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List of works by Jacques Magdalou

1-50 of 96 results

Phosphorylation and sulfation of oligosaccharide substrates critically influence the activity of human beta1,4-galactosyltransferase 7 (GalT-I) and beta1,3-glucuronosyltransferase I (GlcAT-I) involved in the biosynthesis of the glycosaminoglycan-pro

scientific article

Effects of adenovirus-mediated bFGF, IL-1Ra and IGF-1 gene transfer on human osteoarthritic chondrocytes and osteoarthritis in rabbits

scientific article published on October 31, 2010

Caffeine-induced activated glucocorticoid metabolism in the hippocampus causes hypothalamic-pituitary-adrenal axis inhibition in fetal rats.

scientific article

Caffeine-induced fetal rat over-exposure to maternal glucocorticoid and histone methylation of liver IGF-1 might cause skeletal growth retardation

scientific article published on September 17, 2012

Low-level laser therapy in collagenase-induced Achilles tendinitis in rats: analyses of biochemical and biomechanical aspects

scientific article published on 05 June 2012

Glucuronidation of odorant molecules in the rat olfactory system: activity, expression and age-linked modifications of UDP-glucuronosyltransferase isoforms, UGT1A6 and UGT2A1, and relation to mitral cell activity

scientific article published in November 2002

Establishment of a reliable method for direct proteome characterization of human articular cartilage

scientific article published on 09 May 2006

Resveratrol is efficiently glucuronidated by UDP-glucuronosyltransferases in the human gastrointestinal tract and in Caco-2 cells

scientific article published in May 2006

TNF/TNFR signal transduction pathway-mediated anti-apoptosis and anti-inflammatory effects of sodium ferulate on IL-1β-induced rat osteoarthritis chondrocytes in vitro

scientific article published on November 7, 2012

Comparison of electrospray, atmospheric pressure chemical ionization, and atmospheric pressure photoionization in the identification of apomorphine, dobutamine, and entacapone phase II metabolites in biological samples

scientific article

The donor substrate specificity of the human beta 1,3-glucuronosyltransferase I toward UDP-glucuronic acid is determined by two crucial histidine and arginine residues

scientific article (publication date: 12 July 2002)

Prenatal ethanol exposure programs an increased susceptibility of non-alcoholic fatty liver disease in female adult offspring rats

scientific article published on November 22, 2013

Structure of UDP-glucuronosyltransferases in membranes

scientific article

The UDP-glucuronosyltransferases of the blood-brain barrier: their role in drug metabolism and detoxication

scientific article published on October 28, 2014

The human UDP-glucuronosyltransferases: structural aspects and drug glucuronidation

scientific article published on November 2003

Metabolism of Parabens (4-Hydroxybenzoic Acid Esters) by Hepatic Esterases and UDP-Glucuronosyltransferases in Man

scientific article published on January 1, 2010

Biochemical and thermodynamic characterization of mutated β1,4-galactosyltransferase 7 involved in the progeroid form of the Ehlers–Danlos syndrome

scientific article published on December 1, 2010

Identification of aspartic acid and histidine residues mediating the reaction mechanism and the substrate specificity of the human UDP-glucuronosyltransferases 1A.

scientific article published on 23 October 2007

Fetal rat metabonome alteration by prenatal caffeine ingestion probably due to the increased circulatory glucocorticoid level and altered peripheral glucose and lipid metabolic pathways

scientific article published on May 11, 2012

Modulation of xylosyltransferase I expression provides a mechanism regulating glycosaminoglycan chain synthesis during cartilage destruction and repair

scientific journal article

The stop transfer sequence of the human UDP-glucuronosyltransferase 1A determines localization to the endoplasmic reticulum by both static retention and retrieval mechanisms

scientific article published in February 2005

Thermodynamic insights into the structural basis governing the donor substrate recognition by human beta1,4-galactosyltransferase 7.

