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List of works by Jean-Pierre Routy

A Higher Frequency of NKG2A+ than of NKG2A- NK Cells Responds to Autologous HIV-Infected CD4 Cells irrespective of Whether or Not They Coexpress KIR3DL1.

scientific article published on 22 July 2015

A potentially protective role of IL-18 Binding Protein in HIV-infected Long-Term Non-Progressors

scientific article

Accounting for dropout reason in longitudinal studies with nonignorable dropout

scientific article

Altered differentiation is central to HIV-specific CD4+ T cell dysfunction in progressive disease

scientific article published on 15 July 2019

Anti-Gag antibodies gag HIV infection and slow disease progression

scientific article published on 01 June 2018

Antiretroviral Therapy in Primary HIV-1 Infection: Influences on Immune Activation and Gut Mucosal Barrier Dysfunction

scientific article published on July 2015

Antiretroviral drug transporters and metabolic enzymes in human testicular tissue: potential contribution to HIV-1 sanctuary site

scientific article published on 13 April 2016

Baseline Naive CD4+ T-cell Level Predicting Immune Reconstitution in Treated HIV-infected Late Presenters

scientific article published on January 2016

CD4:CD8 ratio as a frontier marker for clinical outcome, immune dysfunction and viral reservoir size in virologically suppressed HIV-positive patients

scientific article published on 29 June 2015

CMV seropositivity is associated with increased microbial translocation in people living with HIV and uninfected controls

scientific article published on 14 October 2019

CTL Clonotypes with Higher TCR Affinity Have Better Ability to Reduce the HIV Latent Reservoir

scientific article published on 26 June 2020

CXCL13 as a Biomarker of Immune Activation During Early and Chronic HIV Infection

article

Cannabis Consumption in People Living with HIV: Reasons for Use, Secondary Effects, and Opportunities for Health Education

scientific article published on 23 September 2019

Characterization of myeloid cell populations in human testes collected after sex reassignment surgery

scientific article published on 14 October 2017

Circulating (1→3)-β-D-glucan Is Associated With Immune Activation During Human Immunodeficiency Virus Infection

scientific article published in January 2020

Circulating LPS and (1→3)-β-D-Glucan: A Folie à Deux Contributing to HIV-Associated Immune Activation

article

Clinical Relevance of Kynurenine Pathway in HIV/AIDS: An Immune Checkpoint at the Crossroads of Metabolism and Inflammation

scientific article published on 06 May 2015

Combination antiretroviral therapy and indoleamine 2,3-dioxygenase in HIV infections: challenges and new opportunities.

scientific article published on July 2016

Comparative analysis of activation induced marker (AIM) assays for sensitive identification of antigen-specific CD4 T cells

scientific article

Correction: Distinct Tryptophan Catabolism and Th17/Treg Balance in HIV Progressors and Elite Controllers.

scientific article published on 9 January 2014

Current topics in HIV pathogenesis, part 2: Inflammation drives a Warburg-like effect on the metabolism of HIV-infected subjects

scientific article published on 27 January 2016

Daily variations of gut microbial translocation markers in ART-treated HIV-infected people

scientific article published on 12 May 2020

Dates of HIV infection can be estimated for seroprevalent patients by coalescent analysis of serial next-generation sequencing data

scientific article

Differential synthesis and release of IL-18 and IL-18 Binding Protein from human platelets and their implications for HIV infection

scientific article

Distinct tryptophan catabolism and Th17/Treg balance in HIV progressors and elite controllers

scientific article

Down-regulation of CTLA-4 by HIV-1 Nef protein

scientific article published on 23 January 2013

Drug resistance mutations and the cellular immune response: a valuable synergy for the development of novel immune therapies

scientific article published on March 2007

Dynamics and consequences of IL-21 production in HIV-infected individuals: a longitudinal and cross-sectional study.

scientific article

Early Initiation Rather Than Prolonged Duration of Antiretroviral Therapy in HIV Infection Contributes to the Normalization of CD8 T-Cell Counts

scientific article

Effect of IL-7 Therapy on Phospho-Ribosomal Protein S6 and TRAF1 Expression in HIV-Specific CD8 T Cells in Patients Receiving Antiretroviral Therapy

scientific article published on 8 December 2017

Effect of metformin on the size of the HIV reservoir in non-diabetic ART-treated individuals: single-arm non-randomised Lilac pilot study protocol

article

Elevated Abundance, Size, and MicroRNA Content of Plasma Extracellular Vesicles in Viremic HIV-1+ Patients: Correlations With Known Markers of Disease Progression

scientific article

Elevation and persistence of CD8 T-cells in HIV infection: the Achilles heel in the ART era

scientific article

Evaluation of a project to engage patients in the development of a patient-reported measure for HIV care (the I-Score Study)

article

Failed immune responses across multiple pathologies share pan-tumor and circulating lymphocytic targets

scientific article published on 26 March 2019

French HIV experts on early antiretroviral treatment for prevention: uncertainty and heterogeneity

scientific article

Genetic basis of hypersusceptibility to protease inhibitors and low replicative capacity of human immunodeficiency virus type 1 strains in primary infection

scientific article published on March 2004

Glucan rich nutrition does not increase gut translocation of Beta glucan

scientific article published on 11 August 2020

HIV Diversity and Genetic Compartmentalization in Blood and Testes during Suppressive Antiretroviral Therapy

scientific article published on 13 August 2019

HIV and the gut microbiota, partners in crime: breaking the vicious cycle to unearth new therapeutic targets.

