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List of works by Jacques Magdalou

* Hypoxia for Mesenchymal Stem Cell Expansion and Differentiation: The Best Way for Enhancing TGFß-Induced Chondrogenesis and Preventing Calcifications in Alginate Beads

scientific article published on 7 April 2017

A simple two dimensional culture method to study the hypertrophic differentiation of rat articular chondrocytes

scientific article published in January 2015

Angelica Sinensis polysaccharides stimulated UDP-sugar synthase genes through promoting gene expression of IGF-1 and IGF1R in chondrocytes: promoting anti-osteoarthritic activity

scientific article

Angelica sinensis and osteoarthritis: a natural therapeutic link?

scientific article published on January 2015

Assessment of catechol induction and glucuronidation in rat liver microsomes

scientific article published on 15 September 2004

Autoantibodies directed against the UDP-glucuronosyltransferases in human autoimmune hepatitis

scientific article

Biochemical and thermodynamic characterization of mutated β1,4-galactosyltransferase 7 involved in the progeroid form of the Ehlers–Danlos syndrome ⬇️

scientific article published on December 1, 2010

Biomechanical and biochemical protective effect of low-level laser therapy for Achilles tendinitis.

scientific article

C-propeptides of procollagens I alpha 1 and II that differentially accumulate in enchondromas versus chondrosarcomas regulate tumor cell survival and migration

scientific article published on 11 May 2010

CYP 2C19 and UDP-glucuronosyltransferases not only for drugs but also for endobiotics

scientific article published on 01 January 2014

Caffeine-induced activated glucocorticoid metabolism in the hippocampus causes hypothalamic-pituitary-adrenal axis inhibition in fetal rats.

scientific article

Caffeine-induced fetal rat over-exposure to maternal glucocorticoid and histone methylation of liver IGF-1 might cause skeletal growth retardation ⬇️

scientific article published on September 17, 2012

Carboxyl nonsteroidal anti-inflammatory drugs are efficiently glucuronidated by microsomes of the human gastrointestinal tract.

scientific article published in November 2004

Characterization of catechol glucuronidation in rat liver

scientific article published in February 2002

Chondrocalcin is internalized by chondrocytes and triggers cartilage destruction via an interleukin-1β-dependent pathway ⬇️

scientific article published on July 10, 2013

Chondroitin sulfate N-acetylgalactosaminyltransferase-1 (CSGalNAcT-1) involved in chondroitin sulfate initiation: Impact of sulfation on activity and specificity.

scientific article

Comparison of electrospray, atmospheric pressure chemical ionization, and atmospheric pressure photoionization in the identification of apomorphine, dobutamine, and entacapone phase II metabolites in biological samples

scientific article

Correction: TNF/TNFR signal transduction pathway-mediated anti-apoptosis and anti-inflammatory effects of sodium ferulate on IL-1β- induced rat osteoarthritis chondrocytes in vitro

scientific article published on 10 May 2013

Covalent attachment of epoxide hydrolase to dextran

Cucurbitacins from Ecballium elaterium juice increase the binding of bilirubin and ibuprofen to albumin in human plasma

scientific article published on 21 May 2007

Cytotoxic effects of the quinolone levofloxacin on rabbit meniscus cells ⬇️

scientific article published on July 1, 2013

Differential induction profile of drug-metabolizing enzymes after treatment with hypolipidaemic agents