scientific article published in March 2009

Characterization of catechol glucuronidation in rat liver

scientific article published in February 2002

C-propeptides of procollagens I alpha 1 and II that differentially accumulate in enchondromas versus chondrosarcomas regulate tumor cell survival and migration

scientific article published on 11 May 2010

Regulation of xylosyltransferase I gene expression by interleukin 1β in human primary chondrocyte cells: mechanism and impact on proteoglycan synthesis

scientific article published on 5 December 2012

Substrate specificity of the human UDP-glucuronosyltransferase UGT2B4 and UGT2B7. Identification of a critical aromatic amino acid residue at position 33

scientific article

The functional glycosyltransferase signature sequence of the human beta 1,3-glucuronosyltransferase is a XDD motif

scientific article

Xylosyltransferase-I regulates glycosaminoglycan synthesis during the pathogenic process of human osteoarthritis

scientific article

Increased expression of matrilin-3 not only in osteoarthritic articular cartilage but also in cartilage-forming tumors, and down-regulation of SOX9 via epidermal growth factor domain 1-dependent signaling

scientific article

Insights on membrane topology and structure/function of UDP-glucuronosyltransferases

scientific article published on February 2010

The importance of cysteine 126 in the human liver UDP-glucuronosyltransferase UGT1A6.

scientific article

Autoantibodies directed against the UDP-glucuronosyltransferases in human autoimmune hepatitis

scientific article

The effects of levofloxacin on rabbit fibroblast-like synoviocytes in vitro

scientific article published on October 12, 2012

Carboxyl nonsteroidal anti-inflammatory drugs are efficiently glucuronidated by microsomes of the human gastrointestinal tract.

scientific article published in November 2004

Evidence of calcium-dependent pathway in the regulation of human beta1,3-glucuronosyltransferase-1 (GlcAT-I) gene expression: a key enzyme in proteoglycan synthesis

scientific article

Effect ofAngelica sinensisPolysaccharides on OsteoarthritisIn VivoandIn Vitro: A Possible Mechanism to Promote Proteoglycans Synthesis

scientific article published on 04 June 2013

Nicotine-induced retardation of chondrogenesis through down-regulation of IGF-1 signaling pathway to inhibit matrix synthesis of growth plate chondrocytes in fetal rats

scientific article published on February 27, 2013

The cucurbitacins E, D and I: investigation of their cytotoxicity toward human chondrosarcoma SW 1353 cell line and their biotransformation in man liver

scientific article published on 27 November 2012

Glucuronidation of catechols by human hepatic, gastric, and intestinal microsomal UDP-glucuronosyltransferases (UGT) and recombinant UGT1A6, UGT1A9, and UGT2B7

scientific article published on 01 March 2003

Phylogenetic and mutational analyses reveal key residues for UDP-glucuronic acid binding and activity of beta1,3-glucuronosyltransferase I (GlcAT-I)

scientific article

Matrilin-3 switches from anti- to pro-anabolic upon integration to the extracellular matrix.

scientific article published on 10 April 2012

Effect of nicotine on chondrogenic differentiation of rat bone marrow mesenchymal stem cells in alginate bead culture

scientific article published on January 1, 2012

p-Hydroxybenzoate esters metabolism in MCF7 breast cancer cells

scientific article published on 14 August 2012

Preparation and characterization of liposomes incorporating cucurbitacin E, a natural cytotoxic triterpene

scientific article published on March 21, 2013

Osteogenic differentiation of human bone marrow mesenchymal stem cells in hydrogel containing nacre powder.

scientific article published on 3 April 2013

Biomechanical and biochemical protective effect of low-level laser therapy for Achilles tendinitis.

scientific article

Label-free relative quantification applied to LC-MALDI acquisition for rapid analysis of chondrocyte secretion modulation.

scientific article

* Hypoxia for Mesenchymal Stem Cell Expansion and Differentiation: The Best Way for Enhancing TGFß-Induced Chondrogenesis and Preventing Calcifications in Alginate Beads

scientific article published on 7 April 2017

Chondroitin sulfate N-acetylgalactosaminyltransferase-1 (CSGalNAcT-1) involved in chondroitin sulfate initiation: Impact of sulfation on activity and specificity.

scientific article

Identification of the Human UDP-glucuronosyltransferase Isoforms Involved in the Glucuronidation of the Phytochemical Ferulic Acid

scientific article published on March 14, 2011