scientific article

HIV experts on the decision to use early ART for prevention in France: are we there yet?

scientific article published on 25 May 2012

HIV immunotherapy comes of age: implications for prevention, treatment and cure

scientific article

HIV induces production of IL-18 from intestinal epithelial cells that increases intestinal permeability and microbial translocation.

scientific article published on 30 March 2018

HIV persists in CCR6+CD4+ T cells from colon and blood during antiretroviral therapy

scientific article

HIV protective KIR3DL1/S1-HLA-B genotypes influence NK cell-mediated inhibition of HIV replication in autologous CD4 targets

scientific article published on 16 January 2014

Highlights from the 2016 International Symposium on HIV & Emerging Infectious Diseases (ISHEID): 25-27 May, Marseille, France

scientific article

Highlights from the Seventh International Workshop on HIV Persistence during Therapy, 8-11 December 2015, Miami, Florida, USA

scientific article

Human immunodeficiency virus (HIV)-specific effector CD8 T cell activity in patients with primary HIV infection

scientific article published on 20 February 2002

Human immunodeficiency virus type 1-specific CD8+ T-cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T cells

scientific article published on 20 May 2009

IL-21 enhances NK cell functions and survival in healthy and HIV-infected patients with minimal stimulation of viral replication

scientific article

Identification of novel HIV-1 dependency factors in primary CCR4(+)CCR6(+)Th17 cells via a genome-wide transcriptional approach

scientific article

Imbalanced production of IL-18 and its antagonist in human diseases, and its implications for HIV-1 infection

scientific article

Immune Checkpoint Blockade Restores HIV-Specific CD4 T Cell Help for NK Cells

scientific article published on 22 June 2018

Immune Suppression by Myeloid Cells in HIV Infection: New Targets for Immunotherapy

scientific article published on 29 December 2014

Immune tolerance properties of the testicular tissue as a viral sanctuary site in ART-treated HIV-infected adults

scientific article published on 24 September 2016

Immunosuppressive Tryptophan Catabolism and Gut Mucosal Dysfunction Following Early HIV Infection

scientific article published on 23 January 2015

Impact of autologous dendritic cell-based immunotherapy (AGS-004) on B- and T-cell subset changes and immune activation in HIV-infected patients receiving antiretroviral therapy

scientific article published on December 2013

Impaired Th17 polarization of phenotypically naive CD4(+) T-cells during chronic HIV-1 infection and potential restoration with early ART

scientific article published on 30 April 2015

Improving HIV Outgrowth by Optimizing Cell-Culture Conditions and Supplementing With all-trans Retinoic Acid

scientific article published on 15 May 2020

Influence of Hepatitis C Virus Sustained Virological Response on Immunosuppressive Tryptophan Catabolism in ART-Treated HIV/HCV Coinfected Patients.

scientific article published on 21 September 2015

Interleukin-7 promotes HIV persistence during antiretroviral therapy

scientific article published on 15 April 2013

Kynurenine Reduces Memory CD4 T-Cell Survival by Interfering with Interleukin-2 Signaling Early during HIV-1 Infection

scientific article published on 29 June 2016

Memory CCR6+CD4+ T cells are preferential targets for productive HIV type 1 infection regardless of their expression of integrin β7.

scientific article published on 11 March 2011

Minimal interference: A basis for selecting ART for prevention with positives

scientific article published on 11 February 2013

NK Cells Expressing the Inhibitory Killer Immunoglobulin-Like Receptors (iKIR) KIR2DL1, KIR2DL3 and KIR3DL1 Are Less Likely to Be CD16+ than Their iKIR Negative Counterparts

scientific article

Nasal Nitric Oxide Levels in HIV Infection: A Cross-Sectional Study.

scientific article

Nef promotes evasion of human immunodeficiency virus type 1-infected cells from the CTLA-4-mediated inhibition of T-cell activation

scientific article

New insights into the heterogeneity of Th17 subsets contributing to HIV-1 persistence during antiretroviral therapy

scientific article published on 24 August 2016

Nonalcoholic fatty liver disease diagnosed by transient elastography with controlled attenuation parameter in unselected HIV monoinfected patients.

