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List of works by John K Buolamwini

3D-QSAR and docking studies on 4-anilinoquinazoline and 4-anilinoquinoline epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors

scientific article

6-Benzylthioinosine analogues: promising anti-toxoplasmic agents as inhibitors of the mammalian nucleoside transporter ENT1 (es).

scientific article published on 23 November 2005

A Small-Molecule Inhibitor of MDMX Activates p53 and Induces Apoptosis ⬇️

scientific article published on November 12, 2010

A quantitative LC-MS/MS method for determination of SP-141, a novel pyrido[b]indole anticancer agent, and its application to a mouse PK study.

scientific article

Anti-cancer effects of JKA97 are associated with its induction of cell apoptosis via a Bax-dependent and p53-independent pathway

scientific article published on 23 January 2008

Anti-cancer effects of JKA97 are associated with its induction of cell apoptosis via a Bax-dependent and p53-independent pathway.

scientific article

Application of CoMFA and CoMSIA 3D-QSAR and docking studies in optimization of mercaptobenzenesulfonamides as HIV-1 integrase inhibitors

scientific article

Asp746 to glycine change may have a greater influence than Cys751 to serine change in accounting for ligand selectivity between EGFR and HER-2 at the ATP site

scientific article published in May 2005

Chemoprevention activity of dipyridamole in the MMTV-PyMT transgenic mouse model of breast cancer.

scientific article published on 27 February 2013

CoMFA and CoMSIA 3D QSAR and docking studies on conformationally-restrained cinnamoyl HIV-1 integrase inhibitors: exploration of a binding mode at the active site

scientific article

CoMFA and CoMSIA 3D-QSAR studies on S(6)-(4-nitrobenzyl)mercaptopurine riboside (NBMPR) analogs as inhibitors of human equilibrative nucleoside transporter 1 (hENT1).

scientific article

Constrained NBMPR analogue synthesis, pharmacophore mapping and 3D-QSAR modeling of equilibrative nucleoside transporter 1 (ENT1) inhibitory activity

scientific article published on 30 January 2008

Design, Synthesis, and Evaluation of 2-Diethanolamino-4,8-diheptamethyleneimino-2-(N-aminoethyl-N-ethanolamino)-6-(N,N-diethanolamino)pyrimido[5,4-d]pyrimidine-fluorescein Conjugate (8MDP-fluor), As a Novel Equilibrative Nucleoside Transporter Probe ⬇️

scientific article published on May 13, 2011

Design, synthesis, and evaluation of 5'-S-aminoethyl-N(6)- azidobenzyl-5'-thioadenosine biotin conjugate: a bifunctional photoaffinity probe for the es nucleoside transporter

scientific article

Development and validation of a rapid HPLC method for quantitation of SP-141, a novel pyrido[b]indole anticancer agent, and an initial pharmacokinetic study in mice

scientific article

Dilazep analogues for the study of equilibrative nucleoside transporters 1 and 2 (ENT1 and ENT2).

scientific article

Dipyridamole analogs as pharmacological inhibitors of equilibrative nucleoside transporters. Identification of novel potent and selective inhibitors of the adenosine transporter function of human equilibrative nucleoside transporter 4 (hENT4).

scientific article published on 07 September 2013

Homology Model-Guided 3D-QSAR Studies of HIV-1 Integrase Inhibitors ⬇️

scientific article published on February 7, 2012

Identification of N10-substituted phenoxazines as potent and specific inhibitors of Akt signaling

scientific article published on 11 July 2005

Identification of a new class of MDM2 inhibitor that inhibits growth of orthotopic pancreatic tumors in mice

scientific article

Identification of the ENT1 antagonists dipyridamole and dilazep as amplifiers of oncolytic herpes simplex virus-1 replication

scientific article

Impact of resistance mutations on inhibitor binding to HIV-1 integrase

scientific article published on 21 November 2013

Inhibition of gastric tumor growth by a novel Hsp90 inhibitor ⬇️

scientific article published on February 13, 2013

Interaction of benzopyranone derivatives and related compounds with human concentrative nucleoside transporters 1, 2 and 3 heterologously expressed in porcine PK15 nucleoside transporter deficient cells. Structure-activity relationships and determin

scientific article

JKA97, a novel benzylidene analog of harmine, exerts anti-cancer effects by inducing G1 arrest, apoptosis, and p53-independent up-regulation of p21

scientific article

Molecule-kinase interaction map.

scientific article published in November 2005

Novel C2-purine position analogs of nitrobenzylmercaptopurine riboside as human equilibrative nucleoside transporter 1 inhibitors

scientific article published in September 2007

Novel halogenated nitrobenzylthioinosine analogs as es nucleoside transporter inhibitors

scientific article published in May 2004

Overview of novel anticancer drug targets

scientific article

Quantitative structure-activity relationship studies on nitrofuranyl anti-tubercular agents

scientific article published on 29 July 2008

Receptor-guided alignment-based comparative 3D-QSAR studies of benzylidene malonitrile tyrphostins as EGFR and HER-2 kinase inhibitors

scientific article published in October 2003

Small molecule antagonists of the MDM2 oncoprotein as anticancer agents

scientific article published in February 2005

Synthesis and biological evaluation of novel 5(H)-phenanthridin-6-ones, 5(H)-phenanthridin-6-one diketo acid, and polycyclic aromatic diketo acid analogs as new HIV-1 integrase inhibitors

scientific article published on 16 November 2006

Synthesis and biological evaluation of phloridzin analogs as human concentrative nucleoside transporter 3 (hCNT3) inhibitors

scientific article

Synthesis and flow cytometric evaluation of novel 1,2,3,4-tetrahydroisoquinoline conformationally constrained analogues of nitrobenzylmercaptopurine riboside (NBMPR) designed for probing its conformation when bound to the es nucleoside transporter

scientific article published in February 2003

Synthesis, biological evaluation and 3D-QSAR studies of 3-keto salicylic acid chalcones and related amides as novel HIV-1 integrase inhibitors

scientific article published on March 2011

Synthesis, docking, and biological studies of phenanthrene β-diketo acids as novel HIV-1 integrase inhibitors

scientific article published on 11 September 2013

Synthesis, flow cytometric evaluation, and identification of highly potent dipyridamole analogues as equilibrative nucleoside transporter 1 inhibitors

scientific article published on 18 July 2007

Targeting EGFR and HER-2 receptor tyrosine kinases for cancer drug discovery and development

scientific article published on September 2006

The pyrido[b]indole MDM2 inhibitor SP-141 exerts potent therapeutic effects in breast cancer models

scientific article published on 01 October 2014

Tyrosine phosphorylation of the human glutathione S-transferase P1 by epidermal growth factor receptor

scientific article published on 02 March 2009

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