQ receptors

scientific article

Pharmacological profiles of presynaptic nociceptin/orphanin FQ receptors modulating 5-hydroxytryptamine and noradrenaline release in the rat neocortex

scientific article

Pharmacological studies on the NOP and opioid receptor agonist PWT2-[Dmt1]N/OFQ(1-13).

scientific article

Redoubling the ring size of an endomorphin-2 analog transforms a centrally acting mu-opioid receptor agonist into a pure peripheral analgesic

scientific article

Ring size in cyclic endomorphin-2 analogs modulates receptor binding affinity and selectivity.

scientific article published in June 2015

Selective breeding for high anxiety introduces a synonymous SNP that increases neuropeptide S receptor activity.

scientific article published on March 2015

Structural bacterial molecules as potential candidates for an evolution of the classical concept of probiotics

scientific article

Structure activity studies of nociceptin/orphanin FQ(1-13)-NH2 derivatives modified in position 5.

scientific article

Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic

scientific article

Structure-activity study at positions 3 and 4 of human neuropeptide S.

scientific article

Synthesis and Pharmacological Evaluation of Hybrids Targeting Opioid and Neurokinin Receptors

scientific article published on 05 December 2019

Synthesis and activity of opioid peptidomimetics with β2- and β3-amino acids

scientific article published on 3 August 2017

Synthesis and biological activity of human neuropeptide S analogues modified in position 2.

scientific article

Synthesis and separation of the enantiomers of the neuropeptide S receptor antagonist (9R/S)-3-oxo-1,1-diphenyl-tetrahydro-oxazolo[3,4-a]pyrazine-7-carboxylic acid 4-fluoro-benzylamide (SHA 68).

scientific article

Synthesis of mixed MOR/KOR efficacy cyclic opioid peptide analogs with antinociceptive activity after systemic administration

scientific article published on 12 December 2015

Synthesis of mixed opioid affinity cyclic endomorphin-2 analogues with fluorinated phenylalanines

scientific article published on 3 April 2015

Synthesis, biological evaluation and structural analysis of novel peripherally active morphiceptin analogs.

scientific article published on 26 February 2016

The effects of neuropeptide S on general anesthesia in rats

scientific journal article

The nociceptin/orphanin FQ receptor antagonist UFP-101 reduces microvascular inflammation to lipopolysaccharide in vivo

scientific article

The peptidic urotensin-II receptor ligand GSK248451 possesses less intrinsic activity than the low-efficacy partial agonists SB-710411 and urantide in native mammalian tissues and recombinant cell systems

scientific article

UFP-101, a peptide antagonist selective for the nociceptin/orphanin FQ receptor.

scientific article

[Nphe1,Arg14,Lys15]nociceptin-NH2, a novel potent and selective antagonist of the nociceptin/orphanin FQ receptor.

scientific article

List of works by Girolamo Calò

A diastereoselective synthesis of Cebranopadol, a novel analgesic showing NOP/mu mixed agonism

A novel and facile synthesis of tetra branched derivatives of nociceptin/orphanin FQ.

Antidepressant- and anxiolytic-like effects of nociceptin/orphanin FQ receptor ligands.

Central injections of nocistatin or its C-terminal hexapeptide exert anxiogenic-like effect on behaviour of mice in the plus-maze test

Correction for "Synthesis of Mixed Opioid Affinity Cyclic Endomorphin-2 Analogues with Fluorinated Phenylalanines".

Cyclic mu-opioid receptor ligands containing multiple N-methylated amino acid residues

Cyclopeptide Dmt-[D-Lys-p-CF3-Phe-Phe-Asp]NH2, a novel G protein-biased agonist of the mu opioid receptor

Effect of neuropeptide S receptor antagonists and partial agonists on palatable food consumption in the rat

Exploring pharmacological activities and signaling of morphinans substituted in position 6 as potent agonists interacting with the μ opioid receptor

In vitro and in vivo activity of opioid cyclopeptide with mu/delta agonist profile biased toward β-arrestin.