scientific article published on 6 September 2016

Oral cannabinoids in people living with HIV on effective antiretroviral therapy: CTN PT028-study protocol for a pilot randomised trial to assess safety, tolerability and effect on immune activation

article

Overcoming the challenge of diagnosis of early HIV infection: a stepping stone to optimal patient management

scientific article published in October 2015

PD-1 blockade potentiates HIV latency reversal ex vivo in CD4 T cells from ART-suppressed individuals

article

Peripheral blood CCR4+CCR6+ and CXCR3+CCR6+CD4+ T cells are highly permissive to HIV-1 infection

scientific article

Persistence and fitness of multidrug-resistant human immunodeficiency virus type 1 acquired in primary infection

scientific article

Persistent expansion and Th1-like skewing of HIV-specific circulating T follicular helper cells during antiretroviral therapy

scientific article published on 05 April 2020

Plasma Indoleamine 2,3-Dioxygenase Activity Is Associated With the Size of the Human Immunodeficiency Virus Reservoir in Patients Receiving Antiretroviral Therapy

scientific article published on 01 April 2019

Plasma Level of Soluble ST2 in Chronically Infected HIV-1 Patients with Suppressed Viremia

scientific article published on 26 April 2017

Potential contribution of gut microbiota and systemic inflammation on HIV vaccine effectiveness and vaccine design

scientific article published on 12 September 2017

Quantifying Anti-HIV Envelope-Specific Antibodies in Plasma from HIV Infected Individuals

scientific article published on 28 May 2019

Recognition of a defined region within p24 gag by CD8+ T cells during primary human immunodeficiency virus type 1 infection in individuals expressing protective HLA class I alleles

scientific article published on 9 May 2007

Regulatory T cells negatively affect IL-2 production of effector T cells through CD39/adenosine pathway in HIV infection

scientific article

Reversing Gut Damage in HIV Infection: Using Non-Human Primate Models to Instruct Clinical Research

scientific article

Role of interleukin-18 in the development and pathogenesis of AIDS.

scientific article published on July 2009

Sex, race, and geographic region influence clinical outcomes following primary HIV-1 infection

scientific article

Single-cell TCR sequencing reveals phenotypically diverse clonally expanded cells harboring inducible HIV proviruses during ART

scientific article published on 14 August 2020

Single-cell characterization and quantification of translation-competent viral reservoirs in treated and untreated HIV infection

article

Socio-economic status and time trends associated with early ART initiation following primary HIV infection in Montreal, Canada: 1996 to 2015.

scientific article published in February 2018

Targeting the interleukin-17 pathway to prevent acute respiratory distress syndrome associated with SARS-CoV-2 infection

scientific article published on 17 June 2020

Temporal effect of HLA-B*57 on viral control during primary HIV-1 infection

scientific article

The Biology of Monocytes and Dendritic Cells: Contribution to HIV Pathogenesis

scientific article published on 6 February 2018

The Control of HIV After Antiretroviral Medication Pause (CHAMP) Study: Posttreatment Controllers Identified From 14 Clinical Studies

scientific article published on 01 November 2018

The Dynamic Role of the IL-33/ST2 Axis in Chronic Viral-infections: Alarming and Adjuvanting the Immune Response

scientific article

The Kynurenine Pathway Is a Double-Edged Sword in Immune-Privileged Sites and in Cancer: Implications for Immunotherapy

scientific article

The Th17 Lineage: From Barrier Surfaces Homeostasis to Autoimmunity, Cancer, and HIV-1 Pathogenesis

scientific article published on 19 October 2017

The anti-inflammatory IL-37/SIGIRR axis is functionally compromised in HIV infection

scientific article published on 01 September 2019

The colocalization potential of HIV-specific CD8+ and CD4+ T-cells is mediated by integrin β7 but not CCR6 and regulated by retinoic acid

scientific article

The evaluation of risk-benefit ratio for gut tissue sampling in HIV cure research

scientific article published in October 2017

The plasma levels of soluble ST2 as a marker of gut mucosal damage in early HIV infection

scientific article published on 31 March 2016

The role of extended-release niacin on immune activation and neurocognition in HIV-infected patients treated with antiretroviral therapy - CTN PT006: study protocol for a randomized controlled trial

scientific article

Tolerability and efficacy of PI versus NNRTI-based regimens in subjects receiving HAART during acute or early HIV infection

scientific article

Towards an HIV cure: a global scientific strategy

scientific article

Transcriptional profiling reveals molecular signatures associated with HIV permissiveness in Th1Th17 cells and identifies peroxisome proliferator-activated receptor gamma as an intrinsic negative regulator of viral replication

scientific article published on 21 December 2013

Transmission networks of drug resistance acquired in primary/early stage HIV infection

scientific article

Tryptophan Catabolism in Chronic Viral Infections: Handling Uninvited Guests

scientific article (publication date: 2015)

Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction

scientific article

Use of (1→3)-β-d-glucan for diagnosis and management of invasive mycoses in HIV-infected patients

scientific article published on 05 July 2018

Variability in the PR and RT genes of HIV-1 isolated from recently infected subjects

scientific article

Very early antiretroviral therapy permits CD8 T cells to keep HIV reservoirs at bay.

scientific article published in November 2017

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