Effect of nicotine on chondrogenic differentiation of rat bone marrow mesenchymal stem cells in alginate bead culture ⬇️

scientific article published on January 1, 2012

Effect of nicotine on the proliferation and chondrogenic differentiation of the human Wharton's jelly mesenchymal stem cells

scientific article

Effect ofAngelica sinensisPolysaccharides on OsteoarthritisIn VivoandIn Vitro: A Possible Mechanism to Promote Proteoglycans Synthesis ⬇️

scientific article published on 04 June 2013

Effects and Interactions of Prenatal Ethanol Exposure, a Post-Weaning High-Fat Diet and Gender on Adult Hypercholesterolemia Occurrence in Offspring Rats

scientific article published on 23 November 2017

Effects of adenovirus-mediated bFGF, IL-1Ra and IGF-1 gene transfer on human osteoarthritic chondrocytes and osteoarthritis in rabbits ⬇️

scientific article published on October 31, 2010

Establishment of a reliable method for direct proteome characterization of human articular cartilage

scientific article published on 09 May 2006

Evidence of calcium-dependent pathway in the regulation of human beta1,3-glucuronosyltransferase-1 (GlcAT-I) gene expression: a key enzyme in proteoglycan synthesis

scientific article

Fetal rat metabonome alteration by prenatal caffeine ingestion probably due to the increased circulatory glucocorticoid level and altered peripheral glucose and lipid metabolic pathways ⬇️

scientific article published on May 11, 2012

Gender-specific increase in susceptibility to metabolic syndrome of offspring rats after prenatal caffeine exposure with post-weaning high-fat diet

scientific article published on 11 March 2015

Glucuronidation of catechols by human hepatic, gastric, and intestinal microsomal UDP-glucuronosyltransferases (UGT) and recombinant UGT1A6, UGT1A9, and UGT2B7

scientific article published on 01 March 2003

Glucuronidation of odorant molecules in the rat olfactory system: activity, expression and age-linked modifications of UDP-glucuronosyltransferase isoforms, UGT1A6 and UGT2A1, and relation to mitral cell activity

scientific article published in November 2002

Identification of aspartic acid and histidine residues mediating the reaction mechanism and the substrate specificity of the human UDP-glucuronosyltransferases 1A.

scientific article published on 23 October 2007

Identification of the Human UDP-glucuronosyltransferase Isoforms Involved in the Glucuronidation of the Phytochemical Ferulic Acid ⬇️

scientific article published on March 14, 2011

Immobilization of epoxide hydrolase purified from rat liver microsomes

In malignant cartilagenous tumors, immunohistochemical expression of procollagen PC1CP peptide is higher and that of PC2CP lower than in benign cartilaginous lesions

scientific article published on 23 June 2015

In vitro evaluation of glucuronidation of monohydroxylated aglycones related to quantum chemically-calculated parameters

In vitro stereoselective covalent binding of carprofen glucuronides to human serum albumin: characterization of the mechanism

scientific article published on January 1, 2003

Increased expression of matrilin-3 not only in osteoarthritic articular cartilage but also in cartilage-forming tumors, and down-regulation of SOX9 via epidermal growth factor domain 1-dependent signaling.

scientific article

Increased susceptibility of prenatal food restricted offspring to high-fat diet-induced nonalcoholic fatty liver disease is intrauterine programmed

scientific article published on 16 August 2016

Influencing factors, underlying mechanism and interactions affecting hypercholesterolemia in adult offspring with caffeine exposure during pregnancy.

scientific article

Insights on membrane topology and structure/function of UDP-glucuronosyltransferases

scientific article published on February 2010

Interaction of cucurbitacins with human serum albumin: Thermodynamic characteristics and influence on the binding of site specific ligands

scientific article published on 25 March 2009

Intrauterine programming of Glucocorticoid-Insulin-Like Growth Factor 1 axis-mediated developmental origin of osteoporosis susceptibility in female offspring rats of prenatal caffeine exposure

scientific article published on 28 September 2018

Label-free relative quantification applied to LC-MALDI acquisition for rapid analysis of chondrocyte secretion modulation.

scientific article

Low-level laser therapy in collagenase-induced Achilles tendinitis in rats: analyses of biochemical and biomechanical aspects

scientific article published on 05 June 2012

Matrilin-3 switches from anti- to pro-anabolic upon integration to the extracellular matrix.

