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Authors whose works are in public domain in at least one jurisdiction

List of works by Roger E McLendon

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An integrated genomic analysis of human glioblastoma multiforme

scientific article
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

scientific article (publication date: 7 December 2006)
IDH1 and IDH2 mutations in gliomas

scientific article
TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

scientific article published on 25 March 2013
Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells

scientific article published on June 2009
Altered telomeres in tumors with ATRX and DAXX mutations

scientific article
The genetic landscape of the childhood cancer medulloblastoma

scientific article
Immunologic Escape After Prolonged Progression-Free Survival With Epidermal Growth Factor Receptor Variant III Peptide Vaccination in Patients With Newly Diagnosed Glioblastoma

scientific article published on October 4, 2010
Subgroup-specific structural variation across 1,000 medulloblastoma genomes

scientific article
The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype

scientific article
Phase II trial of gefitinib in recurrent glioblastoma

scientific article published on 24 November 2003
Glioblastoma stem cells generate vascular pericytes to support vessel function and tumor growth.

scientific article published on March 2013
Integrin alpha 6 regulates glioblastoma stem cells

scientific article
Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas

scientific article
Mutations in CIC and FUBP1 contribute to human oligodendroglioma

scientific article (publication date: 9 September 2011)
Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth

scientific article published on January 12, 2015
The integrated landscape of driver genomic alterations in glioblastoma

scientific article published on 05 August 2013
Sensitive detection of human cytomegalovirus in tumors and peripheral blood of patients diagnosed with glioblastoma

scientific article
Targeting cancer stem cells through L1CAM suppresses glioma growth

scientific article published on August 2008
Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

article
c-Myc is required for maintenance of glioma cancer stem cells

scientific article
Greater chemotherapy-induced lymphopenia enhances tumor-specific immune responses that eliminate EGFRvIII-expressing tumor cells in patients with glioblastoma

scientific article published on December 10, 2010
Tetanus toxoid and CCL3 improve dendritic cell vaccines in mice and glioblastoma patients

scientific article published on March 11, 2015
Identification of CD15 as a marker for tumor-propagating cells in a mouse model of medulloblastoma

scientific article published on February 2009
Targeting interleukin 6 signaling suppresses glioma stem cell survival and tumor growth

scientific article
Mutations of PIK3CA in Anaplastic Oligodendrogliomas, High-Grade Astrocytomas, and Medulloblastomas

Glioma stem cell proliferation and tumor growth are promoted by nitric oxide synthase-2

scientific article
An animal model of MYC-driven medulloblastoma

scientific article published on February 2012
The whole-genome landscape of medulloblastoma subtypes

scientific article published in July 2017
Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis

scientific article published on 17 October 2013
Tumor angiogenic and hypoxic profiles predict radiographic response and survival in malignant astrocytoma patients treated with bevacizumab and irinotecan

scientific article published on January 2008
Gene expression profiling and genetic markers in glioblastoma survival

scientific article published in May 2005
Phase II study of imatinib mesylate plus hydroxyurea in adults with recurrent glioblastoma multiforme

scientific article
Nonreceptor Tyrosine Kinase BMX Maintains Self-Renewal and Tumorigenic Potential of Glioblastoma Stem Cells by Activating STAT3

scientific article published on April 12, 2011
Brain cancer stem cells display preferential sensitivity to Akt inhibition

scientific article published on 18 September 2008
Phase 2 trial of erlotinib plus sirolimus in adults with recurrent glioblastoma

scientific article
Clinical experience with alpha-particle emitting 211At: treatment of recurrent brain tumor patients with 211At-labeled chimeric antitenascin monoclonal antibody 81C6

scientific article
Phase II trial of temozolomide plus o6-benzylguanine in adults with recurrent, temozolomide-resistant malignant glioma

scientific article
Progress report of a Phase I study of the intracerebral microinfusion of a recombinant chimeric protein composed of transforming growth factor (TGF)-alpha and a mutated form of the Pseudomonas exotoxin termed PE-38 (TP-38) for the treatment of malig

scientific article published in October 2003
Intracerebral infusion of an EGFR-targeted toxin in recurrent malignant brain tumors

scientific article published on 10 April 2008
Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas

scientific article
Phase 1 trial of gefitinib plus sirolimus in adults with recurrent malignant glioma

scientific article
Phase II trial of bevacizumab and erlotinib in patients with recurrent malignant glioma

scientific article
A Three-Dimensional Organoid Culture System Derived from Human Glioblastomas Recapitulates the Hypoxic Gradients and Cancer Stem Cell Heterogeneity of Tumors Found In Vivo

scientific article published on 19 February 2016
Phase I trial of temozolomide plus O6-benzylguanine for patients with recurrent or progressive malignant glioma

scientific article
Phase II trial of temozolomide in patients with progressive low-grade glioma

scientific article
Recurrent Glioblastoma Treated with Recombinant Poliovirus

scientific article
Phase II trial of murine (131)I-labeled antitenascin monoclonal antibody 81C6 administered into surgically created resection cavities of patients with newly diagnosed malignant gliomas

scientific article published in March 2002
Combination therapy of inhibitors of epidermal growth factor receptor/vascular endothelial growth factor receptor 2 (AEE788) and the mammalian target of rapamycin (RAD001) offers improved glioblastoma tumor growth inhibition.

scientific article
Phase II study of carboplatin, irinotecan, and bevacizumab for bevacizumab naïve, recurrent glioblastoma

scientific article

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