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List of works by Francesco Manfredi

AN EXOSOME-BASED VACCINE PLATFORM IMPARTS CYTOTOXIC T LYMPHOCYTE IMMUNITY AGAINST VIRAL ANTIGENS.

scientific article published on 23 December 2017

Antitumor HPV E7-specific CTL activity elicited by in vivo engineered exosomes produced through DNA inoculation

scientific article published on 23 June 2017

Cell activation and HIV-1 replication in unstimulated CD4+ T lymphocytes ingesting exosomes from cells expressing defective HIV-1.

scientific article

DNA Vectors Generating Engineered Exosomes Potential CTL Vaccine Candidates Against AIDS, Hepatitis B, and Tumors

scientific article published on 01 November 2018

Engineered Extracellular Vesicles/Exosomes as a New Tool against Neurodegenerative Diseases

scientific article published on 09 June 2020

Engineered exosomes emerging from muscle cells break immune tolerance to HER2 in transgenic mice and induce antigen-specific CTLs upon challenge by human dendritic cells

scientific article published on 27 December 2017

Exosomes from human immunodeficiency virus type 1 (HIV-1)-infected cells license quiescent CD4+ T lymphocytes to replicate HIV-1 through a Nef- and ADAM17-dependent mechanism.

scientific article

Exploiting Manipulated Small Extracellular Vesicles to Subvert Immunosuppression at the Tumor Microenvironment through Mannose Receptor/CD206 Targeting

scientific article published on 31 August 2020

HPV-E7 delivered by engineered exosomes elicits a protective CD8⁺ T cell-mediated immune response

scientific article

Incorporation of Heterologous Proteins in Engineered Exosomes.

scientific article published on January 2016

Latent HIV-1 is activated by exosomes from cells infected with either replication-competent or defective HIV-1.

scientific article

The CD8⁺ T Cell-Mediated Immunity Induced by HPV-E6 Uploaded in Engineered Exosomes Is Improved by ISCOMATRIXTM Adjuvant.

scientific article

Trans-dissemination of exosomes from HIV-1-infected cells fosters both HIV-1 trans-infection in resting CD4(+) T lymphocytes and reactivation of the HIV-1 reservoir

scientific article published on 4 May 2017