scientific article published on 10 April 2012

Metabolism of Parabens (4-Hydroxybenzoic Acid Esters) by Hepatic Esterases and UDP-Glucuronosyltransferases in Man ⬇️

scientific article published on January 1, 2010

Mitogen-inducible gene-6 partly mediates the inhibitory effects of prenatal dexamethasone exposure on endochondral ossification in long bones of fetal rats

scientific article published on 29 April 2016

Modifications of the glycosaminoglycan-linkage region of proteoglycans: phosphorylation and sulfation determine the activity of the human beta1,4-galactosyltransferase 7 and beta1,3-glucuronosyltransferase I.

scientific article

Modulation of xylosyltransferase I expression provides a mechanism regulating glycosaminoglycan chain synthesis during cartilage destruction and repair

scientific journal article

Molecular basis for acceptor substrate specificity of the human beta1,3-glucuronosyltransferases GlcAT-I and GlcAT-P involved in glycosaminoglycan and HNK-1 carbohydrate epitope biosynthesis, respectively

scientific article published on 13 June 2007

Nicotine-induced retardation of chondrogenesis through down-regulation of IGF-1 signaling pathway to inhibit matrix synthesis of growth plate chondrocytes in fetal rats ⬇️

scientific article published on February 27, 2013

Osteogenic differentiation of human bone marrow mesenchymal stem cells in hydrogel containing nacre powder.

scientific article published on 3 April 2013

Phosphorylation and sulfation of oligosaccharide substrates critically influence the activity of human beta1,4-galactosyltransferase 7 (GalT-I) and beta1,3-glucuronosyltransferase I (GlcAT-I) involved in the biosynthesis of the glycosaminoglycan-pro

scientific article

Phylogenetic and mutational analyses reveal key residues for UDP-glucuronic acid binding and activity of beta1,3-glucuronosyltransferase I (GlcAT-I)

scientific article

Prenatal caffeine exposure induces a poor quality of articular cartilage in male adult offspring rats via cholesterol accumulation in cartilage

scientific article

Prenatal ethanol exposure increases osteoarthritis susceptibility in female rat offspring by programming a low-functioning IGF-1 signaling pathway

scientific article

Prenatal ethanol exposure induces the osteoarthritis-like phenotype in female adult offspring rats with a post-weaning high-fat diet and its intrauterine programming mechanisms of cholesterol metabolism

scientific article published on 25 July 2015

Prenatal ethanol exposure programs an increased susceptibility of non-alcoholic fatty liver disease in female adult offspring rats

scientific article published on 22 November 2013

Prenatal food restriction induces poor-quality articular cartilage in female rat offspring fed a post-weaning high-fat diet and its intra-uterine programming mechanisms

scientific article published on 29 September 2016

Prenatal nicotine exposure enhances the susceptibility to metabolic syndrome in adult offspring rats fed high-fat diet via alteration of HPA axis-associated neuroendocrine metabolic programming

scientific article

Prenatal nicotine exposure induces poor articular cartilage quality in female adult offspring fed a high-fat diet and the intrauterine programming mechanisms

scientific article

Prenatal nicotine exposure intergenerationally programs imperfect articular cartilage via histone deacetylation through maternal lineage

scientific article published on 13 April 2018

Preparation and characterization of liposomes incorporating cucurbitacin E, a natural cytotoxic triterpene ⬇️

scientific article published on March 21, 2013

Purification and characterization of a soluble form of the recombinant human galactose-beta1,3-glucuronosyltransferase I expressed in the yeast Pichia pastoris

scientific article

Regulation of xylosyltransferase I gene expression by interleukin 1β in human primary chondrocyte cells: mechanism and impact on proteoglycan synthesis

scientific article published on 5 December 2012

Response to 'TNF/TNFR signal transduction pathway-mediated anti-apoptosis and anti-inflammatory effects of sodium ferulate on IL-1β-induced rat osteoarthritis chondrocytes in vitro' - authors' reply ⬇️