In vitro and in vivo characterisation of the bifunctional MOP/DOP ligand UFP-505.

In vitro and in vivo pharmacological characterization of a neuropeptide S tetrabranched derivative.

In vitro and in vivo pharmacological characterization of the novel NK₁ receptor selective antagonist Netupitant

In vitro and in vivo studies on UFP-112, a novel potent and long lasting agonist selective for the nociceptin/orphanin FQ receptor

In vitro functional characterization of novel nociceptin/orphanin FQ receptor agonists in recombinant and native preparations.

Neuropeptide S: a novel regulator of pain-related amygdala plasticity and behaviors

Nociceptin receptor antagonists display antidepressant-like properties in the mouse forced swimming test

Nociceptin/Orphanin FQ Receptor Structure, Signaling, Ligands, Functions, and Interactions with Opioid Systems

Pharmacological characterization of cebranopadol a novel analgesic acting as mixed nociceptin/orphanin FQ and opioid receptor agonist

Pharmacological characterization of endomorphin-2-based cyclic pentapeptides with methylated phenylalanine residues.

Pharmacological characterization of tachykinin tetrabranched derivatives

Pharmacological characterization of the novel nociceptin/orphanin FQ receptor ligand, ZP120: in vitro and in vivo studies in mice

Pharmacological investigations of N-substituent variation in morphine and oxymorphone: opioid receptor binding, signaling and antinociceptive activity

Pharmacological profile of nociceptin/orphanin FQ receptors

Pharmacological profiles of presynaptic nociceptin/orphanin FQ receptors modulating 5-hydroxytryptamine and noradrenaline release in the rat neocortex

Pharmacological studies on the NOP and opioid receptor agonist PWT2-[Dmt1]N/OFQ(1-13).

Redoubling the ring size of an endomorphin-2 analog transforms a centrally acting mu-opioid receptor agonist into a pure peripheral analgesic

Ring size in cyclic endomorphin-2 analogs modulates receptor binding affinity and selectivity.

Selective breeding for high anxiety introduces a synonymous SNP that increases neuropeptide S receptor activity.

Structural bacterial molecules as potential candidates for an evolution of the classical concept of probiotics

Structure activity studies of nociceptin/orphanin FQ(1-13)-NH2 derivatives modified in position 5.

Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic

Structure-activity study at positions 3 and 4 of human neuropeptide S.

Synthesis and Pharmacological Evaluation of Hybrids Targeting Opioid and Neurokinin Receptors

Synthesis and activity of opioid peptidomimetics with β2- and β3-amino acids

Synthesis and biological activity of human neuropeptide S analogues modified in position 2.

Synthesis and separation of the enantiomers of the neuropeptide S receptor antagonist (9R/S)-3-oxo-1,1-diphenyl-tetrahydro-oxazolo[3,4-a]pyrazine-7-carboxylic acid 4-fluoro-benzylamide (SHA 68).

Synthesis of mixed MOR/KOR efficacy cyclic opioid peptide analogs with antinociceptive activity after systemic administration

Synthesis of mixed opioid affinity cyclic endomorphin-2 analogues with fluorinated phenylalanines

Synthesis, biological evaluation and structural analysis of novel peripherally active morphiceptin analogs.

The effects of neuropeptide S on general anesthesia in rats

The nociceptin/orphanin FQ receptor antagonist UFP-101 reduces microvascular inflammation to lipopolysaccharide in vivo

The peptidic urotensin-II receptor ligand GSK248451 possesses less intrinsic activity than the low-efficacy partial agonists SB-710411 and urantide in native mammalian tissues and recombinant cell systems

UFP-101, a peptide antagonist selective for the nociceptin/orphanin FQ receptor.

[Nphe1,Arg14,Lys15]nociceptin-NH2, a novel potent and selective antagonist of the nociceptin/orphanin FQ receptor.