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List of works by Liang Chen

A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo.

scientific article published on 12 February 2018

A new ALK inhibitor overcomes resistance to first- and second-generation inhibitors in NSCLC

scientific article published on 30 November 2021

A tumor suppressor enhancing module orchestrated by GATA4 denotes a therapeutic opportunity for GATA4 deficient HCC patients

scientific article published on 01 January 2020

An EGFR/PI3K/AKT axis promotes accumulation of the Rac1-GEF Tiam1 that is critical in EGFR-driven tumorigenesis.

scientific article published on 9 March 2015

Blocking interaction between SHP2 and PD-1 denotes a novel opportunity for developing PD-1 inhibitors

scientific article published on 11 May 2020

Cetuximab response of lung cancer-derived EGF receptor mutants is associated with asymmetric dimerization

scientific article published on 24 September 2013

Discovery of Novel Inhibitor for WNT/β-Catenin Pathway by Tankyrase 1/2 Structure-Based Virtual Screening

scientific article published on 06 April 2020

EGFR kinase domain mutation positive lung cancers are sensitive to intrapleural perfusion with hyperthermic chemotherapy (IPHC) complete treatment.

scientific article published on 8 December 2015

In vivo CRISPR screening unveils histone demethylase UTX as an important epigenetic regulator in lung tumorigenesis

scientific article published on 9 April 2018

Mup-knockout mice generated through CRISPR/Cas9-mediated deletion for use in urinary protein analysis

scientific article published on 06 February 2016

Overexpression of wildtype EGFR is tumorigenic and denotes a therapeutic target in non-small cell lung cancer.

scientific article published on 4 December 2015

The impact of the MYB-NFIB fusion proto-oncogene in vivo.

scientific article published on 18 May 2016

Tumor driven by gain-of-function HER2 H878Y mutant is highly sensitive to HER2 inhibitor

scientific article published on 8 September 2015

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