scientific article published on January 1, 2013

Resveratrol is efficiently glucuronidated by UDP-glucuronosyltransferases in the human gastrointestinal tract and in Caco-2 cells

scientific article published in May 2006

Reviewing the binding of a series of parabens to human serum albumin

scientific article published on 25 February 2013

Stability of cucurbitacin E in human plasma: chemical hydrolysis and role of plasma esterases

scientific article published in October 2009

Structure of UDP-glucuronosyltransferases in membranes

scientific article

Subchondral bone dysplasia partly participates in prenatal dexamethasone induced-osteoarthritis susceptibility in female offspring rats

scientific article published on 18 January 2020

Substrate specificity of the human UDP-glucuronosyltransferase UGT2B4 and UGT2B7. Identification of a critical aromatic amino acid residue at position 33

scientific article

Synergistic antifibrotic effect of verapamil and interferon-gamma in rats: partially based on enhanced verapamil oral bioavailability

scientific article published in April 2010

TNF/TNFR signal transduction pathway-mediated anti-apoptosis and anti-inflammatory effects of sodium ferulate on IL-1β-induced rat osteoarthritis chondrocytes in vitro ⬇️

scientific article published on November 7, 2012

The UDP-glucuronosyltransferases of the blood-brain barrier: their role in drug metabolism and detoxication

scientific article

The critical role of UDP-galactose-4-epimerase in osteoarthritis: modulating proteoglycans synthesis of the articular chondrocytes

scientific article published on 6 September 2014

The cucurbitacins E, D and I: investigation of their cytotoxicity toward human chondrosarcoma SW 1353 cell line and their biotransformation in man liver

scientific article published on 27 November 2012

The donor substrate specificity of the human beta 1,3-glucuronosyltransferase I toward UDP-glucuronic acid is determined by two crucial histidine and arginine residues

scientific article (publication date: 12 July 2002)

The effects of levofloxacin on rabbit anterior cruciate ligament cells in vitro

scientific article published on 27 August 2011

The effects of levofloxacin on rabbit fibroblast-like synoviocytes in vitro ⬇️

scientific article published on October 12, 2012

The functional glycosyltransferase signature sequence of the human beta 1,3-glucuronosyltransferase is a XDD motif

scientific article

The human UDP-glucuronosyltransferases: structural aspects and drug glucuronidation

scientific article published on November 2003

The importance of cysteine 126 in the human liver UDP-glucuronosyltransferase UGT1A6.

scientific article

The stop transfer sequence of the human UDP-glucuronosyltransferase 1A determines localization to the endoplasmic reticulum by both static retention and retrieval mechanisms

scientific article published in February 2005

The use of hepatocytes to investigate UDP-glucuronosyltransferases and sulfotransferases

scientific article published on 01 January 2010

Thermodynamic insights into the structural basis governing the donor substrate recognition by human beta1,4-galactosyltransferase 7.

scientific article published in March 2009

UDP-glucose dehydrogenase modulates proteoglycan synthesis in articular chondrocytes: its possible involvement and regulation in osteoarthritis

scientific article

Xylosyltransferase-I regulates glycosaminoglycan synthesis during the pathogenic process of human osteoarthritis

scientific article

[Agrecan and articular cartilage: assessment of glycosyltransferases for the restoration of cartilage matrix in osteoarthritis]

scientific article published on 19 December 2008

[Chondrocyte glycosyltransferases: new pharmacological targets for degenerative diseases of articular cartilage?]

scientific article published on 01 October 2006

[Stimulation of proteoglycan synthesis towards cartilage repair]

scientific article published on 01 May 2005

cis- and trans-Resveratrol are glucuronidated in rat brain, olfactory mucosa and cultured astrocytes

scientific article published on 18 June 2007

p-Hydroxybenzoate esters metabolism in MCF7 breast cancer cells

scientific article published on 14 August 2012

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